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Gene Gene information from NCBI Gene database.
Entrez ID 7009
Gene name Transmembrane BAX inhibitor motif containing 6
Gene symbol TMBIM6
Synonyms (NCBI Gene)
BAXI1BI-1TEGT
Chromosome 12
Chromosome location 12q13.12
miRNA miRNA information provided by mirtarbase database.
2071 Show/Hide all (2071)
miRTarBase ID miRNA Experiments Reference
MIRT020530 hsa-miR-155-5p Proteomics 18668040
MIRT031401 hsa-miR-16-5p Proteomics 18668040
MIRT050638 hsa-miR-19b-3p CLASH 23622248
MIRT045127 hsa-miR-186-5p CLASH 23622248
MIRT042252 hsa-miR-484 CLASH 23622248
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
47 Show/Hide all (47)
GO ID Ontology Definition Evidence Reference
GO:0000122 Process Negative regulation of transcription by RNA polymerase II IEA
GO:0002638 Process Negative regulation of immunoglobulin production IEA
GO:0005262 Function Calcium channel activity IBA
GO:0005515 Function Protein binding IPI 9660918, 28514442, 30559186, 32296183, 33961781
GO:0005634 Component Nucleus TAS 8530040
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
600748 11723 ENSG00000139644
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
P55061
Protein name Bax inhibitor 1 (BI-1) (Testis-enhanced gene transcript protein) (Transmembrane BAX inhibitor motif-containing protein 6)
Protein function Endoplasmic reticulum (ER)-resident protein that confers cellular protection as an anti-apoptotic protein by limiting multiple stress-inducing pathways surrounding the endoplasmic reticulum and mitochondria (PubMed:21075086, PubMed:21068390). In
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF01027 Bax1-I 24 → 225 Inhibitor of apoptosis-promoting Bax1 Family
Tissue specificity TISSUE SPECIFICITY: Highly abundant in testis. {ECO:0000269|PubMed:8530040}.
Sequence
Sequence length 237
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
KEGG Pathway
Pathogenic Escherichia coli infection