TM4SF18 (transmembrane 4 L six family member 18)

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Gene miRNA Gene ontology Other IDs Protein Associated diseases Related genes Diseases linked via similar genes

Gene

• Entrez ID: 116441
• Gene name: Transmembrane 4 L six family member 18
• Gene symbol: TM4SF18
• Synonyms (NCBI Gene): L6D
• Chromosome: 3
• Chromosome location: 3q25.1

miRNA Show/Hide all (92)

miRTarBase ID	miRNA	Experiments	Reference
MIRT714638	hsa-miR-6861-3p	HITS-CLIP	19536157
MIRT714637	hsa-miR-492	HITS-CLIP	19536157
MIRT714636	hsa-miR-659-5p	HITS-CLIP	19536157
MIRT714635	hsa-miR-4800-5p	HITS-CLIP	19536157
MIRT714634	hsa-miR-520a-5p	HITS-CLIP	19536157
MIRT714633	hsa-miR-525-5p	HITS-CLIP	19536157
MIRT714632	hsa-miR-4535	HITS-CLIP	19536157
MIRT714631	hsa-miR-3180-5p	HITS-CLIP	19536157
MIRT714638	hsa-miR-6861-3p	HITS-CLIP	19536157
MIRT714637	hsa-miR-492	HITS-CLIP	19536157
MIRT714636	hsa-miR-659-5p	HITS-CLIP	19536157
MIRT714635	hsa-miR-4800-5p	HITS-CLIP	19536157
MIRT714634	hsa-miR-520a-5p	HITS-CLIP	19536157
MIRT714633	hsa-miR-525-5p	HITS-CLIP	19536157
MIRT714632	hsa-miR-4535	HITS-CLIP	19536157
MIRT714631	hsa-miR-3180-5p	HITS-CLIP	19536157
MIRT1427242	hsa-miR-1179	CLIP-seq
MIRT1427243	hsa-miR-1256	CLIP-seq
MIRT1427244	hsa-miR-1279	CLIP-seq
MIRT1427245	hsa-miR-150	CLIP-seq
MIRT1427246	hsa-miR-203	CLIP-seq
MIRT1427247	hsa-miR-299-5p	CLIP-seq
MIRT1427248	hsa-miR-3140-3p	CLIP-seq
MIRT1427249	hsa-miR-3171	CLIP-seq
MIRT1427250	hsa-miR-3663-5p	CLIP-seq
MIRT1427251	hsa-miR-3691-3p	CLIP-seq
MIRT1427252	hsa-miR-4642	CLIP-seq
MIRT1427253	hsa-miR-4713-5p	CLIP-seq
MIRT1427254	hsa-miR-4724-5p	CLIP-seq
MIRT1427255	hsa-miR-4787-5p	CLIP-seq
MIRT1427256	hsa-miR-490-3p	CLIP-seq
MIRT1427257	hsa-miR-532-3p	CLIP-seq
MIRT1427258	hsa-miR-629	CLIP-seq
MIRT1427259	hsa-miR-649	CLIP-seq
MIRT1427260	hsa-miR-664	CLIP-seq
MIRT1427261	hsa-miR-9	CLIP-seq
MIRT1427245	hsa-miR-150	CLIP-seq
MIRT1427246	hsa-miR-203	CLIP-seq
MIRT1427247	hsa-miR-299-5p	CLIP-seq
MIRT1427250	hsa-miR-3663-5p	CLIP-seq
MIRT1427251	hsa-miR-3691-3p	CLIP-seq
MIRT1427253	hsa-miR-4713-5p	CLIP-seq
MIRT1427254	hsa-miR-4724-5p	CLIP-seq
MIRT1427255	hsa-miR-4787-5p	CLIP-seq
MIRT1427257	hsa-miR-532-3p	CLIP-seq
MIRT1427258	hsa-miR-629	CLIP-seq
MIRT1427245	hsa-miR-150	CLIP-seq
MIRT1427250	hsa-miR-3663-5p	CLIP-seq
MIRT1427251	hsa-miR-3691-3p	CLIP-seq
MIRT1427253	hsa-miR-4713-5p	CLIP-seq
MIRT1427256	hsa-miR-490-3p	CLIP-seq
MIRT1427257	hsa-miR-532-3p	CLIP-seq
MIRT1921320	hsa-miR-619	CLIP-seq
MIRT1427259	hsa-miR-649	CLIP-seq
MIRT1427246	hsa-miR-203	CLIP-seq
MIRT1427247	hsa-miR-299-5p	CLIP-seq
MIRT1427254	hsa-miR-4724-5p	CLIP-seq
MIRT1427255	hsa-miR-4787-5p	CLIP-seq
MIRT1427256	hsa-miR-490-3p	CLIP-seq
MIRT2127976	hsa-miR-607	CLIP-seq
MIRT1427258	hsa-miR-629	CLIP-seq
MIRT2349634	hsa-miR-1178	CLIP-seq
MIRT1427245	hsa-miR-150	CLIP-seq
MIRT1427250	hsa-miR-3663-5p	CLIP-seq
MIRT1427251	hsa-miR-3691-3p	CLIP-seq
MIRT2349635	hsa-miR-410	CLIP-seq
MIRT2349636	hsa-miR-451b	CLIP-seq
MIRT1427253	hsa-miR-4713-5p	CLIP-seq
MIRT2349637	hsa-miR-4762-3p	CLIP-seq
MIRT2349638	hsa-miR-4766-5p	CLIP-seq
MIRT1427257	hsa-miR-532-3p	CLIP-seq
MIRT2349639	hsa-miR-548l	CLIP-seq
MIRT2349640	hsa-miR-622	CLIP-seq
MIRT1427245	hsa-miR-150	CLIP-seq
MIRT2395876	hsa-miR-224	CLIP-seq
MIRT2395877	hsa-miR-3127-5p	CLIP-seq
MIRT2395878	hsa-miR-3145-5p	CLIP-seq
MIRT2395879	hsa-miR-323b-3p	CLIP-seq
MIRT1427250	hsa-miR-3663-5p	CLIP-seq
MIRT1427251	hsa-miR-3691-3p	CLIP-seq
MIRT2395880	hsa-miR-4423-3p	CLIP-seq
MIRT2395881	hsa-miR-4645-5p	CLIP-seq
MIRT2395882	hsa-miR-4673	CLIP-seq
MIRT1427253	hsa-miR-4713-5p	CLIP-seq
MIRT2395883	hsa-miR-508-5p	CLIP-seq
MIRT1427257	hsa-miR-532-3p	CLIP-seq
MIRT2461524	hsa-miR-4291	CLIP-seq
MIRT2461525	hsa-miR-545	CLIP-seq
MIRT2643173	hsa-miR-3646	CLIP-seq
MIRT2643174	hsa-miR-4729	CLIP-seq
MIRT2643175	hsa-miR-579	CLIP-seq
MIRT2643175	hsa-miR-579	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005515	Function	Protein binding	IPI	32296183
GO:0016020	Component	Membrane	IBA
GO:0016020	Component	Membrane	IEA

Other IDs

• MIM: HGNC
• HGNC: N/A
• e!Ensembl: HGNC

Protein

• UniProt ID: Q96CE8
• Protein name: Transmembrane 4 L6 family member 18
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF05805	L6_membrane	1 → 193	L6 membrane protein	Family

• Sequence:

  MGSRKCGGCLSCLLIPLALWSIIVNILLYFPNGQTSYASSNKLTNYVWYFEGICFSGIMM
  LIVTTVLLVLENNNNYKCCQSENCSKKYVTLLSIIFSSLGIAFSGYCLVISALGLVQGPY
  CRTLDGWEYAFEGTAGRFLTDSSIWIQCLEPAHVVEWNIILFSILITLSGLQVIICLIRV
  VMQLSKILCGSYSVIFQPGII

• Sequence length: 201

Associated diseases

Evidence Score:

• ★☆☆☆☆  Gene-disease association found in Text Mining only
• ★★☆☆☆  Found in Text Mining and Unknown/Other Associations
• ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources
• ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
• ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Unknown / Other Associations
Phenotype Name	Clinical Significance	Source	Reference	Evidence Score
LUNG CARCINOMA	—	GWAS catalog	40829600	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
SCOLIOSIS	—	GWAS catalog	30019117	★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Associations from Text Mining Show/Hide Text Mining Associations (6)
Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Androgen Insensitivity Syndrome	Androgen insensitivity syndrome	Pubtator	31671693	Associate	★☆☆☆☆ Found in Text Mining only
ANOPHTHALMIA AND PULMONARY HYPOPLASIA	Syndromic microphthalmia	BEFREE	30897168		★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of pancreas	Pancreatic cancer	BEFREE	30897168		★☆☆☆☆ Found in Text Mining only
Neoplasms	Neoplasms	BEFREE	30897168		★☆☆☆☆ Found in Text Mining only
Pancreatic carcinoma	Pancreatic carcinoma	BEFREE	30897168		★☆☆☆☆ Found in Text Mining only
Stomach Neoplasms	Stomach neoplasms	Pubtator	36209368	Stimulate	★☆☆☆☆ Found in Text Mining only

Related Genes

No strongly related genes found yet for TM4SF18.

Diseases Linked via Similar Genes

No additional diseases found yet through genes similar to TM4SF18.