TLDC2 (TBC/LysM-associated domain containing 2)

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Gene Gene information from NCBI Gene database.
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Entrez ID 140711
Gene name TBC/LysM-associated domain containing 2
Gene symbol TLDC2
Synonyms (NCBI Gene)
C20orf118
Chromosome 20
Chromosome location 20q11.23
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
2
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GO ID Ontology Definition Evidence Reference
GO:0005634 Component Nucleus IBA
GO:0006979 Process Response to oxidative stress IBA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
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MIM HGNC e!Ensembl
HGNC N/A HGNC
Protein Protein information from UniProt database.
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UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
A0PJX2
Protein name TLD domain-containing protein 2 (TBC/LysM-associated domain-containing protein 2)
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF07534 TLD 79 → 215 TLD Domain
Sequence 
MRGLRWRYTRLPSQVEDTLSGEEGNEEEEEEEAAPDPAAAPEDPTVPQLTEASQVLSASE
IRQLSFHFPPRVTGHPWSLVFCTSRDGFSLQSLYRRMEGCSGPVLLVLRDQDGQIFGAFS
SSAIRLSKGFYGTGETFLFSFSPQLKVFKWTGSNSFFVKGDLDSLMMGSGSGRFGLWLDG
DLFRGGSSPCPTFNNEVLARQEQFCIQELEAWLLS
Sequence length 215
Interactions View interactions
Associated diseases Disease associations from ClinVar (causal & non-causal) and other databases (OMIM, Orphanet, GWAS, etc.).
2
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Evidence Score: ★☆☆☆☆  Gene-disease association found in Text Mining only ★★☆☆☆  Found in Text Mining and Unknown/Other Associations ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
Phenotype Name Clinical Significance Source Reference Evidence Score
CHILBLAIN LUPUS 2 — Disgenet —
★★★★★
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
LUNG ADENOCARCINOMA — GWAS catalog 29924316
★★★★★
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
Associations from Text Mining Disease associations identified through text mining
Disease Name Disease (Merged) Source PMID Relationship Type Evidence Score
Leukemia Myeloid Acute Myeloid leukemia Pubtator 36689724 Associate
★★★★★
★☆☆☆☆
Found in Text Mining only

No strongly related genes found yet for TLDC2.

No additional diseases found yet through genes similar to TLDC2.