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Gene Gene information from NCBI Gene database.
Entrez ID 93643
Gene name Tight junction associated protein 1
Gene symbol TJAP1
Synonyms (NCBI Gene)
PILTTJP4
Chromosome 6
Chromosome location 6p21.1
Summary This gene encodes a tight junction-associated protein. Incorporation of the encoded protein into tight junctions occurs at a late stage of formation of the junctions. The encoded protein localizes to the Golgi and may function in vesicle trafficking. Alte
miRNA miRNA information provided by mirtarbase database.
322 Show/Hide all (322)
miRTarBase ID miRNA Experiments Reference
MIRT007167 hsa-miR-132-3p Luciferase reporter assay 23184980
MIRT044523 hsa-miR-320a CLASH 23622248
MIRT043376 hsa-miR-331-3p CLASH 23622248
MIRT037611 hsa-miR-744-5p CLASH 23622248
MIRT007167 hsa-miR-132-3p PAR-CLIP 21572407
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
13 Show/Hide all (13)
GO ID Ontology Definition Evidence Reference
GO:0005515 Function Protein binding IPI 32296183
GO:0005737 Component Cytoplasm IEA
GO:0005768 Component Endosome IEA
GO:0005794 Component Golgi apparatus IDA
GO:0005794 Component Golgi apparatus IEA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
612658 17949 ENSG00000137221
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q5JTD0
Protein name Tight junction-associated protein 1 (Protein incorporated later into tight junctions) (Tight junction protein 4)
Protein function Plays a role in regulating the structure of the Golgi apparatus.
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF15453 Pilt 274 → 469 Protein incorporated later into Tight Junctions Family
PF15453 Pilt 466 → 556 Protein incorporated later into Tight Junctions Family
Tissue specificity TISSUE SPECIFICITY: Ubiquitously expressed. {ECO:0000269|PubMed:11602598}.
Sequence
MTSAAPAKKPYRKAPPEHRELRLEIPGSRLEQEEPLTDAERMKLLQEENEELRRRLASAT
RRTEALERELEIGQDCLELELGQSREELDKFKDKFRRLQNSYTASQRTNQELEDKLHTLA
SLSHSWIFAIKKAEMDRKTLDWEIVELTNKLLDAKNTINKLEELNERYRLDCNLAVQLLK
CNKSHFRNHKFADLPCELQDMVRKHLHSGQEAASPGPAPSLAPGAVVPTSVIARVLEKPE
SLLLNSAQSGSAGRPLAEDVFVHVDMSEGVPGDPASPPAPGSPTPQPNGECHSLGTARGS
PEEELPLPAFEKLNPYPTPSPPHPLYPGRRVIEFSEDKVRIPRNSPLPNCTYATRQAISL
SLVEEGSERARPSPVPSTPASAQASPHHQPSPAPLTLSAPASSASSEEDLLVSWQRAFVD
RTPPPAAVAQRTAFGRDALPELQRHFAHSPADRDEVVQAPSARPE
ESELLLPTEPDSGFP
REEEELNLPISPEEERQSLLPINRGTEEGPGTSHTEGRAWPLPSSSRPQRSPKRMGVHHL
HRKDSLTQAQEQGNLL
N
Sequence length 557
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
KEGG Pathway
Tight junction