TIMM17B (translocase of inner mitochondrial membrane 17B)

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Gene miRNA Gene ontology Other IDs Protein Pathways Diseases linked via similar genes

Gene

• Entrez ID: 10245
• Gene name: Translocase of inner mitochondrial membrane 17B
• Gene symbol: TIMM17B
• Synonyms (NCBI Gene): DXS9822, JM3, TIM17B
• Chromosome: X
• Chromosome location: Xp11.23
• Summary: This gene encodes a multipass transmembrane protein that forms an integral component of the mitochondrial translocase TIM23 complex. This complex facilitates the transport of mitochondrial proteins from the cytosol across the mitochondrial inner membrane

miRNA Show/Hide all (197)

miRTarBase ID	miRNA	Experiments	Reference
MIRT027417	hsa-miR-98-5p	Microarray	19088304
MIRT052791	hsa-miR-3176	CLASH	23622248
MIRT1424957	hsa-miR-1227	CLIP-seq
MIRT1424958	hsa-miR-1323	CLIP-seq
MIRT1424959	hsa-miR-146a	CLIP-seq
MIRT1424960	hsa-miR-146b-5p	CLIP-seq
MIRT1424961	hsa-miR-28-5p	CLIP-seq
MIRT1424962	hsa-miR-3064-3p	CLIP-seq
MIRT1424963	hsa-miR-3139	CLIP-seq
MIRT1424964	hsa-miR-342-5p	CLIP-seq
MIRT1424965	hsa-miR-4487	CLIP-seq
MIRT1424966	hsa-miR-4523	CLIP-seq
MIRT1424967	hsa-miR-4651	CLIP-seq
MIRT1424968	hsa-miR-4664-5p	CLIP-seq
MIRT1424969	hsa-miR-4728-5p	CLIP-seq
MIRT1424970	hsa-miR-4731-5p	CLIP-seq
MIRT1424971	hsa-miR-542-5p	CLIP-seq
MIRT1424972	hsa-miR-548o	CLIP-seq
MIRT1424973	hsa-miR-589	CLIP-seq
MIRT1424974	hsa-miR-607	CLIP-seq
MIRT1424975	hsa-miR-608	CLIP-seq
MIRT1424976	hsa-miR-708	CLIP-seq
MIRT1424977	hsa-let-7a	CLIP-seq
MIRT1424978	hsa-let-7b	CLIP-seq
MIRT1424979	hsa-let-7c	CLIP-seq
MIRT1424980	hsa-let-7d	CLIP-seq
MIRT1424981	hsa-let-7e	CLIP-seq
MIRT1424982	hsa-let-7f	CLIP-seq
MIRT1424983	hsa-let-7g	CLIP-seq
MIRT1424984	hsa-let-7i	CLIP-seq
MIRT1424957	hsa-miR-1227	CLIP-seq
MIRT1424958	hsa-miR-1323	CLIP-seq
MIRT1424959	hsa-miR-146a	CLIP-seq
MIRT1424960	hsa-miR-146b-5p	CLIP-seq
MIRT1424961	hsa-miR-28-5p	CLIP-seq
MIRT1424962	hsa-miR-3064-3p	CLIP-seq
MIRT1424963	hsa-miR-3139	CLIP-seq
MIRT1424985	hsa-miR-3192	CLIP-seq
MIRT1424986	hsa-miR-3194-5p	CLIP-seq
MIRT1424964	hsa-miR-342-5p	CLIP-seq
MIRT1424987	hsa-miR-3529	CLIP-seq
MIRT1424988	hsa-miR-3607-5p	CLIP-seq
MIRT1424989	hsa-miR-379	CLIP-seq
MIRT1424990	hsa-miR-3927	CLIP-seq
MIRT1424991	hsa-miR-4287	CLIP-seq
MIRT1424992	hsa-miR-4290	CLIP-seq
MIRT1424993	hsa-miR-4300	CLIP-seq
MIRT1424994	hsa-miR-4458	CLIP-seq
MIRT1424965	hsa-miR-4487	CLIP-seq
MIRT1424995	hsa-miR-4500	CLIP-seq
MIRT1424967	hsa-miR-4651	CLIP-seq
MIRT1424968	hsa-miR-4664-5p	CLIP-seq
MIRT1424996	hsa-miR-4666-5p	CLIP-seq
MIRT1424997	hsa-miR-4685-3p	CLIP-seq
MIRT1424998	hsa-miR-4687-5p	CLIP-seq
MIRT1424970	hsa-miR-4731-5p	CLIP-seq
MIRT1424971	hsa-miR-542-5p	CLIP-seq
MIRT1424972	hsa-miR-548o	CLIP-seq
MIRT1424999	hsa-miR-582-3p	CLIP-seq
MIRT1424973	hsa-miR-589	CLIP-seq
MIRT1424974	hsa-miR-607	CLIP-seq
MIRT1424975	hsa-miR-608	CLIP-seq
MIRT1424976	hsa-miR-708	CLIP-seq
MIRT1425000	hsa-miR-920	CLIP-seq
MIRT1425001	hsa-miR-98	CLIP-seq
MIRT2127327	hsa-miR-1207-3p	CLIP-seq
MIRT2127328	hsa-miR-3127-5p	CLIP-seq
MIRT2127329	hsa-miR-3189-5p	CLIP-seq
MIRT2127330	hsa-miR-3199	CLIP-seq
MIRT1424964	hsa-miR-342-5p	CLIP-seq
MIRT2127331	hsa-miR-3620	CLIP-seq
MIRT2127332	hsa-miR-3918	CLIP-seq
MIRT2127333	hsa-miR-4292	CLIP-seq
MIRT2127334	hsa-miR-4436b-3p	CLIP-seq
MIRT1424967	hsa-miR-4651	CLIP-seq
MIRT1424968	hsa-miR-4664-5p	CLIP-seq
MIRT1424970	hsa-miR-4731-5p	CLIP-seq
MIRT2127335	hsa-miR-4758-3p	CLIP-seq
MIRT1424999	hsa-miR-582-3p	CLIP-seq
MIRT1424975	hsa-miR-608	CLIP-seq
MIRT1424977	hsa-let-7a	CLIP-seq
MIRT1424978	hsa-let-7b	CLIP-seq
MIRT1424979	hsa-let-7c	CLIP-seq
MIRT1424980	hsa-let-7d	CLIP-seq
MIRT1424981	hsa-let-7e	CLIP-seq
MIRT1424982	hsa-let-7f	CLIP-seq
MIRT1424983	hsa-let-7g	CLIP-seq
MIRT1424984	hsa-let-7i	CLIP-seq
MIRT2127327	hsa-miR-1207-3p	CLIP-seq
MIRT1424957	hsa-miR-1227	CLIP-seq
MIRT2349142	hsa-miR-125a-5p	CLIP-seq
MIRT2349143	hsa-miR-125b	CLIP-seq
MIRT2349144	hsa-miR-1321	CLIP-seq
MIRT1424959	hsa-miR-146a	CLIP-seq
MIRT2349145	hsa-miR-146b-3p	CLIP-seq
MIRT1424960	hsa-miR-146b-5p	CLIP-seq
MIRT1424961	hsa-miR-28-5p	CLIP-seq
MIRT1424962	hsa-miR-3064-3p	CLIP-seq
MIRT2127328	hsa-miR-3127-5p	CLIP-seq
MIRT1424963	hsa-miR-3139	CLIP-seq
MIRT2349146	hsa-miR-3151	CLIP-seq
MIRT2349147	hsa-miR-3162-5p	CLIP-seq
MIRT2349148	hsa-miR-3173-5p	CLIP-seq
MIRT1424985	hsa-miR-3192	CLIP-seq
MIRT1424986	hsa-miR-3194-5p	CLIP-seq
MIRT1424964	hsa-miR-342-5p	CLIP-seq
MIRT2349149	hsa-miR-34a	CLIP-seq
MIRT2349150	hsa-miR-34c-5p	CLIP-seq
MIRT1424987	hsa-miR-3529	CLIP-seq
MIRT1424988	hsa-miR-3607-5p	CLIP-seq
MIRT2349151	hsa-miR-3659	CLIP-seq
MIRT1424989	hsa-miR-379	CLIP-seq
MIRT2127332	hsa-miR-3918	CLIP-seq
MIRT1424990	hsa-miR-3927	CLIP-seq
MIRT2349152	hsa-miR-4283	CLIP-seq
MIRT1424991	hsa-miR-4287	CLIP-seq
MIRT1424992	hsa-miR-4290	CLIP-seq
MIRT1424993	hsa-miR-4300	CLIP-seq
MIRT2349153	hsa-miR-4319	CLIP-seq
MIRT2127334	hsa-miR-4436b-3p	CLIP-seq
MIRT2349154	hsa-miR-4447	CLIP-seq
MIRT1424994	hsa-miR-4458	CLIP-seq
MIRT2349155	hsa-miR-4472	CLIP-seq
MIRT1424965	hsa-miR-4487	CLIP-seq
MIRT2349156	hsa-miR-4489	CLIP-seq
MIRT2349157	hsa-miR-4492	CLIP-seq
MIRT2349158	hsa-miR-4498	CLIP-seq
MIRT2349159	hsa-miR-449a	CLIP-seq
MIRT2349160	hsa-miR-449b	CLIP-seq
MIRT1424995	hsa-miR-4500	CLIP-seq
MIRT2349161	hsa-miR-4505	CLIP-seq
MIRT1424966	hsa-miR-4523	CLIP-seq
MIRT1424967	hsa-miR-4651	CLIP-seq
MIRT2349162	hsa-miR-4658	CLIP-seq
MIRT1424968	hsa-miR-4664-5p	CLIP-seq
MIRT1424996	hsa-miR-4666-5p	CLIP-seq
MIRT1424997	hsa-miR-4685-3p	CLIP-seq
MIRT1424998	hsa-miR-4687-5p	CLIP-seq
MIRT1424969	hsa-miR-4728-5p	CLIP-seq
MIRT1424970	hsa-miR-4731-5p	CLIP-seq
MIRT2349163	hsa-miR-4739	CLIP-seq
MIRT2349164	hsa-miR-4756-5p	CLIP-seq
MIRT2349165	hsa-miR-491-5p	CLIP-seq
MIRT1424971	hsa-miR-542-5p	CLIP-seq
MIRT2349166	hsa-miR-562	CLIP-seq
MIRT2349167	hsa-miR-574-5p	CLIP-seq
MIRT1424999	hsa-miR-582-3p	CLIP-seq
MIRT1424973	hsa-miR-589	CLIP-seq
MIRT1424975	hsa-miR-608	CLIP-seq
MIRT1424976	hsa-miR-708	CLIP-seq
MIRT2349168	hsa-miR-762	CLIP-seq
MIRT2349169	hsa-miR-874	CLIP-seq
MIRT1425000	hsa-miR-920	CLIP-seq
MIRT1425001	hsa-miR-98	CLIP-seq
MIRT1424957	hsa-miR-1227	CLIP-seq
MIRT1424961	hsa-miR-28-5p	CLIP-seq
MIRT1424962	hsa-miR-3064-3p	CLIP-seq
MIRT1424963	hsa-miR-3139	CLIP-seq
MIRT1424964	hsa-miR-342-5p	CLIP-seq
MIRT1424965	hsa-miR-4487	CLIP-seq
MIRT1424967	hsa-miR-4651	CLIP-seq
MIRT1424968	hsa-miR-4664-5p	CLIP-seq
MIRT1424970	hsa-miR-4731-5p	CLIP-seq
MIRT1424975	hsa-miR-608	CLIP-seq
MIRT1424976	hsa-miR-708	CLIP-seq
MIRT2127327	hsa-miR-1207-3p	CLIP-seq
MIRT2349144	hsa-miR-1321	CLIP-seq
MIRT2642366	hsa-miR-1915	CLIP-seq
MIRT2127328	hsa-miR-3127-5p	CLIP-seq
MIRT2349147	hsa-miR-3162-5p	CLIP-seq
MIRT2642367	hsa-miR-3183	CLIP-seq
MIRT2127329	hsa-miR-3189-5p	CLIP-seq
MIRT2127330	hsa-miR-3199	CLIP-seq
MIRT2642368	hsa-miR-326	CLIP-seq
MIRT2642369	hsa-miR-330-5p	CLIP-seq
MIRT1424964	hsa-miR-342-5p	CLIP-seq
MIRT2127331	hsa-miR-3620	CLIP-seq
MIRT2127332	hsa-miR-3918	CLIP-seq
MIRT2127333	hsa-miR-4292	CLIP-seq
MIRT2127334	hsa-miR-4436b-3p	CLIP-seq
MIRT2642370	hsa-miR-4468	CLIP-seq
MIRT1424967	hsa-miR-4651	CLIP-seq
MIRT1424968	hsa-miR-4664-5p	CLIP-seq
MIRT2642371	hsa-miR-4685-5p	CLIP-seq
MIRT2642372	hsa-miR-4723-3p	CLIP-seq
MIRT2642373	hsa-miR-4726-3p	CLIP-seq
MIRT1424970	hsa-miR-4731-5p	CLIP-seq
MIRT2349163	hsa-miR-4739	CLIP-seq
MIRT2349164	hsa-miR-4756-5p	CLIP-seq
MIRT2127335	hsa-miR-4758-3p	CLIP-seq
MIRT2642374	hsa-miR-516b	CLIP-seq
MIRT1424975	hsa-miR-608	CLIP-seq
MIRT2127329	hsa-miR-3189-5p	CLIP-seq
MIRT2127330	hsa-miR-3199	CLIP-seq
MIRT2127331	hsa-miR-3620	CLIP-seq
MIRT2127333	hsa-miR-4292	CLIP-seq
MIRT2127335	hsa-miR-4758-3p	CLIP-seq

Gene ontology (GO) Show/Hide all (18)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005515	Function	Protein binding	IPI	23263864, 32296183, 32814053
GO:0005739	Component	Mitochondrion	HTP	34800366
GO:0005739	Component	Mitochondrion	IEA
GO:0005743	Component	Mitochondrial inner membrane	IDA	10339406, 20053669
GO:0005743	Component	Mitochondrial inner membrane	IEA
GO:0005743	Component	Mitochondrial inner membrane	NAS	10339406
GO:0005744	Component	TIM23 mitochondrial import inner membrane translocase complex	IBA
GO:0005744	Component	TIM23 mitochondrial import inner membrane translocase complex	IDA	10339406, 30598479
GO:0005744	Component	TIM23 mitochondrial import inner membrane translocase complex	IEA
GO:0005744	Component	TIM23 mitochondrial import inner membrane translocase complex	NAS	10339406
GO:0006626	Process	Protein targeting to mitochondrion	TAS	10339406
GO:0006886	Process	Intracellular protein transport	NAS	10339406
GO:0008320	Function	Protein transmembrane transporter activity	IBA
GO:0008320	Function	Protein transmembrane transporter activity	IEA
GO:0015031	Process	Protein transport	IEA
GO:0016020	Component	Membrane	IEA
GO:0030150	Process	Protein import into mitochondrial matrix	IBA
GO:0030150	Process	Protein import into mitochondrial matrix	IEA

Other IDs

• MIM: 300249
• HGNC: 17310
• e!Ensembl: ENSG00000126768

Protein

• UniProt ID: O60830
• Protein name: Mitochondrial import inner membrane translocase subunit Tim17-B
• Protein function: Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF02466	Tim17	13 → 123		Family

• Tissue specificity: TISSUE SPECIFICITY: Expression is abundant in heart and skeletal muscle, intermediate in brain, and weak in pancreas, placenta, kidney and liver.
• Sequence:

  MEEYAREPCPWRIVDDCGGAFTMGVIGGGVFQAIKGFRNAPVGIRHRLRGSANAVRIRAP
  QIGGSFAVWGGLFSTIDCGLVRLRGKEDPWNSITSGALTGAVLAARSGPLAMVGSAMMGG
  ILLALIEGVGILLTRYTAQQFRNAPPFLEDPSQLPPKDGTPAPGYPSYQQYH

• Sequence length: 172

Pathways

Reactome Pathway:

Mitochondrial protein import

Related Genes

No strongly related genes found yet for TIMM17B.

Diseases Linked via Similar Genes

No additional diseases found yet through genes similar to TIMM17B.