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Gene Gene information from NCBI Gene database.
Entrez ID 168451
Gene name THAP domain containing 5
Gene symbol THAP5
Synonyms (NCBI Gene)
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Chromosome 7
Chromosome location 7q31.1
miRNA miRNA information provided by mirtarbase database.
579 Show/Hide all (579)
miRTarBase ID miRNA Experiments Reference
MIRT674311 hsa-miR-6815-5p HITS-CLIP 23824327
MIRT674310 hsa-miR-6865-5p HITS-CLIP 23824327
MIRT674309 hsa-miR-383-3p HITS-CLIP 23824327
MIRT674308 hsa-miR-7106-5p HITS-CLIP 23824327
MIRT674307 hsa-miR-149-3p HITS-CLIP 23824327
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
11 Show/Hide all (11)
GO ID Ontology Definition Evidence Reference
GO:0000122 Process Negative regulation of transcription by RNA polymerase II IDA 21110952
GO:0000785 Component Chromatin IDA 21110952
GO:0002020 Function Protease binding IPI 19502560
GO:0003677 Function DNA binding IEA
GO:0005634 Component Nucleus IBA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
612534 23188 ENSG00000177683
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q7Z6K1
Protein name THAP domain-containing protein 5
Protein function Has sequence-specific DNA-binding activity and can function as transcriptional repressor (in vitro) (PubMed:21110952). May be a regulator of cell cycle: THAP5 overexpression in human cell lines causes cell cycle arrest at G2/M phase (PubMed:1950
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF05485 THAP 5 → 84 THAP domain Domain
Tissue specificity TISSUE SPECIFICITY: Detected in heart (PubMed:19502560, PubMed:21195082). Detected in brain and muscle (at protein level) (PubMed:19502560). Highly expressed in the heart. Also found in brain and skeletal muscle (PubMed:19502560, PubMed:21195082). {ECO:00
Sequence
MPRYCAAICCKNRRGRNNKDRKLSFYPFPLHDKERLEKWLKNMKRDSWVPSKYQFLCSDH
FTPDSLDIRWGIRYLKQTAVPTIF
SLPEDNQGKDPSKKKSQKKNLEDEKEVCPKAKSEES
FVLNETKKNIVNTDVPHQHPELLHSSSLVKPPAPKTGSIQNNMLTLNLVKQHTGKPESTL
ETSVNQDTGRGGFHTCFENLNSTTITLTTSNSESIHQSLETQEVLEVTTSHLANPNFTSN
SMEIKSAQENPFLFSTINQTVEELNTNKESVIAIFVPAENSKPSVNSFISAQKETTEMED
TDIEDSLYKDVDYGTEVLQIEHSYCRQDINKEHLWQKVSKLHSKITLLELKEQQTLGRLK
SLEALIRQLKQENWLSEENVKIIENHFTTYEVTMI
Sequence length 395
Interactions View interactions