TBC1D14 (TBC1 domain family member 14)
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Gene
Gene information from NCBI Gene database.
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| Entrez ID | 57533 |
| Gene name | TBC1 domain family member 14 |
| Gene symbol | TBC1D14 |
| Synonyms (NCBI Gene) |
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| Chromosome | 4 |
| Chromosome location | 4p16.1 |
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miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
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Other IDs
Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
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Protein
Protein information from UniProt database.
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UniProt ID
Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
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Q9P2M4 | ||||||||||
| Protein name | TBC1 domain family member 14 | ||||||||||
| Protein function | Plays a role in the regulation of starvation-induced autophagosome formation (PubMed:22613832). Together with the TRAPPIII complex, regulates a constitutive trafficking step from peripheral recycling endosomes to the early Golgi, maintaining the | ||||||||||
| PDB | 2QQ8 | ||||||||||
| Family and domains |
Pfam
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| Sequence |
MTDGKLSTSTNGVAFMGILDGRPGNPLQNLQHVNLKAPRLLSAPEYGPKLKLRALEDRHS |
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| Sequence length | 693 | ||||||||||
| Interactions | View interactions | ||||||||||
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Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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Associated diseases
Disease associations from ClinVar (causal & non-causal) and other databases (OMIM, Orphanet, GWAS, etc.).
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Evidence Score:
★☆☆☆☆ Gene-disease association found in Text Mining only
★★☆☆☆ Found in Text Mining and Unknown/Other Associations
★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources
★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)
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Related Genes
Genes most often co-reported with TBC1D14 across shared curated disease and pathway associations.
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Diseases Linked via Similar Genes
Diseases curated for genes most similar to TBC1D14 (see Related Genes above), that are NOT already directly curated for TBC1D14 itself -- a lead worth checking, not a confirmed association.
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