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Gene Gene information from NCBI Gene database.
Entrez ID 6882
Gene name TATA-box binding protein associated factor 11
Gene symbol TAF11
Synonyms (NCBI Gene)
MGC:15243PRO2134TAF2ITAFII28
Chromosome 6
Chromosome location 6p21.31
Summary Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly,
miRNA miRNA information provided by mirtarbase database.
265 Show/Hide all (265)
miRTarBase ID miRNA Experiments Reference
MIRT037327 hsa-miR-877-5p CLASH 23622248
MIRT542662 hsa-miR-508-5p PAR-CLIP 21572407
MIRT542663 hsa-miR-6849-3p PAR-CLIP 21572407
MIRT542661 hsa-miR-766-3p PAR-CLIP 21572407
MIRT542660 hsa-miR-4793-3p PAR-CLIP 21572407
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
29 Show/Hide all (29)
GO ID Ontology Definition Evidence Reference
GO:0003713 Function Transcription coactivator activity IDA 8670810
GO:0005515 Function Protein binding IPI 7729427, 9045704, 9695952, 25416956, 32296183
GO:0005634 Component Nucleus EXP 23332750
GO:0005634 Component Nucleus IEA
GO:0005634 Component Nucleus ISS
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
600772 11544 ENSG00000064995
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q15544
Protein name Transcription initiation factor TFIID subunit 11 (TFIID subunit p30-beta) (Transcription initiation factor TFIID 28 kDa subunit) (TAF(II)28) (TAFII-28) (TAFII28)
Protein function The TFIID basal transcription factor complex plays a major role in the initiation of RNA polymerase II (Pol II)-dependent transcription (PubMed:33795473). TFIID recognizes and binds promoters with or without a TATA box via its subunit TBP, a TAT
PDB 1BH8 , 1BH9 , 6MZD , 6MZL , 7EDX , 7EG7 , 7EG8 , 7EG9 , 7EGA , 7EGB , 7EGC , 7EGD , 7EGE , 7EGF , 7EGI , 7EGJ , 7ENA , 7ENC , 8GXQ , 8GXS , 8WAK , 8WAL , 8WAN , 8WAO , 8WAP , 8WAQ , 8WAR , 8WAS
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF04719 TAFII28 108 → 193 hTAFII28-like protein conserved region Domain
Sequence
MDDAHESPSDKGGETGESDETAAVPGDPGATDTDGIPEETDGDADVDLKEAAAEEGELES
QDVSDLTTVEREDSSLLNPAAKKLKIDTKEKKEKKQKVDEDEIQKMQILVSSFSEEQLNR
YEMYRRSAFPKAAIKRLIQSITGTSVSQNVVIAMSGISKVFVGEVVEEALDVCEKWGEMP
PLQPKHMREAVRR
LKSKGQIPNSKHKKIIFF
Sequence length 211
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
KEGG Pathway Reactome Pathway
Basal transcription factors RNA Polymerase II Pre-transcription Events
  Regulation of TP53 Activity through Phosphorylation
  RNA polymerase II transcribes snRNA genes
  RNA Polymerase II Promoter Escape
  RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
  RNA Polymerase II Transcription Initiation
  RNA Polymerase II Transcription Initiation And Promoter Clearance