STK16 (serine/threonine kinase 16)

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Gene miRNA Gene ontology Other IDs Protein Related genes Diseases linked via similar genes

Gene

• Entrez ID: 8576
• Gene name: Serine/threonine kinase 16
• Gene symbol: STK16
• Synonyms (NCBI Gene): KRCT, MPSK, PKL12, PSK, TSF1, hPSK
• Chromosome: 2
• Chromosome location: 2q35

miRNA Show/Hide all (189)

miRTarBase ID	miRNA	Experiments	Reference
MIRT029140	hsa-miR-26b-5p	Microarray	19088304
MIRT044034	hsa-miR-365a-3p	CLASH	23622248
MIRT042840	hsa-miR-324-3p	CLASH	23622248
MIRT037413	hsa-miR-744-5p	CLASH	23622248
MIRT1397217	hsa-miR-1	CLIP-seq
MIRT1397218	hsa-miR-1224-5p	CLIP-seq
MIRT1397219	hsa-miR-1285	CLIP-seq
MIRT1397220	hsa-miR-1293	CLIP-seq
MIRT1397221	hsa-miR-1299	CLIP-seq
MIRT1397222	hsa-miR-132	CLIP-seq
MIRT1397223	hsa-miR-1321	CLIP-seq
MIRT1397224	hsa-miR-1343	CLIP-seq
MIRT1397225	hsa-miR-1587	CLIP-seq
MIRT1397226	hsa-miR-1910	CLIP-seq
MIRT1397227	hsa-miR-2052	CLIP-seq
MIRT1397228	hsa-miR-206	CLIP-seq
MIRT1397229	hsa-miR-212	CLIP-seq
MIRT1397230	hsa-miR-2964a-5p	CLIP-seq
MIRT1397231	hsa-miR-3064-3p	CLIP-seq
MIRT1397232	hsa-miR-3122	CLIP-seq
MIRT1397233	hsa-miR-3136-3p	CLIP-seq
MIRT1397234	hsa-miR-3151	CLIP-seq
MIRT1397235	hsa-miR-3155	CLIP-seq
MIRT1397236	hsa-miR-3155b	CLIP-seq
MIRT1397237	hsa-miR-3162-5p	CLIP-seq
MIRT1397238	hsa-miR-3187-5p	CLIP-seq
MIRT1397239	hsa-miR-328	CLIP-seq
MIRT1397240	hsa-miR-3673	CLIP-seq
MIRT1397241	hsa-miR-3689a-3p	CLIP-seq
MIRT1397242	hsa-miR-3689c	CLIP-seq
MIRT1397243	hsa-miR-370	CLIP-seq
MIRT1397244	hsa-miR-378g	CLIP-seq
MIRT1397245	hsa-miR-3913-5p	CLIP-seq
MIRT1397246	hsa-miR-421	CLIP-seq
MIRT1397247	hsa-miR-4268	CLIP-seq
MIRT1397248	hsa-miR-4318	CLIP-seq
MIRT1397249	hsa-miR-4447	CLIP-seq
MIRT1397250	hsa-miR-4472	CLIP-seq
MIRT1397251	hsa-miR-4483	CLIP-seq
MIRT1397252	hsa-miR-4492	CLIP-seq
MIRT1397253	hsa-miR-4498	CLIP-seq
MIRT1397254	hsa-miR-4506	CLIP-seq
MIRT1397255	hsa-miR-4656	CLIP-seq
MIRT1397256	hsa-miR-4668-3p	CLIP-seq
MIRT1397257	hsa-miR-4675	CLIP-seq
MIRT1397258	hsa-miR-4693-5p	CLIP-seq
MIRT1397259	hsa-miR-4708-3p	CLIP-seq
MIRT1397260	hsa-miR-4709-5p	CLIP-seq
MIRT1397261	hsa-miR-4716-5p	CLIP-seq
MIRT1397262	hsa-miR-4728-3p	CLIP-seq
MIRT1397263	hsa-miR-4739	CLIP-seq
MIRT1397264	hsa-miR-4741	CLIP-seq
MIRT1397265	hsa-miR-4751	CLIP-seq
MIRT1397266	hsa-miR-4756-5p	CLIP-seq
MIRT1397267	hsa-miR-484	CLIP-seq
MIRT1397268	hsa-miR-491-5p	CLIP-seq
MIRT1397269	hsa-miR-612	CLIP-seq
MIRT1397270	hsa-miR-613	CLIP-seq
MIRT1397271	hsa-miR-646	CLIP-seq
MIRT1397272	hsa-miR-671-5p	CLIP-seq
MIRT1397273	hsa-miR-762	CLIP-seq
MIRT1397274	hsa-miR-767-3p	CLIP-seq
MIRT1397275	hsa-miR-875-3p	CLIP-seq
MIRT1397276	hsa-miR-892a	CLIP-seq
MIRT1397222	hsa-miR-132	CLIP-seq
MIRT1397226	hsa-miR-1910	CLIP-seq
MIRT1397229	hsa-miR-212	CLIP-seq
MIRT1397243	hsa-miR-370	CLIP-seq
MIRT1397246	hsa-miR-421	CLIP-seq
MIRT1397260	hsa-miR-4709-5p	CLIP-seq
MIRT1397261	hsa-miR-4716-5p	CLIP-seq
MIRT2118980	hsa-miR-578	CLIP-seq
MIRT1397274	hsa-miR-767-3p	CLIP-seq
MIRT2341280	hsa-miR-1255a	CLIP-seq
MIRT2341281	hsa-miR-1255b	CLIP-seq
MIRT2341282	hsa-miR-1289	CLIP-seq
MIRT1397222	hsa-miR-132	CLIP-seq
MIRT1397226	hsa-miR-1910	CLIP-seq
MIRT1397229	hsa-miR-212	CLIP-seq
MIRT2341283	hsa-miR-3198	CLIP-seq
MIRT2341284	hsa-miR-3670	CLIP-seq
MIRT1397243	hsa-miR-370	CLIP-seq
MIRT1397246	hsa-miR-421	CLIP-seq
MIRT2341285	hsa-miR-4294	CLIP-seq
MIRT2341286	hsa-miR-4309	CLIP-seq
MIRT2341287	hsa-miR-4501	CLIP-seq
MIRT1397260	hsa-miR-4709-5p	CLIP-seq
MIRT1397261	hsa-miR-4716-5p	CLIP-seq
MIRT2341288	hsa-miR-587	CLIP-seq
MIRT1397274	hsa-miR-767-3p	CLIP-seq
MIRT2460674	hsa-miR-1287	CLIP-seq
MIRT2460675	hsa-miR-3135b	CLIP-seq
MIRT2460676	hsa-miR-4283	CLIP-seq
MIRT2460677	hsa-miR-4487	CLIP-seq
MIRT2460678	hsa-miR-4489	CLIP-seq
MIRT2460679	hsa-miR-4633-3p	CLIP-seq
MIRT1397257	hsa-miR-4675	CLIP-seq
MIRT2460680	hsa-miR-4731-5p	CLIP-seq
MIRT1397264	hsa-miR-4741	CLIP-seq
MIRT1397217	hsa-miR-1	CLIP-seq
MIRT2635157	hsa-miR-10a	CLIP-seq
MIRT2635158	hsa-miR-10b	CLIP-seq
MIRT2635159	hsa-miR-1193	CLIP-seq
MIRT2635160	hsa-miR-1202	CLIP-seq
MIRT2635161	hsa-miR-124	CLIP-seq
MIRT2460674	hsa-miR-1287	CLIP-seq
MIRT2635162	hsa-miR-1292	CLIP-seq
MIRT1397220	hsa-miR-1293	CLIP-seq
MIRT2635163	hsa-miR-153	CLIP-seq
MIRT1397228	hsa-miR-206	CLIP-seq
MIRT2635164	hsa-miR-2116	CLIP-seq
MIRT2635165	hsa-miR-3074-5p	CLIP-seq
MIRT2635166	hsa-miR-3124-3p	CLIP-seq
MIRT2635167	hsa-miR-3126-5p	CLIP-seq
MIRT2635168	hsa-miR-3130-3p	CLIP-seq
MIRT2460675	hsa-miR-3135b	CLIP-seq
MIRT1397240	hsa-miR-3673	CLIP-seq
MIRT2635169	hsa-miR-3690	CLIP-seq
MIRT1397243	hsa-miR-370	CLIP-seq
MIRT2635170	hsa-miR-3921	CLIP-seq
MIRT2635171	hsa-miR-3936	CLIP-seq
MIRT2635172	hsa-miR-3972	CLIP-seq
MIRT2635173	hsa-miR-4252	CLIP-seq
MIRT2635174	hsa-miR-4254	CLIP-seq
MIRT2635175	hsa-miR-4303	CLIP-seq
MIRT2635176	hsa-miR-431	CLIP-seq
MIRT2635177	hsa-miR-4419a	CLIP-seq
MIRT2635178	hsa-miR-4421	CLIP-seq
MIRT2635179	hsa-miR-4457	CLIP-seq
MIRT2635180	hsa-miR-4468	CLIP-seq
MIRT2635181	hsa-miR-4471	CLIP-seq
MIRT2635182	hsa-miR-448	CLIP-seq
MIRT1397251	hsa-miR-4483	CLIP-seq
MIRT1397254	hsa-miR-4506	CLIP-seq
MIRT2635183	hsa-miR-4510	CLIP-seq
MIRT2635184	hsa-miR-4529-5p	CLIP-seq
MIRT2460679	hsa-miR-4633-3p	CLIP-seq
MIRT2635185	hsa-miR-4640-3p	CLIP-seq
MIRT2635186	hsa-miR-4653-5p	CLIP-seq
MIRT2635187	hsa-miR-4677-5p	CLIP-seq
MIRT2635188	hsa-miR-4755-3p	CLIP-seq
MIRT2635189	hsa-miR-4786-5p	CLIP-seq
MIRT2635190	hsa-miR-506	CLIP-seq
MIRT2635191	hsa-miR-513c	CLIP-seq
MIRT2635192	hsa-miR-514b-5p	CLIP-seq
MIRT2635193	hsa-miR-516a-3p	CLIP-seq
MIRT2635194	hsa-miR-518a-5p	CLIP-seq
MIRT2635195	hsa-miR-527	CLIP-seq
MIRT1397270	hsa-miR-613	CLIP-seq
MIRT1397271	hsa-miR-646	CLIP-seq
MIRT2635196	hsa-miR-769-5p	CLIP-seq
MIRT2635197	hsa-miR-942	CLIP-seq
MIRT1397217	hsa-miR-1	CLIP-seq
MIRT2635157	hsa-miR-10a	CLIP-seq
MIRT2635158	hsa-miR-10b	CLIP-seq
MIRT2635159	hsa-miR-1193	CLIP-seq
MIRT2635161	hsa-miR-124	CLIP-seq
MIRT2635162	hsa-miR-1292	CLIP-seq
MIRT1397220	hsa-miR-1293	CLIP-seq
MIRT1397221	hsa-miR-1299	CLIP-seq
MIRT1397228	hsa-miR-206	CLIP-seq
MIRT2635164	hsa-miR-2116	CLIP-seq
MIRT2635165	hsa-miR-3074-5p	CLIP-seq
MIRT2635166	hsa-miR-3124-3p	CLIP-seq
MIRT2635167	hsa-miR-3126-5p	CLIP-seq
MIRT1397233	hsa-miR-3136-3p	CLIP-seq
MIRT1397235	hsa-miR-3155	CLIP-seq
MIRT1397236	hsa-miR-3155b	CLIP-seq
MIRT1397239	hsa-miR-328	CLIP-seq
MIRT1397240	hsa-miR-3673	CLIP-seq
MIRT2635169	hsa-miR-3690	CLIP-seq
MIRT1397243	hsa-miR-370	CLIP-seq
MIRT2635174	hsa-miR-4254	CLIP-seq
MIRT1397247	hsa-miR-4268	CLIP-seq
MIRT2635177	hsa-miR-4419a	CLIP-seq
MIRT2635179	hsa-miR-4457	CLIP-seq
MIRT2635181	hsa-miR-4471	CLIP-seq
MIRT1397251	hsa-miR-4483	CLIP-seq
MIRT1397254	hsa-miR-4506	CLIP-seq
MIRT2635183	hsa-miR-4510	CLIP-seq
MIRT2635184	hsa-miR-4529-5p	CLIP-seq
MIRT2635185	hsa-miR-4640-3p	CLIP-seq
MIRT2635187	hsa-miR-4677-5p	CLIP-seq
MIRT1397259	hsa-miR-4708-3p	CLIP-seq
MIRT1397267	hsa-miR-484	CLIP-seq
MIRT2635190	hsa-miR-506	CLIP-seq
MIRT1397270	hsa-miR-613	CLIP-seq
MIRT1397272	hsa-miR-671-5p	CLIP-seq
MIRT1397275	hsa-miR-875-3p	CLIP-seq

Gene ontology (GO) Show/Hide all (26)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000166	Function	Nucleotide binding	IEA
GO:0000978	Function	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IEA
GO:0004672	Function	Protein kinase activity	IEA
GO:0004674	Function	Protein serine/threonine kinase activity	IBA
GO:0004674	Function	Protein serine/threonine kinase activity	IEA
GO:0004713	Function	Protein tyrosine kinase activity	IEA
GO:0004715	Function	Non-membrane spanning protein tyrosine kinase activity	IEA
GO:0005515	Function	Protein binding	IPI	16189514, 18184589, 19060904, 25416956, 25519916, 29892012, 31515488, 32296183
GO:0005524	Function	ATP binding	IEA
GO:0005654	Component	Nucleoplasm	IDA
GO:0005737	Component	Cytoplasm	IBA
GO:0005737	Component	Cytoplasm	IEA
GO:0005794	Component	Golgi apparatus	IBA
GO:0005794	Component	Golgi apparatus	IEA
GO:0005798	Component	Golgi-associated vesicle	IEA
GO:0005829	Component	Cytosol	IDA
GO:0005886	Component	Plasma membrane	IDA
GO:0016020	Component	Membrane	IEA
GO:0016301	Function	Kinase activity	IEA
GO:0016604	Component	Nuclear body	IDA
GO:0016740	Function	Transferase activity	IEA
GO:0045944	Process	Positive regulation of transcription by RNA polymerase II	IEA
GO:0046777	Process	Protein autophosphorylation	IDA	18184589
GO:0048471	Component	Perinuclear region of cytoplasm	IEA
GO:0071560	Process	Cellular response to transforming growth factor beta stimulus	IEA
GO:0106310	Function	Protein serine kinase activity	IEA

Other IDs

• MIM: 604719
• HGNC: 11394
• e!Ensembl: ENSG00000115661

Protein

• UniProt ID: O75716
• Protein name: Serine/threonine-protein kinase 16 (EC 2.7.11.1) (Myristoylated and palmitoylated serine/threonine-protein kinase) (MPSK) (Protein kinase PKL12) (TGF-beta-stimulated factor 1) (TSF-1) (Tyrosine-protein kinase STK16) (EC 2.7.10.2) (hPSK)
• Protein function: Membrane-associated protein kinase that phosphorylates on serine and threonine residues. In vitro substrates include DRG1, ENO1 and EIF4EBP1. Also autophosphorylates. May be involved in secretory vesicle trafficking or intracellular signaling. M
• PDB: 2BUJ
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF00069	Pkinase	20 → 290	Protein kinase domain	Domain

• Tissue specificity: TISSUE SPECIFICITY: Ubiquitously expressed at very low levels. {ECO:0000269|PubMed:10364453}.
• Sequence:

  MGHALCVCSRGTVIIDNKRYLFIQKLGEGGFSYVDLVEGLHDGHFYALKRILCHEQQDRE
  EAQREADMHRLFNHPNILRLVAYCLRERGAKHEAWLLLPFFKRGTLWNEIERLKDKGNFL
  TEDQILWLLLGICRGLEAIHAKGYAHRDLKPTNILLGDEGQPVLMDLGSMNQACIHVEGS
  RQALTLQDWAAQRCTISYRAPELFSVQSHCVIDERTDVWSLGCVLYAMMFGEGPYDMVFQ
  KGDSVALAVQNQLSIPQSPRHSSALRQLLNSMMTVDPHQRPHIPLLLSQLEALQPPAPGQ
  HTTQI

• Sequence length: 305

Related Genes

No strongly related genes found yet for STK16.

Diseases Linked via Similar Genes

No additional diseases found yet through genes similar to STK16.