STK11IP (serine/threonine kinase 11 interacting protein)

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Gene miRNA Gene ontology Other IDs Protein Pathways Related genes Diseases linked via similar genes

Gene

• Entrez ID: 114790
• Gene name: Serine/threonine kinase 11 interacting protein
• Gene symbol: STK11IP
• Synonyms (NCBI Gene): LIP1, LKB1IP, STK11IP1
• Chromosome: 2
• Chromosome location: 2q35

miRNA Show/Hide all (51)

miRTarBase ID	miRNA	Experiments	Reference
MIRT046306	hsa-miR-23b-3p	CLASH	23622248
MIRT205283	hsa-miR-106a-5p	PAR-CLIP	21572407
MIRT205282	hsa-miR-93-5p	PAR-CLIP	21572407
MIRT205287	hsa-miR-526b-3p	PAR-CLIP	21572407
MIRT205289	hsa-miR-519d-3p	PAR-CLIP	21572407
MIRT205284	hsa-miR-106b-5p	PAR-CLIP	21572407
MIRT205285	hsa-miR-20b-5p	PAR-CLIP	21572407
MIRT205281	hsa-miR-20a-5p	PAR-CLIP	21572407
MIRT205280	hsa-miR-17-5p	PAR-CLIP	21572407
MIRT205294	hsa-miR-548az-5p	PAR-CLIP	21572407
MIRT205291	hsa-miR-548t-5p	PAR-CLIP	21572407
MIRT205290	hsa-miR-519a-3p	PAR-CLIP	21572407
MIRT205288	hsa-miR-519b-3p	PAR-CLIP	21572407
MIRT205286	hsa-miR-519c-3p	PAR-CLIP	21572407
MIRT553924	hsa-miR-5193	PAR-CLIP	21572407
MIRT553925	hsa-miR-660-3p	PAR-CLIP	21572407
MIRT553923	hsa-miR-4324	PAR-CLIP	21572407
MIRT205293	hsa-miR-4251	PAR-CLIP	21572407
MIRT553922	hsa-miR-539-5p	PAR-CLIP	21572407
MIRT553921	hsa-miR-873-5p	PAR-CLIP	21572407
MIRT553920	hsa-miR-1286	PAR-CLIP	21572407
MIRT553919	hsa-miR-4722-5p	PAR-CLIP	21572407
MIRT205292	hsa-miR-3148	PAR-CLIP	21572407
MIRT553918	hsa-miR-4691-5p	PAR-CLIP	21572407
MIRT553917	hsa-miR-6792-3p	PAR-CLIP	21572407
MIRT553916	hsa-miR-6749-3p	PAR-CLIP	21572407
MIRT205283	hsa-miR-106a-5p	PAR-CLIP	21572407
MIRT205282	hsa-miR-93-5p	PAR-CLIP	21572407
MIRT205287	hsa-miR-526b-3p	PAR-CLIP	21572407
MIRT205289	hsa-miR-519d-3p	PAR-CLIP	21572407
MIRT205284	hsa-miR-106b-5p	PAR-CLIP	21572407
MIRT205285	hsa-miR-20b-5p	PAR-CLIP	21572407
MIRT205281	hsa-miR-20a-5p	PAR-CLIP	21572407
MIRT205280	hsa-miR-17-5p	PAR-CLIP	21572407
MIRT205294	hsa-miR-548az-5p	PAR-CLIP	21572407
MIRT205291	hsa-miR-548t-5p	PAR-CLIP	21572407
MIRT205290	hsa-miR-519a-3p	PAR-CLIP	21572407
MIRT205288	hsa-miR-519b-3p	PAR-CLIP	21572407
MIRT205286	hsa-miR-519c-3p	PAR-CLIP	21572407
MIRT553924	hsa-miR-5193	PAR-CLIP	21572407
MIRT553925	hsa-miR-660-3p	PAR-CLIP	21572407
MIRT553923	hsa-miR-4324	PAR-CLIP	21572407
MIRT205293	hsa-miR-4251	PAR-CLIP	21572407
MIRT553922	hsa-miR-539-5p	PAR-CLIP	21572407
MIRT553921	hsa-miR-873-5p	PAR-CLIP	21572407
MIRT553920	hsa-miR-1286	PAR-CLIP	21572407
MIRT553919	hsa-miR-4722-5p	PAR-CLIP	21572407
MIRT205292	hsa-miR-3148	PAR-CLIP	21572407
MIRT553918	hsa-miR-4691-5p	PAR-CLIP	21572407
MIRT553917	hsa-miR-6792-3p	PAR-CLIP	21572407
MIRT553916	hsa-miR-6749-3p	PAR-CLIP	21572407

Gene ontology (GO) Show/Hide all (9)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005576	Component	Extracellular region	TAS
GO:0005737	Component	Cytoplasm	IBA
GO:0005737	Component	Cytoplasm	IDA	11741830
GO:0005737	Component	Cytoplasm	IEA
GO:0005765	Component	Lysosomal membrane	HDA	17897319
GO:0008104	Process	Intracellular protein localization	IBA
GO:0008104	Process	Intracellular protein localization	IDA	11741830
GO:0019901	Function	Protein kinase binding	IPI	11741830
GO:0035578	Component	Azurophil granule lumen	TAS

Other IDs

• MIM: 607172
• HGNC: 19184
• e!Ensembl: ENSG00000144589

Protein

• UniProt ID: Q8N1F8
• Protein name: Serine/threonine-protein kinase 11-interacting protein (LKB1-interacting protein 1)
• Protein function: May regulate STK11/LKB1 function by controlling its subcellular localization.
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF15904	LIP1	4 → 94	LKB1 serine/threonine kinase interacting protein 1	Family

• Sequence:

  MTTAQRDSLLWKLAGLLRESGDVVLSGCSTLSLLTPTLQQLNHVFELHLGPWGPGQTGFV
  ALPSHPADSPVILQLQFLFDVLQKTLSLKLVHVAGPGPTGPIKIFPFKSLRHLELRGVPL
  HCLHGLRGIYSQLETLICSRSLQALEELLSACGGDFCSALPWLALLSANFSYNALTALDS
  SLRLLSALRFLNLSHNQVQDCQGFLMDLCELHHLDISYNRLHLVPRMGPSGAALGVLILR
  GNELRSLHGLEQLRNLRHLDLAYNLLEGHRELSPLWLLAELRKLYLEGNPLWFHPEHRAA
  TAQYLSPRARDAATGFLLDGKVLSLTDFQTHTSLGLSPMGPPLPWPVGSTPETSGGPDLS
  DSLSSGGVVTQPLLHKVKSRVRVRRASISEPSDTDPEPRTLNPSPAGWFVQQHPELELMS
  SFRERFGRNWLQYRSHLEPSGNPLPATPTTSAPSAPPASSQGPDTAPRPSPPQEEARGPQ
  ESPQKMSEEVRAEPQEEEEEKEGKEEKEEGEMVEQGEEEAGEEEEEEQDQKEVEAELCRP
  LLVCPLEGPEGVRGRECFLRVTSAHLFEVELQAARTLERLELQSLEAAEIEPEAQAQRSP
  RPTGSDLLPGAPILSLRFSYICPDRQLRRYLVLEPDAHAAVQELLAVLTPVTNVAREQLG
  EARDLLLGRFQCLRCGHEFKPEEPRMGLDSEEGWRPLFQKTESPAVCPNCGSDHVVLLAV
  SRGTPNRERKQGEQSLAPSPSASPVCHPPGHGDHLDRAKNSPPQAPSTRDHGSWSLSPPP
  ERCGLRSVDHRLRLFLDVEVFSDAQEEFQCCLKVPVALAGHTGEFMCLVVVSDRRLYLLK
  VTGEMREPPASWLQLTLAVPLQDLSGIELGLAGQSLRLEWAAGAGRCVLLPRDARHCRAF
  LEELLDVLQSLPPAWRNCVSATEEEVTPQHRLWPLLEKDSSLEARQFFYLRAFLVEGPST
  CLVSLLLTPSTLFLLDEDAAGSPAEPSPPAASGEASEKVPPSGPGPAVRVREQQPLSSLS
  SVLLYRSAPEDLRLLFYDEVSRLESFWALRVVCQEQLTALLAWIREPWEELFSIGLRTVI
  QEALALDR

• Sequence length: 1088

Pathways

Reactome Pathway:

Neutrophil degranulation

Related Genes

No strongly related genes found yet for STK11IP.

Diseases Linked via Similar Genes

No additional diseases found yet through genes similar to STK11IP.