STARD5 (StAR related lipid transfer domain containing 5)

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Gene miRNA Gene ontology Other IDs Protein Pathways Related genes Diseases linked via similar genes

Gene

• Entrez ID: 80765
• Gene name: StAR related lipid transfer domain containing 5
• Gene symbol: STARD5
• Synonyms (NCBI Gene): -
• Chromosome: 15
• Chromosome location: 15q25.1
• Summary: Proteins containing a steroidogenic acute regulatory-related lipid transfer (START) domain are often involved in the trafficking of lipids and cholesterol between diverse intracellular membranes. This gene is a member of the StarD subfamily that encodes S

miRNA Show/Hide all (69)

miRTarBase ID	miRNA	Experiments	Reference
MIRT018134	hsa-miR-335-5p	Microarray	18185580
MIRT029733	hsa-miR-26b-5p	Microarray	19088304
MIRT047946	hsa-miR-30c-5p	CLASH	23622248
MIRT641286	hsa-miR-1236-3p	HITS-CLIP	23824327
MIRT641285	hsa-miR-3124-3p	HITS-CLIP	23824327
MIRT641284	hsa-miR-24-1-5p	HITS-CLIP	23824327
MIRT641283	hsa-miR-24-2-5p	HITS-CLIP	23824327
MIRT641282	hsa-miR-378a-5p	HITS-CLIP	23824327
MIRT641281	hsa-miR-1200	HITS-CLIP	23824327
MIRT641280	hsa-miR-3074-5p	HITS-CLIP	23824327
MIRT641279	hsa-miR-7152-5p	HITS-CLIP	23824327
MIRT530743	hsa-miR-224-5p	PAR-CLIP	22012620
MIRT447054	hsa-miR-5007-5p	PAR-CLIP	22012620
MIRT447053	hsa-miR-4502	PAR-CLIP	22012620
MIRT530742	hsa-miR-4452	PAR-CLIP	22012620
MIRT530741	hsa-miR-4263	PAR-CLIP	22012620
MIRT447054	hsa-miR-5007-5p	PAR-CLIP	22100165
MIRT447053	hsa-miR-4502	PAR-CLIP	22100165
MIRT447052	hsa-miR-4635	PAR-CLIP	22100165
MIRT447051	hsa-miR-3682-3p	PAR-CLIP	22100165
MIRT447050	hsa-miR-526b-5p	PAR-CLIP	22100165
MIRT447049	hsa-miR-578	PAR-CLIP	22100165
MIRT447054	hsa-miR-5007-5p	PAR-CLIP	22100165
MIRT447053	hsa-miR-4502	PAR-CLIP	22100165
MIRT447052	hsa-miR-4635	PAR-CLIP	22100165
MIRT447051	hsa-miR-3682-3p	PAR-CLIP	22100165
MIRT447050	hsa-miR-526b-5p	PAR-CLIP	22100165
MIRT447049	hsa-miR-578	PAR-CLIP	22100165
MIRT641286	hsa-miR-1236-3p	HITS-CLIP	23824327
MIRT641285	hsa-miR-3124-3p	HITS-CLIP	23824327
MIRT641284	hsa-miR-24-1-5p	HITS-CLIP	23824327
MIRT641283	hsa-miR-24-2-5p	HITS-CLIP	23824327
MIRT641282	hsa-miR-378a-5p	HITS-CLIP	23824327
MIRT641281	hsa-miR-1200	HITS-CLIP	23824327
MIRT641280	hsa-miR-3074-5p	HITS-CLIP	23824327
MIRT641279	hsa-miR-7152-5p	HITS-CLIP	23824327
MIRT530743	hsa-miR-224-5p	PAR-CLIP	22012620
MIRT447054	hsa-miR-5007-5p	PAR-CLIP	22012620
MIRT447053	hsa-miR-4502	PAR-CLIP	22012620
MIRT530742	hsa-miR-4452	PAR-CLIP	22012620
MIRT530741	hsa-miR-4263	PAR-CLIP	22012620
MIRT447054	hsa-miR-5007-5p	PAR-CLIP	22100165
MIRT447053	hsa-miR-4502	PAR-CLIP	22100165
MIRT447052	hsa-miR-4635	PAR-CLIP	22100165
MIRT447051	hsa-miR-3682-3p	PAR-CLIP	22100165
MIRT447050	hsa-miR-526b-5p	PAR-CLIP	22100165
MIRT447049	hsa-miR-578	PAR-CLIP	22100165
MIRT447054	hsa-miR-5007-5p	PAR-CLIP	22100165
MIRT447053	hsa-miR-4502	PAR-CLIP	22100165
MIRT447052	hsa-miR-4635	PAR-CLIP	22100165
MIRT447051	hsa-miR-3682-3p	PAR-CLIP	22100165
MIRT447050	hsa-miR-526b-5p	PAR-CLIP	22100165
MIRT447049	hsa-miR-578	PAR-CLIP	22100165
MIRT1395401	hsa-miR-103a	CLIP-seq
MIRT1395402	hsa-miR-107	CLIP-seq
MIRT1395403	hsa-miR-1184	CLIP-seq
MIRT1395404	hsa-miR-3126-5p	CLIP-seq
MIRT1395405	hsa-miR-3169	CLIP-seq
MIRT1395406	hsa-miR-4419a	CLIP-seq
MIRT1395407	hsa-miR-4510	CLIP-seq
MIRT1395408	hsa-miR-4700-3p	CLIP-seq
MIRT1395409	hsa-miR-4740-5p	CLIP-seq
MIRT2340869	hsa-miR-1225-5p	CLIP-seq
MIRT2340870	hsa-miR-194	CLIP-seq
MIRT2340871	hsa-miR-3676	CLIP-seq
MIRT2340872	hsa-miR-4514	CLIP-seq
MIRT2340873	hsa-miR-4534	CLIP-seq
MIRT2340874	hsa-miR-4692	CLIP-seq
MIRT2340875	hsa-miR-555	CLIP-seq

Gene ontology (GO) Show/Hide all (9)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005829	Component	Cytosol	TAS
GO:0006869	Process	Lipid transport	IEA
GO:0008289	Function	Lipid binding	IEA
GO:0015485	Function	Cholesterol binding	IBA
GO:0015485	Function	Cholesterol binding	IDA	18403318
GO:0070508	Process	Cholesterol import	IBA
GO:0070508	Process	Cholesterol import	IDA	18403318
GO:0120020	Function	Cholesterol transfer activity	IBA
GO:0120020	Function	Cholesterol transfer activity	IDA	18403318

Other IDs

• MIM: 607050
• HGNC: 18065
• e!Ensembl: ENSG00000172345

Protein

• UniProt ID: Q9NSY2
• Protein name: StAR-related lipid transfer protein 5 (START domain-containing protein 5) (StARD5)
• Protein function: May be involved in the intracellular transport of sterols or other lipids. May bind cholesterol or other sterols (By similarity).
• PDB: 2R55
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF01852	START	7 → 213	START domain	Domain

• Sequence:

  MDPALAAQMSEAVAEKMLQYRRDTAGWKICREGNGVSVSWRPSVEFPGNLYRGEGIVYGT
  LEEVWDCVKPAVGGLRVKWDENVTGFEIIQSITDTLCVSRTSTPSAAMKLISPRDFVDLV
  LVKRYEDGTISSNATHVEHPLCPPKPGFVRGFNHPCGCFCEPLPGEPTKTNLVTFFHTDL
  SGYLPQNVVDSFFPRSMTRFYANLQKAVKQFHE

• Sequence length: 213

Pathways

Reactome Pathway:

Recycling of bile acids and salts

Related Genes

No strongly related genes found yet for STARD5.

Diseases Linked via Similar Genes

No additional diseases found yet through genes similar to STARD5.