SRPK1 (SRSF protein kinase 1)

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Gene miRNA Gene ontology Other IDs Protein Pathways Related genes Diseases linked via similar genes

Gene

• Entrez ID: 6732
• Gene name: SRSF protein kinase 1
• Gene symbol: SRPK1
• Synonyms (NCBI Gene): SFRSK1
• Chromosome: 6
• Chromosome location: 6p21.31
• Summary: This gene encodes a serine/arginine protein kinase specific for the SR (serine/arginine-rich domain) family of splicing factors. The protein localizes to the nucleus and the cytoplasm. It is thought to play a role in regulation of both constitutive and al

miRNA Show/Hide all (349)

miRTarBase ID	miRNA	Experiments	Reference
MIRT028016	hsa-miR-93-5p	Sequencing	20371350
MIRT031711	hsa-miR-16-5p	Proteomics	18668040
MIRT048634	hsa-miR-99a-5p	CLASH	23622248
MIRT045199	hsa-miR-186-5p	CLASH	23622248
MIRT039559	hsa-miR-652-3p	CLASH	23622248
MIRT572707	hsa-miR-3156-5p	PAR-CLIP	20371350
MIRT572706	hsa-miR-22-3p	PAR-CLIP	20371350
MIRT572705	hsa-miR-139-5p	PAR-CLIP	20371350
MIRT572704	hsa-miR-6882-3p	PAR-CLIP	20371350
MIRT572703	hsa-miR-7-5p	PAR-CLIP	20371350
MIRT572702	hsa-miR-6077	PAR-CLIP	20371350
MIRT534074	hsa-miR-1252-3p	PAR-CLIP	22012620
MIRT534073	hsa-miR-3973	PAR-CLIP	22012620
MIRT534072	hsa-miR-3653-5p	PAR-CLIP	22012620
MIRT534071	hsa-miR-1976	PAR-CLIP	22012620
MIRT534070	hsa-miR-376a-2-5p	PAR-CLIP	22012620
MIRT534069	hsa-miR-376a-5p	PAR-CLIP	22012620
MIRT505518	hsa-miR-548m	PAR-CLIP	22012620
MIRT505517	hsa-miR-99a-3p	PAR-CLIP	22012620
MIRT505516	hsa-miR-99b-3p	PAR-CLIP	22012620
MIRT505515	hsa-miR-6796-3p	PAR-CLIP	22012620
MIRT505513	hsa-miR-4802-3p	PAR-CLIP	22012620
MIRT505514	hsa-miR-942-3p	PAR-CLIP	22012620
MIRT505512	hsa-miR-619-3p	PAR-CLIP	22012620
MIRT505511	hsa-miR-7851-3p	PAR-CLIP	22012620
MIRT505510	hsa-miR-6890-5p	PAR-CLIP	22012620
MIRT100521	hsa-miR-95-5p	PAR-CLIP	22012620
MIRT505508	hsa-miR-7158-5p	PAR-CLIP	22012620
MIRT505509	hsa-miR-6881-5p	PAR-CLIP	22012620
MIRT505518	hsa-miR-548m	PAR-CLIP	23446348
MIRT505517	hsa-miR-99a-3p	PAR-CLIP	23446348
MIRT505516	hsa-miR-99b-3p	PAR-CLIP	23446348
MIRT505515	hsa-miR-6796-3p	PAR-CLIP	23446348
MIRT505513	hsa-miR-4802-3p	PAR-CLIP	23446348
MIRT505514	hsa-miR-942-3p	PAR-CLIP	23446348
MIRT505512	hsa-miR-619-3p	PAR-CLIP	23446348
MIRT505511	hsa-miR-7851-3p	PAR-CLIP	23446348
MIRT505510	hsa-miR-6890-5p	PAR-CLIP	23446348
MIRT100521	hsa-miR-95-5p	PAR-CLIP	23446348
MIRT505508	hsa-miR-7158-5p	PAR-CLIP	23446348
MIRT505509	hsa-miR-6881-5p	PAR-CLIP	23446348
MIRT505518	hsa-miR-548m	PAR-CLIP	23446348
MIRT505517	hsa-miR-99a-3p	PAR-CLIP	23446348
MIRT505516	hsa-miR-99b-3p	PAR-CLIP	23446348
MIRT505515	hsa-miR-6796-3p	PAR-CLIP	23446348
MIRT505513	hsa-miR-4802-3p	PAR-CLIP	23446348
MIRT505514	hsa-miR-942-3p	PAR-CLIP	23446348
MIRT505512	hsa-miR-619-3p	PAR-CLIP	23446348
MIRT505511	hsa-miR-7851-3p	PAR-CLIP	23446348
MIRT505510	hsa-miR-6890-5p	PAR-CLIP	23446348
MIRT100521	hsa-miR-95-5p	PAR-CLIP	23446348
MIRT505508	hsa-miR-7158-5p	PAR-CLIP	23446348
MIRT505509	hsa-miR-6881-5p	PAR-CLIP	23446348
MIRT441789	hsa-miR-4753-5p	PAR-CLIP	22100165
MIRT441788	hsa-miR-3922-5p	PAR-CLIP	22100165
MIRT441787	hsa-miR-3926	PAR-CLIP	22100165
MIRT726455	hsa-miR-15a-5p	HITS-CLIP	22473208
MIRT726454	hsa-miR-15b-5p	HITS-CLIP	22473208
MIRT031711	hsa-miR-16-5p	HITS-CLIP	22473208
MIRT726453	hsa-miR-195-5p	HITS-CLIP	22473208
MIRT572707	hsa-miR-3156-5p	PAR-CLIP	20371350
MIRT572706	hsa-miR-22-3p	PAR-CLIP	20371350
MIRT572705	hsa-miR-139-5p	PAR-CLIP	20371350
MIRT572704	hsa-miR-6882-3p	PAR-CLIP	20371350
MIRT572703	hsa-miR-7-5p	PAR-CLIP	20371350
MIRT572702	hsa-miR-6077	PAR-CLIP	20371350
MIRT534074	hsa-miR-1252-3p	PAR-CLIP	22012620
MIRT534073	hsa-miR-3973	PAR-CLIP	22012620
MIRT534072	hsa-miR-3653-5p	PAR-CLIP	22012620
MIRT534071	hsa-miR-1976	PAR-CLIP	22012620
MIRT534070	hsa-miR-376a-2-5p	PAR-CLIP	22012620
MIRT534069	hsa-miR-376a-5p	PAR-CLIP	22012620
MIRT505518	hsa-miR-548m	PAR-CLIP	22012620
MIRT505517	hsa-miR-99a-3p	PAR-CLIP	22012620
MIRT505516	hsa-miR-99b-3p	PAR-CLIP	22012620
MIRT505515	hsa-miR-6796-3p	PAR-CLIP	22012620
MIRT505513	hsa-miR-4802-3p	PAR-CLIP	22012620
MIRT505514	hsa-miR-942-3p	PAR-CLIP	22012620
MIRT505512	hsa-miR-619-3p	PAR-CLIP	22012620
MIRT505511	hsa-miR-7851-3p	PAR-CLIP	22012620
MIRT505510	hsa-miR-6890-5p	PAR-CLIP	22012620
MIRT100521	hsa-miR-95-5p	PAR-CLIP	22012620
MIRT505508	hsa-miR-7158-5p	PAR-CLIP	22012620
MIRT505509	hsa-miR-6881-5p	PAR-CLIP	22012620
MIRT505518	hsa-miR-548m	PAR-CLIP	23446348
MIRT505517	hsa-miR-99a-3p	PAR-CLIP	23446348
MIRT505516	hsa-miR-99b-3p	PAR-CLIP	23446348
MIRT505515	hsa-miR-6796-3p	PAR-CLIP	23446348
MIRT505513	hsa-miR-4802-3p	PAR-CLIP	23446348
MIRT505514	hsa-miR-942-3p	PAR-CLIP	23446348
MIRT505512	hsa-miR-619-3p	PAR-CLIP	23446348
MIRT505511	hsa-miR-7851-3p	PAR-CLIP	23446348
MIRT505510	hsa-miR-6890-5p	PAR-CLIP	23446348
MIRT100521	hsa-miR-95-5p	PAR-CLIP	23446348
MIRT505508	hsa-miR-7158-5p	PAR-CLIP	23446348
MIRT505509	hsa-miR-6881-5p	PAR-CLIP	23446348
MIRT505518	hsa-miR-548m	PAR-CLIP	23446348
MIRT505517	hsa-miR-99a-3p	PAR-CLIP	23446348
MIRT505516	hsa-miR-99b-3p	PAR-CLIP	23446348
MIRT505515	hsa-miR-6796-3p	PAR-CLIP	23446348
MIRT505513	hsa-miR-4802-3p	PAR-CLIP	23446348
MIRT505514	hsa-miR-942-3p	PAR-CLIP	23446348
MIRT505512	hsa-miR-619-3p	PAR-CLIP	23446348
MIRT505511	hsa-miR-7851-3p	PAR-CLIP	23446348
MIRT505510	hsa-miR-6890-5p	PAR-CLIP	23446348
MIRT100521	hsa-miR-95-5p	PAR-CLIP	23446348
MIRT505508	hsa-miR-7158-5p	PAR-CLIP	23446348
MIRT505509	hsa-miR-6881-5p	PAR-CLIP	23446348
MIRT441789	hsa-miR-4753-5p	PAR-CLIP	22100165
MIRT441788	hsa-miR-3922-5p	PAR-CLIP	22100165
MIRT441787	hsa-miR-3926	PAR-CLIP	22100165
MIRT1389396	hsa-miR-129-5p	CLIP-seq
MIRT1389397	hsa-miR-1297	CLIP-seq
MIRT1389398	hsa-miR-137	CLIP-seq
MIRT1389399	hsa-miR-15a	CLIP-seq
MIRT1389400	hsa-miR-15b	CLIP-seq
MIRT1389401	hsa-miR-16	CLIP-seq
MIRT1389402	hsa-miR-186	CLIP-seq
MIRT1389403	hsa-miR-1909	CLIP-seq
MIRT1389404	hsa-miR-195	CLIP-seq
MIRT1389405	hsa-miR-21	CLIP-seq
MIRT1389406	hsa-miR-26a	CLIP-seq
MIRT1389407	hsa-miR-26b	CLIP-seq
MIRT1389408	hsa-miR-3123	CLIP-seq
MIRT1389409	hsa-miR-3133	CLIP-seq
MIRT1389410	hsa-miR-3168	CLIP-seq
MIRT1389411	hsa-miR-3199	CLIP-seq
MIRT1389412	hsa-miR-320a	CLIP-seq
MIRT1389413	hsa-miR-320b	CLIP-seq
MIRT1389414	hsa-miR-320c	CLIP-seq
MIRT1389415	hsa-miR-320d	CLIP-seq
MIRT1389416	hsa-miR-323-3p	CLIP-seq
MIRT1389417	hsa-miR-3646	CLIP-seq
MIRT1389418	hsa-miR-3668	CLIP-seq
MIRT1389419	hsa-miR-3692	CLIP-seq
MIRT1389420	hsa-miR-3919	CLIP-seq
MIRT1389421	hsa-miR-3924	CLIP-seq
MIRT1389422	hsa-miR-424	CLIP-seq
MIRT1389423	hsa-miR-4277	CLIP-seq
MIRT1389424	hsa-miR-4429	CLIP-seq
MIRT1389425	hsa-miR-4465	CLIP-seq
MIRT1389426	hsa-miR-4495	CLIP-seq
MIRT1389427	hsa-miR-452	CLIP-seq
MIRT1389428	hsa-miR-4524	CLIP-seq
MIRT1389429	hsa-miR-4645-3p	CLIP-seq
MIRT1389430	hsa-miR-4652-3p	CLIP-seq
MIRT1389431	hsa-miR-4652-5p	CLIP-seq
MIRT1389432	hsa-miR-4676-3p	CLIP-seq
MIRT1389433	hsa-miR-4698	CLIP-seq
MIRT1389434	hsa-miR-4699-5p	CLIP-seq
MIRT1389435	hsa-miR-4705	CLIP-seq
MIRT1389436	hsa-miR-4718	CLIP-seq
MIRT1389437	hsa-miR-4760-3p	CLIP-seq
MIRT1389438	hsa-miR-4760-5p	CLIP-seq
MIRT1389439	hsa-miR-4781-3p	CLIP-seq
MIRT1389440	hsa-miR-488	CLIP-seq
MIRT1389441	hsa-miR-497	CLIP-seq
MIRT1389442	hsa-miR-503	CLIP-seq
MIRT1389443	hsa-miR-514	CLIP-seq
MIRT1389444	hsa-miR-514b-3p	CLIP-seq
MIRT1389445	hsa-miR-548ac	CLIP-seq
MIRT1389446	hsa-miR-548ae	CLIP-seq
MIRT1389447	hsa-miR-548aj	CLIP-seq
MIRT1389448	hsa-miR-548am	CLIP-seq
MIRT1389449	hsa-miR-548c-3p	CLIP-seq
MIRT1389450	hsa-miR-548d-3p	CLIP-seq
MIRT1389451	hsa-miR-548n	CLIP-seq
MIRT1389452	hsa-miR-548t	CLIP-seq
MIRT1389453	hsa-miR-548x	CLIP-seq
MIRT1389454	hsa-miR-548z	CLIP-seq
MIRT1389455	hsa-miR-554	CLIP-seq
MIRT1389456	hsa-miR-570	CLIP-seq
MIRT1389457	hsa-miR-576-3p	CLIP-seq
MIRT1389458	hsa-miR-590-5p	CLIP-seq
MIRT1389459	hsa-miR-646	CLIP-seq
MIRT1389460	hsa-miR-922	CLIP-seq
MIRT2116713	hsa-miR-1296	CLIP-seq
MIRT1389402	hsa-miR-186	CLIP-seq
MIRT2116714	hsa-miR-2052	CLIP-seq
MIRT2116715	hsa-miR-2113	CLIP-seq
MIRT2116716	hsa-miR-4512	CLIP-seq
MIRT2116717	hsa-miR-4773	CLIP-seq
MIRT2116718	hsa-miR-599	CLIP-seq
MIRT2339088	hsa-miR-1226	CLIP-seq
MIRT2339089	hsa-miR-1252	CLIP-seq
MIRT2339090	hsa-miR-132	CLIP-seq
MIRT2339091	hsa-miR-1322	CLIP-seq
MIRT1389399	hsa-miR-15a	CLIP-seq
MIRT1389400	hsa-miR-15b	CLIP-seq
MIRT1389401	hsa-miR-16	CLIP-seq
MIRT1389402	hsa-miR-186	CLIP-seq
MIRT2339092	hsa-miR-1911	CLIP-seq
MIRT1389404	hsa-miR-195	CLIP-seq
MIRT2339093	hsa-miR-212	CLIP-seq
MIRT2339094	hsa-miR-3120-3p	CLIP-seq
MIRT1389408	hsa-miR-3123	CLIP-seq
MIRT2339095	hsa-miR-3148	CLIP-seq
MIRT1389418	hsa-miR-3668	CLIP-seq
MIRT2339096	hsa-miR-3687	CLIP-seq
MIRT1389420	hsa-miR-3919	CLIP-seq
MIRT2339097	hsa-miR-3920	CLIP-seq
MIRT2339098	hsa-miR-3940-3p	CLIP-seq
MIRT2339099	hsa-miR-409-5p	CLIP-seq
MIRT1389422	hsa-miR-424	CLIP-seq
MIRT2339100	hsa-miR-4433	CLIP-seq
MIRT2339101	hsa-miR-4442	CLIP-seq
MIRT2339102	hsa-miR-4454	CLIP-seq
MIRT2339103	hsa-miR-4459	CLIP-seq
MIRT1389428	hsa-miR-4524	CLIP-seq
MIRT2339104	hsa-miR-455-3p	CLIP-seq
MIRT2339105	hsa-miR-4661-3p	CLIP-seq
MIRT2339106	hsa-miR-4700-3p	CLIP-seq
MIRT2339107	hsa-miR-4733-3p	CLIP-seq
MIRT2339108	hsa-miR-4768-3p	CLIP-seq
MIRT2339109	hsa-miR-486-5p	CLIP-seq
MIRT1389441	hsa-miR-497	CLIP-seq
MIRT1389442	hsa-miR-503	CLIP-seq
MIRT2339110	hsa-miR-5096	CLIP-seq
MIRT1389459	hsa-miR-646	CLIP-seq
MIRT2339111	hsa-miR-654-3p	CLIP-seq
MIRT2339112	hsa-miR-665	CLIP-seq
MIRT2339113	hsa-miR-873	CLIP-seq
MIRT2339114	hsa-miR-876-3p	CLIP-seq
MIRT2339115	hsa-miR-889	CLIP-seq
MIRT1389460	hsa-miR-922	CLIP-seq
MIRT2339094	hsa-miR-3120-3p	CLIP-seq
MIRT2395173	hsa-miR-3165	CLIP-seq
MIRT2433544	hsa-miR-374a	CLIP-seq
MIRT2433545	hsa-miR-374b	CLIP-seq
MIRT2632764	hsa-miR-1204	CLIP-seq
MIRT2339088	hsa-miR-1226	CLIP-seq
MIRT2632765	hsa-miR-1263	CLIP-seq
MIRT2116713	hsa-miR-1296	CLIP-seq
MIRT1389398	hsa-miR-137	CLIP-seq
MIRT2632766	hsa-miR-144	CLIP-seq
MIRT2632767	hsa-miR-153	CLIP-seq
MIRT1389399	hsa-miR-15a	CLIP-seq
MIRT1389400	hsa-miR-15b	CLIP-seq
MIRT1389401	hsa-miR-16	CLIP-seq
MIRT1389404	hsa-miR-195	CLIP-seq
MIRT2116714	hsa-miR-2052	CLIP-seq
MIRT2116715	hsa-miR-2113	CLIP-seq
MIRT2632768	hsa-miR-22	CLIP-seq
MIRT2632769	hsa-miR-2277-3p	CLIP-seq
MIRT2339094	hsa-miR-3120-3p	CLIP-seq
MIRT2632770	hsa-miR-3121-3p	CLIP-seq
MIRT1389408	hsa-miR-3123	CLIP-seq
MIRT2632771	hsa-miR-3163	CLIP-seq
MIRT1389410	hsa-miR-3168	CLIP-seq
MIRT2632772	hsa-miR-3174	CLIP-seq
MIRT2632773	hsa-miR-3591-5p	CLIP-seq
MIRT2632774	hsa-miR-3606	CLIP-seq
MIRT2632775	hsa-miR-3662	CLIP-seq
MIRT1389418	hsa-miR-3668	CLIP-seq
MIRT2632776	hsa-miR-3688-5p	CLIP-seq
MIRT1389419	hsa-miR-3692	CLIP-seq
MIRT2433544	hsa-miR-374a	CLIP-seq
MIRT2433545	hsa-miR-374b	CLIP-seq
MIRT1389420	hsa-miR-3919	CLIP-seq
MIRT1389421	hsa-miR-3924	CLIP-seq
MIRT2339099	hsa-miR-409-5p	CLIP-seq
MIRT1389422	hsa-miR-424	CLIP-seq
MIRT1389423	hsa-miR-4277	CLIP-seq
MIRT2632777	hsa-miR-4282	CLIP-seq
MIRT2632778	hsa-miR-4456	CLIP-seq
MIRT2116716	hsa-miR-4512	CLIP-seq
MIRT1389428	hsa-miR-4524	CLIP-seq
MIRT1389429	hsa-miR-4645-3p	CLIP-seq
MIRT2632779	hsa-miR-4666-3p	CLIP-seq
MIRT2339107	hsa-miR-4733-3p	CLIP-seq
MIRT2632780	hsa-miR-4753-3p	CLIP-seq
MIRT1389437	hsa-miR-4760-3p	CLIP-seq
MIRT1389438	hsa-miR-4760-5p	CLIP-seq
MIRT2339109	hsa-miR-486-5p	CLIP-seq
MIRT1389441	hsa-miR-497	CLIP-seq
MIRT2632781	hsa-miR-500a	CLIP-seq
MIRT2632782	hsa-miR-501-5p	CLIP-seq
MIRT1389442	hsa-miR-503	CLIP-seq
MIRT2339110	hsa-miR-5096	CLIP-seq
MIRT1389443	hsa-miR-514	CLIP-seq
MIRT1389444	hsa-miR-514b-3p	CLIP-seq
MIRT2632783	hsa-miR-520f	CLIP-seq
MIRT2632784	hsa-miR-522	CLIP-seq
MIRT2632785	hsa-miR-526b	CLIP-seq
MIRT2632786	hsa-miR-545	CLIP-seq
MIRT1389455	hsa-miR-554	CLIP-seq
MIRT1389457	hsa-miR-576-3p	CLIP-seq
MIRT2116718	hsa-miR-599	CLIP-seq
MIRT2632787	hsa-miR-619	CLIP-seq
MIRT2632788	hsa-miR-621	CLIP-seq
MIRT1389459	hsa-miR-646	CLIP-seq
MIRT2632789	hsa-miR-7	CLIP-seq
MIRT2339114	hsa-miR-876-3p	CLIP-seq
MIRT2339115	hsa-miR-889	CLIP-seq
MIRT2632790	hsa-miR-921	CLIP-seq
MIRT1389460	hsa-miR-922	CLIP-seq
MIRT2632764	hsa-miR-1204	CLIP-seq
MIRT2339088	hsa-miR-1226	CLIP-seq
MIRT2116713	hsa-miR-1296	CLIP-seq
MIRT2632766	hsa-miR-144	CLIP-seq
MIRT2632767	hsa-miR-153	CLIP-seq
MIRT1389399	hsa-miR-15a	CLIP-seq
MIRT1389400	hsa-miR-15b	CLIP-seq
MIRT1389401	hsa-miR-16	CLIP-seq
MIRT1389404	hsa-miR-195	CLIP-seq
MIRT2116714	hsa-miR-2052	CLIP-seq
MIRT2116715	hsa-miR-2113	CLIP-seq
MIRT2632768	hsa-miR-22	CLIP-seq
MIRT2632769	hsa-miR-2277-3p	CLIP-seq
MIRT2339094	hsa-miR-3120-3p	CLIP-seq
MIRT2632770	hsa-miR-3121-3p	CLIP-seq
MIRT1389408	hsa-miR-3123	CLIP-seq
MIRT2632772	hsa-miR-3174	CLIP-seq
MIRT2632773	hsa-miR-3591-5p	CLIP-seq
MIRT2632774	hsa-miR-3606	CLIP-seq
MIRT1389418	hsa-miR-3668	CLIP-seq
MIRT2632776	hsa-miR-3688-5p	CLIP-seq
MIRT1389419	hsa-miR-3692	CLIP-seq
MIRT2433544	hsa-miR-374a	CLIP-seq
MIRT2433545	hsa-miR-374b	CLIP-seq
MIRT1389420	hsa-miR-3919	CLIP-seq
MIRT1389421	hsa-miR-3924	CLIP-seq
MIRT2339099	hsa-miR-409-5p	CLIP-seq
MIRT1389422	hsa-miR-424	CLIP-seq
MIRT2632778	hsa-miR-4456	CLIP-seq
MIRT2116716	hsa-miR-4512	CLIP-seq
MIRT1389428	hsa-miR-4524	CLIP-seq
MIRT1389429	hsa-miR-4645-3p	CLIP-seq
MIRT2632779	hsa-miR-4666-3p	CLIP-seq
MIRT2339107	hsa-miR-4733-3p	CLIP-seq
MIRT2632780	hsa-miR-4753-3p	CLIP-seq
MIRT2339109	hsa-miR-486-5p	CLIP-seq
MIRT1389441	hsa-miR-497	CLIP-seq
MIRT2632781	hsa-miR-500a	CLIP-seq
MIRT2632782	hsa-miR-501-5p	CLIP-seq
MIRT1389442	hsa-miR-503	CLIP-seq
MIRT2339110	hsa-miR-5096	CLIP-seq
MIRT1389443	hsa-miR-514	CLIP-seq
MIRT1389444	hsa-miR-514b-3p	CLIP-seq
MIRT2632785	hsa-miR-526b	CLIP-seq
MIRT2632786	hsa-miR-545	CLIP-seq
MIRT2116718	hsa-miR-599	CLIP-seq
MIRT2632787	hsa-miR-619	CLIP-seq
MIRT1389459	hsa-miR-646	CLIP-seq
MIRT2632789	hsa-miR-7	CLIP-seq
MIRT2339114	hsa-miR-876-3p	CLIP-seq
MIRT2339115	hsa-miR-889	CLIP-seq
MIRT2632790	hsa-miR-921	CLIP-seq
MIRT1389460	hsa-miR-922	CLIP-seq

Gene ontology (GO) Show/Hide all (52)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000166	Function	Nucleotide binding	IEA
GO:0000245	Process	Spliceosomal complex assembly	IBA
GO:0000287	Function	Magnesium ion binding	IDA	11509566
GO:0000287	Function	Magnesium ion binding	IEA
GO:0000785	Component	Chromatin	IDA	28076779
GO:0003723	Function	RNA binding	HDA	22681889
GO:0004672	Function	Protein kinase activity	IEA
GO:0004672	Function	Protein kinase activity	TAS	8208298
GO:0004674	Function	Protein serine/threonine kinase activity	IBA
GO:0004674	Function	Protein serine/threonine kinase activity	IDA	9237760, 11509566
GO:0004674	Function	Protein serine/threonine kinase activity	IEA
GO:0005515	Function	Protein binding	IPI	9237760, 10196197, 11509566, 17360743, 19674106, 21130767, 22365833, 23602568, 28514442, 30021884, 32707033, 32817937, 33247108, 33961781, 34029587, 35271311
GO:0005524	Function	ATP binding	IDA	11509566
GO:0005524	Function	ATP binding	IEA
GO:0005634	Component	Nucleus	IBA
GO:0005634	Component	Nucleus	IDA	11509566
GO:0005634	Component	Nucleus	IEA
GO:0005634	Component	Nucleus	TAS	8208298
GO:0005654	Component	Nucleoplasm	IDA	28076779
GO:0005654	Component	Nucleoplasm	IEA
GO:0005694	Component	Chromosome	IEA
GO:0005737	Component	Cytoplasm	IBA
GO:0005737	Component	Cytoplasm	IDA	11509566, 28076779
GO:0005737	Component	Cytoplasm	IEA
GO:0005783	Component	Endoplasmic reticulum	IEA
GO:0005829	Component	Cytosol	IDA
GO:0005829	Component	Cytosol	TAS
GO:0005886	Component	Plasma membrane	IDA
GO:0006397	Process	MRNA processing	IEA
GO:0006468	Process	Protein phosphorylation	IDA	9237760, 11509566
GO:0007059	Process	Chromosome segregation	IDA	15034300
GO:0007059	Process	Chromosome segregation	IEA
GO:0008380	Process	RNA splicing	IEA
GO:0008380	Process	RNA splicing	TAS	8208298
GO:0016301	Function	Kinase activity	IEA
GO:0016363	Component	Nuclear matrix	IEA
GO:0016607	Component	Nuclear speck	IDA	28076779
GO:0016607	Component	Nuclear speck	IEA
GO:0016740	Function	Transferase activity	IEA
GO:0030154	Process	Cell differentiation	IEA
GO:0035092	Process	Sperm DNA condensation	TAS	21205200
GO:0035556	Process	Intracellular signal transduction	IBA
GO:0035556	Process	Intracellular signal transduction	IDA	11509566
GO:0035556	Process	Intracellular signal transduction	IEA
GO:0045070	Process	Positive regulation of viral genome replication	IDA	20498328
GO:0045071	Process	Negative regulation of viral genome replication	IDA	12417631
GO:0045087	Process	Innate immune response	IC	12417631
GO:0048024	Process	Regulation of mRNA splicing, via spliceosome	TAS	21205200
GO:0050684	Process	Regulation of mRNA processing	IBA
GO:0050684	Process	Regulation of mRNA processing	IDA	8208298
GO:0050684	Process	Regulation of mRNA processing	IEA
GO:0106310	Function	Protein serine kinase activity	IEA

Other IDs

• MIM: 601939
• HGNC: 11305
• e!Ensembl: ENSG00000096063

Protein

• UniProt ID: Q96SB4
• Protein name: SRSF protein kinase 1 (EC 2.7.11.1) (SFRS protein kinase 1) (Serine/arginine-rich protein-specific kinase 1) (SR-protein-specific kinase 1)
• Protein function: Serine/arginine-rich protein-specific kinase which specifically phosphorylates its substrates at serine residues located in regions rich in arginine/serine dipeptides, known as RS domains and is involved in the phosphorylation of SR splicing fac
• PDB: 1WAK , 1WBP , 3BEG , 4WUA , 5MXX , 5MY8 , 5NNG , 5XV7 , 6FAD , 7DD1 , 7PQS , 7ZKS
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF00069	Pkinase	80 → 231	Protein kinase domain	Domain
  PF00069	Pkinase	475 → 653	Protein kinase domain	Domain

• Tissue specificity: TISSUE SPECIFICITY: Isoform 2 is predominantly expressed in the testis but is also present at lower levels in heart, ovary, small intestine, liver, kidney, pancreas and skeletal muscle. Isoform 1 is only seen in the testis, at lower levels than isoform 2.
• Sequence:

  MERKVLALQARKKRTKAKKDKAQRKSETQHRGSAPHSESDLPEQEEEILGSDDDEQEDPN
  DYCKGGYHLVKIGDLFNGRYHVIRKLGWGHFSTVWLSWDIQGKKFVAMKVVKSAEHYTET
  ALDEIRLLKSVRNSDPNDPNREMVVQLLDDFKISGVNGTHICMVFEVLGHHLLKWIIKSN
  YQGLPLPCVKKIIQQVLQGLDYLHTKCRIIHTDIKPENILLSVNEQYIRRLAAEATEWQR
  SGAPPPSGSAVSTAPQPKPADKMSKNKKKKLKKKQKRQAELLEKRMQEIEEMEKESGPGQ
  KRPNKQEESESPVERPLKENPPNKMTQEKLEESSTIGQDQTLMERDTEGGAAEINCNGVI
  EVINYTQNSNNETLRHKEDLHNANDCDVQNLNQESSFLSSQNGDSSTSQETDSCTPITSE
  VSDTMVCQSSSTVGQSFSEQHISQLQESIRAEIPCEDEQEQEHNGPLDNKGKSTAGNFLV
  NPLEPKNAEKLKVKIADLGNACWVHKHFTEDIQTRQYRSLEVLIGSGYNTPADIWSTACM
  AFELATGDYLFEPHSGEEYTRDEDHIALIIELLGKVPRKLIVAGKYSKEFFTKKGDLKHI
  TKLKPWGLFEVLVEKYEWSQEEAAGFTDFLLPMLELIPEKRATAAECLRHPWLNS

• Sequence length: 655

Pathways

KEGG Pathway:

Herpes simplex virus 1 infection

Related Genes

No strongly related genes found yet for SRPK1.

Diseases Linked via Similar Genes

No additional diseases found yet through genes similar to SRPK1.