SPRN (shadow of prion protein)

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Gene miRNA Gene ontology Other IDs Protein Pathways Related genes Diseases linked via similar genes

Gene

• Entrez ID: 503542
• Gene name: Shadow of prion protein
• Gene symbol: SPRN
• Synonyms (NCBI Gene): SHADOO, SHO, bA108K14.1
• Chromosome: 10
• Chromosome location: 10q26.3

miRNA Show/Hide all (156)

miRTarBase ID	miRNA	Experiments	Reference
MIRT1385888	hsa-miR-106a	CLIP-seq
MIRT1385889	hsa-miR-106b	CLIP-seq
MIRT1385890	hsa-miR-1207-5p	CLIP-seq
MIRT1385891	hsa-miR-1227	CLIP-seq
MIRT1385892	hsa-miR-1254	CLIP-seq
MIRT1385893	hsa-miR-1275	CLIP-seq
MIRT1385894	hsa-miR-1297	CLIP-seq
MIRT1385895	hsa-miR-1299	CLIP-seq
MIRT1385896	hsa-miR-17	CLIP-seq
MIRT1385897	hsa-miR-20a	CLIP-seq
MIRT1385898	hsa-miR-20b	CLIP-seq
MIRT1385899	hsa-miR-22	CLIP-seq
MIRT1385900	hsa-miR-26a	CLIP-seq
MIRT1385901	hsa-miR-26b	CLIP-seq
MIRT1385902	hsa-miR-3116	CLIP-seq
MIRT1385903	hsa-miR-3151	CLIP-seq
MIRT1385904	hsa-miR-3164	CLIP-seq
MIRT1385905	hsa-miR-3175	CLIP-seq
MIRT1385906	hsa-miR-3179	CLIP-seq
MIRT1385907	hsa-miR-3202	CLIP-seq
MIRT1385908	hsa-miR-3609	CLIP-seq
MIRT1385909	hsa-miR-3689a-3p	CLIP-seq
MIRT1385910	hsa-miR-3689c	CLIP-seq
MIRT1385911	hsa-miR-3689d	CLIP-seq
MIRT1385912	hsa-miR-3690	CLIP-seq
MIRT1385913	hsa-miR-3929	CLIP-seq
MIRT1385914	hsa-miR-3936	CLIP-seq
MIRT1385915	hsa-miR-4419b	CLIP-seq
MIRT1385916	hsa-miR-4434	CLIP-seq
MIRT1385917	hsa-miR-4447	CLIP-seq
MIRT1385918	hsa-miR-4453	CLIP-seq
MIRT1385919	hsa-miR-4455	CLIP-seq
MIRT1385920	hsa-miR-4465	CLIP-seq
MIRT1385921	hsa-miR-4472	CLIP-seq
MIRT1385922	hsa-miR-4478	CLIP-seq
MIRT1385923	hsa-miR-4493	CLIP-seq
MIRT1385924	hsa-miR-4514	CLIP-seq
MIRT1385925	hsa-miR-4516	CLIP-seq
MIRT1385926	hsa-miR-4520a-3p	CLIP-seq
MIRT1385927	hsa-miR-4525	CLIP-seq
MIRT1385928	hsa-miR-4527	CLIP-seq
MIRT1385929	hsa-miR-4533	CLIP-seq
MIRT1385930	hsa-miR-4538	CLIP-seq
MIRT1385931	hsa-miR-4638-3p	CLIP-seq
MIRT1385932	hsa-miR-4651	CLIP-seq
MIRT1385933	hsa-miR-4661-3p	CLIP-seq
MIRT1385934	hsa-miR-4665-5p	CLIP-seq
MIRT1385935	hsa-miR-4692	CLIP-seq
MIRT1385936	hsa-miR-4715-3p	CLIP-seq
MIRT1385937	hsa-miR-4716-3p	CLIP-seq
MIRT1385938	hsa-miR-4723-5p	CLIP-seq
MIRT1385939	hsa-miR-4728-5p	CLIP-seq
MIRT1385940	hsa-miR-4736	CLIP-seq
MIRT1385941	hsa-miR-4743	CLIP-seq
MIRT1385942	hsa-miR-4763-3p	CLIP-seq
MIRT1385943	hsa-miR-4796-3p	CLIP-seq
MIRT1385944	hsa-miR-491-5p	CLIP-seq
MIRT1385945	hsa-miR-498	CLIP-seq
MIRT1385946	hsa-miR-519d	CLIP-seq
MIRT1385947	hsa-miR-548ah	CLIP-seq
MIRT1385948	hsa-miR-608	CLIP-seq
MIRT1385949	hsa-miR-625	CLIP-seq
MIRT1385950	hsa-miR-647	CLIP-seq
MIRT1385951	hsa-miR-875-3p	CLIP-seq
MIRT1385952	hsa-miR-93	CLIP-seq
MIRT1385953	hsa-miR-939	CLIP-seq
MIRT2115483	hsa-miR-1285	CLIP-seq
MIRT2115484	hsa-miR-1908	CLIP-seq
MIRT2115485	hsa-miR-193a-3p	CLIP-seq
MIRT2115486	hsa-miR-193b	CLIP-seq
MIRT1385899	hsa-miR-22	CLIP-seq
MIRT2115487	hsa-miR-2467-3p	CLIP-seq
MIRT2115488	hsa-miR-296-5p	CLIP-seq
MIRT2115489	hsa-miR-3187-5p	CLIP-seq
MIRT2115490	hsa-miR-3199	CLIP-seq
MIRT2115491	hsa-miR-370	CLIP-seq
MIRT2115492	hsa-miR-378g	CLIP-seq
MIRT2115493	hsa-miR-4252	CLIP-seq
MIRT2115494	hsa-miR-4258	CLIP-seq
MIRT2115495	hsa-miR-4313	CLIP-seq
MIRT2115496	hsa-miR-4446-3p	CLIP-seq
MIRT2115497	hsa-miR-4486	CLIP-seq
MIRT1385924	hsa-miR-4514	CLIP-seq
MIRT2115498	hsa-miR-4515	CLIP-seq
MIRT2115499	hsa-miR-4646-5p	CLIP-seq
MIRT1385935	hsa-miR-4692	CLIP-seq
MIRT2115500	hsa-miR-4700-3p	CLIP-seq
MIRT2115501	hsa-miR-4721	CLIP-seq
MIRT1385940	hsa-miR-4736	CLIP-seq
MIRT2115502	hsa-miR-4747-5p	CLIP-seq
MIRT2115503	hsa-miR-520f	CLIP-seq
MIRT2115504	hsa-miR-563	CLIP-seq
MIRT2115505	hsa-miR-612	CLIP-seq
MIRT2115506	hsa-miR-627	CLIP-seq
MIRT2115507	hsa-miR-636	CLIP-seq
MIRT2115508	hsa-miR-663	CLIP-seq
MIRT1385890	hsa-miR-1207-5p	CLIP-seq
MIRT2338123	hsa-miR-1266	CLIP-seq
MIRT2338124	hsa-miR-1972	CLIP-seq
MIRT2338125	hsa-miR-3127-5p	CLIP-seq
MIRT2338126	hsa-miR-3650	CLIP-seq
MIRT2338127	hsa-miR-3918	CLIP-seq
MIRT2338128	hsa-miR-4269	CLIP-seq
MIRT2338129	hsa-miR-4436b-3p	CLIP-seq
MIRT2338130	hsa-miR-4438	CLIP-seq
MIRT2338131	hsa-miR-4446-5p	CLIP-seq
MIRT1385919	hsa-miR-4455	CLIP-seq
MIRT2338132	hsa-miR-4518	CLIP-seq
MIRT2338133	hsa-miR-4749-3p	CLIP-seq
MIRT1385942	hsa-miR-4763-3p	CLIP-seq
MIRT2338134	hsa-miR-5095	CLIP-seq
MIRT2460483	hsa-miR-188-3p	CLIP-seq
MIRT2338127	hsa-miR-3918	CLIP-seq
MIRT2460484	hsa-miR-4685-5p	CLIP-seq
MIRT1385936	hsa-miR-4715-3p	CLIP-seq
MIRT2460485	hsa-miR-4732-3p	CLIP-seq
MIRT2460486	hsa-miR-4733-3p	CLIP-seq
MIRT2460483	hsa-miR-188-3p	CLIP-seq
MIRT2338127	hsa-miR-3918	CLIP-seq
MIRT2460484	hsa-miR-4685-5p	CLIP-seq
MIRT2460486	hsa-miR-4733-3p	CLIP-seq
MIRT2631735	hsa-miR-1225-3p	CLIP-seq
MIRT2631736	hsa-miR-1233	CLIP-seq
MIRT2631737	hsa-miR-1291	CLIP-seq
MIRT2631738	hsa-miR-148a	CLIP-seq
MIRT2631739	hsa-miR-148b	CLIP-seq
MIRT2631740	hsa-miR-152	CLIP-seq
MIRT2631741	hsa-miR-3907	CLIP-seq
MIRT2338127	hsa-miR-3918	CLIP-seq
MIRT2631742	hsa-miR-4264	CLIP-seq
MIRT2631743	hsa-miR-4641	CLIP-seq
MIRT2631744	hsa-miR-4663	CLIP-seq
MIRT2460484	hsa-miR-4685-5p	CLIP-seq
MIRT2460486	hsa-miR-4733-3p	CLIP-seq
MIRT2631745	hsa-miR-4797-3p	CLIP-seq
MIRT2631746	hsa-miR-512-3p	CLIP-seq
MIRT2631747	hsa-miR-548q	CLIP-seq
MIRT2631735	hsa-miR-1225-3p	CLIP-seq
MIRT2631736	hsa-miR-1233	CLIP-seq
MIRT2631737	hsa-miR-1291	CLIP-seq
MIRT2631738	hsa-miR-148a	CLIP-seq
MIRT2631739	hsa-miR-148b	CLIP-seq
MIRT2631740	hsa-miR-152	CLIP-seq
MIRT1385899	hsa-miR-22	CLIP-seq
MIRT2631741	hsa-miR-3907	CLIP-seq
MIRT2338127	hsa-miR-3918	CLIP-seq
MIRT2631742	hsa-miR-4264	CLIP-seq
MIRT1385924	hsa-miR-4514	CLIP-seq
MIRT2631743	hsa-miR-4641	CLIP-seq
MIRT2631744	hsa-miR-4663	CLIP-seq
MIRT2460484	hsa-miR-4685-5p	CLIP-seq
MIRT1385935	hsa-miR-4692	CLIP-seq
MIRT2460486	hsa-miR-4733-3p	CLIP-seq
MIRT2631745	hsa-miR-4797-3p	CLIP-seq
MIRT2631746	hsa-miR-512-3p	CLIP-seq
MIRT2631747	hsa-miR-548q	CLIP-seq

Gene ontology (GO) Show/Hide all (14)

GO ID	Ontology	Definition	Evidence	Reference
GO:0003676	Function	Nucleic acid binding	IBA
GO:0003676	Function	Nucleic acid binding	IEA
GO:0005576	Component	Extracellular region	TAS
GO:0005634	Component	Nucleus	IBA
GO:0005634	Component	Nucleus	IEA
GO:0005730	Component	Nucleolus	IEA
GO:0005829	Component	Cytosol	IEA
GO:0005886	Component	Plasma membrane	IEA
GO:0005886	Component	Plasma membrane	TAS
GO:0006606	Process	Protein import into nucleus	IBA
GO:0006606	Process	Protein import into nucleus	IEA
GO:0016020	Component	Membrane	IEA
GO:0031982	Component	Vesicle	IEA
GO:0098552	Component	Side of membrane	IEA

Other IDs

• MIM: 610447
• HGNC: 16871
• e!Ensembl: ENSG00000203772

Protein

• UniProt ID: Q5BIV9
• Protein name: Shadow of prion protein (Protein shadoo)
• Protein function: Prion-like protein that has PrP(C)-like neuroprotective activity. May act as a modulator for the biological actions of normal and abnormal PrP (By similarity).
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF14999	Shadoo	19 → 151	Shadow of prion protein, neuroprotective	Family

• Tissue specificity: TISSUE SPECIFICITY: Mainly expressed in brain. In brain, it is expressed in hippocampus. {ECO:0000269|PubMed:14527721}.
• Sequence:

  MNWAPATCWALLLAAAFLCDSGAAKGGRGGARGSARGGVRGGARGASRVRVRPAQRYGAP
  GSSLRVAAAGAAAGAAAGAAAGLAAGSGWRRAAGPGERGLEDEEDGVPGGNGTGPGIYSY
  RAWTSGAGPTRGPRLCLVLGGALGALGLLRP

• Sequence length: 151

Pathways

Reactome Pathway:

Post-translational modification: synthesis of GPI-anchored proteins

Related Genes

No strongly related genes found yet for SPRN.

Diseases Linked via Similar Genes

No additional diseases found yet through genes similar to SPRN.