SPIRE1 (spire type actin nucleation factor 1)

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Gene miRNA Gene ontology Other IDs Protein Related genes Diseases linked via similar genes

Gene

• Entrez ID: 56907
• Gene name: Spire type actin nucleation factor 1
• Gene symbol: SPIRE1
• Synonyms (NCBI Gene): Spir-1
• Chromosome: 18
• Chromosome location: 18p11.21
• Summary: Spire proteins, such as SPIRE1, are highly conserved between species. They belong to the family of Wiskott-Aldrich homology region-2 (WH2) proteins, which are involved in actin organization (Kerkhoff et al., 2001 [PubMed 11747823]).[supplied by OMIM, Mar

miRNA Show/Hide all (514)

miRTarBase ID	miRNA	Experiments	Reference
MIRT018998	hsa-miR-335-5p	Microarray	18185580
MIRT019528	hsa-miR-151a-5p	Sequencing	20371350
MIRT021111	hsa-miR-186-5p	Sequencing	20371350
MIRT027361	hsa-miR-101-3p	Sequencing	20371350
MIRT048628	hsa-miR-99a-5p	CLASH	23622248
MIRT042086	hsa-miR-484	CLASH	23622248
MIRT039199	hsa-miR-769-5p	CLASH	23622248
MIRT554025	hsa-miR-181b-5p	PAR-CLIP	21572407
MIRT554024	hsa-miR-4262	PAR-CLIP	21572407
MIRT554023	hsa-miR-181d-5p	PAR-CLIP	21572407
MIRT554022	hsa-miR-181a-5p	PAR-CLIP	21572407
MIRT554021	hsa-miR-181c-5p	PAR-CLIP	21572407
MIRT554020	hsa-miR-655-3p	PAR-CLIP	21572407
MIRT554019	hsa-miR-374c-5p	PAR-CLIP	21572407
MIRT554018	hsa-miR-4662a-3p	PAR-CLIP	21572407
MIRT554017	hsa-miR-510-5p	PAR-CLIP	21572407
MIRT554016	hsa-miR-3925-5p	PAR-CLIP	21572407
MIRT554015	hsa-miR-3123	PAR-CLIP	21572407
MIRT554014	hsa-miR-369-3p	PAR-CLIP	21572407
MIRT554013	hsa-miR-3976	PAR-CLIP	21572407
MIRT554012	hsa-miR-6777-3p	PAR-CLIP	21572407
MIRT554011	hsa-miR-215-3p	PAR-CLIP	21572407
MIRT439553	hsa-miR-218-5p	HITS-CLIP	23212916
MIRT439553	hsa-miR-218-5p	HITS-CLIP	23212916
MIRT554025	hsa-miR-181b-5p	PAR-CLIP	21572407
MIRT554024	hsa-miR-4262	PAR-CLIP	21572407
MIRT554023	hsa-miR-181d-5p	PAR-CLIP	21572407
MIRT554022	hsa-miR-181a-5p	PAR-CLIP	21572407
MIRT554021	hsa-miR-181c-5p	PAR-CLIP	21572407
MIRT554020	hsa-miR-655-3p	PAR-CLIP	21572407
MIRT554019	hsa-miR-374c-5p	PAR-CLIP	21572407
MIRT554018	hsa-miR-4662a-3p	PAR-CLIP	21572407
MIRT554017	hsa-miR-510-5p	PAR-CLIP	21572407
MIRT554016	hsa-miR-3925-5p	PAR-CLIP	21572407
MIRT554015	hsa-miR-3123	PAR-CLIP	21572407
MIRT554014	hsa-miR-369-3p	PAR-CLIP	21572407
MIRT554013	hsa-miR-3976	PAR-CLIP	21572407
MIRT554012	hsa-miR-6777-3p	PAR-CLIP	21572407
MIRT554011	hsa-miR-215-3p	PAR-CLIP	21572407
MIRT1384691	hsa-let-7a	CLIP-seq
MIRT1384692	hsa-let-7b	CLIP-seq
MIRT1384693	hsa-let-7c	CLIP-seq
MIRT1384694	hsa-let-7d	CLIP-seq
MIRT1384695	hsa-let-7e	CLIP-seq
MIRT1384696	hsa-let-7f	CLIP-seq
MIRT1384697	hsa-let-7g	CLIP-seq
MIRT1384698	hsa-let-7i	CLIP-seq
MIRT1384699	hsa-miR-101	CLIP-seq
MIRT1384700	hsa-miR-106a	CLIP-seq
MIRT1384701	hsa-miR-106b	CLIP-seq
MIRT1384702	hsa-miR-1179	CLIP-seq
MIRT1384703	hsa-miR-1245b-3p	CLIP-seq
MIRT1384704	hsa-miR-1266	CLIP-seq
MIRT1384705	hsa-miR-1290	CLIP-seq
MIRT1384706	hsa-miR-129-5p	CLIP-seq
MIRT1384707	hsa-miR-1304	CLIP-seq
MIRT1384708	hsa-miR-130a	CLIP-seq
MIRT1384709	hsa-miR-130b	CLIP-seq
MIRT1384710	hsa-miR-142-5p	CLIP-seq
MIRT1384711	hsa-miR-144	CLIP-seq
MIRT1384712	hsa-miR-148a	CLIP-seq
MIRT1384713	hsa-miR-148b	CLIP-seq
MIRT1384714	hsa-miR-152	CLIP-seq
MIRT1384715	hsa-miR-17	CLIP-seq
MIRT1384716	hsa-miR-193a-3p	CLIP-seq
MIRT1384717	hsa-miR-193b	CLIP-seq
MIRT1384718	hsa-miR-19a	CLIP-seq
MIRT1384719	hsa-miR-19b	CLIP-seq
MIRT1384720	hsa-miR-202	CLIP-seq
MIRT1384721	hsa-miR-2052	CLIP-seq
MIRT1384722	hsa-miR-2053	CLIP-seq
MIRT1384723	hsa-miR-20a	CLIP-seq
MIRT1384724	hsa-miR-20b	CLIP-seq
MIRT1384725	hsa-miR-2115	CLIP-seq
MIRT1384726	hsa-miR-2355-3p	CLIP-seq
MIRT1384727	hsa-miR-301a	CLIP-seq
MIRT1384728	hsa-miR-301b	CLIP-seq
MIRT1384729	hsa-miR-3152-5p	CLIP-seq
MIRT1384730	hsa-miR-3177-5p	CLIP-seq
MIRT1384731	hsa-miR-3183	CLIP-seq
MIRT1384732	hsa-miR-3609	CLIP-seq
MIRT1384733	hsa-miR-3616-5p	CLIP-seq
MIRT1384734	hsa-miR-3617	CLIP-seq
MIRT1384735	hsa-miR-3620	CLIP-seq
MIRT1384736	hsa-miR-3647-5p	CLIP-seq
MIRT1384737	hsa-miR-3666	CLIP-seq
MIRT1384738	hsa-miR-3671	CLIP-seq
MIRT1384739	hsa-miR-3680	CLIP-seq
MIRT1384740	hsa-miR-3909	CLIP-seq
MIRT1384741	hsa-miR-3942-3p	CLIP-seq
MIRT1384742	hsa-miR-4264	CLIP-seq
MIRT1384743	hsa-miR-4265	CLIP-seq
MIRT1384744	hsa-miR-4295	CLIP-seq
MIRT1384745	hsa-miR-4296	CLIP-seq
MIRT1384746	hsa-miR-4322	CLIP-seq
MIRT1384747	hsa-miR-4328	CLIP-seq
MIRT1384748	hsa-miR-4434	CLIP-seq
MIRT1384749	hsa-miR-4455	CLIP-seq
MIRT1384750	hsa-miR-4458	CLIP-seq
MIRT1384751	hsa-miR-4500	CLIP-seq
MIRT1384752	hsa-miR-4516	CLIP-seq
MIRT1384753	hsa-miR-4518	CLIP-seq
MIRT1384754	hsa-miR-452	CLIP-seq
MIRT1384755	hsa-miR-4521	CLIP-seq
MIRT1384756	hsa-miR-454	CLIP-seq
MIRT1384757	hsa-miR-4676-3p	CLIP-seq
MIRT1384758	hsa-miR-4678	CLIP-seq
MIRT1384759	hsa-miR-4693-5p	CLIP-seq
MIRT1384760	hsa-miR-4699-3p	CLIP-seq
MIRT1384761	hsa-miR-4723-3p	CLIP-seq
MIRT1384762	hsa-miR-4730	CLIP-seq
MIRT1384763	hsa-miR-4762-5p	CLIP-seq
MIRT1384764	hsa-miR-4774-3p	CLIP-seq
MIRT1384765	hsa-miR-4775	CLIP-seq
MIRT1384766	hsa-miR-4795-5p	CLIP-seq
MIRT1384767	hsa-miR-4796-3p	CLIP-seq
MIRT1384768	hsa-miR-4797-3p	CLIP-seq
MIRT1384769	hsa-miR-4798-3p	CLIP-seq
MIRT1384770	hsa-miR-487a	CLIP-seq
MIRT1384771	hsa-miR-510	CLIP-seq
MIRT1384772	hsa-miR-519d	CLIP-seq
MIRT1384773	hsa-miR-532-5p	CLIP-seq
MIRT1384774	hsa-miR-548a-5p	CLIP-seq
MIRT1384775	hsa-miR-548ab	CLIP-seq
MIRT1384776	hsa-miR-548ah	CLIP-seq
MIRT1384777	hsa-miR-548ak	CLIP-seq
MIRT1384778	hsa-miR-548b-5p	CLIP-seq
MIRT1384779	hsa-miR-548c-3p	CLIP-seq
MIRT1384780	hsa-miR-548c-5p	CLIP-seq
MIRT1384781	hsa-miR-548d-5p	CLIP-seq
MIRT1384782	hsa-miR-548g	CLIP-seq
MIRT1384783	hsa-miR-548h	CLIP-seq
MIRT1384784	hsa-miR-548i	CLIP-seq
MIRT1384785	hsa-miR-548j	CLIP-seq
MIRT1384786	hsa-miR-548n	CLIP-seq
MIRT1384787	hsa-miR-548w	CLIP-seq
MIRT1384788	hsa-miR-548y	CLIP-seq
MIRT1384789	hsa-miR-559	CLIP-seq
MIRT1384790	hsa-miR-562	CLIP-seq
MIRT1384791	hsa-miR-569	CLIP-seq
MIRT1384792	hsa-miR-573	CLIP-seq
MIRT1384793	hsa-miR-582-5p	CLIP-seq
MIRT1384794	hsa-miR-607	CLIP-seq
MIRT1384795	hsa-miR-609	CLIP-seq
MIRT1384796	hsa-miR-641	CLIP-seq
MIRT1384797	hsa-miR-656	CLIP-seq
MIRT1384798	hsa-miR-676	CLIP-seq
MIRT1384799	hsa-miR-888	CLIP-seq
MIRT1384800	hsa-miR-892b	CLIP-seq
MIRT1384801	hsa-miR-93	CLIP-seq
MIRT1384802	hsa-miR-98	CLIP-seq
MIRT2115151	hsa-miR-1225-3p	CLIP-seq
MIRT2115152	hsa-miR-1233	CLIP-seq
MIRT2115153	hsa-miR-3913-3p	CLIP-seq
MIRT2115154	hsa-miR-3943	CLIP-seq
MIRT2115155	hsa-miR-489	CLIP-seq
MIRT1384699	hsa-miR-101	CLIP-seq
MIRT1384702	hsa-miR-1179	CLIP-seq
MIRT1384706	hsa-miR-129-5p	CLIP-seq
MIRT2115156	hsa-miR-1302	CLIP-seq
MIRT1384708	hsa-miR-130a	CLIP-seq
MIRT1384709	hsa-miR-130b	CLIP-seq
MIRT1384711	hsa-miR-144	CLIP-seq
MIRT1384712	hsa-miR-148a	CLIP-seq
MIRT1384713	hsa-miR-148b	CLIP-seq
MIRT1384714	hsa-miR-152	CLIP-seq
MIRT2115157	hsa-miR-153	CLIP-seq
MIRT1384716	hsa-miR-193a-3p	CLIP-seq
MIRT1384717	hsa-miR-193b	CLIP-seq
MIRT1384718	hsa-miR-19a	CLIP-seq
MIRT1384719	hsa-miR-19b	CLIP-seq
MIRT1384726	hsa-miR-2355-3p	CLIP-seq
MIRT1384727	hsa-miR-301a	CLIP-seq
MIRT1384728	hsa-miR-301b	CLIP-seq
MIRT1384729	hsa-miR-3152-5p	CLIP-seq
MIRT1384731	hsa-miR-3183	CLIP-seq
MIRT1384737	hsa-miR-3666	CLIP-seq
MIRT1384740	hsa-miR-3909	CLIP-seq
MIRT2115153	hsa-miR-3913-3p	CLIP-seq
MIRT2115158	hsa-miR-3925-3p	CLIP-seq
MIRT2115159	hsa-miR-421	CLIP-seq
MIRT1384742	hsa-miR-4264	CLIP-seq
MIRT1384744	hsa-miR-4295	CLIP-seq
MIRT2115160	hsa-miR-4298	CLIP-seq
MIRT2115161	hsa-miR-4325	CLIP-seq
MIRT1384747	hsa-miR-4328	CLIP-seq
MIRT2115162	hsa-miR-433	CLIP-seq
MIRT2115163	hsa-miR-4424	CLIP-seq
MIRT2115164	hsa-miR-448	CLIP-seq
MIRT2115165	hsa-miR-4495	CLIP-seq
MIRT2115166	hsa-miR-450b-5p	CLIP-seq
MIRT1384755	hsa-miR-4521	CLIP-seq
MIRT1384756	hsa-miR-454	CLIP-seq
MIRT2115167	hsa-miR-4633-5p	CLIP-seq
MIRT2115168	hsa-miR-4666-3p	CLIP-seq
MIRT1384760	hsa-miR-4699-3p	CLIP-seq
MIRT2115169	hsa-miR-4709-5p	CLIP-seq
MIRT1384761	hsa-miR-4723-3p	CLIP-seq
MIRT2115170	hsa-miR-4757-3p	CLIP-seq
MIRT1384764	hsa-miR-4774-3p	CLIP-seq
MIRT1384765	hsa-miR-4775	CLIP-seq
MIRT2115171	hsa-miR-4789-5p	CLIP-seq
MIRT1384768	hsa-miR-4797-3p	CLIP-seq
MIRT2115155	hsa-miR-489	CLIP-seq
MIRT2115172	hsa-miR-507	CLIP-seq
MIRT1384773	hsa-miR-532-5p	CLIP-seq
MIRT1384782	hsa-miR-548g	CLIP-seq
MIRT2115173	hsa-miR-557	CLIP-seq
MIRT1384793	hsa-miR-582-5p	CLIP-seq
MIRT2115174	hsa-miR-603	CLIP-seq
MIRT1384794	hsa-miR-607	CLIP-seq
MIRT2115175	hsa-miR-628-3p	CLIP-seq
MIRT1384797	hsa-miR-656	CLIP-seq
MIRT1384798	hsa-miR-676	CLIP-seq
MIRT2115176	hsa-miR-889	CLIP-seq
MIRT1384800	hsa-miR-892b	CLIP-seq
MIRT1384699	hsa-miR-101	CLIP-seq
MIRT1384702	hsa-miR-1179	CLIP-seq
MIRT2337799	hsa-miR-1184	CLIP-seq
MIRT2337800	hsa-miR-1202	CLIP-seq
MIRT2337801	hsa-miR-1205	CLIP-seq
MIRT2337802	hsa-miR-122	CLIP-seq
MIRT2337803	hsa-miR-124	CLIP-seq
MIRT1384703	hsa-miR-1245b-3p	CLIP-seq
MIRT1384704	hsa-miR-1266	CLIP-seq
MIRT2337804	hsa-miR-1296	CLIP-seq
MIRT1384707	hsa-miR-1304	CLIP-seq
MIRT1384708	hsa-miR-130a	CLIP-seq
MIRT1384709	hsa-miR-130b	CLIP-seq
MIRT1384711	hsa-miR-144	CLIP-seq
MIRT1384712	hsa-miR-148a	CLIP-seq
MIRT1384713	hsa-miR-148b	CLIP-seq
MIRT1384714	hsa-miR-152	CLIP-seq
MIRT2337805	hsa-miR-1827	CLIP-seq
MIRT2337806	hsa-miR-185	CLIP-seq
MIRT1384716	hsa-miR-193a-3p	CLIP-seq
MIRT1384717	hsa-miR-193b	CLIP-seq
MIRT2337807	hsa-miR-199a-3p	CLIP-seq
MIRT2337808	hsa-miR-199b-3p	CLIP-seq
MIRT1384718	hsa-miR-19a	CLIP-seq
MIRT1384719	hsa-miR-19b	CLIP-seq
MIRT1384721	hsa-miR-2052	CLIP-seq
MIRT1384722	hsa-miR-2053	CLIP-seq
MIRT1384725	hsa-miR-2115	CLIP-seq
MIRT1384726	hsa-miR-2355-3p	CLIP-seq
MIRT2337809	hsa-miR-2909	CLIP-seq
MIRT2337810	hsa-miR-300	CLIP-seq
MIRT1384727	hsa-miR-301a	CLIP-seq
MIRT1384728	hsa-miR-301b	CLIP-seq
MIRT2337811	hsa-miR-3129-5p	CLIP-seq
MIRT2337812	hsa-miR-3140-5p	CLIP-seq
MIRT2337813	hsa-miR-3158-3p	CLIP-seq
MIRT2337814	hsa-miR-3158-5p	CLIP-seq
MIRT1384730	hsa-miR-3177-5p	CLIP-seq
MIRT1384731	hsa-miR-3183	CLIP-seq
MIRT2337815	hsa-miR-3190	CLIP-seq
MIRT2337816	hsa-miR-3194-5p	CLIP-seq
MIRT2337817	hsa-miR-329	CLIP-seq
MIRT2337818	hsa-miR-361-3p	CLIP-seq
MIRT1384735	hsa-miR-3620	CLIP-seq
MIRT2337819	hsa-miR-3622a-5p	CLIP-seq
MIRT2337820	hsa-miR-362-3p	CLIP-seq
MIRT2337821	hsa-miR-3660	CLIP-seq
MIRT1384737	hsa-miR-3666	CLIP-seq
MIRT2337822	hsa-miR-3668	CLIP-seq
MIRT2337823	hsa-miR-374c	CLIP-seq
MIRT2337824	hsa-miR-381	CLIP-seq
MIRT1384740	hsa-miR-3909	CLIP-seq
MIRT2115153	hsa-miR-3913-3p	CLIP-seq
MIRT2115158	hsa-miR-3925-3p	CLIP-seq
MIRT2337825	hsa-miR-3941	CLIP-seq
MIRT1384741	hsa-miR-3942-3p	CLIP-seq
MIRT2337826	hsa-miR-3942-5p	CLIP-seq
MIRT2337827	hsa-miR-3972	CLIP-seq
MIRT2115159	hsa-miR-421	CLIP-seq
MIRT2337828	hsa-miR-4261	CLIP-seq
MIRT1384742	hsa-miR-4264	CLIP-seq
MIRT1384743	hsa-miR-4265	CLIP-seq
MIRT2337829	hsa-miR-4270	CLIP-seq
MIRT2337830	hsa-miR-4280	CLIP-seq
MIRT2337831	hsa-miR-4282	CLIP-seq
MIRT1384744	hsa-miR-4295	CLIP-seq
MIRT1384745	hsa-miR-4296	CLIP-seq
MIRT2337832	hsa-miR-4306	CLIP-seq
MIRT2337833	hsa-miR-4307	CLIP-seq
MIRT2337834	hsa-miR-4310	CLIP-seq
MIRT1384746	hsa-miR-4322	CLIP-seq
MIRT2115161	hsa-miR-4325	CLIP-seq
MIRT1384747	hsa-miR-4328	CLIP-seq
MIRT2115163	hsa-miR-4424	CLIP-seq
MIRT2337835	hsa-miR-4440	CLIP-seq
MIRT2337836	hsa-miR-4441	CLIP-seq
MIRT2337837	hsa-miR-4445	CLIP-seq
MIRT2337838	hsa-miR-4446-3p	CLIP-seq
MIRT1384749	hsa-miR-4455	CLIP-seq
MIRT2115166	hsa-miR-450b-5p	CLIP-seq
MIRT1384753	hsa-miR-4518	CLIP-seq
MIRT2337839	hsa-miR-4526	CLIP-seq
MIRT1384756	hsa-miR-454	CLIP-seq
MIRT2337840	hsa-miR-4644	CLIP-seq
MIRT2337841	hsa-miR-4653-3p	CLIP-seq
MIRT2337842	hsa-miR-466	CLIP-seq
MIRT2115168	hsa-miR-4666-3p	CLIP-seq
MIRT2337843	hsa-miR-4672	CLIP-seq
MIRT2337844	hsa-miR-4675	CLIP-seq
MIRT1384760	hsa-miR-4699-3p	CLIP-seq
MIRT2337845	hsa-miR-4703-5p	CLIP-seq
MIRT2337846	hsa-miR-4704-3p	CLIP-seq
MIRT2337847	hsa-miR-4705	CLIP-seq
MIRT2115169	hsa-miR-4709-5p	CLIP-seq
MIRT1384761	hsa-miR-4723-3p	CLIP-seq
MIRT2337848	hsa-miR-4726-3p	CLIP-seq
MIRT1384762	hsa-miR-4730	CLIP-seq
MIRT2337849	hsa-miR-4741	CLIP-seq
MIRT2337850	hsa-miR-4766-5p	CLIP-seq
MIRT2337851	hsa-miR-4782-5p	CLIP-seq
MIRT2115171	hsa-miR-4789-5p	CLIP-seq
MIRT1384768	hsa-miR-4797-3p	CLIP-seq
MIRT2337852	hsa-miR-488	CLIP-seq
MIRT2115155	hsa-miR-489	CLIP-seq
MIRT2337853	hsa-miR-492	CLIP-seq
MIRT2337854	hsa-miR-506	CLIP-seq
MIRT2115172	hsa-miR-507	CLIP-seq
MIRT1384771	hsa-miR-510	CLIP-seq
MIRT2337855	hsa-miR-544	CLIP-seq
MIRT2337856	hsa-miR-548an	CLIP-seq
MIRT1384779	hsa-miR-548c-3p	CLIP-seq
MIRT1384782	hsa-miR-548g	CLIP-seq
MIRT2115173	hsa-miR-557	CLIP-seq
MIRT2337857	hsa-miR-579	CLIP-seq
MIRT1384793	hsa-miR-582-5p	CLIP-seq
MIRT2337858	hsa-miR-598	CLIP-seq
MIRT2115174	hsa-miR-603	CLIP-seq
MIRT1384794	hsa-miR-607	CLIP-seq
MIRT1384795	hsa-miR-609	CLIP-seq
MIRT2337859	hsa-miR-622	CLIP-seq
MIRT2337860	hsa-miR-628-5p	CLIP-seq
MIRT2337861	hsa-miR-646	CLIP-seq
MIRT2337862	hsa-miR-655	CLIP-seq
MIRT1384797	hsa-miR-656	CLIP-seq
MIRT2337863	hsa-miR-664	CLIP-seq
MIRT1384798	hsa-miR-676	CLIP-seq
MIRT2337864	hsa-miR-875-5p	CLIP-seq
MIRT1384800	hsa-miR-892b	CLIP-seq
MIRT2337865	hsa-miR-936	CLIP-seq
MIRT2337806	hsa-miR-185	CLIP-seq
MIRT2337829	hsa-miR-4270	CLIP-seq
MIRT2337832	hsa-miR-4306	CLIP-seq
MIRT1384747	hsa-miR-4328	CLIP-seq
MIRT2115163	hsa-miR-4424	CLIP-seq
MIRT2337836	hsa-miR-4441	CLIP-seq
MIRT2337840	hsa-miR-4644	CLIP-seq
MIRT2337841	hsa-miR-4653-3p	CLIP-seq
MIRT2460434	hsa-miR-140-3p	CLIP-seq
MIRT2460435	hsa-miR-4428	CLIP-seq
MIRT2460436	hsa-miR-548aa	CLIP-seq
MIRT1384699	hsa-miR-101	CLIP-seq
MIRT1384702	hsa-miR-1179	CLIP-seq
MIRT2631266	hsa-miR-1250	CLIP-seq
MIRT2631267	hsa-miR-1254	CLIP-seq
MIRT2631268	hsa-miR-1257	CLIP-seq
MIRT2631269	hsa-miR-1264	CLIP-seq
MIRT2631270	hsa-miR-1273f	CLIP-seq
MIRT2631271	hsa-miR-1275	CLIP-seq
MIRT2115156	hsa-miR-1302	CLIP-seq
MIRT1384707	hsa-miR-1304	CLIP-seq
MIRT2631272	hsa-miR-134	CLIP-seq
MIRT2631273	hsa-miR-136	CLIP-seq
MIRT2631274	hsa-miR-139-5p	CLIP-seq
MIRT2631275	hsa-miR-143	CLIP-seq
MIRT1384711	hsa-miR-144	CLIP-seq
MIRT2337805	hsa-miR-1827	CLIP-seq
MIRT2337806	hsa-miR-185	CLIP-seq
MIRT2631276	hsa-miR-188-3p	CLIP-seq
MIRT2631277	hsa-miR-1910	CLIP-seq
MIRT2631278	hsa-miR-1972	CLIP-seq
MIRT2631279	hsa-miR-2278	CLIP-seq
MIRT1384726	hsa-miR-2355-3p	CLIP-seq
MIRT2631280	hsa-miR-28-3p	CLIP-seq
MIRT2631281	hsa-miR-3116	CLIP-seq
MIRT2631282	hsa-miR-3118	CLIP-seq
MIRT2631283	hsa-miR-3121-5p	CLIP-seq
MIRT2337812	hsa-miR-3140-5p	CLIP-seq
MIRT2631284	hsa-miR-3160-3p	CLIP-seq
MIRT2631285	hsa-miR-3163	CLIP-seq
MIRT2631286	hsa-miR-3164	CLIP-seq
MIRT2337815	hsa-miR-3190	CLIP-seq
MIRT2631287	hsa-miR-340	CLIP-seq
MIRT2631288	hsa-miR-3611	CLIP-seq
MIRT2631289	hsa-miR-3614-3p	CLIP-seq
MIRT2631290	hsa-miR-3667-3p	CLIP-seq
MIRT1384739	hsa-miR-3680	CLIP-seq
MIRT2631291	hsa-miR-3684	CLIP-seq
MIRT2631292	hsa-miR-376a	CLIP-seq
MIRT2631293	hsa-miR-376b	CLIP-seq
MIRT2631294	hsa-miR-3907	CLIP-seq
MIRT2631295	hsa-miR-3914	CLIP-seq
MIRT2115158	hsa-miR-3925-3p	CLIP-seq
MIRT2631296	hsa-miR-4254	CLIP-seq
MIRT2631297	hsa-miR-4260	CLIP-seq
MIRT2337829	hsa-miR-4270	CLIP-seq
MIRT2337831	hsa-miR-4282	CLIP-seq
MIRT2631298	hsa-miR-4297	CLIP-seq
MIRT2115160	hsa-miR-4298	CLIP-seq
MIRT2631299	hsa-miR-4300	CLIP-seq
MIRT2337832	hsa-miR-4306	CLIP-seq
MIRT2337834	hsa-miR-4310	CLIP-seq
MIRT2115162	hsa-miR-433	CLIP-seq
MIRT2631300	hsa-miR-4419a	CLIP-seq
MIRT2115163	hsa-miR-4424	CLIP-seq
MIRT2337836	hsa-miR-4441	CLIP-seq
MIRT2631301	hsa-miR-4510	CLIP-seq
MIRT2631302	hsa-miR-4528	CLIP-seq
MIRT2337840	hsa-miR-4644	CLIP-seq
MIRT2631303	hsa-miR-4646-3p	CLIP-seq
MIRT2631304	hsa-miR-4650-5p	CLIP-seq
MIRT2337841	hsa-miR-4653-3p	CLIP-seq
MIRT2631305	hsa-miR-4665-5p	CLIP-seq
MIRT2115168	hsa-miR-4666-3p	CLIP-seq
MIRT2631306	hsa-miR-4708-5p	CLIP-seq
MIRT2631307	hsa-miR-4712-3p	CLIP-seq
MIRT2631308	hsa-miR-4738-3p	CLIP-seq
MIRT2115170	hsa-miR-4757-3p	CLIP-seq
MIRT2631309	hsa-miR-4770	CLIP-seq
MIRT1384769	hsa-miR-4798-3p	CLIP-seq
MIRT2631310	hsa-miR-513a-3p	CLIP-seq
MIRT2631311	hsa-miR-532-3p	CLIP-seq
MIRT1384779	hsa-miR-548c-3p	CLIP-seq
MIRT2631312	hsa-miR-574-3p	CLIP-seq
MIRT2631313	hsa-miR-576-3p	CLIP-seq
MIRT2631314	hsa-miR-617	CLIP-seq
MIRT2337859	hsa-miR-622	CLIP-seq
MIRT2631315	hsa-miR-648	CLIP-seq
MIRT1384798	hsa-miR-676	CLIP-seq
MIRT2631316	hsa-miR-758	CLIP-seq
MIRT2631317	hsa-miR-885-5p	CLIP-seq
MIRT2115176	hsa-miR-889	CLIP-seq
MIRT2631318	hsa-miR-920	CLIP-seq
MIRT2631319	hsa-miR-934	CLIP-seq
MIRT2691879	hsa-miR-10a	CLIP-seq
MIRT2691880	hsa-miR-10b	CLIP-seq
MIRT2631266	hsa-miR-1250	CLIP-seq
MIRT2631267	hsa-miR-1254	CLIP-seq
MIRT2631268	hsa-miR-1257	CLIP-seq
MIRT2631269	hsa-miR-1264	CLIP-seq
MIRT2631270	hsa-miR-1273f	CLIP-seq
MIRT2115156	hsa-miR-1302	CLIP-seq
MIRT1384707	hsa-miR-1304	CLIP-seq
MIRT2631272	hsa-miR-134	CLIP-seq
MIRT2691881	hsa-miR-135a	CLIP-seq
MIRT2691882	hsa-miR-135b	CLIP-seq
MIRT2631275	hsa-miR-143	CLIP-seq
MIRT2337805	hsa-miR-1827	CLIP-seq
MIRT2337806	hsa-miR-185	CLIP-seq
MIRT2631278	hsa-miR-1972	CLIP-seq
MIRT2631279	hsa-miR-2278	CLIP-seq
MIRT2631280	hsa-miR-28-3p	CLIP-seq
MIRT2631281	hsa-miR-3116	CLIP-seq
MIRT2631282	hsa-miR-3118	CLIP-seq
MIRT2691883	hsa-miR-3119	CLIP-seq
MIRT2631283	hsa-miR-3121-5p	CLIP-seq
MIRT2631284	hsa-miR-3160-3p	CLIP-seq
MIRT2631286	hsa-miR-3164	CLIP-seq
MIRT2337815	hsa-miR-3190	CLIP-seq
MIRT2631288	hsa-miR-3611	CLIP-seq
MIRT2631289	hsa-miR-3614-3p	CLIP-seq
MIRT1384733	hsa-miR-3616-5p	CLIP-seq
MIRT1384736	hsa-miR-3647-5p	CLIP-seq
MIRT2631290	hsa-miR-3667-3p	CLIP-seq
MIRT2337822	hsa-miR-3668	CLIP-seq
MIRT1384739	hsa-miR-3680	CLIP-seq
MIRT2631294	hsa-miR-3907	CLIP-seq
MIRT2691884	hsa-miR-3911	CLIP-seq
MIRT2631295	hsa-miR-3914	CLIP-seq
MIRT2115158	hsa-miR-3925-3p	CLIP-seq
MIRT2631296	hsa-miR-4254	CLIP-seq
MIRT2337828	hsa-miR-4261	CLIP-seq
MIRT2337829	hsa-miR-4270	CLIP-seq
MIRT2631298	hsa-miR-4297	CLIP-seq
MIRT2115160	hsa-miR-4298	CLIP-seq
MIRT2631299	hsa-miR-4300	CLIP-seq
MIRT2337832	hsa-miR-4306	CLIP-seq
MIRT2115162	hsa-miR-433	CLIP-seq
MIRT2631300	hsa-miR-4419a	CLIP-seq
MIRT2115163	hsa-miR-4424	CLIP-seq
MIRT2337836	hsa-miR-4441	CLIP-seq
MIRT2631301	hsa-miR-4510	CLIP-seq
MIRT2337840	hsa-miR-4644	CLIP-seq
MIRT2631304	hsa-miR-4650-5p	CLIP-seq
MIRT2337841	hsa-miR-4653-3p	CLIP-seq
MIRT2115168	hsa-miR-4666-3p	CLIP-seq
MIRT2631306	hsa-miR-4708-5p	CLIP-seq
MIRT2631307	hsa-miR-4712-3p	CLIP-seq
MIRT2691885	hsa-miR-4729	CLIP-seq
MIRT2115170	hsa-miR-4757-3p	CLIP-seq
MIRT1384763	hsa-miR-4762-5p	CLIP-seq
MIRT2631309	hsa-miR-4770	CLIP-seq
MIRT2691886	hsa-miR-4786-5p	CLIP-seq
MIRT1384766	hsa-miR-4795-5p	CLIP-seq
MIRT1384769	hsa-miR-4798-3p	CLIP-seq
MIRT1384792	hsa-miR-573	CLIP-seq
MIRT2631312	hsa-miR-574-3p	CLIP-seq
MIRT2631313	hsa-miR-576-3p	CLIP-seq
MIRT2691887	hsa-miR-595	CLIP-seq
MIRT2631314	hsa-miR-617	CLIP-seq
MIRT2691888	hsa-miR-624	CLIP-seq
MIRT2631315	hsa-miR-648	CLIP-seq
MIRT1384798	hsa-miR-676	CLIP-seq
MIRT2631316	hsa-miR-758	CLIP-seq
MIRT2691889	hsa-miR-873	CLIP-seq
MIRT1384799	hsa-miR-888	CLIP-seq
MIRT2631318	hsa-miR-920	CLIP-seq
MIRT2631319	hsa-miR-934	CLIP-seq
MIRT2691890	hsa-miR-944	CLIP-seq

Gene ontology (GO) Show/Hide all (42)

GO ID	Ontology	Definition	Evidence	Reference
GO:0002376	Process	Immune system process	IEA
GO:0003779	Function	Actin binding	IEA
GO:0005515	Function	Protein binding	IPI	32296183, 32814053
GO:0005654	Component	Nucleoplasm	IDA
GO:0005737	Component	Cytoplasm	IEA
GO:0005741	Component	Mitochondrial outer membrane	IDA	26305500
GO:0005829	Component	Cytosol	IDA
GO:0005856	Component	Cytoskeleton	IEA
GO:0005886	Component	Plasma membrane	IEA
GO:0005938	Component	Cell cortex	IBA
GO:0005938	Component	Cell cortex	ISS
GO:0008017	Function	Microtubule binding	IBA
GO:0015031	Process	Protein transport	IEA
GO:0016020	Component	Membrane	IEA
GO:0016192	Process	Vesicle-mediated transport	IEA
GO:0016192	Process	Vesicle-mediated transport	ISS
GO:0030036	Process	Actin cytoskeleton organization	IMP	21620703
GO:0030659	Component	Cytoplasmic vesicle membrane	IBA
GO:0030659	Component	Cytoplasmic vesicle membrane	IEA
GO:0030659	Component	Cytoplasmic vesicle membrane	ISS
GO:0031410	Component	Cytoplasmic vesicle	IEA
GO:0032154	Component	Cleavage furrow	ISS
GO:0036089	Process	Cleavage furrow formation	IBA
GO:0036089	Process	Cleavage furrow formation	ISS
GO:0040038	Process	Polar body extrusion after meiotic divisions	IBA
GO:0040038	Process	Polar body extrusion after meiotic divisions	ISS
GO:0045010	Process	Actin nucleation	IEA
GO:0045087	Process	Innate immune response	IEA
GO:0046907	Process	Intracellular transport	IBA
GO:0046907	Process	Intracellular transport	ISS
GO:0048193	Process	Golgi vesicle transport	IBA
GO:0048471	Component	Perinuclear region of cytoplasm	IEA
GO:0051295	Process	Establishment of meiotic spindle localization	IBA
GO:0051295	Process	Establishment of meiotic spindle localization	IEA
GO:0051295	Process	Establishment of meiotic spindle localization	IMP	21620703
GO:0051639	Process	Actin filament network formation	IBA
GO:0070649	Process	Formin-nucleated actin cable assembly	IEA
GO:0070649	Process	Formin-nucleated actin cable assembly	IMP	26287480
GO:0070649	Process	Formin-nucleated actin cable assembly	ISS
GO:0090141	Process	Positive regulation of mitochondrial fission	IMP	26305500
GO:2000781	Process	Positive regulation of double-strand break repair	IEA
GO:2000781	Process	Positive regulation of double-strand break repair	IMP	26287480

Other IDs

• MIM: 609216
• HGNC: 30622
• e!Ensembl: ENSG00000134278

Protein

• UniProt ID: Q08AE8
• Protein name: Protein spire homolog 1 (Spir-1)
• Protein function: Acts as an actin nucleation factor, remains associated with the slow-growing pointed end of the new filament (PubMed:11747823, PubMed:21620703). Involved in intracellular vesicle transport along actin fibers, providing a novel link between actin
• PDB: 2YLE , 2YLF , 3R7G , 3RBW
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF16474	KIND	40 → 236	Kinase non-catalytic C-lobe domain	Domain

• Sequence:

  MAQAAGPAGGGEPRTEAVGGEGPREPGAAGGAAGGSRDALSLEEILRLYNQPINEEQAWA
  VCYQCCGSLRAAARRRQPRHRVRSAAQIRVWRDGAVTLAPAADDAGEPPPVAGKLGYSQC
  METEVIESLGIIIYKALDYGLKENEERELSPPLEQLIDHMANTVEADGSNDEGYEAAEEG
  LGDEDEKRKISAIRSYRDVMKLCAAHLPTESDAPNHYQAVCRALFAETMELHTFLTKIKS
  AKENLKKIQEMEKSDESSTDLEELKNADWARFWVQVMRDLRNGVKLKKVQERQYNPLPIE
  YQLTPYEMLMDDIRCKRYTLRKVMVNGDIPPRLKKSAHEIILDFIRSRPPLNPVSARKLK
  PTPPRPRSLHERILEEIKAERKLRPVSPEEIRRSRLAMRPLSMSYSFDLSDVTTPESTKN
  LVESSMVNGGLTSQTKENGLSTSQQVPAQRKKLLRAPTLAELDSSESEEETLHKSTSSSS
  VSPSFPEEPVLEAVSTRKKPPKFLPISSTPQPERRQPPQRRHSIEKETPTNVRQFLPPSR
  QSSRSLEEFCYPVECLALTVEEVMHIRQVLVKAELEKYQQYKDIYTALKKGKLCFCCRTR
  RFSFFTWSYTCQFCKRPVCSQCCKKMRLPSKPYSTLPIFSLGPSALQRGESSMRSEKPST
  AHHRPLRSIARFSSKSKSMDKSDEELQFPKELMEDWSTMEVCVDCKKFISEIISSSRRSL
  VLANKRARLKRKTQSFYMSSPGPSEYCPSERTISEI

• Sequence length: 756

Related Genes

No strongly related genes found yet for SPIRE1.

Diseases Linked via Similar Genes

No additional diseases found yet through genes similar to SPIRE1.