SORBS1 (sorbin and SH3 domain containing 1)

Gene

• Entrez ID: 10580
• Gene name: Sorbin and SH3 domain containing 1
• Gene symbol: SORBS1
• Synonyms (NCBI Gene): CAP, FLAF2, R85FL, SH3D5, SH3P12, SORB1
• Chromosome: 10
• Chromosome location: 10q24.1
• Summary: This gene encodes a CBL-associated protein which functions in the signaling and stimulation of insulin. Mutations in this gene may be associated with human disorders of insulin resistance. Alternative splicing results in multiple transcript variants. [pro

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT044804	hsa-miR-320a	CLASH	23622248
MIRT755733	hsa-miR-503-5p	Luciferase reporter assay, Western blotting, Microarray, qRT-PCR, Immunoprecipitaion (IP), Immunohistochemistry (IHC), Immunofluorescence, Flow cytometry	34746123
MIRT1379477	hsa-miR-129-5p	CLIP-seq
MIRT1379478	hsa-miR-3674	CLIP-seq
MIRT1379479	hsa-miR-802	CLIP-seq
MIRT1379480	hsa-miR-3185	CLIP-seq
MIRT1379481	hsa-miR-3609	CLIP-seq
MIRT1379482	hsa-miR-548ah	CLIP-seq
MIRT1379483	hsa-miR-548n	CLIP-seq
MIRT1379484	hsa-miR-548t	CLIP-seq
MIRT1379485	hsa-miR-610	CLIP-seq
MIRT1379486	hsa-miR-654-3p	CLIP-seq
MIRT1379487	hsa-miR-656	CLIP-seq
MIRT1379488	hsa-miR-1291	CLIP-seq
MIRT1379489	hsa-miR-1324	CLIP-seq
MIRT1379490	hsa-miR-2467-5p	CLIP-seq
MIRT1379491	hsa-miR-3173-5p	CLIP-seq
MIRT1379492	hsa-miR-3188	CLIP-seq
MIRT1379493	hsa-miR-3194-3p	CLIP-seq
MIRT1379494	hsa-miR-3975	CLIP-seq
MIRT1379495	hsa-miR-4255	CLIP-seq
MIRT1379496	hsa-miR-4316	CLIP-seq
MIRT1379497	hsa-miR-450b-3p	CLIP-seq
MIRT1379498	hsa-miR-4642	CLIP-seq
MIRT1379499	hsa-miR-4662a-3p	CLIP-seq
MIRT1379500	hsa-miR-4712-3p	CLIP-seq
MIRT1379501	hsa-miR-4720-5p	CLIP-seq
MIRT1379502	hsa-miR-4753-5p	CLIP-seq
MIRT1379503	hsa-miR-4799-3p	CLIP-seq
MIRT1379504	hsa-miR-485-5p	CLIP-seq
MIRT1379505	hsa-miR-570	CLIP-seq
MIRT1379506	hsa-miR-769-3p	CLIP-seq
MIRT2113309	hsa-miR-4291	CLIP-seq
MIRT2113310	hsa-miR-4666-3p	CLIP-seq
MIRT2336411	hsa-miR-1200	CLIP-seq
MIRT2336411	hsa-miR-1200	CLIP-seq
MIRT2442687	hsa-miR-146a	CLIP-seq
MIRT2442688	hsa-miR-146b-5p	CLIP-seq
MIRT2442689	hsa-miR-3074-5p	CLIP-seq
MIRT2442690	hsa-miR-3124-3p	CLIP-seq
MIRT2442691	hsa-miR-34a	CLIP-seq
MIRT2442692	hsa-miR-34c-5p	CLIP-seq
MIRT2442693	hsa-miR-3677-5p	CLIP-seq
MIRT2442694	hsa-miR-4251	CLIP-seq
MIRT2442695	hsa-miR-4324	CLIP-seq
MIRT2442696	hsa-miR-4460	CLIP-seq
MIRT2442697	hsa-miR-449a	CLIP-seq
MIRT2442698	hsa-miR-449b	CLIP-seq
MIRT2442699	hsa-miR-4727-3p	CLIP-seq
MIRT2442700	hsa-miR-544b	CLIP-seq
MIRT2442701	hsa-miR-589	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0001725	Component	Stress fiber	ISS
GO:0003779	Function	Actin binding	TAS	10085297
GO:0005158	Function	Insulin receptor binding	IDA	11374898
GO:0005515	Function	Protein binding	IPI	11371513, 11374898, 12504111, 16374509, 17500595, 19116150, 23892081, 31413325, 32296183
GO:0005634	Component	Nucleus	IBA
GO:0005634	Component	Nucleus	IDA	11371513
GO:0005634	Component	Nucleus	IEA
GO:0005737	Component	Cytoplasm	IBA
GO:0005737	Component	Cytoplasm	IEA
GO:0005813	Component	Centrosome	IDA
GO:0005829	Component	Cytosol	ISS	9447983
GO:0005829	Component	Cytosol	TAS
GO:0005856	Component	Cytoskeleton	IEA
GO:0005886	Component	Plasma membrane	IDA
GO:0005886	Component	Plasma membrane	IEA
GO:0005912	Component	Adherens junction	IEA
GO:0005912	Component	Adherens junction	ISS
GO:0005912	Component	Adherens junction	TAS	10085297
GO:0005915	Component	Zonula adherens	TAS	10085297
GO:0005925	Component	Focal adhesion	IDA
GO:0005925	Component	Focal adhesion	IEA
GO:0007160	Process	Cell-matrix adhesion	TAS	10085297
GO:0008092	Function	Cytoskeletal protein binding	TAS	10085297
GO:0008286	Process	Insulin receptor signaling pathway	ISS
GO:0016020	Component	Membrane	IEA
GO:0016363	Component	Nuclear matrix	IEA
GO:0016600	Component	Flotillin complex	ISS	11001060
GO:0030055	Component	Cell-substrate junction	IBA
GO:0030055	Component	Cell-substrate junction	ISS
GO:0030159	Function	Signaling receptor complex adaptor activity	IDA	11374898
GO:0030159	Function	Signaling receptor complex adaptor activity	ISS	9447983
GO:0031589	Process	Cell-substrate adhesion	IBA
GO:0032869	Process	Cellular response to insulin stimulus	ISS	11001060
GO:0043149	Process	Stress fiber assembly	ISS
GO:0045121	Component	Membrane raft	ISS
GO:0045725	Process	Positive regulation of glycogen biosynthetic process	ISS	11001060
GO:0046326	Process	Positive regulation of D-glucose import	ISS	11001060
GO:0046628	Process	Positive regulation of insulin receptor signaling pathway	ISS
GO:0046889	Process	Positive regulation of lipid biosynthetic process	ISS	11001060
GO:0048041	Process	Focal adhesion assembly	ISS
GO:0070161	Component	Anchoring junction	IEA
GO:1903078	Process	Positive regulation of protein localization to plasma membrane	ISS

Other IDs

• MIM: 605264
• HGNC: 14565
• e!Ensembl: ENSG00000095637

Protein

• UniProt ID: Q9BX66
• Protein name: Sorbin and SH3 domain-containing protein 1 (Ponsin) (SH3 domain protein 5) (SH3P12) (c-Cbl-associated protein) (CAP)
• Protein function: Plays a role in tyrosine phosphorylation of CBL by linking CBL to the insulin receptor. Required for insulin-stimulated glucose transport. Involved in formation of actin stress fibers and focal adhesions (By similarity). {ECO:0000250|UniProtKB:Q
• PDB: 2DL3, 2ECZ, 2LJ0, 2LJ1, 2MOX, 2O2W, 2O31, 2O9S, 2O9V, 4LN2, 4LNP
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF02208	Sorb	370 → 411	Sorbin homologous domain	Family
  PF07653	SH3_2	797 → 850	Variant SH3 domain	Domain
  PF00018	SH3_1	873 → 920	SH3 domain	Domain
  PF14604	SH3_9	1238 → 1288	Variant SH3 domain	Domain

• Tissue specificity: TISSUE SPECIFICITY: Detected in skeletal muscle (at protein level). Widely expressed with highest levels in heart and skeletal muscle. {ECO:0000269|PubMed:11374898, ECO:0000269|PubMed:17462669}.
• Sequence:

  MSSECDGGSKAVMNGLAPGSNGQDKATADPLRARSISAVKIIPVKTVKNASGLVLPTDMD
  LTKICTGKGAVTLRASSSYRETPSSSPASPQETRQHESKPGLEPEPSSADEWRLSSSADA
  NGNAQPSSLAAKGYRSVHPNLPSDKSQDATSSSAAQPEVIVVPLYLVNTDRGQEGTARPP
  TPLGPLGCVPTIPATASAASPLTFPTLDDFIPPHLQRWPHHSQPARASGSFAPISQTPPS
  FSPPPPLVPPAPEDLRRVSEPDLTGAVSSTDSSPLLNEVSSSLIGTDSQAFPSVSKPSSA
  YPSTTIVNPTIVLLQHNREQQKRLSSLSDPVSERRVGEQDSAPTQEKPTSPGKAIEKRAK
  DDSRRVVKSTQDLSDVSMDEVGIPLRNTERSKDWYKTMFKQIHKLNRDTPEENPYFPTYK
  FPELPEIQQTSEEDNPYTPTYQFPASTPSPKSEDDDSDLYSPRYSFSEDTKSPLSVPRSK
  SEMSYIDGEKVVKRSATLPLPARSSSLKSSSERNDWEPPDKKVDTRKYRAEPKSIYEYQP
  GKSSVLTNEKMSRDISPEEIDLKNEPWYKFFSELEFGKPPPKKIWDYTPGDCSILPREDR
  KTNLDKDLSLCQTELEADLEKMETLNKAPSANVPQSSAISPTPEISSETPGYIYSSNFHA
  VKRESDGAPGDLTSLENERQIYKSVLEGGDIPLQGLSGLKRPSSSASTKDSESPRHFIPA
  DYLESTEEFIRRRHDDKEKLLADQRRLKREQEEADIAARRHTGVIPTHHQFITNERFGDL
  LNIDDTAKRKSGSEMRPARAKFDFKAQTLKELPLQKGDIVYIYKQIDQNWYEGEHHGRVG
  IFPRTYIELLPPAEKAQPKKLTPVQVLEYGEAIAKFNFNGDTQVEMSFRKGERITLLRQV
  DENWYEGRIPGTSRQGIFPITYVDVIKRPLVKNPVDYMDLPFSSSPSRSATASPQFSSHS
  KLITPAPSSLPHSRRALSPEMHAVTSEWISLTVGVPGRRSLALTPPLPPLPEASIYNTDH
  LALSPRASPSLSLSLPHLSWSDRPTPRSVASPLALPSPHKTYSLAPTSQASLHMNGDGGV
  HTPSSGIHQDSFLQLPLGSSDSVISQLSDAFSSQSKRQPWREESGQYERKAERGAGERGP
  GGPKISKKSCLKPSDVVRCLSTEQRLSDLNTPEESRPGKPLGSAFPGSEAEQTERHRGGE
  QAGRKAARRGGSQQPQAQQRRVTPDRSQTSQDLFSYQALYSYIPQNDDELELRDGDIVDV
  MEKCDDGWFVGTSRRTKQFGTFPGNYVKPLYL

• Sequence length: 1292

Associated diseases

Evidence Score:

• ★☆☆☆☆  Gene-disease association found in Text Mining only
• ★★☆☆☆  Found in Text Mining and Unknown/Other Associations
• ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources
• ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
• ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Unknown / Other Associations
Phenotype Name	Clinical Significance	Source	Evidence Score
ATRIAL FIBRILLATION	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
AUTISM SPECTRUM DISORDER	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
CARDIOVASCULAR DISEASE	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
DIABETES MELLITUS, NON-INSULIN-DEPENDENT	—	Disgenet	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
DIABETIC NEPHROPATHY	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
DIVERTICULAR DISEASE	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
HYPERTENSION	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Lung cancer	Benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
MENTAL OR BEHAVIOURAL DISORDER	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
METABOLIC SYNDROME	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
MIGRAINE DISORDER	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
OBESITY	—	Disgenet, GWAS catalog Disgenet, GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Prostate cancer	Uncertain significance	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
SARCOIDOSIS	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Thyroid cancer, nonmedullary, 1	Uncertain significance	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
TYPE 2 DIABETES MELLITUS	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Uterine corpus endometrial carcinoma	Benign	ClinVar	★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Associations from Text Mining
Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Acute leukemia	Leukemia	BEFREE	29456727		★☆☆☆☆ Found in Text Mining only
Allergic sensitization	Allergic Sensitization	BEFREE	28477791		★☆☆☆☆ Found in Text Mining only
Aplastic Anemia	Aplastic anemia	BEFREE	2624428		★☆☆☆☆ Found in Text Mining only
Asthma	Asthma	BEFREE	22913580		★☆☆☆☆ Found in Text Mining only
beta Thalassemia	beta Thalassemia	BEFREE	1643026		★☆☆☆☆ Found in Text Mining only
Beta thalassemia intermedia	beta Thalassemia	BEFREE	26418075		★☆☆☆☆ Found in Text Mining only
beta^+^ Thalassemia	beta Thalassemia	BEFREE	1643026		★☆☆☆☆ Found in Text Mining only
Brain Infarction	Brain Infarction	BEFREE	18394047		★☆☆☆☆ Found in Text Mining only
Breast Carcinoma	Breast Carcinoma	BEFREE	19289584, 19369627, 19864236, 24698965, 25367072, 25818873, 26473483, 26754674, 27180259, 27455837, 27791200, 28764718, 30953146, 31076089, 31732618, 31789129		★☆☆☆☆ Found in Text Mining only
Breast Neoplasms	Breast neoplasm	Pubtator	31789129	Associate	★☆☆☆☆ Found in Text Mining only
Carcinoma, Ovarian Epithelial	Ovarian Epithelial carcinoma	BEFREE	25133707		★☆☆☆☆ Found in Text Mining only
Cardiovascular Diseases	Cardiovascular disease	Pubtator	24905834	Associate	★☆☆☆☆ Found in Text Mining only
Cardiovascular Diseases	Cardiovascular Diseases	GWASCAT_DG	30595370		★☆☆☆☆ Found in Text Mining only
Cerebrovascular accident	Stroke	BEFREE	31806131		★☆☆☆☆ Found in Text Mining only
Colitis	Colitis	BEFREE	30144577		★☆☆☆☆ Found in Text Mining only
Colorectal Neoplasms	Colorectal neoplasm	Pubtator	32319594, 37164919	Associate	★☆☆☆☆ Found in Text Mining only
Congenital chromosomal disease	Congenital Chromosomal Disease	BEFREE	16368518		★☆☆☆☆ Found in Text Mining only
Dementia	Dementia	Pubtator	36421848	Associate	★☆☆☆☆ Found in Text Mining only
Diabetes	Diabetes	BEFREE	11532984, 12849814, 18394047, 30002559, 31612634		★☆☆☆☆ Found in Text Mining only
Diabetes Mellitus	Diabetes Mellitus	BEFREE	11532984, 12849814, 18394047, 30002559, 31612634		★☆☆☆☆ Found in Text Mining only
Diabetes Mellitus	Diabetes mellitus	Pubtator	12849814, 30002559	Associate	★☆☆☆☆ Found in Text Mining only
Diabetes Mellitus Type 1	Diabetes mellitus, type 1	Pubtator	25476525	Associate	★☆☆☆☆ Found in Text Mining only
Diabetes Mellitus Type 2	Diabetes mellitus, type 2	Pubtator	24403596	Stimulate	★☆☆☆☆ Found in Text Mining only
Diabetes Mellitus Type 2	Diabetes mellitus, type 2	Pubtator	26962801	Associate	★☆☆☆☆ Found in Text Mining only
Diabetes Mellitus, Insulin-Dependent	Diabetes Mellitus	GWASCAT_DG	25476525		★☆☆☆☆ Found in Text Mining only
Diabetes Mellitus, Non-Insulin-Dependent	Diabetes Mellitus	BEFREE	11532984, 28225806		★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Diabetic Nephropathies	Diabetic neuropathy	Pubtator	25476525	Associate	★☆☆☆☆ Found in Text Mining only
Diabetic Nephropathy	Diabetic Nephropathy	GWASCAT_DG	25476525		★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Endometriosis	Endometriosis	Pubtator	34409913	Associate	★☆☆☆☆ Found in Text Mining only
Epilepsy	Epilepsy	BEFREE	31638258		★☆☆☆☆ Found in Text Mining only
Epithelial ovarian cancer	Ovarian cancer	BEFREE	25133707		★☆☆☆☆ Found in Text Mining only
Essential Hypertension	Hypertension	Pubtator	26962801	Associate	★☆☆☆☆ Found in Text Mining only
Fatty Liver	Fatty Liver	BEFREE	29108123		★☆☆☆☆ Found in Text Mining only
Fibrosis, Liver	Liver Fibrosis	BEFREE	27639088		★☆☆☆☆ Found in Text Mining only
Glioblastoma	Glioblastoma	BEFREE	28555065		★☆☆☆☆ Found in Text Mining only
Glioblastoma Multiforme	Glioblastoma	BEFREE	28555065		★☆☆☆☆ Found in Text Mining only
Graves Ophthalmopathy	Graves ophthalmopathy	Pubtator	34078122	Associate	★☆☆☆☆ Found in Text Mining only
Huntington Disease	Huntington Disease	BEFREE	21858921		★☆☆☆☆ Found in Text Mining only
Hyperandrogenism	Hyperandrogenism	BEFREE	12849814		★☆☆☆☆ Found in Text Mining only
Hyperandrogenism	Hyperandrogenism	LHGDN	12849814		★☆☆☆☆ Found in Text Mining only
Hypersomnia	Hypersomnia	BEFREE	29631952		★☆☆☆☆ Found in Text Mining only
Hypertension	Hypertension	Pubtator	26962801	Associate	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Hypertensive disease	Hypertension	BEFREE	19282865, 26962801		★☆☆☆☆ Found in Text Mining only
Insulin Resistance	Diabetes mellitus, type 2	Pubtator	26962801	Associate	★☆☆☆☆ Found in Text Mining only
Ischemic stroke	Ischemic Stroke	BEFREE	18394047		★☆☆☆☆ Found in Text Mining only
Leukemia, Myelocytic, Acute	Leukemia	GWASCAT_DG	27903959		★☆☆☆☆ Found in Text Mining only
Liver carcinoma	Liver carcinoma	BEFREE	16368518, 23742296		★☆☆☆☆ Found in Text Mining only
Malignant lymphoma, lymphocytic, intermediate differentiation, diffuse	Malignant lymphoma, lymphocytic, intermediate differentiation	BEFREE	30348538		★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of breast	Breast Cancer	BEFREE	19289584, 19369627, 19864236, 24504069, 25367072, 25818873, 26223814, 26473483, 26754674, 26820945, 27180259, 27455837, 27716627, 27791200, 28764718, 30520947, 31076089, 31732618, 31789129		★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of breast	Breast Cancer	UNIPROT_DG			★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of prostate	Prostate cancer	BEFREE	28917266		★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of stomach	Stomach Neoplasms	BEFREE	29901187		★☆☆☆☆ Found in Text Mining only
Malignant Neoplasms	Malignant Neoplasm	BEFREE	24464224, 24551292, 27791200, 31837433		★☆☆☆☆ Found in Text Mining only
Mammary Neoplasms	Mammary Neoplasms	BEFREE	30241820		★☆☆☆☆ Found in Text Mining only
Mannose-Binding Protein Deficiency	Mannose-Binding Protein Deficiency	BEFREE	22523362		★☆☆☆☆ Found in Text Mining only
Mantle cell lymphoma	Mantle Cell Lymphoma	BEFREE	30348538		★☆☆☆☆ Found in Text Mining only
Motor neuron atrophy	Motor neuron atrophy	BEFREE	19279216		★☆☆☆☆ Found in Text Mining only
Muscular Dystrophies, Limb-Girdle	Limb-Girdle Muscular Dystrophy	BEFREE	30564623		★☆☆☆☆ Found in Text Mining only
Neoplasms	Neoplasms	BEFREE	10440809, 27180259, 27791200, 28032917, 28192599, 30520947, 31375912		★☆☆☆☆ Found in Text Mining only
Non-alcoholic Fatty Liver Disease	Non-Alcoholic Fatty Liver Disease	BEFREE	29108123		★☆☆☆☆ Found in Text Mining only
Obesity	Obesity	BEFREE	11532984, 12849814, 24905834		★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Obesity	Obesity	Pubtator	12690089, 12849814, 24905834, 26962801	Associate	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Osteosarcoma	Osteosarcoma	BEFREE	30286779		★☆☆☆☆ Found in Text Mining only
Paroxysmal nocturnal hemoglobinuria	Paroxysmal nocturnal hemoglobinuria	BEFREE	23402025		★☆☆☆☆ Found in Text Mining only
Perry Syndrome	Perry Syndrome	BEFREE	19136952, 20518521		★☆☆☆☆ Found in Text Mining only
Pleural effusion disorder	Pleural effusion	BEFREE	31774020		★☆☆☆☆ Found in Text Mining only
Polycystic Ovary Syndrome	Polycystic Ovary Syndrome	BEFREE	12849814		★☆☆☆☆ Found in Text Mining only
Polycystic Ovary Syndrome	Polycystic Ovary Syndrome	LHGDN	12849814		★☆☆☆☆ Found in Text Mining only
Precocious pubarche	Precocious Pubarche	BEFREE	12849814		★☆☆☆☆ Found in Text Mining only
Prostate carcinoma	Prostate cancer	BEFREE	28917266		★☆☆☆☆ Found in Text Mining only
Prostatic Neoplasms	Prostatic Neoplasms	BEFREE	31303963		★☆☆☆☆ Found in Text Mining only
Prostatic Neoplasms	Prostatic neoplasm	Pubtator	34860853	Associate	★☆☆☆☆ Found in Text Mining only
Pulmonary Disease Chronic Obstructive	Chronic obstructive pulmonary disease	Pubtator	31937552	Associate	★☆☆☆☆ Found in Text Mining only
Schizophrenia	Schizophrenia	LHGDN	19165527		★☆☆☆☆ Found in Text Mining only
Spinocerebellar Ataxias	Spinocerebellar ataxia	Pubtator	23892081	Associate	★☆☆☆☆ Found in Text Mining only
Steatohepatitis	Fatty Liver	BEFREE	29108123, 29463916, 31295293, 31377187, 31807383		★☆☆☆☆ Found in Text Mining only
Stomach Carcinoma	Stomach Carcinoma	BEFREE	29901187		★☆☆☆☆ Found in Text Mining only
Thymic Carcinoma	Thymic Carcinoma	BEFREE	30527189		★☆☆☆☆ Found in Text Mining only
Thymoma	Thymoma	BEFREE	30527189		★☆☆☆☆ Found in Text Mining only
Urinary Bladder Neoplasms	Urinary bladder neoplasms	Pubtator	36854874	Inhibit	★☆☆☆☆ Found in Text Mining only