SOCS6 (suppressor of cytokine signaling 6)

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Gene miRNA Gene ontology Other IDs Protein Pathways Related genes Diseases linked via similar genes

Gene

• Entrez ID: 9306
• Gene name: Suppressor of cytokine signaling 6
• Gene symbol: SOCS6
• Synonyms (NCBI Gene): CIS-4, CIS4, HSPC060, SOCS-4, SOCS-6, SOCS4, SSI4, STAI4, STATI4
• Chromosome: 18
• Chromosome location: 18q22.2
• Summary: The protein encoded by this gene contains a SH2 domain and a CIS homolog domain. The protein thus belongs to the cytokine-induced STAT inhibitor (CIS), also known as suppressor of cytokine signaling (SOCS) or STAT-induced STAT inhibitor (SSI), protein fam

miRNA Show/Hide all (416)

miRTarBase ID	miRNA	Experiments	Reference
MIRT006856	hsa-miR-203a-3p	Luciferase reporter assay	22917968
MIRT006856	hsa-miR-203a-3p	Luciferase reporter assay	22917968
MIRT046359	hsa-miR-23b-3p	CLASH	23622248
MIRT053149	hsa-miR-424-5p	Luciferase reporter assay, Western blot	23653113
MIRT053149	hsa-miR-424-5p	Luciferase reporter assay, Western blot	23653113
MIRT053770	hsa-miR-17-5p	Luciferase reporter assay, qRT-PCR, Western blot	24801601
MIRT053770	hsa-miR-17-5p	Luciferase reporter assay, qRT-PCR, Western blot	24801601
MIRT438140	hsa-miR-431-5p	qRT-PCR	24584142
MIRT438140	hsa-miR-431-5p	qRT-PCR	24584142
MIRT713207	hsa-miR-216b-5p	HITS-CLIP	19536157
MIRT713206	hsa-miR-665	HITS-CLIP	19536157
MIRT713205	hsa-miR-766-3p	HITS-CLIP	19536157
MIRT713204	hsa-miR-3925-3p	HITS-CLIP	19536157
MIRT713203	hsa-miR-6755-3p	HITS-CLIP	19536157
MIRT291140	hsa-miR-374a-5p	HITS-CLIP	19536157
MIRT291141	hsa-miR-374b-5p	HITS-CLIP	19536157
MIRT713202	hsa-miR-6818-3p	HITS-CLIP	19536157
MIRT713207	hsa-miR-216b-5p	HITS-CLIP	19536157
MIRT713206	hsa-miR-665	HITS-CLIP	19536157
MIRT713205	hsa-miR-766-3p	HITS-CLIP	19536157
MIRT713204	hsa-miR-3925-3p	HITS-CLIP	19536157
MIRT713203	hsa-miR-6755-3p	HITS-CLIP	19536157
MIRT291140	hsa-miR-374a-5p	HITS-CLIP	19536157
MIRT291141	hsa-miR-374b-5p	HITS-CLIP	19536157
MIRT713202	hsa-miR-6818-3p	HITS-CLIP	19536157
MIRT1378940	hsa-miR-106a	CLIP-seq
MIRT1378941	hsa-miR-106b	CLIP-seq
MIRT1378942	hsa-miR-1236	CLIP-seq
MIRT1378943	hsa-miR-128	CLIP-seq
MIRT1378944	hsa-miR-130a	CLIP-seq
MIRT1378945	hsa-miR-130b	CLIP-seq
MIRT1378946	hsa-miR-155	CLIP-seq
MIRT1378947	hsa-miR-15a	CLIP-seq
MIRT1378948	hsa-miR-15b	CLIP-seq
MIRT1378949	hsa-miR-16	CLIP-seq
MIRT1378950	hsa-miR-17	CLIP-seq
MIRT1378951	hsa-miR-1909	CLIP-seq
MIRT1378952	hsa-miR-192	CLIP-seq
MIRT1378953	hsa-miR-195	CLIP-seq
MIRT1378954	hsa-miR-203	CLIP-seq
MIRT1378955	hsa-miR-20a	CLIP-seq
MIRT1378956	hsa-miR-20b	CLIP-seq
MIRT1378957	hsa-miR-21	CLIP-seq
MIRT1378958	hsa-miR-2116	CLIP-seq
MIRT1378959	hsa-miR-215	CLIP-seq
MIRT1378960	hsa-miR-216b	CLIP-seq
MIRT1378961	hsa-miR-218	CLIP-seq
MIRT1378962	hsa-miR-27a	CLIP-seq
MIRT1378963	hsa-miR-27b	CLIP-seq
MIRT1378964	hsa-miR-300	CLIP-seq
MIRT1378965	hsa-miR-301a	CLIP-seq
MIRT1378966	hsa-miR-301b	CLIP-seq
MIRT1378967	hsa-miR-3140-3p	CLIP-seq
MIRT1378968	hsa-miR-3169	CLIP-seq
MIRT1378969	hsa-miR-337-3p	CLIP-seq
MIRT1378970	hsa-miR-3657	CLIP-seq
MIRT1378971	hsa-miR-3666	CLIP-seq
MIRT1378972	hsa-miR-3675-3p	CLIP-seq
MIRT1378973	hsa-miR-3681	CLIP-seq
MIRT1378974	hsa-miR-3685	CLIP-seq
MIRT1378975	hsa-miR-374a	CLIP-seq
MIRT1378976	hsa-miR-374b	CLIP-seq
MIRT1378977	hsa-miR-380	CLIP-seq
MIRT1378978	hsa-miR-381	CLIP-seq
MIRT1378979	hsa-miR-384	CLIP-seq
MIRT1378980	hsa-miR-3929	CLIP-seq
MIRT1378981	hsa-miR-3938	CLIP-seq
MIRT1378982	hsa-miR-424	CLIP-seq
MIRT1378983	hsa-miR-4273	CLIP-seq
MIRT1378984	hsa-miR-4295	CLIP-seq
MIRT1378985	hsa-miR-4419b	CLIP-seq
MIRT1378986	hsa-miR-4478	CLIP-seq
MIRT1378987	hsa-miR-4515	CLIP-seq
MIRT1378988	hsa-miR-4524	CLIP-seq
MIRT1378989	hsa-miR-454	CLIP-seq
MIRT1378990	hsa-miR-4643	CLIP-seq
MIRT1378991	hsa-miR-466	CLIP-seq
MIRT1378992	hsa-miR-4666-3p	CLIP-seq
MIRT1378993	hsa-miR-4669	CLIP-seq
MIRT1378994	hsa-miR-4676-5p	CLIP-seq
MIRT1378995	hsa-miR-4677-5p	CLIP-seq
MIRT1378996	hsa-miR-4696	CLIP-seq
MIRT1378997	hsa-miR-4742-3p	CLIP-seq
MIRT1378998	hsa-miR-4789-3p	CLIP-seq
MIRT1378999	hsa-miR-494	CLIP-seq
MIRT1379000	hsa-miR-497	CLIP-seq
MIRT1379001	hsa-miR-503	CLIP-seq
MIRT1379002	hsa-miR-513c	CLIP-seq
MIRT1379003	hsa-miR-514b-5p	CLIP-seq
MIRT1379004	hsa-miR-519a	CLIP-seq
MIRT1379005	hsa-miR-519b-3p	CLIP-seq
MIRT1379006	hsa-miR-519c-3p	CLIP-seq
MIRT1379007	hsa-miR-519d	CLIP-seq
MIRT1379008	hsa-miR-520d-5p	CLIP-seq
MIRT1379009	hsa-miR-520g	CLIP-seq
MIRT1379010	hsa-miR-520h	CLIP-seq
MIRT1379011	hsa-miR-524-5p	CLIP-seq
MIRT1379012	hsa-miR-545	CLIP-seq
MIRT1379013	hsa-miR-548a-3p	CLIP-seq
MIRT1379014	hsa-miR-548a-5p	CLIP-seq
MIRT1379015	hsa-miR-548ab	CLIP-seq
MIRT1379016	hsa-miR-548ac	CLIP-seq
MIRT1379017	hsa-miR-548ae	CLIP-seq
MIRT1379018	hsa-miR-548aj	CLIP-seq
MIRT1379019	hsa-miR-548ak	CLIP-seq
MIRT1379020	hsa-miR-548am	CLIP-seq
MIRT1379021	hsa-miR-548an	CLIP-seq
MIRT1379022	hsa-miR-548b-5p	CLIP-seq
MIRT1379023	hsa-miR-548c-3p	CLIP-seq
MIRT1379024	hsa-miR-548c-5p	CLIP-seq
MIRT1379025	hsa-miR-548d-3p	CLIP-seq
MIRT1379026	hsa-miR-548d-5p	CLIP-seq
MIRT1379027	hsa-miR-548e	CLIP-seq
MIRT1379028	hsa-miR-548f	CLIP-seq
MIRT1379029	hsa-miR-548g	CLIP-seq
MIRT1379030	hsa-miR-548h	CLIP-seq
MIRT1379031	hsa-miR-548i	CLIP-seq
MIRT1379032	hsa-miR-548j	CLIP-seq
MIRT1379033	hsa-miR-548k	CLIP-seq
MIRT1379034	hsa-miR-548l	CLIP-seq
MIRT1379035	hsa-miR-548m	CLIP-seq
MIRT1379036	hsa-miR-548w	CLIP-seq
MIRT1379037	hsa-miR-548x	CLIP-seq
MIRT1379038	hsa-miR-548y	CLIP-seq
MIRT1379039	hsa-miR-548z	CLIP-seq
MIRT1379040	hsa-miR-555	CLIP-seq
MIRT1379041	hsa-miR-559	CLIP-seq
MIRT1379042	hsa-miR-575	CLIP-seq
MIRT1379043	hsa-miR-590-5p	CLIP-seq
MIRT739917	hsa-miR-624	CLIP-seq
MIRT1379044	hsa-miR-636	CLIP-seq
MIRT1379045	hsa-miR-646	CLIP-seq
MIRT1379046	hsa-miR-93	CLIP-seq
MIRT1378943	hsa-miR-128	CLIP-seq
MIRT1378957	hsa-miR-21	CLIP-seq
MIRT1378960	hsa-miR-216b	CLIP-seq
MIRT1378961	hsa-miR-218	CLIP-seq
MIRT2113101	hsa-miR-3605-3p	CLIP-seq
MIRT2113102	hsa-miR-3678-3p	CLIP-seq
MIRT1378975	hsa-miR-374a	CLIP-seq
MIRT1378976	hsa-miR-374b	CLIP-seq
MIRT2113103	hsa-miR-3942-3p	CLIP-seq
MIRT1378990	hsa-miR-4643	CLIP-seq
MIRT1378991	hsa-miR-466	CLIP-seq
MIRT2113104	hsa-miR-4684-3p	CLIP-seq
MIRT2113105	hsa-miR-4691-5p	CLIP-seq
MIRT2113106	hsa-miR-4762-3p	CLIP-seq
MIRT2113107	hsa-miR-4778-5p	CLIP-seq
MIRT1378998	hsa-miR-4789-3p	CLIP-seq
MIRT1379043	hsa-miR-590-5p	CLIP-seq
MIRT2113108	hsa-miR-885-5p	CLIP-seq
MIRT2335928	hsa-miR-101	CLIP-seq
MIRT1378940	hsa-miR-106a	CLIP-seq
MIRT1378941	hsa-miR-106b	CLIP-seq
MIRT2335929	hsa-miR-1224-5p	CLIP-seq
MIRT2335930	hsa-miR-1256	CLIP-seq
MIRT2335931	hsa-miR-1271	CLIP-seq
MIRT2335932	hsa-miR-1272	CLIP-seq
MIRT1378943	hsa-miR-128	CLIP-seq
MIRT2335933	hsa-miR-1305	CLIP-seq
MIRT1378944	hsa-miR-130a	CLIP-seq
MIRT1378945	hsa-miR-130b	CLIP-seq
MIRT2335934	hsa-miR-144	CLIP-seq
MIRT2335935	hsa-miR-151-3p	CLIP-seq
MIRT2335936	hsa-miR-154	CLIP-seq
MIRT1378946	hsa-miR-155	CLIP-seq
MIRT1378947	hsa-miR-15a	CLIP-seq
MIRT1378948	hsa-miR-15b	CLIP-seq
MIRT1378949	hsa-miR-16	CLIP-seq
MIRT1378950	hsa-miR-17	CLIP-seq
MIRT2335937	hsa-miR-182	CLIP-seq
MIRT2335938	hsa-miR-183	CLIP-seq
MIRT2335939	hsa-miR-1908	CLIP-seq
MIRT1378951	hsa-miR-1909	CLIP-seq
MIRT1378953	hsa-miR-195	CLIP-seq
MIRT2335940	hsa-miR-208a	CLIP-seq
MIRT2335941	hsa-miR-208b	CLIP-seq
MIRT1378955	hsa-miR-20a	CLIP-seq
MIRT1378956	hsa-miR-20b	CLIP-seq
MIRT1378957	hsa-miR-21	CLIP-seq
MIRT1378958	hsa-miR-2116	CLIP-seq
MIRT1378960	hsa-miR-216b	CLIP-seq
MIRT2335942	hsa-miR-2355-5p	CLIP-seq
MIRT2335943	hsa-miR-23a	CLIP-seq
MIRT2335944	hsa-miR-23b	CLIP-seq
MIRT2335945	hsa-miR-23c	CLIP-seq
MIRT1378962	hsa-miR-27a	CLIP-seq
MIRT1378963	hsa-miR-27b	CLIP-seq
MIRT1378965	hsa-miR-301a	CLIP-seq
MIRT1378966	hsa-miR-301b	CLIP-seq
MIRT2335946	hsa-miR-3117-5p	CLIP-seq
MIRT2335947	hsa-miR-3120-3p	CLIP-seq
MIRT2335948	hsa-miR-3130-3p	CLIP-seq
MIRT2335949	hsa-miR-3132	CLIP-seq
MIRT2335950	hsa-miR-3145-5p	CLIP-seq
MIRT2335951	hsa-miR-3150b-3p	CLIP-seq
MIRT1378968	hsa-miR-3169	CLIP-seq
MIRT2335952	hsa-miR-3200-3p	CLIP-seq
MIRT2335953	hsa-miR-33a	CLIP-seq
MIRT2335954	hsa-miR-33b	CLIP-seq
MIRT2335955	hsa-miR-3622b-5p	CLIP-seq
MIRT2335956	hsa-miR-3664-5p	CLIP-seq
MIRT1378971	hsa-miR-3666	CLIP-seq
MIRT1378973	hsa-miR-3681	CLIP-seq
MIRT1378975	hsa-miR-374a	CLIP-seq
MIRT1378976	hsa-miR-374b	CLIP-seq
MIRT2335957	hsa-miR-3915	CLIP-seq
MIRT1378981	hsa-miR-3938	CLIP-seq
MIRT2335958	hsa-miR-3941	CLIP-seq
MIRT2113103	hsa-miR-3942-3p	CLIP-seq
MIRT2335959	hsa-miR-421	CLIP-seq
MIRT1378982	hsa-miR-424	CLIP-seq
MIRT1378983	hsa-miR-4273	CLIP-seq
MIRT2335960	hsa-miR-4286	CLIP-seq
MIRT2335961	hsa-miR-4289	CLIP-seq
MIRT1378984	hsa-miR-4295	CLIP-seq
MIRT2335962	hsa-miR-4426	CLIP-seq
MIRT2335963	hsa-miR-4434	CLIP-seq
MIRT2335964	hsa-miR-4462	CLIP-seq
MIRT2335965	hsa-miR-4470	CLIP-seq
MIRT2335966	hsa-miR-4486	CLIP-seq
MIRT2335967	hsa-miR-4502	CLIP-seq
MIRT2335968	hsa-miR-4504	CLIP-seq
MIRT1378987	hsa-miR-4515	CLIP-seq
MIRT2335969	hsa-miR-4516	CLIP-seq
MIRT2335970	hsa-miR-451b	CLIP-seq
MIRT2335971	hsa-miR-452	CLIP-seq
MIRT2335972	hsa-miR-4522	CLIP-seq
MIRT1378988	hsa-miR-4524	CLIP-seq
MIRT2335973	hsa-miR-4528	CLIP-seq
MIRT1378989	hsa-miR-454	CLIP-seq
MIRT2335974	hsa-miR-455-3p	CLIP-seq
MIRT1378990	hsa-miR-4643	CLIP-seq
MIRT2335975	hsa-miR-4647	CLIP-seq
MIRT2335976	hsa-miR-4659a-3p	CLIP-seq
MIRT2335977	hsa-miR-4659b-3p	CLIP-seq
MIRT1378991	hsa-miR-466	CLIP-seq
MIRT2335978	hsa-miR-4662b	CLIP-seq
MIRT2335979	hsa-miR-4672	CLIP-seq
MIRT2335980	hsa-miR-4676-3p	CLIP-seq
MIRT1378994	hsa-miR-4676-5p	CLIP-seq
MIRT2335981	hsa-miR-4677-3p	CLIP-seq
MIRT1378995	hsa-miR-4677-5p	CLIP-seq
MIRT2335982	hsa-miR-4679	CLIP-seq
MIRT2335983	hsa-miR-4689	CLIP-seq
MIRT1378996	hsa-miR-4696	CLIP-seq
MIRT2335984	hsa-miR-4709-5p	CLIP-seq
MIRT2335985	hsa-miR-4717-3p	CLIP-seq
MIRT2335986	hsa-miR-4722-3p	CLIP-seq
MIRT2335987	hsa-miR-4729	CLIP-seq
MIRT1378997	hsa-miR-4742-3p	CLIP-seq
MIRT2335988	hsa-miR-4760-3p	CLIP-seq
MIRT2335989	hsa-miR-4769-3p	CLIP-seq
MIRT2113107	hsa-miR-4778-5p	CLIP-seq
MIRT2335990	hsa-miR-4782-5p	CLIP-seq
MIRT2335991	hsa-miR-4784	CLIP-seq
MIRT2335992	hsa-miR-4786-3p	CLIP-seq
MIRT1378998	hsa-miR-4789-3p	CLIP-seq
MIRT2335993	hsa-miR-4793-3p	CLIP-seq
MIRT2335994	hsa-miR-4795-3p	CLIP-seq
MIRT2335995	hsa-miR-483-5p	CLIP-seq
MIRT2335996	hsa-miR-495	CLIP-seq
MIRT1379000	hsa-miR-497	CLIP-seq
MIRT1379001	hsa-miR-503	CLIP-seq
MIRT2335997	hsa-miR-508-5p	CLIP-seq
MIRT2335998	hsa-miR-5096	CLIP-seq
MIRT2335999	hsa-miR-513a-3p	CLIP-seq
MIRT1379002	hsa-miR-513c	CLIP-seq
MIRT2336000	hsa-miR-514	CLIP-seq
MIRT2336001	hsa-miR-514b-3p	CLIP-seq
MIRT1379003	hsa-miR-514b-5p	CLIP-seq
MIRT1379004	hsa-miR-519a	CLIP-seq
MIRT1379005	hsa-miR-519b-3p	CLIP-seq
MIRT1379006	hsa-miR-519c-3p	CLIP-seq
MIRT1379007	hsa-miR-519d	CLIP-seq
MIRT1379008	hsa-miR-520d-5p	CLIP-seq
MIRT1379009	hsa-miR-520g	CLIP-seq
MIRT1379010	hsa-miR-520h	CLIP-seq
MIRT1379011	hsa-miR-524-5p	CLIP-seq
MIRT2336002	hsa-miR-542-3p	CLIP-seq
MIRT2336003	hsa-miR-544	CLIP-seq
MIRT1379012	hsa-miR-545	CLIP-seq
MIRT1379023	hsa-miR-548c-3p	CLIP-seq
MIRT1379029	hsa-miR-548g	CLIP-seq
MIRT2336004	hsa-miR-556-3p	CLIP-seq
MIRT2336005	hsa-miR-561	CLIP-seq
MIRT1379042	hsa-miR-575	CLIP-seq
MIRT2336006	hsa-miR-582-5p	CLIP-seq
MIRT1379043	hsa-miR-590-5p	CLIP-seq
MIRT2336007	hsa-miR-628-5p	CLIP-seq
MIRT1379045	hsa-miR-646	CLIP-seq
MIRT2336008	hsa-miR-656	CLIP-seq
MIRT2336009	hsa-miR-663	CLIP-seq
MIRT1379046	hsa-miR-93	CLIP-seq
MIRT2336010	hsa-miR-96	CLIP-seq
MIRT2335946	hsa-miR-3117-5p	CLIP-seq
MIRT1378940	hsa-miR-106a	CLIP-seq
MIRT1378941	hsa-miR-106b	CLIP-seq
MIRT1378942	hsa-miR-1236	CLIP-seq
MIRT2335932	hsa-miR-1272	CLIP-seq
MIRT2335936	hsa-miR-154	CLIP-seq
MIRT1378950	hsa-miR-17	CLIP-seq
MIRT2335938	hsa-miR-183	CLIP-seq
MIRT1378952	hsa-miR-192	CLIP-seq
MIRT2335940	hsa-miR-208a	CLIP-seq
MIRT2335941	hsa-miR-208b	CLIP-seq
MIRT1378955	hsa-miR-20a	CLIP-seq
MIRT1378956	hsa-miR-20b	CLIP-seq
MIRT1378959	hsa-miR-215	CLIP-seq
MIRT1378960	hsa-miR-216b	CLIP-seq
MIRT2335942	hsa-miR-2355-5p	CLIP-seq
MIRT2630167	hsa-miR-30a	CLIP-seq
MIRT2630168	hsa-miR-30b	CLIP-seq
MIRT2630169	hsa-miR-30c	CLIP-seq
MIRT2630170	hsa-miR-30d	CLIP-seq
MIRT2630171	hsa-miR-30e	CLIP-seq
MIRT2335946	hsa-miR-3117-5p	CLIP-seq
MIRT2630172	hsa-miR-3127-5p	CLIP-seq
MIRT2335949	hsa-miR-3132	CLIP-seq
MIRT2630173	hsa-miR-3145-3p	CLIP-seq
MIRT1378969	hsa-miR-337-3p	CLIP-seq
MIRT2630174	hsa-miR-3609	CLIP-seq
MIRT2335955	hsa-miR-3622b-5p	CLIP-seq
MIRT1378972	hsa-miR-3675-3p	CLIP-seq
MIRT1378974	hsa-miR-3685	CLIP-seq
MIRT1378979	hsa-miR-384	CLIP-seq
MIRT2630175	hsa-miR-3918	CLIP-seq
MIRT2335958	hsa-miR-3941	CLIP-seq
MIRT2335960	hsa-miR-4286	CLIP-seq
MIRT2630176	hsa-miR-4436b-3p	CLIP-seq
MIRT2335967	hsa-miR-4502	CLIP-seq
MIRT2335972	hsa-miR-4522	CLIP-seq
MIRT2335974	hsa-miR-455-3p	CLIP-seq
MIRT1378990	hsa-miR-4643	CLIP-seq
MIRT1378991	hsa-miR-466	CLIP-seq
MIRT2335979	hsa-miR-4672	CLIP-seq
MIRT1378994	hsa-miR-4676-5p	CLIP-seq
MIRT2335985	hsa-miR-4717-3p	CLIP-seq
MIRT1378997	hsa-miR-4742-3p	CLIP-seq
MIRT1378998	hsa-miR-4789-3p	CLIP-seq
MIRT2630177	hsa-miR-4796-3p	CLIP-seq
MIRT2335995	hsa-miR-483-5p	CLIP-seq
MIRT2335996	hsa-miR-495	CLIP-seq
MIRT1379007	hsa-miR-519d	CLIP-seq
MIRT2630178	hsa-miR-539	CLIP-seq
MIRT1379012	hsa-miR-545	CLIP-seq
MIRT1379013	hsa-miR-548a-3p	CLIP-seq
MIRT2630179	hsa-miR-548ad	CLIP-seq
MIRT2630180	hsa-miR-548ah	CLIP-seq
MIRT1379027	hsa-miR-548e	CLIP-seq
MIRT1379028	hsa-miR-548f	CLIP-seq
MIRT1379029	hsa-miR-548g	CLIP-seq
MIRT2630181	hsa-miR-548p	CLIP-seq
MIRT1379040	hsa-miR-555	CLIP-seq
MIRT2336005	hsa-miR-561	CLIP-seq
MIRT1379042	hsa-miR-575	CLIP-seq
MIRT2630182	hsa-miR-885-3p	CLIP-seq
MIRT1379046	hsa-miR-93	CLIP-seq
MIRT1378942	hsa-miR-1236	CLIP-seq
MIRT2335930	hsa-miR-1256	CLIP-seq
MIRT2335932	hsa-miR-1272	CLIP-seq
MIRT2335935	hsa-miR-151-3p	CLIP-seq
MIRT2335936	hsa-miR-154	CLIP-seq
MIRT2335938	hsa-miR-183	CLIP-seq
MIRT1378952	hsa-miR-192	CLIP-seq
MIRT2335940	hsa-miR-208a	CLIP-seq
MIRT2335941	hsa-miR-208b	CLIP-seq
MIRT1378959	hsa-miR-215	CLIP-seq
MIRT2335942	hsa-miR-2355-5p	CLIP-seq
MIRT2630167	hsa-miR-30a	CLIP-seq
MIRT2630168	hsa-miR-30b	CLIP-seq
MIRT2630169	hsa-miR-30c	CLIP-seq
MIRT2630170	hsa-miR-30d	CLIP-seq
MIRT2630171	hsa-miR-30e	CLIP-seq
MIRT2335946	hsa-miR-3117-5p	CLIP-seq
MIRT2630172	hsa-miR-3127-5p	CLIP-seq
MIRT2335949	hsa-miR-3132	CLIP-seq
MIRT2630173	hsa-miR-3145-3p	CLIP-seq
MIRT2335955	hsa-miR-3622b-5p	CLIP-seq
MIRT1378972	hsa-miR-3675-3p	CLIP-seq
MIRT2630175	hsa-miR-3918	CLIP-seq
MIRT2335958	hsa-miR-3941	CLIP-seq
MIRT2335960	hsa-miR-4286	CLIP-seq
MIRT2691742	hsa-miR-4422	CLIP-seq
MIRT2630176	hsa-miR-4436b-3p	CLIP-seq
MIRT2335967	hsa-miR-4502	CLIP-seq
MIRT2335968	hsa-miR-4504	CLIP-seq
MIRT2335972	hsa-miR-4522	CLIP-seq
MIRT2335974	hsa-miR-455-3p	CLIP-seq
MIRT1378990	hsa-miR-4643	CLIP-seq
MIRT1378991	hsa-miR-466	CLIP-seq
MIRT2335979	hsa-miR-4672	CLIP-seq
MIRT1378994	hsa-miR-4676-5p	CLIP-seq
MIRT2335985	hsa-miR-4717-3p	CLIP-seq
MIRT1378997	hsa-miR-4742-3p	CLIP-seq
MIRT2113106	hsa-miR-4762-3p	CLIP-seq
MIRT2691743	hsa-miR-4766-5p	CLIP-seq
MIRT1378998	hsa-miR-4789-3p	CLIP-seq
MIRT2335995	hsa-miR-483-5p	CLIP-seq
MIRT1378999	hsa-miR-494	CLIP-seq
MIRT2335996	hsa-miR-495	CLIP-seq
MIRT1379008	hsa-miR-520d-5p	CLIP-seq
MIRT1379011	hsa-miR-524-5p	CLIP-seq
MIRT2630178	hsa-miR-539	CLIP-seq
MIRT1379012	hsa-miR-545	CLIP-seq
MIRT1379013	hsa-miR-548a-3p	CLIP-seq
MIRT2630179	hsa-miR-548ad	CLIP-seq
MIRT1379027	hsa-miR-548e	CLIP-seq
MIRT1379028	hsa-miR-548f	CLIP-seq
MIRT1379029	hsa-miR-548g	CLIP-seq
MIRT2630181	hsa-miR-548p	CLIP-seq
MIRT2691744	hsa-miR-548t	CLIP-seq
MIRT2336005	hsa-miR-561	CLIP-seq
MIRT1379042	hsa-miR-575	CLIP-seq
MIRT2691745	hsa-miR-767-5p	CLIP-seq
MIRT2630182	hsa-miR-885-3p	CLIP-seq

Gene ontology (GO) Show/Hide all (15)

GO ID	Ontology	Definition	Evidence	Reference
GO:0001772	Component	Immunological synapse	IDA	20007709
GO:0005515	Function	Protein binding	IPI	24728074, 25180228, 28514442, 32296183, 32814053, 33961781
GO:0005737	Component	Cytoplasm	TAS	9344848
GO:0005829	Component	Cytosol	IEA
GO:0005829	Component	Cytosol	TAS
GO:0006952	Process	Defense response	TAS	9344848
GO:0007259	Process	Cell surface receptor signaling pathway via JAK-STAT	TAS	9344848
GO:0009968	Process	Negative regulation of signal transduction	IEA
GO:0010498	Process	Proteasomal protein catabolic process	IMP	20007709
GO:0016567	Process	Protein ubiquitination	IEA
GO:0035556	Process	Intracellular signal transduction	IEA
GO:0035591	Function	Signaling adaptor activity	IBA
GO:0040008	Process	Regulation of growth	IEA
GO:0040008	Process	Regulation of growth	IEA
GO:0050868	Process	Negative regulation of T cell activation	IEA

Other IDs

• MIM: 605118
• HGNC: 16833
• e!Ensembl: ENSG00000170677

Protein

• UniProt ID: O14544
• Protein name: Suppressor of cytokine signaling 6 (SOCS-6) (Cytokine-inducible SH2 protein 4) (CIS-4) (Suppressor of cytokine signaling 4) (SOCS-4)
• Protein function: SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction. May be a substrate recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase compl
• PDB: 2VIF
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF00017	SH2	384 → 461	SH2 domain	Domain
  PF07525	SOCS_box	497 → 532	SOCS box	Domain

• Sequence:

  MKKISLKTLRKSFNLNKSKEETDFMVVQQPSLASDFGKDDSLFGSCYGKDMASCDINGED
  EKGGKNRSKSESLMGTLKRRLSAKQKSKGKAGTPSGSSADEDTFSSSSAPIVFKDVRAQR
  PIRSTSLRSHHYSPAPWPLRPTNSEETCIKMEVRVKALVHSSSPSPALNGVRKDFHDLQS
  ETTCQEQANSLKSSASHNGDLHLHLDEHVPVVIGLMPQDYIQYTVPLDEGMYPLEGSRSY
  CLDSSSPMEVSAVPPQVGGRAFPEDESQVDQDLVVAPEIFVDQSVNGLLIGTTGVMLQSP
  RAGHDDVPPLSPLLPPMQNNQIQRNFSGLTGTEAHVAESMRCHLNFDPNSAPGVARVYDS
  VQSSGPMVVTSLTEELKKLAKQGWYWGPITRWEAEGKLANVPDGSFLVRDSSDDRYLLSL
  SFRSHGKTLHTRIEHSNGRFSFYEQPDVEGHTSIVDLIEHSIRDSENGAFCYSRSRLPGS
  ATYPVRLTNPVSRFMQVRSLQYLCRFVIRQYTRIDLIQKLPLPNKMKDYLQEKHY

• Sequence length: 535

Pathways

KEGG Pathway	Reactome Pathway
JAK-STAT signaling pathway	Neddylation
Prolactin signaling pathway

Related Genes

Sort by: Blended Diseases Pathways Evidence source

CISH 3 shared pathwaysJAK-STAT signaling pathway, Prolactin signaling pathway, Neddylation Related via 3 shared pathways including JAK-STAT signaling pathway, Prolactin signaling pathway. SOCS5 3 shared pathwaysJAK-STAT signaling pathway, Prolactin signaling pathway, Neddylation Related via 3 shared pathways including JAK-STAT signaling pathway, Prolactin signaling pathway. SOCS7 2 shared pathwaysJAK-STAT signaling pathway, Prolactin signaling pathway Related via 2 shared pathways including JAK-STAT signaling pathway, Prolactin signaling pathway. SOCS2 3 shared pathwaysJAK-STAT signaling pathway, Prolactin signaling pathway, Neddylation Related via 3 shared pathways including JAK-STAT signaling pathway, Prolactin signaling pathway. SOCS4 2 shared pathwaysJAK-STAT signaling pathway, Prolactin signaling pathway Related via 2 shared pathways including JAK-STAT signaling pathway, Prolactin signaling pathway.

Related Gene	Shared Diseases	Shared Disease Names	Shared Pathways	Shared Pathway Names	Shared Evidence Sources	Shared Evidence Names
CISH	0	[]	3	["JAK-STAT signaling pathway","Prolactin signaling pathway","Neddylation"]	0	[]
SOCS5	0	[]	3	["JAK-STAT signaling pathway","Prolactin signaling pathway","Neddylation"]	0	[]
SOCS7	0	[]	2	["JAK-STAT signaling pathway","Prolactin signaling pathway"]	0	[]
SOCS2	0	[]	3	["JAK-STAT signaling pathway","Prolactin signaling pathway","Neddylation"]	0	[]
SOCS4	0	[]	2	["JAK-STAT signaling pathway","Prolactin signaling pathway"]	0	[]

Diseases Linked via Similar Genes

Allergic contact dermatitis Linked via 2 of 5 related genesCISH, SOCS2 Diabetes mellitus type 2 Linked via 2 of 5 related genesSOCS5, SOCS2 Central nervous system cancer Linked via 1 of 5 related genesSOCS5 Color vision deficiency Linked via 1 of 5 related genesSOCS5 Glioma Linked via 1 of 5 related genesSOCS5

Disease	Linked Via (Gene Count)	Linked Via (Gene Names)
Allergic contact dermatitis	2	["CISH","SOCS2"]
Diabetes mellitus type 2	2	["SOCS5","SOCS2"]
Central nervous system cancer	1	["SOCS5"]
Color vision deficiency	1	["SOCS5"]
Glioma	1	["SOCS5"]