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Gene Gene information from NCBI Gene database.
Entrez ID 25992
Gene name Sushi, nidogen and EGF like domains 1
Gene symbol SNED1
Synonyms (NCBI Gene)
IRE-BP1SST3Snep
Chromosome 2
Chromosome location 2q37.3
miRNA miRNA information provided by mirtarbase database.
199 Show/Hide all (199)
miRTarBase ID miRNA Experiments Reference
MIRT016924 hsa-miR-335-5p Microarray 18185580
MIRT714433 hsa-miR-4753-5p HITS-CLIP 19536157
MIRT714432 hsa-miR-590-3p HITS-CLIP 19536157
MIRT714431 hsa-miR-135a-5p HITS-CLIP 19536157
MIRT714430 hsa-miR-135b-5p HITS-CLIP 19536157
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
6 Show/Hide all (6)
GO ID Ontology Definition Evidence Reference
GO:0005112 Function Notch binding IBA
GO:0005509 Function Calcium ion binding IEA
GO:0005576 Component Extracellular region IEA
GO:0007160 Process Cell-matrix adhesion IEA
GO:0031012 Component Extracellular matrix IDA 33724335
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
616634 24696 ENSG00000162804
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q8TER0
Protein name Sushi, nidogen and EGF-like domain-containing protein 1 (Insulin-responsive sequence DNA-binding protein 1) (IRE-BP1)
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00008 EGF 391 → 421 EGF-like domain Domain
PF00008 EGF 433 → 463 EGF-like domain Domain
PF00008 EGF 1311 → 1341 EGF-like domain Domain
PF00008 EGF 623 → 653 EGF-like domain Domain
PF00008 EGF 757 → 787 EGF-like domain Domain
PF00008 EGF 315 → 345 EGF-like domain Domain
PF00008 EGF 545 → 575 EGF-like domain Domain
PF00008 EGF 795 → 825 EGF-like domain Domain
PF00008 EGF 272 → 307 EGF-like domain Domain
PF00008 EGF 833 → 863 EGF-like domain Domain
PF00008 EGF 584 → 614 EGF-like domain Domain
PF00041 fn3 1105 → 1186 Fibronectin type III domain Domain
PF00041 fn3 908 → 991 Fibronectin type III domain Domain
PF00041 fn3 1005 → 1088 Fibronectin type III domain Domain
PF06119 NIDO 168 → 257 Nidogen-like Family
PF12661 hEGF 666 → 687 Human growth factor-like EGF Domain
PF12661 hEGF 474 → 494 Human growth factor-like EGF Domain
PF12661 hEGF 358 → 379 Human growth factor-like EGF Domain
Sequence
MRHGVAWALLVAAALGLGARGVRGAVALADFYPFGAERGDAVTPKQDDGGSGLRPLSVPF
PFFGAEHSGLYVNNNGIISFLKEVSQFTPVAFPIAKDRCVVAAFWADVDNRRAGDVYYRE
ATDPAMLRRATEDVRHYFPELLDFNATWVFVATWYRVTFFGGSSSSPVNTFQTVLITDGK
LSFTIFNYESIVWTTGTHASSGGNATGLGGIAAQAGFNAGDGQRYFSIPGSRTADMAEVE
TTTNVGVPGRWAFRIDD
AQVRVGGCGHTTSVCLALRPCLNGGKCIDDCVTGNPSYTCSCL
SGFTGRR
CHLDVNECASQPCQNGGTCTHGINSFRCQCPAGFGGPTCETAQSPCDTKECQH
GGQCQVENGSAVCVCQAGY
TGAACEMDVDDCSPDPCLNGGSCVDLVGNYTCLCAEPFKGL
R
CETGDHPVPDACLSAPCHNGGTCVDADQGYVCECPEGFMGLDCRERVPDDCECRNGGRC
LGANTTLCQCPLGF
FGLLCEFEITAMPCNMNTQCPDGGYCMEHGGSYLCVCHTDHNASHS
LPSPCDSDPCFNGGSCDAHDDSYTCECPRGFHGKHCEKARPHLCSSGPCRNGGTCKEAGG
EYHCSCPYRFTGRH
CEIGKPDSCASGPCHNGGTCFHYIGKYKCDCPPGFSGRHCEIAPSP
CFRSPCVNGGTCEDRDTDFFCHCQAGYMGRRCQAEVDCGPPEEVKHATLRFNGTRLGAVA
LYACDRGYSLSAPSRIRVCQPHGVWSEPPQCLEIDECRSQPCLHGGSCQDRVAGYLCLCS
TGYEGAH
CELERDECRAHPCRNGGSCRNLPGAYVCRCPAGFVGVHCETEVDACDSSPCQH
GGRCESGGGAYLCVCPESFFGYH
CETVSDPCFSSPCGGRGYCLASNGSHSCTCKVGYTGE
DCAKELFPPTALKMERVEESGVSISWNPPNGPAARQMLDGYAVTYVSSDGSYRRTDFVDR
TRSSHQLQALAAGRAYNISVFSVKRNSNNKN
DISRPAVLLARTRPRPVEGFEVTNVTAST
ISVQWALHRIRHATVSGVRVSIRHPEALRDQATDVDRSVDRFTFRALLPGKRYTIQLTTL
SGLRGEEH
PTESLATAPTHVWTRPLPPANLTAARVTATSAHVVWDAPTPGSLLEAYVINV
TTSQSTKSRYVPNGKLASYTVRDLLPGRRYQLSVIAVQSTELGPQH
SEPAHLYIITSPRD
GADRRWHQGGHHPRVLKNRPPPARLPELRLLNDHSAPETPTQPPRFSELVDGRGRVSARF
GGSPSKAATVRSQPTASAQLENMEEAPKRVSLALQLPEHGSKDIGNVPGNCSENPCQNGG
TCVPGADAHSCDCGPGFKGRR
CELACIKVSRPCTRLFSETKAFPVWEGGVCHHVYKRVYR
VHQDICFKESCESTSLKKTPNRKQSKSQTLEKS
Sequence length 1413
Interactions View interactions
Associated diseases Disease associations from ClinVar (causal & non-causal) and other databases (OMIM, Orphanet, GWAS, etc.).
6
Evidence Score: ★☆☆☆☆  Gene-disease association found in Text Mining only ★★☆☆☆  Found in Text Mining and Unknown/Other Associations ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
Show/Hide Unknown Diseases (6)
Phenotype Name Clinical Significance Source Reference Evidence Score
Clear cell carcinoma of kidney Benign ClinVar —
★★★★★
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
Colon adenocarcinoma Benign ClinVar —
★★★★★
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
Malignant tumor of esophagus Benign ClinVar —
★★★★★
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
Sarcoma Benign ClinVar —
★★★★★
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
Thyroid cancer, nonmedullary, 1 Benign ClinVar —
★★★★★
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
Associations from Text Mining Disease associations identified through text mining
Show/Hide Text Mining Associations (32)
Disease Name Disease (Merged) Source PMID Relationship Type Evidence Score
Adenocarcinoma Adenocarcinoma BEFREE 30076481
★★★★★
★☆☆☆☆
Found in Text Mining only
Adenoma Adenoma BEFREE 8620499
★★★★★
★☆☆☆☆
Found in Text Mining only
Adenomatous Polyposis Coli Multiple polyposis syndrome BEFREE 8620499
★★★★★
★☆☆☆☆
Found in Text Mining only
Bipolar Disorder Bipolar Disorder GWASCAT_DG 25944848
★★★★★
★☆☆☆☆
Found in Text Mining only
Carcinoma Carcinoma BEFREE 8620499
★★★★★
★☆☆☆☆
Found in Text Mining only
Cardiovascular Diseases Cardiovascular disease Pubtator 28862951 Associate
★★★★★
★☆☆☆☆
Found in Text Mining only
Colon Carcinoma Colon Carcinoma BEFREE 18587421
★★★★★
★☆☆☆☆
Found in Text Mining only
Colorectal Neoplasms Colorectal neoplasm Pubtator 18587421 Associate
★★★★★
★☆☆☆☆
Found in Text Mining only
Diabetes Diabetes BEFREE 18566119
★★★★★
★☆☆☆☆
Found in Text Mining only
Diabetes Mellitus Diabetes Mellitus BEFREE 18566119
★★★★★
★☆☆☆☆
Found in Text Mining only