SMG5 (SMG5 nonsense mediated mRNA decay factor)

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Gene

• Entrez ID: 23381
• Gene name: SMG5 nonsense mediated mRNA decay factor
• Gene symbol: SMG5
• Synonyms (NCBI Gene): EST1B, LPTS-RP1, LPTSRP1, SMG-5
• Chromosome: 1
• Chromosome location: 1q22
• Summary: SMG5 is involved in nonsense-mediated mRNA decay (Ohnishi et al., 2003 [PubMed 14636577]).[supplied by OMIM, Mar 2008]

miRNA Show/Hide all (394)

miRTarBase ID	miRNA	Experiments	Reference
MIRT043281	hsa-miR-331-3p	CLASH	23622248
MIRT041477	hsa-miR-193b-3p	CLASH	23622248
MIRT038568	hsa-miR-106b-3p	CLASH	23622248
MIRT038311	hsa-miR-130b-5p	CLASH	23622248
MIRT037745	hsa-miR-708-5p	CLASH	23622248
MIRT1373392	hsa-miR-1184	CLIP-seq
MIRT1373393	hsa-miR-1205	CLIP-seq
MIRT1373394	hsa-miR-1224-5p	CLIP-seq
MIRT1373395	hsa-miR-1236	CLIP-seq
MIRT1373396	hsa-miR-1254	CLIP-seq
MIRT1373397	hsa-miR-1262	CLIP-seq
MIRT1373398	hsa-miR-1289	CLIP-seq
MIRT1373399	hsa-miR-1293	CLIP-seq
MIRT1373400	hsa-miR-1321	CLIP-seq
MIRT1373401	hsa-miR-1324	CLIP-seq
MIRT1373402	hsa-miR-138	CLIP-seq
MIRT1373403	hsa-miR-1827	CLIP-seq
MIRT1373404	hsa-miR-1909	CLIP-seq
MIRT1373405	hsa-miR-1912	CLIP-seq
MIRT1373406	hsa-miR-22	CLIP-seq
MIRT1373407	hsa-miR-2392	CLIP-seq
MIRT1373408	hsa-miR-2467-3p	CLIP-seq
MIRT1373409	hsa-miR-28-5p	CLIP-seq
MIRT1373410	hsa-miR-2861	CLIP-seq
MIRT1373411	hsa-miR-3064-5p	CLIP-seq
MIRT1373412	hsa-miR-3116	CLIP-seq
MIRT1373413	hsa-miR-3123	CLIP-seq
MIRT1373414	hsa-miR-3130-5p	CLIP-seq
MIRT1373415	hsa-miR-3139	CLIP-seq
MIRT1373416	hsa-miR-3150b-3p	CLIP-seq
MIRT1373417	hsa-miR-3158-5p	CLIP-seq
MIRT1373418	hsa-miR-3160-3p	CLIP-seq
MIRT1373419	hsa-miR-3173-3p	CLIP-seq
MIRT1373420	hsa-miR-3179	CLIP-seq
MIRT1373421	hsa-miR-3198	CLIP-seq
MIRT1373422	hsa-miR-3202	CLIP-seq
MIRT1373423	hsa-miR-342-5p	CLIP-seq
MIRT1373424	hsa-miR-34b	CLIP-seq
MIRT1373425	hsa-miR-3605-5p	CLIP-seq
MIRT1373426	hsa-miR-361-3p	CLIP-seq
MIRT1373427	hsa-miR-362-5p	CLIP-seq
MIRT1373428	hsa-miR-3667-3p	CLIP-seq
MIRT1373429	hsa-miR-3678-3p	CLIP-seq
MIRT1373430	hsa-miR-3679-3p	CLIP-seq
MIRT1373431	hsa-miR-3915	CLIP-seq
MIRT1373432	hsa-miR-3918	CLIP-seq
MIRT1373433	hsa-miR-3919	CLIP-seq
MIRT1373434	hsa-miR-4267	CLIP-seq
MIRT1373435	hsa-miR-4270	CLIP-seq
MIRT1373436	hsa-miR-4281	CLIP-seq
MIRT1373437	hsa-miR-4286	CLIP-seq
MIRT1373438	hsa-miR-4287	CLIP-seq
MIRT1373439	hsa-miR-4294	CLIP-seq
MIRT1373440	hsa-miR-4309	CLIP-seq
MIRT1373441	hsa-miR-4323	CLIP-seq
MIRT1373442	hsa-miR-4326	CLIP-seq
MIRT1373443	hsa-miR-4418	CLIP-seq
MIRT1373444	hsa-miR-4441	CLIP-seq
MIRT1373445	hsa-miR-4476	CLIP-seq
MIRT1373446	hsa-miR-4482	CLIP-seq
MIRT1373447	hsa-miR-4483	CLIP-seq
MIRT1373448	hsa-miR-4512	CLIP-seq
MIRT1373449	hsa-miR-4520a-5p	CLIP-seq
MIRT1373450	hsa-miR-4520b-5p	CLIP-seq
MIRT1373451	hsa-miR-4649-3p	CLIP-seq
MIRT1373452	hsa-miR-4651	CLIP-seq
MIRT1373453	hsa-miR-4656	CLIP-seq
MIRT1373454	hsa-miR-4664-5p	CLIP-seq
MIRT1373455	hsa-miR-4678	CLIP-seq
MIRT1373456	hsa-miR-4685-3p	CLIP-seq
MIRT1373457	hsa-miR-4689	CLIP-seq
MIRT1373458	hsa-miR-4690-3p	CLIP-seq
MIRT1373459	hsa-miR-4701-3p	CLIP-seq
MIRT1373460	hsa-miR-4733-3p	CLIP-seq
MIRT1373461	hsa-miR-4739	CLIP-seq
MIRT1373462	hsa-miR-4755-3p	CLIP-seq
MIRT1373463	hsa-miR-4756-3p	CLIP-seq
MIRT1373464	hsa-miR-4756-5p	CLIP-seq
MIRT1373465	hsa-miR-4758-3p	CLIP-seq
MIRT1373466	hsa-miR-4766-5p	CLIP-seq
MIRT1373467	hsa-miR-4784	CLIP-seq
MIRT1373468	hsa-miR-488	CLIP-seq
MIRT1373469	hsa-miR-500b	CLIP-seq
MIRT1373470	hsa-miR-509-3-5p	CLIP-seq
MIRT1373471	hsa-miR-509-5p	CLIP-seq
MIRT1373472	hsa-miR-517b	CLIP-seq
MIRT1373473	hsa-miR-520a-5p	CLIP-seq
MIRT1373474	hsa-miR-525-5p	CLIP-seq
MIRT1373475	hsa-miR-541	CLIP-seq
MIRT1373476	hsa-miR-552	CLIP-seq
MIRT1373477	hsa-miR-556-3p	CLIP-seq
MIRT1373478	hsa-miR-558	CLIP-seq
MIRT1373479	hsa-miR-604	CLIP-seq
MIRT1373480	hsa-miR-608	CLIP-seq
MIRT1373481	hsa-miR-627	CLIP-seq
MIRT1373482	hsa-miR-647	CLIP-seq
MIRT1373483	hsa-miR-654-5p	CLIP-seq
MIRT1373484	hsa-miR-661	CLIP-seq
MIRT1373485	hsa-miR-708	CLIP-seq
MIRT1373486	hsa-miR-764	CLIP-seq
MIRT1373487	hsa-miR-765	CLIP-seq
MIRT1373488	hsa-miR-924	CLIP-seq
MIRT1373392	hsa-miR-1184	CLIP-seq
MIRT1373393	hsa-miR-1205	CLIP-seq
MIRT1373394	hsa-miR-1224-5p	CLIP-seq
MIRT2111150	hsa-miR-1245b-5p	CLIP-seq
MIRT1373396	hsa-miR-1254	CLIP-seq
MIRT1373397	hsa-miR-1262	CLIP-seq
MIRT2111151	hsa-miR-1303	CLIP-seq
MIRT2111152	hsa-miR-1470	CLIP-seq
MIRT1373403	hsa-miR-1827	CLIP-seq
MIRT2111153	hsa-miR-185	CLIP-seq
MIRT2111154	hsa-miR-188-3p	CLIP-seq
MIRT2111155	hsa-miR-1914	CLIP-seq
MIRT1373406	hsa-miR-22	CLIP-seq
MIRT1373407	hsa-miR-2392	CLIP-seq
MIRT1373410	hsa-miR-2861	CLIP-seq
MIRT2111156	hsa-miR-296-5p	CLIP-seq
MIRT1373411	hsa-miR-3064-5p	CLIP-seq
MIRT1373412	hsa-miR-3116	CLIP-seq
MIRT2111157	hsa-miR-3124-3p	CLIP-seq
MIRT2111158	hsa-miR-3125	CLIP-seq
MIRT2111159	hsa-miR-3136-5p	CLIP-seq
MIRT2111160	hsa-miR-3142	CLIP-seq
MIRT1373416	hsa-miR-3150b-3p	CLIP-seq
MIRT2111161	hsa-miR-3151	CLIP-seq
MIRT2111162	hsa-miR-3167	CLIP-seq
MIRT1373419	hsa-miR-3173-3p	CLIP-seq
MIRT1373422	hsa-miR-3202	CLIP-seq
MIRT2111163	hsa-miR-330-3p	CLIP-seq
MIRT1373423	hsa-miR-342-5p	CLIP-seq
MIRT2111164	hsa-miR-345	CLIP-seq
MIRT1373425	hsa-miR-3605-5p	CLIP-seq
MIRT1373427	hsa-miR-362-5p	CLIP-seq
MIRT1373431	hsa-miR-3915	CLIP-seq
MIRT2111165	hsa-miR-3916	CLIP-seq
MIRT2111166	hsa-miR-3921	CLIP-seq
MIRT1373436	hsa-miR-4281	CLIP-seq
MIRT2111167	hsa-miR-4290	CLIP-seq
MIRT2111168	hsa-miR-4293	CLIP-seq
MIRT2111169	hsa-miR-4303	CLIP-seq
MIRT2111170	hsa-miR-4306	CLIP-seq
MIRT2111171	hsa-miR-4439	CLIP-seq
MIRT2111172	hsa-miR-4447	CLIP-seq
MIRT2111173	hsa-miR-4468	CLIP-seq
MIRT2111174	hsa-miR-4469	CLIP-seq
MIRT2111175	hsa-miR-4472	CLIP-seq
MIRT1373448	hsa-miR-4512	CLIP-seq
MIRT2111176	hsa-miR-4513	CLIP-seq
MIRT2111177	hsa-miR-4644	CLIP-seq
MIRT1373452	hsa-miR-4651	CLIP-seq
MIRT2111178	hsa-miR-4653-5p	CLIP-seq
MIRT1373453	hsa-miR-4656	CLIP-seq
MIRT1373454	hsa-miR-4664-5p	CLIP-seq
MIRT2111179	hsa-miR-4667-3p	CLIP-seq
MIRT1373457	hsa-miR-4689	CLIP-seq
MIRT1373458	hsa-miR-4690-3p	CLIP-seq
MIRT1373459	hsa-miR-4701-3p	CLIP-seq
MIRT2111180	hsa-miR-4747-5p	CLIP-seq
MIRT2111181	hsa-miR-4757-5p	CLIP-seq
MIRT1373466	hsa-miR-4766-5p	CLIP-seq
MIRT2111182	hsa-miR-4779	CLIP-seq
MIRT1373467	hsa-miR-4784	CLIP-seq
MIRT2111183	hsa-miR-486-3p	CLIP-seq
MIRT1373468	hsa-miR-488	CLIP-seq
MIRT2111184	hsa-miR-499a-5p	CLIP-seq
MIRT1373469	hsa-miR-500b	CLIP-seq
MIRT1373473	hsa-miR-520a-5p	CLIP-seq
MIRT1373474	hsa-miR-525-5p	CLIP-seq
MIRT2111185	hsa-miR-532-3p	CLIP-seq
MIRT1373478	hsa-miR-558	CLIP-seq
MIRT1373479	hsa-miR-604	CLIP-seq
MIRT1373480	hsa-miR-608	CLIP-seq
MIRT2111186	hsa-miR-646	CLIP-seq
MIRT1373482	hsa-miR-647	CLIP-seq
MIRT1373484	hsa-miR-661	CLIP-seq
MIRT2111187	hsa-miR-671-5p	CLIP-seq
MIRT2111188	hsa-miR-876-5p	CLIP-seq
MIRT2111189	hsa-miR-877	CLIP-seq
MIRT2111190	hsa-miR-940	CLIP-seq
MIRT2334316	hsa-miR-103a	CLIP-seq
MIRT2334317	hsa-miR-107	CLIP-seq
MIRT1373392	hsa-miR-1184	CLIP-seq
MIRT1373393	hsa-miR-1205	CLIP-seq
MIRT1373397	hsa-miR-1262	CLIP-seq
MIRT1373398	hsa-miR-1289	CLIP-seq
MIRT1373401	hsa-miR-1324	CLIP-seq
MIRT1373402	hsa-miR-138	CLIP-seq
MIRT2334318	hsa-miR-1539	CLIP-seq
MIRT1373403	hsa-miR-1827	CLIP-seq
MIRT2111153	hsa-miR-185	CLIP-seq
MIRT2111154	hsa-miR-188-3p	CLIP-seq
MIRT1373404	hsa-miR-1909	CLIP-seq
MIRT2334319	hsa-miR-1910	CLIP-seq
MIRT2334320	hsa-miR-214	CLIP-seq
MIRT1373410	hsa-miR-2861	CLIP-seq
MIRT1373411	hsa-miR-3064-5p	CLIP-seq
MIRT2334321	hsa-miR-3065-3p	CLIP-seq
MIRT1373413	hsa-miR-3123	CLIP-seq
MIRT2334322	hsa-miR-3127-3p	CLIP-seq
MIRT2111161	hsa-miR-3151	CLIP-seq
MIRT2334323	hsa-miR-3154	CLIP-seq
MIRT1373418	hsa-miR-3160-3p	CLIP-seq
MIRT2334324	hsa-miR-3185	CLIP-seq
MIRT2334325	hsa-miR-3193	CLIP-seq
MIRT2334326	hsa-miR-3194-5p	CLIP-seq
MIRT1373421	hsa-miR-3198	CLIP-seq
MIRT1373422	hsa-miR-3202	CLIP-seq
MIRT2111163	hsa-miR-330-3p	CLIP-seq
MIRT2334327	hsa-miR-335	CLIP-seq
MIRT1373424	hsa-miR-34b	CLIP-seq
MIRT2334328	hsa-miR-3619-5p	CLIP-seq
MIRT1373428	hsa-miR-3667-3p	CLIP-seq
MIRT1373431	hsa-miR-3915	CLIP-seq
MIRT1373432	hsa-miR-3918	CLIP-seq
MIRT2334329	hsa-miR-3928	CLIP-seq
MIRT2334330	hsa-miR-3944-5p	CLIP-seq
MIRT2334331	hsa-miR-4283	CLIP-seq
MIRT1373437	hsa-miR-4286	CLIP-seq
MIRT1373439	hsa-miR-4294	CLIP-seq
MIRT2334332	hsa-miR-4300	CLIP-seq
MIRT2111170	hsa-miR-4306	CLIP-seq
MIRT1373440	hsa-miR-4309	CLIP-seq
MIRT1373441	hsa-miR-4323	CLIP-seq
MIRT1373442	hsa-miR-4326	CLIP-seq
MIRT1373443	hsa-miR-4418	CLIP-seq
MIRT2334333	hsa-miR-4435	CLIP-seq
MIRT2111172	hsa-miR-4447	CLIP-seq
MIRT2334334	hsa-miR-4456	CLIP-seq
MIRT2334335	hsa-miR-4459	CLIP-seq
MIRT2111175	hsa-miR-4472	CLIP-seq
MIRT1373445	hsa-miR-4476	CLIP-seq
MIRT2334336	hsa-miR-4489	CLIP-seq
MIRT2334337	hsa-miR-4492	CLIP-seq
MIRT2334338	hsa-miR-4498	CLIP-seq
MIRT1373448	hsa-miR-4512	CLIP-seq
MIRT2334339	hsa-miR-455-3p	CLIP-seq
MIRT2111177	hsa-miR-4644	CLIP-seq
MIRT1373451	hsa-miR-4649-3p	CLIP-seq
MIRT1373452	hsa-miR-4651	CLIP-seq
MIRT1373455	hsa-miR-4678	CLIP-seq
MIRT1373458	hsa-miR-4690-3p	CLIP-seq
MIRT1373459	hsa-miR-4701-3p	CLIP-seq
MIRT2334340	hsa-miR-4710	CLIP-seq
MIRT2334341	hsa-miR-4722-5p	CLIP-seq
MIRT1373460	hsa-miR-4733-3p	CLIP-seq
MIRT2111180	hsa-miR-4747-5p	CLIP-seq
MIRT2111181	hsa-miR-4757-5p	CLIP-seq
MIRT1373465	hsa-miR-4758-3p	CLIP-seq
MIRT2334342	hsa-miR-4764-5p	CLIP-seq
MIRT2334343	hsa-miR-4768-3p	CLIP-seq
MIRT2334344	hsa-miR-4778-5p	CLIP-seq
MIRT2111182	hsa-miR-4779	CLIP-seq
MIRT2334345	hsa-miR-491-5p	CLIP-seq
MIRT1373470	hsa-miR-509-3-5p	CLIP-seq
MIRT1373471	hsa-miR-509-5p	CLIP-seq
MIRT2334346	hsa-miR-516b	CLIP-seq
MIRT2111185	hsa-miR-532-3p	CLIP-seq
MIRT1373475	hsa-miR-541	CLIP-seq
MIRT1373479	hsa-miR-604	CLIP-seq
MIRT1373480	hsa-miR-608	CLIP-seq
MIRT2334347	hsa-miR-637	CLIP-seq
MIRT1373482	hsa-miR-647	CLIP-seq
MIRT1373483	hsa-miR-654-5p	CLIP-seq
MIRT1373484	hsa-miR-661	CLIP-seq
MIRT2334348	hsa-miR-761	CLIP-seq
MIRT2334349	hsa-miR-762	CLIP-seq
MIRT1373487	hsa-miR-765	CLIP-seq
MIRT2334350	hsa-miR-920	CLIP-seq
MIRT2334351	hsa-miR-939	CLIP-seq
MIRT2111190	hsa-miR-940	CLIP-seq
MIRT1373392	hsa-miR-1184	CLIP-seq
MIRT2111154	hsa-miR-188-3p	CLIP-seq
MIRT1373411	hsa-miR-3064-5p	CLIP-seq
MIRT2111157	hsa-miR-3124-3p	CLIP-seq
MIRT2394877	hsa-miR-4453	CLIP-seq
MIRT2394878	hsa-miR-4538	CLIP-seq
MIRT1373458	hsa-miR-4690-3p	CLIP-seq
MIRT2111180	hsa-miR-4747-5p	CLIP-seq
MIRT2111185	hsa-miR-532-3p	CLIP-seq
MIRT1373479	hsa-miR-604	CLIP-seq
MIRT1373482	hsa-miR-647	CLIP-seq
MIRT2334316	hsa-miR-103a	CLIP-seq
MIRT2334317	hsa-miR-107	CLIP-seq
MIRT1373392	hsa-miR-1184	CLIP-seq
MIRT2334320	hsa-miR-214	CLIP-seq
MIRT2334328	hsa-miR-3619-5p	CLIP-seq
MIRT2334335	hsa-miR-4459	CLIP-seq
MIRT2334341	hsa-miR-4722-5p	CLIP-seq
MIRT2334348	hsa-miR-761	CLIP-seq
MIRT1373487	hsa-miR-765	CLIP-seq
MIRT2334316	hsa-miR-103a	CLIP-seq
MIRT2334317	hsa-miR-107	CLIP-seq
MIRT1373392	hsa-miR-1184	CLIP-seq
MIRT2334320	hsa-miR-214	CLIP-seq
MIRT2334328	hsa-miR-3619-5p	CLIP-seq
MIRT2334335	hsa-miR-4459	CLIP-seq
MIRT2334341	hsa-miR-4722-5p	CLIP-seq
MIRT2334348	hsa-miR-761	CLIP-seq
MIRT1373487	hsa-miR-765	CLIP-seq
MIRT1373392	hsa-miR-1184	CLIP-seq
MIRT2628323	hsa-miR-1225-3p	CLIP-seq
MIRT2111150	hsa-miR-1245b-5p	CLIP-seq
MIRT2628324	hsa-miR-1250	CLIP-seq
MIRT2628325	hsa-miR-146b-3p	CLIP-seq
MIRT1373403	hsa-miR-1827	CLIP-seq
MIRT2111154	hsa-miR-188-3p	CLIP-seq
MIRT2111155	hsa-miR-1914	CLIP-seq
MIRT2628326	hsa-miR-1972	CLIP-seq
MIRT1373409	hsa-miR-28-5p	CLIP-seq
MIRT1373410	hsa-miR-2861	CLIP-seq
MIRT1373411	hsa-miR-3064-5p	CLIP-seq
MIRT1373415	hsa-miR-3139	CLIP-seq
MIRT2111160	hsa-miR-3142	CLIP-seq
MIRT2111161	hsa-miR-3151	CLIP-seq
MIRT1373418	hsa-miR-3160-3p	CLIP-seq
MIRT2628327	hsa-miR-3173-5p	CLIP-seq
MIRT2628328	hsa-miR-3184	CLIP-seq
MIRT2628329	hsa-miR-3977	CLIP-seq
MIRT2628330	hsa-miR-423-5p	CLIP-seq
MIRT2111168	hsa-miR-4293	CLIP-seq
MIRT2628331	hsa-miR-4308	CLIP-seq
MIRT2628332	hsa-miR-4494	CLIP-seq
MIRT2628333	hsa-miR-4645-5p	CLIP-seq
MIRT1373451	hsa-miR-4649-3p	CLIP-seq
MIRT2628334	hsa-miR-4650-5p	CLIP-seq
MIRT2628335	hsa-miR-4673	CLIP-seq
MIRT2628336	hsa-miR-4684-5p	CLIP-seq
MIRT2628337	hsa-miR-4716-3p	CLIP-seq
MIRT2628338	hsa-miR-4717-5p	CLIP-seq
MIRT2628339	hsa-miR-4723-5p	CLIP-seq
MIRT2628340	hsa-miR-4725-5p	CLIP-seq
MIRT2628341	hsa-miR-4763-5p	CLIP-seq
MIRT2628342	hsa-miR-4786-5p	CLIP-seq
MIRT2628343	hsa-miR-504	CLIP-seq
MIRT2628344	hsa-miR-508-5p	CLIP-seq
MIRT2111185	hsa-miR-532-3p	CLIP-seq
MIRT2628345	hsa-miR-544b	CLIP-seq
MIRT2628346	hsa-miR-596	CLIP-seq
MIRT1373479	hsa-miR-604	CLIP-seq
MIRT2628347	hsa-miR-615-3p	CLIP-seq
MIRT1373482	hsa-miR-647	CLIP-seq
MIRT1373485	hsa-miR-708	CLIP-seq
MIRT1373487	hsa-miR-765	CLIP-seq
MIRT2628348	hsa-miR-769-5p	CLIP-seq
MIRT2628349	hsa-miR-874	CLIP-seq
MIRT2628350	hsa-miR-942	CLIP-seq
MIRT1373392	hsa-miR-1184	CLIP-seq
MIRT2628323	hsa-miR-1225-3p	CLIP-seq
MIRT2111150	hsa-miR-1245b-5p	CLIP-seq
MIRT2628324	hsa-miR-1250	CLIP-seq
MIRT2628325	hsa-miR-146b-3p	CLIP-seq
MIRT1373403	hsa-miR-1827	CLIP-seq
MIRT2111154	hsa-miR-188-3p	CLIP-seq
MIRT2111155	hsa-miR-1914	CLIP-seq
MIRT2628326	hsa-miR-1972	CLIP-seq
MIRT1373409	hsa-miR-28-5p	CLIP-seq
MIRT1373410	hsa-miR-2861	CLIP-seq
MIRT1373411	hsa-miR-3064-5p	CLIP-seq
MIRT1373415	hsa-miR-3139	CLIP-seq
MIRT2111160	hsa-miR-3142	CLIP-seq
MIRT2111161	hsa-miR-3151	CLIP-seq
MIRT1373418	hsa-miR-3160-3p	CLIP-seq
MIRT2628327	hsa-miR-3173-5p	CLIP-seq
MIRT2628328	hsa-miR-3184	CLIP-seq
MIRT2628329	hsa-miR-3977	CLIP-seq
MIRT2628330	hsa-miR-423-5p	CLIP-seq
MIRT2111168	hsa-miR-4293	CLIP-seq
MIRT2628331	hsa-miR-4308	CLIP-seq
MIRT2628332	hsa-miR-4494	CLIP-seq
MIRT2628333	hsa-miR-4645-5p	CLIP-seq
MIRT1373451	hsa-miR-4649-3p	CLIP-seq
MIRT2628334	hsa-miR-4650-5p	CLIP-seq
MIRT2628335	hsa-miR-4673	CLIP-seq
MIRT2628337	hsa-miR-4716-3p	CLIP-seq
MIRT2628338	hsa-miR-4717-5p	CLIP-seq
MIRT2628339	hsa-miR-4723-5p	CLIP-seq
MIRT2628340	hsa-miR-4725-5p	CLIP-seq
MIRT2628341	hsa-miR-4763-5p	CLIP-seq
MIRT2628342	hsa-miR-4786-5p	CLIP-seq
MIRT2628343	hsa-miR-504	CLIP-seq
MIRT2628344	hsa-miR-508-5p	CLIP-seq
MIRT2111185	hsa-miR-532-3p	CLIP-seq
MIRT2628345	hsa-miR-544b	CLIP-seq
MIRT2628346	hsa-miR-596	CLIP-seq
MIRT1373479	hsa-miR-604	CLIP-seq
MIRT2628347	hsa-miR-615-3p	CLIP-seq
MIRT1373482	hsa-miR-647	CLIP-seq
MIRT2111187	hsa-miR-671-5p	CLIP-seq
MIRT1373485	hsa-miR-708	CLIP-seq
MIRT1373487	hsa-miR-765	CLIP-seq
MIRT2628348	hsa-miR-769-5p	CLIP-seq
MIRT2628349	hsa-miR-874	CLIP-seq
MIRT2628350	hsa-miR-942	CLIP-seq

Gene ontology (GO) Show/Hide all (22)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000184	Process	Nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	IBA
GO:0000184	Process	Nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	IEA
GO:0000184	Process	Nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	TAS	16488880
GO:0005515	Function	Protein binding	IPI	12699629, 14636577, 20930030, 21145460, 23348841
GO:0005634	Component	Nucleus	IDA	14636577
GO:0005634	Component	Nucleus	IEA
GO:0005697	Component	Telomerase holoenzyme complex	IBA
GO:0005737	Component	Cytoplasm	IDA	14636577
GO:0005737	Component	Cytoplasm	IEA
GO:0005829	Component	Cytosol	TAS
GO:0006406	Process	MRNA export from nucleus	TAS	16488880
GO:0031625	Function	Ubiquitin protein ligase binding	IPI	16809764
GO:0032204	Process	Regulation of telomere maintenance	IMP	16809764
GO:0032210	Process	Regulation of telomere maintenance via telomerase	TAS	16507993
GO:0035303	Process	Regulation of dephosphorylation	IMP	14636577
GO:0036464	Component	Cytoplasmic ribonucleoprotein granule	IDA
GO:0042162	Function	Telomeric DNA binding	IBA
GO:0042162	Function	Telomeric DNA binding	IDA	17916692
GO:0042826	Function	Histone deacetylase binding	IPI	16809764
GO:0051721	Function	Protein phosphatase 2A binding	IDA	14636577
GO:0070034	Function	Telomerase RNA binding	IBA
GO:0070034	Function	Telomerase RNA binding	IPI	15857955

Other IDs

• MIM: 610962
• HGNC: 24644
• e!Ensembl: ENSG00000198952

Protein

• UniProt ID: Q9UPR3
• Protein name: Nonsense-mediated mRNA decay factor SMG5 (EST1-like protein B) (LPTS-RP1) (LPTS-interacting protein) (SMG-5 homolog) (hSMG-5)
• Protein function: Plays a role in nonsense-mediated mRNA decay. Does not have RNase activity by itself. Promotes dephosphorylation of UPF1. Together with SMG7 is thought to provide a link to the mRNA degradation machinery involving exonucleolytic pathways, and to
• PDB: 2HWY
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF10373	EST1_DNA_bind	197 → 427	Est1 DNA/RNA binding domain	Family
  PF10373	EST1_DNA_bind	627 → 744	Est1 DNA/RNA binding domain	Family
  PF10374	EST1	77 → 189	Telomerase activating protein Est1	Family
  PF13638	PIN_4	857 → 965	PIN domain	Domain

• Tissue specificity: TISSUE SPECIFICITY: Ubiquitous. {ECO:0000269|PubMed:12699629, ECO:0000269|PubMed:14636577}.
• Sequence:

  MSQGPPTGESSEPEAKVLHTKRLYRAVVEAVHRLDLILCNKTAYQEVFKPENISLRNKLR
  ELCVKLMFLHPVDYGRKAEELLWRKVYYEVIQLIKTNKKHIHSRSTLECAYRTHLVAGIG
  FYQHLLLYIQSHYQLELQCCIDWTHVTDPLIGCKKPVSASGKEMDWAQMACHRCLVYLGD
  LSRYQNELAGVDTELLAERFYYQALSVAPQIGMPFNQLGTLAGSKYYNVEAMYCYLRCIQ
  SEVSFEGAYGNLKRLYDKAAKMYHQLKKCETRKLSPGKKRCKDIKRLLVNFMYLQSLLQP
  KSSSVDSELTSLCQSVLEDFNLCLFYLPSSPNLSLASEDEEEYESGYAFLPDLLIFQMVI
  ICLMCVHSLERAGSKQYSAAIAFTLALFSHLVNHVNIRLQAELEEGENPVPAFQSDGTDE
  PESKEPVEKEEEPDPEPPPVTPQVGEGRKSRKFSRLSCLRRRRHPPKVGDDSDLSEGFES
  DSSHDSARASEGSDSGSDKSLEGGGTAFDAETDSEMNSQESRSDLEDMEEEEGTRSPTLE
  PPRGRSEAPDSLNGPLGPSEASIASNLQAMSTQMFQTKRCFRLAPTFSNLLLQPTTNPHT
  SASHRPCVNGDVDKPSEPASEEGSESEGSESSGRSCRNERSIQEKLQVLMAEGLLPAVKV
  FLDWLRTNPDLIIVCAQSSQSLWNRLSVLLNLLPAAGELQESGLALCPEVQDLLEGCELP
  DLPSSLLLPEDMALRNLPPLRAAHRRFNFDTDRPLLSTLEESVVRICCIRSFGHFIARLQ
  GSILQFNPEVGIFVSIAQSEQESLLQQAQAQFRMAQEEARRNRLMRDMAQLRLQLEVSQL
  EGSLQQPKAQSAMSPYLVPDTQALCHHLPVIRQLATSGRFIVIIPRTVIDGLDLLKKEHP
  GARDGIRYLEAEFKKGNRYIRCQKEVGKSFERHKLKRQDADAWTLYKILDSCKQLTLAQG
  AGEEDPSGMVTIITGLPLDNPSVLSGPMQAALQAAAHASVDIKNVLDFYKQWKEIG

• Sequence length: 1016

Pathways

KEGG Pathway:

mRNA surveillance pathway

Reactome Pathway:

Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)

Associated diseases

Evidence Score:

• ★☆☆☆☆  Gene-disease association found in Text Mining only
• ★★☆☆☆  Found in Text Mining and Unknown/Other Associations
• ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources
• ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
• ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Unknown / Other Associations
Phenotype Name	Clinical Significance	Source	Reference	Evidence Score
Familial cancer of breast	Uncertain significance	ClinVar	—	★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Associations from Text Mining
Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Carcinoma Hepatocellular	Hepatocellular carcinoma	Pubtator	33228611, 33297932, 33411682, 34603786, 37936239, 39529015	Associate	★☆☆☆☆ Found in Text Mining only
Glioma	Glioma	Pubtator	37699361	Associate	★☆☆☆☆ Found in Text Mining only
Prostatic Neoplasms	Prostatic neoplasm	Pubtator	21571633, 37936239	Associate	★☆☆☆☆ Found in Text Mining only

Related Genes

Sort by: Blended Diseases Pathways Evidence source

SMG1 2 shared pathwaysmRNA surveillance pathway, Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) Related via 2 shared pathways including mRNA surveillance pathway, Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC). SMG6 2 shared pathwaysmRNA surveillance pathway, Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) Related via 2 shared pathways including mRNA surveillance pathway, Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC). SMG7 2 shared pathwaysmRNA surveillance pathway, Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) Related via 2 shared pathways including mRNA surveillance pathway, Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC). UPF2 2 shared pathwaysmRNA surveillance pathway, Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) Related via 2 shared pathways including mRNA surveillance pathway, Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC). UPF3A 2 shared pathwaysmRNA surveillance pathway, Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) Related via 2 shared pathways including mRNA surveillance pathway, Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).

Related Gene	Shared Diseases	Shared Disease Names	Shared Pathways	Shared Pathway Names	Shared Evidence Sources	Shared Evidence Names
SMG1	0	[]	2	["mRNA surveillance pathway","Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"]	0	[]
SMG6	0	[]	2	["mRNA surveillance pathway","Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"]	0	[]
SMG7	0	[]	2	["mRNA surveillance pathway","Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"]	0	[]
UPF2	0	[]	2	["mRNA surveillance pathway","Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"]	0	[]
UPF3A	0	[]	2	["mRNA surveillance pathway","Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"]	0	[]

Diseases Linked via Similar Genes

Diverticular disease Linked via 2 of 5 related genesSMG6, UPF2 Androgenetic alopecia Linked via 1 of 5 related genesSMG6 Atrial fibrillation Linked via 1 of 5 related genesSMG6 Attention deficit hyperactivity disorder Linked via 1 of 5 related genesSMG6 Bone fracture Linked via 1 of 5 related genesSMG6

Disease	Linked Via (Gene Count)	Linked Via (Gene Names)
Diverticular disease	2	["SMG6","UPF2"]
Androgenetic alopecia	1	["SMG6"]
Atrial fibrillation	1	["SMG6"]
Attention deficit hyperactivity disorder	1	["SMG6"]
Bone fracture	1	["SMG6"]