SLFN13 (schlafen family member 13)
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Gene
Gene information from NCBI Gene database.
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| Entrez ID | 146857 |
| Gene name | Schlafen family member 13 |
| Gene symbol | SLFN13 |
| Synonyms (NCBI Gene) |
SLFN10hSLFN13
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| Chromosome | 17 |
| Chromosome location | 17q12 |
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miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
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Other IDs
Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
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Protein
Protein information from UniProt database.
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UniProt ID
Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
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Q68D06 | |||||||||||||||
| Protein name | Schlafen family member 13 (EC 3.1.-.-) (Schlafen-13) (hSLFN13) | |||||||||||||||
| Protein function | Endoribonuclease that cleaves tRNAs and rRNAs (PubMed:29563550). Cleaves tRNAs 11 nucleotides from the 3'-terminus at the acceptor stem (PubMed:29563550). Does not act on tRNA(Sec) (PubMed:29563550). Able to restrict HIV-1 virus replication; abi | |||||||||||||||
| Family and domains |
Pfam
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| Sequence |
MEANHCSLGVYPSYPDLVIDVGEVTLGEENRKKLQKTQRDQERARVIRAACALLNSGGGV |
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| Sequence length | 897 | |||||||||||||||
| Interactions | View interactions | |||||||||||||||
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Related Genes
Genes most often co-reported with SLFN13 across shared curated disease and pathway associations.
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Diseases Linked via Similar Genes
Diseases curated for genes most similar to SLFN13 (see Related Genes above), that are NOT already directly curated for SLFN13 itself -- a lead worth checking, not a confirmed association.
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