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Gene Gene information from NCBI Gene database.
Entrez ID 219855
Gene name Solute carrier family 37 member 2
Gene symbol SLC37A2
Synonyms (NCBI Gene)
SPX2pp11662
Chromosome 11
Chromosome location 11q24.2
miRNA miRNA information provided by mirtarbase database.
335 Show/Hide all (335)
miRTarBase ID miRNA Experiments Reference
MIRT018534 hsa-miR-335-5p Microarray 21618216
MIRT490219 hsa-miR-4695-5p PAR-CLIP 20371350
MIRT490218 hsa-miR-1910-3p PAR-CLIP 20371350
MIRT490217 hsa-miR-6511a-5p PAR-CLIP 20371350
MIRT490215 hsa-miR-6847-5p PAR-CLIP 20371350
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
21 Show/Hide all (21)
GO ID Ontology Definition Evidence Reference
GO:0005783 Component Endoplasmic reticulum IEA
GO:0005789 Component Endoplasmic reticulum membrane IBA
GO:0005789 Component Endoplasmic reticulum membrane IDA 21949678
GO:0005789 Component Endoplasmic reticulum membrane IEA
GO:0005789 Component Endoplasmic reticulum membrane TAS
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
619136 20644 ENSG00000134955
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q8TED4
Protein name Glucose-6-phosphate exchanger SLC37A2 (Solute carrier family 37 member 2)
Protein function Inorganic phosphate and glucose-6-phosphate antiporter. May transport cytoplasmic glucose-6-phosphate into the lumen of the endoplasmic reticulum and translocate inorganic phosphate into the opposite direction. Independent of a lumenal glucose-6
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF07690 MFS_1 64 → 424 Major Facilitator Superfamily Family
Tissue specificity TISSUE SPECIFICITY: Detected in intestine and pancreas. Lower expression is also detected in liver and kidney. {ECO:0000269|PubMed:21949678}.
Sequence
Sequence length 501
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
Reactome Pathway
Gluconeogenesis
Associated diseases Disease associations from ClinVar (causal & non-causal) and other databases (OMIM, Orphanet, GWAS, etc.).
1
Evidence Score: ★☆☆☆☆  Gene-disease association found in Text Mining only ★★☆☆☆  Found in Text Mining and Unknown/Other Associations ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
Phenotype Name Clinical Significance Source Reference Evidence Score
Cervical cancer Uncertain significance ClinVar —
★★★★★
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
Associations from Text Mining Disease associations identified through text mining
Show/Hide Text Mining Associations (10)
Disease Name Disease (Merged) Source PMID Relationship Type Evidence Score
Brain Neoplasms Brain neoplasms Pubtator 38034009 Associate
★★★★★
★☆☆☆☆
Found in Text Mining only
Breast Carcinoma Breast Carcinoma BEFREE 28412963
★★★★★
★☆☆☆☆
Found in Text Mining only
Breast Neoplasms Breast neoplasm Pubtator 28412963 Associate
★★★★★
★☆☆☆☆
Found in Text Mining only
Carcinoma Hepatocellular Hepatocellular carcinoma Pubtator 35027829 Associate
★★★★★
★☆☆☆☆
Found in Text Mining only
Cortical Congenital Hyperostosis Cortical Congenital Hyperostosis BEFREE 27187611
★★★★★
★☆☆☆☆
Found in Text Mining only
Esophageal Squamous Cell Carcinoma Esophageal squamous cell carcinoma Pubtator 35789548 Associate
★★★★★
★☆☆☆☆
Found in Text Mining only
Glioblastoma Glioblastoma Pubtator 38034009 Associate
★★★★★
★☆☆☆☆
Found in Text Mining only
Hypoxia Hypoxia Pubtator 35789548 Associate
★★★★★
★☆☆☆☆
Found in Text Mining only
Malignant neoplasm of breast Breast Cancer BEFREE 28412963
★★★★★
★☆☆☆☆
Found in Text Mining only
Stomach Neoplasms Stomach neoplasms Pubtator 38035067 Associate
★★★★★
★☆☆☆☆
Found in Text Mining only