Gene Gene information from NCBI Gene database. Download as csv Download as pdf
Entrez ID	159371
Gene name	Solute carrier family 35 member G1
Gene symbol	SLC35G1
Synonyms (NCBI Gene)	C10orf60POSTTMEM20
Chromosome	10
Chromosome location	10q23.33
Summary	This gene encodes a transmembrane protein which is a member of the drug/metabolite transporter protein superfamily. The encoded protein may play a role in the regulation of calcium levels inside the cell. [provided by RefSeq, Sep 2016]

145 Show/Hide all (145)

miRTarBase ID	miRNA	Experiments	Reference
MIRT016560	hsa-miR-193b-3p	Microarray	20304954
MIRT019638	hsa-miR-340-5p	Sequencing	20371350
MIRT023045	hsa-miR-124-3p	Microarray	18668037
MIRT024861	hsa-miR-215-5p	Microarray	19074876
MIRT026852	hsa-miR-192-5p	Microarray	19074876
MIRT619036	hsa-miR-3150a-5p	HITS-CLIP	23824327
MIRT619035	hsa-miR-3150b-5p	HITS-CLIP	23824327
MIRT619034	hsa-miR-208a-5p	HITS-CLIP	23824327
MIRT619033	hsa-miR-208b-5p	HITS-CLIP	23824327
MIRT619032	hsa-miR-6814-5p	HITS-CLIP	23824327
MIRT619031	hsa-miR-150-5p	HITS-CLIP	23824327
MIRT619030	hsa-miR-627-3p	HITS-CLIP	23824327
MIRT619029	hsa-miR-6831-3p	HITS-CLIP	23824327
MIRT619028	hsa-miR-518d-5p	HITS-CLIP	23824327
MIRT619027	hsa-miR-518e-5p	HITS-CLIP	23824327
MIRT619026	hsa-miR-518f-5p	HITS-CLIP	23824327
MIRT619025	hsa-miR-519a-5p	HITS-CLIP	23824327
MIRT619024	hsa-miR-519b-5p	HITS-CLIP	23824327
MIRT619023	hsa-miR-519c-5p	HITS-CLIP	23824327
MIRT619022	hsa-miR-520c-5p	HITS-CLIP	23824327
MIRT619021	hsa-miR-522-5p	HITS-CLIP	23824327
MIRT619020	hsa-miR-523-5p	HITS-CLIP	23824327
MIRT619019	hsa-miR-526a	HITS-CLIP	23824327
MIRT619018	hsa-miR-4777-5p	HITS-CLIP	23824327
MIRT619036	hsa-miR-3150a-5p	HITS-CLIP	23824327
MIRT619035	hsa-miR-3150b-5p	HITS-CLIP	23824327
MIRT619034	hsa-miR-208a-5p	HITS-CLIP	23824327
MIRT619033	hsa-miR-208b-5p	HITS-CLIP	23824327
MIRT619032	hsa-miR-6814-5p	HITS-CLIP	23824327
MIRT619031	hsa-miR-150-5p	HITS-CLIP	23824327
MIRT619030	hsa-miR-627-3p	HITS-CLIP	23824327
MIRT619029	hsa-miR-6831-3p	HITS-CLIP	23824327
MIRT619028	hsa-miR-518d-5p	HITS-CLIP	23824327
MIRT619027	hsa-miR-518e-5p	HITS-CLIP	23824327
MIRT619026	hsa-miR-518f-5p	HITS-CLIP	23824327
MIRT619025	hsa-miR-519a-5p	HITS-CLIP	23824327
MIRT619024	hsa-miR-519b-5p	HITS-CLIP	23824327
MIRT619023	hsa-miR-519c-5p	HITS-CLIP	23824327
MIRT619022	hsa-miR-520c-5p	HITS-CLIP	23824327
MIRT619021	hsa-miR-522-5p	HITS-CLIP	23824327
MIRT619020	hsa-miR-523-5p	HITS-CLIP	23824327
MIRT619019	hsa-miR-526a	HITS-CLIP	23824327
MIRT619018	hsa-miR-4777-5p	HITS-CLIP	23824327
MIRT565609	hsa-miR-4319	PAR-CLIP	20371350
MIRT565608	hsa-miR-125b-5p	PAR-CLIP	20371350
MIRT565607	hsa-miR-125a-5p	PAR-CLIP	20371350
MIRT443323	hsa-miR-4760-3p	PAR-CLIP	20371350
MIRT565606	hsa-miR-6854-5p	PAR-CLIP	20371350
MIRT565605	hsa-miR-3927-3p	PAR-CLIP	20371350
MIRT565604	hsa-miR-6831-5p	PAR-CLIP	20371350
MIRT565603	hsa-miR-196a-5p	PAR-CLIP	20371350
MIRT565602	hsa-miR-196b-5p	PAR-CLIP	20371350
MIRT565601	hsa-miR-345-3p	PAR-CLIP	20371350
MIRT565600	hsa-miR-4732-3p	PAR-CLIP	20371350
MIRT565599	hsa-miR-4324	PAR-CLIP	20371350
MIRT565598	hsa-miR-6761-5p	PAR-CLIP	20371350
MIRT565597	hsa-miR-4693-3p	PAR-CLIP	20371350
MIRT565596	hsa-miR-4424	PAR-CLIP	20371350
MIRT565595	hsa-miR-7-5p	PAR-CLIP	20371350
MIRT565594	hsa-miR-6077	PAR-CLIP	20371350
MIRT565593	hsa-miR-23a-5p	PAR-CLIP	20371350
MIRT565592	hsa-miR-23b-5p	PAR-CLIP	20371350
MIRT565591	hsa-miR-642b-5p	PAR-CLIP	20371350
MIRT565590	hsa-miR-331-5p	PAR-CLIP	20371350
MIRT565589	hsa-miR-670-5p	PAR-CLIP	20371350
MIRT565588	hsa-miR-6509-5p	PAR-CLIP	20371350
MIRT534222	hsa-miR-7844-5p	PAR-CLIP	22012620
MIRT534221	hsa-miR-302a-5p	PAR-CLIP	22012620
MIRT534220	hsa-miR-6715b-3p	PAR-CLIP	22012620
MIRT443325	hsa-miR-4753-5p	PAR-CLIP	22100165
MIRT443326	hsa-miR-500a-5p	PAR-CLIP	22100165
MIRT443323	hsa-miR-4760-3p	PAR-CLIP	22100165
MIRT443324	hsa-miR-362-5p	PAR-CLIP	22100165
MIRT443322	hsa-miR-500b-5p	PAR-CLIP	22100165
MIRT443321	hsa-miR-664a-3p	PAR-CLIP	22100165
MIRT619036	hsa-miR-3150a-5p	HITS-CLIP	23824327
MIRT619035	hsa-miR-3150b-5p	HITS-CLIP	23824327
MIRT619034	hsa-miR-208a-5p	HITS-CLIP	23824327
MIRT619033	hsa-miR-208b-5p	HITS-CLIP	23824327
MIRT619032	hsa-miR-6814-5p	HITS-CLIP	23824327
MIRT619031	hsa-miR-150-5p	HITS-CLIP	23824327
MIRT619030	hsa-miR-627-3p	HITS-CLIP	23824327
MIRT619029	hsa-miR-6831-3p	HITS-CLIP	23824327
MIRT619028	hsa-miR-518d-5p	HITS-CLIP	23824327
MIRT619027	hsa-miR-518e-5p	HITS-CLIP	23824327
MIRT619026	hsa-miR-518f-5p	HITS-CLIP	23824327
MIRT619025	hsa-miR-519a-5p	HITS-CLIP	23824327
MIRT619024	hsa-miR-519b-5p	HITS-CLIP	23824327
MIRT619023	hsa-miR-519c-5p	HITS-CLIP	23824327
MIRT619022	hsa-miR-520c-5p	HITS-CLIP	23824327
MIRT619021	hsa-miR-522-5p	HITS-CLIP	23824327
MIRT619020	hsa-miR-523-5p	HITS-CLIP	23824327
MIRT619019	hsa-miR-526a	HITS-CLIP	23824327
MIRT619018	hsa-miR-4777-5p	HITS-CLIP	23824327
MIRT619036	hsa-miR-3150a-5p	HITS-CLIP	23824327
MIRT619035	hsa-miR-3150b-5p	HITS-CLIP	23824327
MIRT619034	hsa-miR-208a-5p	HITS-CLIP	23824327
MIRT619033	hsa-miR-208b-5p	HITS-CLIP	23824327
MIRT619032	hsa-miR-6814-5p	HITS-CLIP	23824327
MIRT619031	hsa-miR-150-5p	HITS-CLIP	23824327
MIRT619030	hsa-miR-627-3p	HITS-CLIP	23824327
MIRT619029	hsa-miR-6831-3p	HITS-CLIP	23824327
MIRT619028	hsa-miR-518d-5p	HITS-CLIP	23824327
MIRT619027	hsa-miR-518e-5p	HITS-CLIP	23824327
MIRT619026	hsa-miR-518f-5p	HITS-CLIP	23824327
MIRT619025	hsa-miR-519a-5p	HITS-CLIP	23824327
MIRT619024	hsa-miR-519b-5p	HITS-CLIP	23824327
MIRT619023	hsa-miR-519c-5p	HITS-CLIP	23824327
MIRT619022	hsa-miR-520c-5p	HITS-CLIP	23824327
MIRT619021	hsa-miR-522-5p	HITS-CLIP	23824327
MIRT619020	hsa-miR-523-5p	HITS-CLIP	23824327
MIRT619019	hsa-miR-526a	HITS-CLIP	23824327
MIRT619018	hsa-miR-4777-5p	HITS-CLIP	23824327
MIRT565609	hsa-miR-4319	PAR-CLIP	20371350
MIRT565608	hsa-miR-125b-5p	PAR-CLIP	20371350
MIRT565607	hsa-miR-125a-5p	PAR-CLIP	20371350
MIRT443323	hsa-miR-4760-3p	PAR-CLIP	20371350
MIRT565606	hsa-miR-6854-5p	PAR-CLIP	20371350
MIRT565605	hsa-miR-3927-3p	PAR-CLIP	20371350
MIRT565604	hsa-miR-6831-5p	PAR-CLIP	20371350
MIRT565603	hsa-miR-196a-5p	PAR-CLIP	20371350
MIRT565602	hsa-miR-196b-5p	PAR-CLIP	20371350
MIRT565601	hsa-miR-345-3p	PAR-CLIP	20371350
MIRT565600	hsa-miR-4732-3p	PAR-CLIP	20371350
MIRT565599	hsa-miR-4324	PAR-CLIP	20371350
MIRT565598	hsa-miR-6761-5p	PAR-CLIP	20371350
MIRT565597	hsa-miR-4693-3p	PAR-CLIP	20371350
MIRT565596	hsa-miR-4424	PAR-CLIP	20371350
MIRT565595	hsa-miR-7-5p	PAR-CLIP	20371350
MIRT565594	hsa-miR-6077	PAR-CLIP	20371350
MIRT565593	hsa-miR-23a-5p	PAR-CLIP	20371350
MIRT565592	hsa-miR-23b-5p	PAR-CLIP	20371350
MIRT565591	hsa-miR-642b-5p	PAR-CLIP	20371350
MIRT565590	hsa-miR-331-5p	PAR-CLIP	20371350
MIRT565589	hsa-miR-670-5p	PAR-CLIP	20371350
MIRT565588	hsa-miR-6509-5p	PAR-CLIP	20371350
MIRT534222	hsa-miR-7844-5p	PAR-CLIP	22012620
MIRT534221	hsa-miR-302a-5p	PAR-CLIP	22012620
MIRT534220	hsa-miR-6715b-3p	PAR-CLIP	22012620
MIRT443325	hsa-miR-4753-5p	PAR-CLIP	22100165
MIRT443326	hsa-miR-500a-5p	PAR-CLIP	22100165
MIRT443323	hsa-miR-4760-3p	PAR-CLIP	22100165
MIRT443324	hsa-miR-362-5p	PAR-CLIP	22100165
MIRT443322	hsa-miR-500b-5p	PAR-CLIP	22100165
MIRT443321	hsa-miR-664a-3p	PAR-CLIP	22100165

13 Show/Hide all (13)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005515	Function	Protein binding	IPI	22084111, 32296183
GO:0005783	Component	Endoplasmic reticulum	IEA
GO:0005789	Component	Endoplasmic reticulum membrane	IBA
GO:0005789	Component	Endoplasmic reticulum membrane	IDA	22084111
GO:0005789	Component	Endoplasmic reticulum membrane	IEA
GO:0005886	Component	Plasma membrane	IBA
GO:0005886	Component	Plasma membrane	IDA	22084111
GO:0005886	Component	Plasma membrane	IEA
GO:0016020	Component	Membrane	IEA
GO:0051480	Process	Regulation of cytosolic calcium ion concentration	IBA
GO:0051480	Process	Regulation of cytosolic calcium ion concentration	IMP	22084111
GO:1990034	Process	Calcium ion export across plasma membrane	IBA
GO:1990034	Process	Calcium ion export across plasma membrane	IMP	22084111

MIM	HGNC	e!Ensembl
617167	26607	ENSG00000176273

Q2M3R5

Protein name

Solute carrier family 35 member G1 (Partner of STIM1) (Transmembrane protein 20)

Protein function

May play a role in intracellular calcium sensing and homeostasis. May act as a negative regulator of plasma membrane calcium-transporting ATPases preventing calcium efflux from the cell.

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00892	EamA	69 → 202	EamA-like transporter family	Family
PF00892	EamA	222 → 356	EamA-like transporter family	Family

Tissue specificity

TISSUE SPECIFICITY: Ubiquitously expressed. {ECO:0000269|PubMed:22084111}.

Sequence

MRPQDSTGVAELQEPGLPLTDDAPPGATEEPAAAEAAGAPDRGRCWLCLSSPCCSRTEPE
AKKKAPCPGLGLFYTLLSAFLFSVGSLFVKKVQDVHAVEISAFRCVFQMLVVIPCLIYRK
TGFIGPKGQRIFLILRGVLGSTAMMLIYYAYQTMSLADATVITFSSPVFTSIFAWICLKE
KYSPWDALFTVFTITGVILIVRPPFLFGSDTSGMEESYSGHLKGTFAAIGSAVFAASTLV
ILRKMGKSVDYFLSIWYYVVLGLVESVIILSVLGEWSLPYCGLDRLFLIFIGLFGLGGQI
FITKALQIEKAGPVAIMKTMDVVFAFIFQIIFFNNVPTWWTVGGALCVVASNVGAAIRKW
YQSSK

Sequence length

365

Interactions

View interactions

Evidence Score: ★☆☆☆☆ Gene-disease association found in Text Mining only ★★☆☆☆ Found in Text Mining and Unknown/Other Associations ★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Phenotype Name	Clinical Significance	Source	Reference	Evidence Score
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
Prostate cancer	Uncertain significance	ClinVar	—	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Associations from Text Mining Disease associations identified through text mining Show/Hide Text Mining Associations (43)
Atrial Fibrillation	Atrial Fibrillation	BEFREE	28459661		★★★★★ ★☆☆☆☆ Found in Text Mining only
Autistic Disorder	Autism	BEFREE	24485488		★★★★★ ★☆☆☆☆ Found in Text Mining only
Breast Carcinoma	Breast Carcinoma	BEFREE	25366766		★★★★★ ★☆☆☆☆ Found in Text Mining only
Colorectal Carcinoma	Colorectal Cancer	BEFREE	12537654		★★★★★ ★☆☆☆☆ Found in Text Mining only
Coronary Arteriosclerosis	Coronary Arteriosclerosis	BEFREE	25460367		★★★★★ ★☆☆☆☆ Found in Text Mining only
Cutis laxa, x-linked	Cutis Laxa, X-Linked	BEFREE	26923628		★★★★★ ★☆☆☆☆ Found in Text Mining only
Depressive disorder	Mental Depression	BEFREE	20943350, 28459660		★★★★★ ★☆☆☆☆ Found in Text Mining only
Dermatitis, Atopic	Dermatitis	BEFREE	28459659		★★★★★ ★☆☆☆☆ Found in Text Mining only
Diabetes	Diabetes	BEFREE	19179458, 27967228, 3898763		★★★★★ ★☆☆☆☆ Found in Text Mining only
Diabetes Mellitus	Diabetes Mellitus	BEFREE	19179458, 27967228, 3898763		★★★★★ ★☆☆☆☆ Found in Text Mining only
Diabetes Mellitus, Insulin-Dependent	Diabetes Mellitus	BEFREE	29749032		★★★★★ ★☆☆☆☆ Found in Text Mining only
Diabetes Mellitus, Non-Insulin-Dependent	Diabetes Mellitus	BEFREE	3898763, 3898767		★★★★★ ★☆☆☆☆ Found in Text Mining only
Eczema	Eczema	BEFREE	28459659		★★★★★ ★☆☆☆☆ Found in Text Mining only
Epilepsy	Epilepsy	BEFREE	28768851		★★★★★ ★☆☆☆☆ Found in Text Mining only
Hemolytic-Uremic Syndrome	Hemolytic Uremic Syndrome	BEFREE	16427809		★★★★★ ★☆☆☆☆ Found in Text Mining only
Hepatoblastoma	Hepatoblastoma	BEFREE	27501172		★★★★★ ★☆☆☆☆ Found in Text Mining only
Hyperglycemia	Hyperglycemia	BEFREE	3898763		★★★★★ ★☆☆☆☆ Found in Text Mining only
Insulin-Like Growth Factor I Deficiency	Insulin-Like Growth Factor I Deficiency	BEFREE	10549306		★★★★★ ★☆☆☆☆ Found in Text Mining only
Intussusception	Intussusception	BEFREE	28926507		★★★★★ ★☆☆☆☆ Found in Text Mining only
Kidney Failure	Kidney Failure	BEFREE	16427809		★★★★★ ★☆☆☆☆ Found in Text Mining only
Laron Syndrome	Laron Syndrome	BEFREE	17598975		★★★★★ ★☆☆☆☆ Found in Text Mining only
leukemia	Leukemia	BEFREE	8049644		★★★★★ ★☆☆☆☆ Found in Text Mining only
Leukemia, Myelocytic, Acute	Leukemia	BEFREE	8806691		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of breast	Breast Cancer	BEFREE	25366766		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of prostate	Prostate cancer	BEFREE	24948870		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant Neoplasms	Malignant Neoplasm	BEFREE	16176873, 31851005		★★★★★ ★☆☆☆☆ Found in Text Mining only
Mental Depression	Mental Depression	BEFREE	20943350, 28459660		★★★★★ ★☆☆☆☆ Found in Text Mining only
Metastatic melanoma	Metastatic Melanoma	BEFREE	29023264		★★★★★ ★☆☆☆☆ Found in Text Mining only
Mucopolysaccharidosis II	Mucopolysaccharidosis	BEFREE	30994022		★★★★★ ★☆☆☆☆ Found in Text Mining only
MYELOPROLIFERATIVE SYNDROME, TRANSIENT	Myeloproliferative disorder	BEFREE	27580154		★★★★★ ★☆☆☆☆ Found in Text Mining only
Myocardial Ischemia	Myocardial Ischemia	BEFREE	25460367		★★★★★ ★☆☆☆☆ Found in Text Mining only
Myotonic Dystrophy	Myotonic dystrophy	BEFREE	28915272		★★★★★ ★☆☆☆☆ Found in Text Mining only
Neoplasms	Neoplasms	BEFREE	27501172		★★★★★ ★☆☆☆☆ Found in Text Mining only
Obesity	Obesity	BEFREE	11596667		★★★★★ ★☆☆☆☆ Found in Text Mining only
Osteoarthritis	Osteoarthritis	Pubtator	35093162	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Polycystic Ovary Syndrome	Polycystic Ovary Syndrome	BEFREE	17719609		★★★★★ ★☆☆☆☆ Found in Text Mining only
Primary immune deficiency disorder	immunodeficiency	BEFREE	15135774		★★★★★ ★☆☆☆☆ Found in Text Mining only
Prostate carcinoma	Prostate cancer	BEFREE	24948870		★★★★★ ★☆☆☆☆ Found in Text Mining only
Schizophrenia	Schizophrenia	BEFREE	18693083, 19540875		★★★★★ ★☆☆☆☆ Found in Text Mining only
Sensorineural Hearing Loss (disorder)	Hearing Loss	BEFREE	31507391		★★★★★ ★☆☆☆☆ Found in Text Mining only
ST segment elevation myocardial infarction	ST Segment Elevation Myocardial Infarction	BEFREE	30519807		★★★★★ ★☆☆☆☆ Found in Text Mining only
STOMATOCYTOSIS I	Stomatocytosis	BEFREE	26923628		★★★★★ ★☆☆☆☆ Found in Text Mining only
Werner Syndrome	Werner Syndrome	BEFREE	7736897		★★★★★ ★☆☆☆☆ Found in Text Mining only

Related Genes Genes most often co-reported with SLC35G1 across shared curated disease and pathway associations. 0 Download as csv Download as pdf
No strongly related genes found yet for SLC35G1.

Diseases Linked via Similar Genes Diseases curated for genes most similar to SLC35G1 (see Related Genes above), that are NOT already directly curated for SLC35G1 itself -- a lead worth checking, not a confirmed association. 0 Download as csv Download as pdf
No additional diseases found yet through genes similar to SLC35G1.

SLC35G1 (solute carrier family 35 member G1)

Save This Analysis