SH3BGRL (SH3 domain binding glutamate rich protein like)

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Gene miRNA Gene ontology Other IDs Protein Related genes Diseases linked via similar genes

Gene

• Entrez ID: 6451
• Gene name: SH3 domain binding glutamate rich protein like
• Gene symbol: SH3BGRL
• Synonyms (NCBI Gene): HEL-S-115, SH3BGR
• Chromosome: X
• Chromosome location: Xq21.1

miRNA Show/Hide all (281)

miRTarBase ID	miRNA	Experiments	Reference
MIRT021777	hsa-miR-132-3p	Microarray	17612493
MIRT022023	hsa-miR-128-3p	Microarray	17612493
MIRT025132	hsa-miR-181a-5p	Microarray	17612493
MIRT054210	hsa-miR-210-3p	Luciferase reporter assay, Microarray, qRT-PCR, Western blot	23028679
MIRT230064	hsa-miR-548a-5p	PAR-CLIP	21572407
MIRT230075	hsa-miR-548ab	PAR-CLIP	21572407
MIRT230076	hsa-miR-548ad-5p	PAR-CLIP	21572407
MIRT230077	hsa-miR-548ae-5p	PAR-CLIP	21572407
MIRT230078	hsa-miR-548ak	PAR-CLIP	21572407
MIRT230079	hsa-miR-548am-5p	PAR-CLIP	21572407
MIRT230082	hsa-miR-548ap-5p	PAR-CLIP	21572407
MIRT230083	hsa-miR-548aq-5p	PAR-CLIP	21572407
MIRT230084	hsa-miR-548ar-5p	PAR-CLIP	21572407
MIRT230085	hsa-miR-548as-5p	PAR-CLIP	21572407
MIRT230086	hsa-miR-548au-5p	PAR-CLIP	21572407
MIRT230088	hsa-miR-548ay-5p	PAR-CLIP	21572407
MIRT230063	hsa-miR-548b-5p	PAR-CLIP	21572407
MIRT230091	hsa-miR-548bb-5p	PAR-CLIP	21572407
MIRT230065	hsa-miR-548c-5p	PAR-CLIP	21572407
MIRT230066	hsa-miR-548d-5p	PAR-CLIP	21572407
MIRT230068	hsa-miR-548h-5p	PAR-CLIP	21572407
MIRT230069	hsa-miR-548i	PAR-CLIP	21572407
MIRT230067	hsa-miR-548j-5p	PAR-CLIP	21572407
MIRT230074	hsa-miR-548o-5p	PAR-CLIP	21572407
MIRT230071	hsa-miR-548w	PAR-CLIP	21572407
MIRT230073	hsa-miR-548y	PAR-CLIP	21572407
MIRT230062	hsa-miR-559	PAR-CLIP	21572407
MIRT544151	hsa-miR-548av-5p	PAR-CLIP	21572407
MIRT544150	hsa-miR-548k	PAR-CLIP	21572407
MIRT544149	hsa-miR-8054	PAR-CLIP	21572407
MIRT544148	hsa-miR-548l	PAR-CLIP	21572407
MIRT230089	hsa-miR-7852-3p	PAR-CLIP	21572407
MIRT544147	hsa-miR-3140-3p	PAR-CLIP	21572407
MIRT230081	hsa-miR-4703-3p	PAR-CLIP	21572407
MIRT544146	hsa-miR-6885-3p	PAR-CLIP	21572407
MIRT496331	hsa-miR-4717-5p	PAR-CLIP	22291592
MIRT496330	hsa-miR-15a-3p	PAR-CLIP	22291592
MIRT496329	hsa-miR-4781-3p	PAR-CLIP	22291592
MIRT496328	hsa-miR-4716-5p	PAR-CLIP	22291592
MIRT496327	hsa-miR-5704	PAR-CLIP	22291592
MIRT496326	hsa-miR-1295a	PAR-CLIP	22291592
MIRT496325	hsa-miR-487a-5p	PAR-CLIP	22291592
MIRT496324	hsa-miR-487b-5p	PAR-CLIP	22291592
MIRT054210	hsa-miR-210-3p	HITS-CLIP	22473208
MIRT054210	hsa-miR-210-3p	HITS-CLIP	22473208
MIRT230064	hsa-miR-548a-5p	PAR-CLIP	21572407
MIRT230075	hsa-miR-548ab	PAR-CLIP	21572407
MIRT230076	hsa-miR-548ad-5p	PAR-CLIP	21572407
MIRT230077	hsa-miR-548ae-5p	PAR-CLIP	21572407
MIRT230078	hsa-miR-548ak	PAR-CLIP	21572407
MIRT230079	hsa-miR-548am-5p	PAR-CLIP	21572407
MIRT230082	hsa-miR-548ap-5p	PAR-CLIP	21572407
MIRT230083	hsa-miR-548aq-5p	PAR-CLIP	21572407
MIRT230084	hsa-miR-548ar-5p	PAR-CLIP	21572407
MIRT230085	hsa-miR-548as-5p	PAR-CLIP	21572407
MIRT230086	hsa-miR-548au-5p	PAR-CLIP	21572407
MIRT230088	hsa-miR-548ay-5p	PAR-CLIP	21572407
MIRT230063	hsa-miR-548b-5p	PAR-CLIP	21572407
MIRT230091	hsa-miR-548bb-5p	PAR-CLIP	21572407
MIRT230065	hsa-miR-548c-5p	PAR-CLIP	21572407
MIRT230066	hsa-miR-548d-5p	PAR-CLIP	21572407
MIRT230068	hsa-miR-548h-5p	PAR-CLIP	21572407
MIRT230069	hsa-miR-548i	PAR-CLIP	21572407
MIRT230067	hsa-miR-548j-5p	PAR-CLIP	21572407
MIRT230074	hsa-miR-548o-5p	PAR-CLIP	21572407
MIRT230071	hsa-miR-548w	PAR-CLIP	21572407
MIRT230073	hsa-miR-548y	PAR-CLIP	21572407
MIRT230062	hsa-miR-559	PAR-CLIP	21572407
MIRT544151	hsa-miR-548av-5p	PAR-CLIP	21572407
MIRT544150	hsa-miR-548k	PAR-CLIP	21572407
MIRT544149	hsa-miR-8054	PAR-CLIP	21572407
MIRT544148	hsa-miR-548l	PAR-CLIP	21572407
MIRT230089	hsa-miR-7852-3p	PAR-CLIP	21572407
MIRT544147	hsa-miR-3140-3p	PAR-CLIP	21572407
MIRT230081	hsa-miR-4703-3p	PAR-CLIP	21572407
MIRT544146	hsa-miR-6885-3p	PAR-CLIP	21572407
MIRT496331	hsa-miR-4717-5p	PAR-CLIP	22291592
MIRT496330	hsa-miR-15a-3p	PAR-CLIP	22291592
MIRT496329	hsa-miR-4781-3p	PAR-CLIP	22291592
MIRT496328	hsa-miR-4716-5p	PAR-CLIP	22291592
MIRT496327	hsa-miR-5704	PAR-CLIP	22291592
MIRT496326	hsa-miR-1295a	PAR-CLIP	22291592
MIRT496325	hsa-miR-487a-5p	PAR-CLIP	22291592
MIRT496324	hsa-miR-487b-5p	PAR-CLIP	22291592
MIRT1344459	hsa-miR-129-5p	CLIP-seq
MIRT1344460	hsa-miR-154	CLIP-seq
MIRT1344461	hsa-miR-3682-5p	CLIP-seq
MIRT1344462	hsa-miR-4279	CLIP-seq
MIRT1344463	hsa-miR-4753-3p	CLIP-seq
MIRT1344464	hsa-miR-4768-5p	CLIP-seq
MIRT1344465	hsa-miR-548n	CLIP-seq
MIRT1344466	hsa-miR-548t	CLIP-seq
MIRT1553641	hsa-miR-1261	CLIP-seq
MIRT1553642	hsa-miR-1827	CLIP-seq
MIRT1553643	hsa-miR-3074-3p	CLIP-seq
MIRT1553644	hsa-miR-3201	CLIP-seq
MIRT1553645	hsa-miR-448	CLIP-seq
MIRT1553646	hsa-miR-4791	CLIP-seq
MIRT1553647	hsa-miR-586	CLIP-seq
MIRT1553648	hsa-miR-890	CLIP-seq
MIRT2101827	hsa-miR-1206	CLIP-seq
MIRT2101828	hsa-miR-3647-3p	CLIP-seq
MIRT2101829	hsa-miR-433	CLIP-seq
MIRT2326286	hsa-miR-103b	CLIP-seq
MIRT2326287	hsa-miR-1271	CLIP-seq
MIRT2326288	hsa-miR-182	CLIP-seq
MIRT1553643	hsa-miR-3074-3p	CLIP-seq
MIRT2326289	hsa-miR-3202	CLIP-seq
MIRT2326290	hsa-miR-34b	CLIP-seq
MIRT2326291	hsa-miR-4470	CLIP-seq
MIRT1553645	hsa-miR-448	CLIP-seq
MIRT2326292	hsa-miR-4668-3p	CLIP-seq
MIRT2326293	hsa-miR-548h	CLIP-seq
MIRT2326294	hsa-miR-548j	CLIP-seq
MIRT1344465	hsa-miR-548n	CLIP-seq
MIRT1553648	hsa-miR-890	CLIP-seq
MIRT2326295	hsa-miR-96	CLIP-seq
MIRT2621922	hsa-miR-1	CLIP-seq
MIRT2326286	hsa-miR-103b	CLIP-seq
MIRT2621923	hsa-miR-1179	CLIP-seq
MIRT2621924	hsa-miR-1236	CLIP-seq
MIRT1553641	hsa-miR-1261	CLIP-seq
MIRT2621925	hsa-miR-1264	CLIP-seq
MIRT2326287	hsa-miR-1271	CLIP-seq
MIRT2621926	hsa-miR-1273g	CLIP-seq
MIRT2621927	hsa-miR-1283	CLIP-seq
MIRT2621928	hsa-miR-1295	CLIP-seq
MIRT2621929	hsa-miR-1323	CLIP-seq
MIRT2326288	hsa-miR-182	CLIP-seq
MIRT1553642	hsa-miR-1827	CLIP-seq
MIRT2621930	hsa-miR-186	CLIP-seq
MIRT2621931	hsa-miR-19a	CLIP-seq
MIRT2621932	hsa-miR-19b	CLIP-seq
MIRT2621933	hsa-miR-203	CLIP-seq
MIRT2621934	hsa-miR-206	CLIP-seq
MIRT2621935	hsa-miR-219-1-3p	CLIP-seq
MIRT2621936	hsa-miR-221	CLIP-seq
MIRT2621937	hsa-miR-222	CLIP-seq
MIRT1553643	hsa-miR-3074-3p	CLIP-seq
MIRT2621938	hsa-miR-3143	CLIP-seq
MIRT2621939	hsa-miR-3155	CLIP-seq
MIRT2621940	hsa-miR-3155b	CLIP-seq
MIRT2621941	hsa-miR-3157-3p	CLIP-seq
MIRT1553644	hsa-miR-3201	CLIP-seq
MIRT2621942	hsa-miR-323-3p	CLIP-seq
MIRT2621943	hsa-miR-338-3p	CLIP-seq
MIRT2621944	hsa-miR-338-5p	CLIP-seq
MIRT2621945	hsa-miR-3655	CLIP-seq
MIRT2621946	hsa-miR-3668	CLIP-seq
MIRT2621947	hsa-miR-374a	CLIP-seq
MIRT2621948	hsa-miR-374b	CLIP-seq
MIRT2621949	hsa-miR-374c	CLIP-seq
MIRT2621950	hsa-miR-380	CLIP-seq
MIRT2621951	hsa-miR-3910	CLIP-seq
MIRT2326291	hsa-miR-4470	CLIP-seq
MIRT2621952	hsa-miR-4495	CLIP-seq
MIRT2621953	hsa-miR-4496	CLIP-seq
MIRT2621954	hsa-miR-4528	CLIP-seq
MIRT2621955	hsa-miR-4662a-3p	CLIP-seq
MIRT2621956	hsa-miR-4666-3p	CLIP-seq
MIRT2621957	hsa-miR-4738-3p	CLIP-seq
MIRT2621958	hsa-miR-4766-3p	CLIP-seq
MIRT1553646	hsa-miR-4791	CLIP-seq
MIRT2621959	hsa-miR-4802-3p	CLIP-seq
MIRT2621960	hsa-miR-4803	CLIP-seq
MIRT2621961	hsa-miR-484	CLIP-seq
MIRT2621962	hsa-miR-485-3p	CLIP-seq
MIRT2621963	hsa-miR-487a	CLIP-seq
MIRT2621964	hsa-miR-488	CLIP-seq
MIRT2621965	hsa-miR-494	CLIP-seq
MIRT2621966	hsa-miR-511	CLIP-seq
MIRT2621967	hsa-miR-548ae	CLIP-seq
MIRT2621968	hsa-miR-548ag	CLIP-seq
MIRT2621969	hsa-miR-548ai	CLIP-seq
MIRT2621970	hsa-miR-548aj	CLIP-seq
MIRT2621971	hsa-miR-548am	CLIP-seq
MIRT2621972	hsa-miR-548an	CLIP-seq
MIRT2621973	hsa-miR-548g	CLIP-seq
MIRT2326293	hsa-miR-548h	CLIP-seq
MIRT2326294	hsa-miR-548j	CLIP-seq
MIRT2621974	hsa-miR-548m	CLIP-seq
MIRT1344465	hsa-miR-548n	CLIP-seq
MIRT2621975	hsa-miR-548o	CLIP-seq
MIRT2621976	hsa-miR-548p	CLIP-seq
MIRT1344466	hsa-miR-548t	CLIP-seq
MIRT2621977	hsa-miR-548u	CLIP-seq
MIRT2621978	hsa-miR-548x	CLIP-seq
MIRT2621979	hsa-miR-553	CLIP-seq
MIRT2621980	hsa-miR-571	CLIP-seq
MIRT2621981	hsa-miR-578	CLIP-seq
MIRT2621982	hsa-miR-606	CLIP-seq
MIRT2621983	hsa-miR-613	CLIP-seq
MIRT2621984	hsa-miR-634	CLIP-seq
MIRT2621985	hsa-miR-655	CLIP-seq
MIRT2621986	hsa-miR-874	CLIP-seq
MIRT2621987	hsa-miR-889	CLIP-seq
MIRT1553648	hsa-miR-890	CLIP-seq
MIRT2621988	hsa-miR-938	CLIP-seq
MIRT2326295	hsa-miR-96	CLIP-seq
MIRT2621922	hsa-miR-1	CLIP-seq
MIRT2326286	hsa-miR-103b	CLIP-seq
MIRT2621923	hsa-miR-1179	CLIP-seq
MIRT2621924	hsa-miR-1236	CLIP-seq
MIRT1553641	hsa-miR-1261	CLIP-seq
MIRT2621925	hsa-miR-1264	CLIP-seq
MIRT2326287	hsa-miR-1271	CLIP-seq
MIRT2621926	hsa-miR-1273g	CLIP-seq
MIRT2621927	hsa-miR-1283	CLIP-seq
MIRT2621928	hsa-miR-1295	CLIP-seq
MIRT2621929	hsa-miR-1323	CLIP-seq
MIRT2326288	hsa-miR-182	CLIP-seq
MIRT1553642	hsa-miR-1827	CLIP-seq
MIRT2621930	hsa-miR-186	CLIP-seq
MIRT2621931	hsa-miR-19a	CLIP-seq
MIRT2621932	hsa-miR-19b	CLIP-seq
MIRT2621933	hsa-miR-203	CLIP-seq
MIRT2621934	hsa-miR-206	CLIP-seq
MIRT2621935	hsa-miR-219-1-3p	CLIP-seq
MIRT2621936	hsa-miR-221	CLIP-seq
MIRT2621937	hsa-miR-222	CLIP-seq
MIRT1553643	hsa-miR-3074-3p	CLIP-seq
MIRT2621938	hsa-miR-3143	CLIP-seq
MIRT2621939	hsa-miR-3155	CLIP-seq
MIRT2621940	hsa-miR-3155b	CLIP-seq
MIRT2621941	hsa-miR-3157-3p	CLIP-seq
MIRT1553644	hsa-miR-3201	CLIP-seq
MIRT2621942	hsa-miR-323-3p	CLIP-seq
MIRT2621943	hsa-miR-338-3p	CLIP-seq
MIRT2621944	hsa-miR-338-5p	CLIP-seq
MIRT2621945	hsa-miR-3655	CLIP-seq
MIRT2621946	hsa-miR-3668	CLIP-seq
MIRT2621947	hsa-miR-374a	CLIP-seq
MIRT2621948	hsa-miR-374b	CLIP-seq
MIRT2621949	hsa-miR-374c	CLIP-seq
MIRT2621950	hsa-miR-380	CLIP-seq
MIRT2621951	hsa-miR-3910	CLIP-seq
MIRT2326291	hsa-miR-4470	CLIP-seq
MIRT2621952	hsa-miR-4495	CLIP-seq
MIRT2621953	hsa-miR-4496	CLIP-seq
MIRT2621954	hsa-miR-4528	CLIP-seq
MIRT2621955	hsa-miR-4662a-3p	CLIP-seq
MIRT2621956	hsa-miR-4666-3p	CLIP-seq
MIRT2621957	hsa-miR-4738-3p	CLIP-seq
MIRT2621958	hsa-miR-4766-3p	CLIP-seq
MIRT1553646	hsa-miR-4791	CLIP-seq
MIRT2621959	hsa-miR-4802-3p	CLIP-seq
MIRT2621960	hsa-miR-4803	CLIP-seq
MIRT2621961	hsa-miR-484	CLIP-seq
MIRT2621962	hsa-miR-485-3p	CLIP-seq
MIRT2621963	hsa-miR-487a	CLIP-seq
MIRT2621964	hsa-miR-488	CLIP-seq
MIRT2621965	hsa-miR-494	CLIP-seq
MIRT2621966	hsa-miR-511	CLIP-seq
MIRT2621967	hsa-miR-548ae	CLIP-seq
MIRT2621968	hsa-miR-548ag	CLIP-seq
MIRT2621969	hsa-miR-548ai	CLIP-seq
MIRT2621970	hsa-miR-548aj	CLIP-seq
MIRT2621971	hsa-miR-548am	CLIP-seq
MIRT2621972	hsa-miR-548an	CLIP-seq
MIRT2621973	hsa-miR-548g	CLIP-seq
MIRT2326293	hsa-miR-548h	CLIP-seq
MIRT2326294	hsa-miR-548j	CLIP-seq
MIRT2621974	hsa-miR-548m	CLIP-seq
MIRT1344465	hsa-miR-548n	CLIP-seq
MIRT2621975	hsa-miR-548o	CLIP-seq
MIRT2621976	hsa-miR-548p	CLIP-seq
MIRT1344466	hsa-miR-548t	CLIP-seq
MIRT2621977	hsa-miR-548u	CLIP-seq
MIRT2621978	hsa-miR-548x	CLIP-seq
MIRT2621979	hsa-miR-553	CLIP-seq
MIRT2621980	hsa-miR-571	CLIP-seq
MIRT2621981	hsa-miR-578	CLIP-seq
MIRT2621982	hsa-miR-606	CLIP-seq
MIRT2621983	hsa-miR-613	CLIP-seq
MIRT2621984	hsa-miR-634	CLIP-seq
MIRT2621985	hsa-miR-655	CLIP-seq
MIRT2621986	hsa-miR-874	CLIP-seq
MIRT2621987	hsa-miR-889	CLIP-seq
MIRT1553648	hsa-miR-890	CLIP-seq
MIRT2621988	hsa-miR-938	CLIP-seq
MIRT2326295	hsa-miR-96	CLIP-seq

Gene ontology (GO) Show/Hide all (16)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005615	Component	Extracellular space	HDA	23580065
GO:0005634	Component	Nucleus	IEA
GO:0005634	Component	Nucleus	TAS	16130169
GO:0005737	Component	Cytoplasm	IBA
GO:0005737	Component	Cytoplasm	IEA
GO:0005737	Component	Cytoplasm	TAS	16130169
GO:0005829	Component	Cytosol	IDA	34870550
GO:0005829	Component	Cytosol	IEA
GO:0005886	Component	Plasma membrane	IEA
GO:0016020	Component	Membrane	IEA
GO:0017124	Function	SH3 domain binding	IEA
GO:0043161	Process	Proteasome-mediated ubiquitin-dependent protein catabolic process	IMP	34331014
GO:0070062	Component	Extracellular exosome	HDA	19056867, 20458337
GO:0140517	Function	Protein-RNA adaptor activity	IMP	34331014
GO:1904690	Process	Positive regulation of cytoplasmic translational initiation	IMP	34331014
GO:1990756	Function	Ubiquitin-like ligase-substrate adaptor activity	IMP	34331014

Other IDs

• MIM: 300190
• HGNC: 10823
• e!Ensembl: ENSG00000131171

Protein

• UniProt ID: O75368
• Protein name: Adapter SH3BGRL (SH3 domain-binding glutamic acid-rich-like protein 1)
• Protein function: Appears to function as an adapter protein that bridges proteins together or proteins with mRNAs (PubMed:34331014). May function as a ubiquitin ligase-substrate adapter (PubMed:34331014, PubMed:34870550). Additionally, associates with translating
• PDB: 1U6T , 1WRY
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF04908	SH3BGR	1 → 98	SH3-binding, glutamic acid-rich protein	Family

• Tissue specificity: TISSUE SPECIFICITY: Ubiquitous. {ECO:0000269|PubMed:9642120}.
• Sequence:

  MVIRVYIASSSGSTAIKKKQQDVLGFLEANKIGFEEKDIAANEENRKWMRENVPENSRPA
  TGYPLPPQIFNESQYRGDYDAFFEARENNAVYAFLGLTAPPGSKEAEVQAKQQA

• Sequence length: 114

Related Genes

No strongly related genes found yet for SH3BGRL.

Diseases Linked via Similar Genes

No additional diseases found yet through genes similar to SH3BGRL.