SFXN2 (sideroflexin 2)

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Gene miRNA Gene ontology Other IDs Protein Related genes Diseases linked via similar genes

Gene

• Entrez ID: 118980
• Gene name: Sideroflexin 2
• Gene symbol: SFXN2
• Synonyms (NCBI Gene): SLC56A2
• Chromosome: 10
• Chromosome location: 10q24.32

miRNA Show/Hide all (232)

miRTarBase ID	miRNA	Experiments	Reference
MIRT016460	hsa-miR-193b-3p	Microarray	20304954
MIRT021800	hsa-miR-132-3p	Microarray	17612493
MIRT022080	hsa-miR-128-3p	Microarray	17612493
MIRT1342484	hsa-miR-1245b-3p	CLIP-seq
MIRT1342485	hsa-miR-1253	CLIP-seq
MIRT1342486	hsa-miR-1265	CLIP-seq
MIRT1342487	hsa-miR-1273e	CLIP-seq
MIRT1342488	hsa-miR-1273g	CLIP-seq
MIRT1342489	hsa-miR-128	CLIP-seq
MIRT1342490	hsa-miR-1324	CLIP-seq
MIRT1342491	hsa-miR-147	CLIP-seq
MIRT1342492	hsa-miR-150	CLIP-seq
MIRT1342493	hsa-miR-151-5p	CLIP-seq
MIRT1342494	hsa-miR-151b	CLIP-seq
MIRT1342495	hsa-miR-155	CLIP-seq
MIRT1342496	hsa-miR-15a	CLIP-seq
MIRT1342497	hsa-miR-15b	CLIP-seq
MIRT1342498	hsa-miR-16	CLIP-seq
MIRT1342499	hsa-miR-182	CLIP-seq
MIRT1342500	hsa-miR-195	CLIP-seq
MIRT1342501	hsa-miR-202	CLIP-seq
MIRT1342502	hsa-miR-2110	CLIP-seq
MIRT1342503	hsa-miR-24	CLIP-seq
MIRT1342504	hsa-miR-27a	CLIP-seq
MIRT1342505	hsa-miR-27b	CLIP-seq
MIRT1342506	hsa-miR-299-3p	CLIP-seq
MIRT1342507	hsa-miR-3074-3p	CLIP-seq
MIRT1342508	hsa-miR-3123	CLIP-seq
MIRT1342509	hsa-miR-3173-3p	CLIP-seq
MIRT1342510	hsa-miR-3177-3p	CLIP-seq
MIRT1342511	hsa-miR-3180-5p	CLIP-seq
MIRT1342512	hsa-miR-3185	CLIP-seq
MIRT1342513	hsa-miR-3190	CLIP-seq
MIRT1342514	hsa-miR-3197	CLIP-seq
MIRT1342515	hsa-miR-3202	CLIP-seq
MIRT1342516	hsa-miR-320e	CLIP-seq
MIRT1342517	hsa-miR-329	CLIP-seq
MIRT1342518	hsa-miR-33a	CLIP-seq
MIRT1342519	hsa-miR-33b	CLIP-seq
MIRT1342520	hsa-miR-34a	CLIP-seq
MIRT1342521	hsa-miR-34c-5p	CLIP-seq
MIRT1342522	hsa-miR-3605-5p	CLIP-seq
MIRT1342523	hsa-miR-3622a-3p	CLIP-seq
MIRT1342524	hsa-miR-3622b-3p	CLIP-seq
MIRT1342525	hsa-miR-362-3p	CLIP-seq
MIRT1342526	hsa-miR-365	CLIP-seq
MIRT1342527	hsa-miR-3657	CLIP-seq
MIRT1342528	hsa-miR-3681	CLIP-seq
MIRT1342529	hsa-miR-3688-5p	CLIP-seq
MIRT1342530	hsa-miR-3911	CLIP-seq
MIRT1342531	hsa-miR-3925-5p	CLIP-seq
MIRT1342532	hsa-miR-3929	CLIP-seq
MIRT1342533	hsa-miR-3941	CLIP-seq
MIRT1342534	hsa-miR-3942-3p	CLIP-seq
MIRT1342535	hsa-miR-3976	CLIP-seq
MIRT1342536	hsa-miR-424	CLIP-seq
MIRT1342537	hsa-miR-4257	CLIP-seq
MIRT1342538	hsa-miR-4271	CLIP-seq
MIRT1342539	hsa-miR-4284	CLIP-seq
MIRT1342540	hsa-miR-4312	CLIP-seq
MIRT1342541	hsa-miR-4419b	CLIP-seq
MIRT1342542	hsa-miR-4433	CLIP-seq
MIRT1342543	hsa-miR-4436b-3p	CLIP-seq
MIRT1342544	hsa-miR-4455	CLIP-seq
MIRT1342545	hsa-miR-4460	CLIP-seq
MIRT1342546	hsa-miR-4470	CLIP-seq
MIRT1342547	hsa-miR-4477b	CLIP-seq
MIRT1342548	hsa-miR-4478	CLIP-seq
MIRT1342549	hsa-miR-4491	CLIP-seq
MIRT1342550	hsa-miR-4492	CLIP-seq
MIRT1342551	hsa-miR-4498	CLIP-seq
MIRT1342552	hsa-miR-449a	CLIP-seq
MIRT1342553	hsa-miR-449b	CLIP-seq
MIRT1342554	hsa-miR-4505	CLIP-seq
MIRT1342555	hsa-miR-4524	CLIP-seq
MIRT1342556	hsa-miR-4533	CLIP-seq
MIRT1342557	hsa-miR-4649-3p	CLIP-seq
MIRT1342558	hsa-miR-4657	CLIP-seq
MIRT1342559	hsa-miR-4662a-5p	CLIP-seq
MIRT1342560	hsa-miR-4666-5p	CLIP-seq
MIRT1342561	hsa-miR-4667-5p	CLIP-seq
MIRT1342562	hsa-miR-4669	CLIP-seq
MIRT1342563	hsa-miR-4676-5p	CLIP-seq
MIRT1342564	hsa-miR-4687-3p	CLIP-seq
MIRT1342565	hsa-miR-4699-5p	CLIP-seq
MIRT1342566	hsa-miR-4700-5p	CLIP-seq
MIRT1342567	hsa-miR-4709-3p	CLIP-seq
MIRT1342568	hsa-miR-4722-5p	CLIP-seq
MIRT1342569	hsa-miR-4725-3p	CLIP-seq
MIRT1342570	hsa-miR-4727-3p	CLIP-seq
MIRT1342571	hsa-miR-4731-5p	CLIP-seq
MIRT1342572	hsa-miR-4746-5p	CLIP-seq
MIRT1342573	hsa-miR-4747-5p	CLIP-seq
MIRT1342574	hsa-miR-4761-3p	CLIP-seq
MIRT1342575	hsa-miR-4761-5p	CLIP-seq
MIRT1342576	hsa-miR-4764-5p	CLIP-seq
MIRT1342577	hsa-miR-4767	CLIP-seq
MIRT1342578	hsa-miR-4768-3p	CLIP-seq
MIRT1342579	hsa-miR-4795-5p	CLIP-seq
MIRT1342580	hsa-miR-4802-3p	CLIP-seq
MIRT1342581	hsa-miR-485-5p	CLIP-seq
MIRT1342582	hsa-miR-497	CLIP-seq
MIRT1342583	hsa-miR-498	CLIP-seq
MIRT1342584	hsa-miR-503	CLIP-seq
MIRT1342585	hsa-miR-520a-5p	CLIP-seq
MIRT1342586	hsa-miR-525-5p	CLIP-seq
MIRT1342587	hsa-miR-544b	CLIP-seq
MIRT1342588	hsa-miR-548b-3p	CLIP-seq
MIRT1342589	hsa-miR-548n	CLIP-seq
MIRT1342590	hsa-miR-548t	CLIP-seq
MIRT1342591	hsa-miR-555	CLIP-seq
MIRT1342592	hsa-miR-561	CLIP-seq
MIRT1342593	hsa-miR-569	CLIP-seq
MIRT1342594	hsa-miR-575	CLIP-seq
MIRT1342595	hsa-miR-587	CLIP-seq
MIRT1342596	hsa-miR-603	CLIP-seq
MIRT1342597	hsa-miR-609	CLIP-seq
MIRT1342598	hsa-miR-618	CLIP-seq
MIRT1342599	hsa-miR-644	CLIP-seq
MIRT1342600	hsa-miR-646	CLIP-seq
MIRT1342601	hsa-miR-762	CLIP-seq
MIRT1342602	hsa-miR-765	CLIP-seq
MIRT1342603	hsa-miR-891a	CLIP-seq
MIRT1342604	hsa-miR-940	CLIP-seq
MIRT2101304	hsa-miR-1238	CLIP-seq
MIRT1342484	hsa-miR-1245b-3p	CLIP-seq
MIRT2101305	hsa-miR-146b-3p	CLIP-seq
MIRT1342501	hsa-miR-202	CLIP-seq
MIRT1342503	hsa-miR-24	CLIP-seq
MIRT1342506	hsa-miR-299-3p	CLIP-seq
MIRT2101306	hsa-miR-3173-5p	CLIP-seq
MIRT1342512	hsa-miR-3185	CLIP-seq
MIRT1342520	hsa-miR-34a	CLIP-seq
MIRT1342521	hsa-miR-34c-5p	CLIP-seq
MIRT2101307	hsa-miR-3685	CLIP-seq
MIRT1342529	hsa-miR-3688-5p	CLIP-seq
MIRT2101308	hsa-miR-384	CLIP-seq
MIRT1342532	hsa-miR-3929	CLIP-seq
MIRT1342534	hsa-miR-3942-3p	CLIP-seq
MIRT1342537	hsa-miR-4257	CLIP-seq
MIRT1342539	hsa-miR-4284	CLIP-seq
MIRT1342541	hsa-miR-4419b	CLIP-seq
MIRT1342544	hsa-miR-4455	CLIP-seq
MIRT1342548	hsa-miR-4478	CLIP-seq
MIRT1342549	hsa-miR-4491	CLIP-seq
MIRT1342550	hsa-miR-4492	CLIP-seq
MIRT1342551	hsa-miR-4498	CLIP-seq
MIRT1342552	hsa-miR-449a	CLIP-seq
MIRT1342553	hsa-miR-449b	CLIP-seq
MIRT1342554	hsa-miR-4505	CLIP-seq
MIRT1342557	hsa-miR-4649-3p	CLIP-seq
MIRT1342558	hsa-miR-4657	CLIP-seq
MIRT2101309	hsa-miR-4685-5p	CLIP-seq
MIRT1342567	hsa-miR-4709-3p	CLIP-seq
MIRT1342578	hsa-miR-4768-3p	CLIP-seq
MIRT1342581	hsa-miR-485-5p	CLIP-seq
MIRT2101310	hsa-miR-539	CLIP-seq
MIRT1342588	hsa-miR-548b-3p	CLIP-seq
MIRT2101311	hsa-miR-595	CLIP-seq
MIRT1342597	hsa-miR-609	CLIP-seq
MIRT1342601	hsa-miR-762	CLIP-seq
MIRT2101312	hsa-miR-874	CLIP-seq
MIRT1342604	hsa-miR-940	CLIP-seq
MIRT2325706	hsa-miR-1273	CLIP-seq
MIRT1342489	hsa-miR-128	CLIP-seq
MIRT2325707	hsa-miR-217	CLIP-seq
MIRT1342503	hsa-miR-24	CLIP-seq
MIRT1342516	hsa-miR-320e	CLIP-seq
MIRT2325708	hsa-miR-338-3p	CLIP-seq
MIRT1342518	hsa-miR-33a	CLIP-seq
MIRT1342519	hsa-miR-33b	CLIP-seq
MIRT1342527	hsa-miR-3657	CLIP-seq
MIRT1342532	hsa-miR-3929	CLIP-seq
MIRT1342534	hsa-miR-3942-3p	CLIP-seq
MIRT1342537	hsa-miR-4257	CLIP-seq
MIRT1342539	hsa-miR-4284	CLIP-seq
MIRT1342541	hsa-miR-4419b	CLIP-seq
MIRT1342543	hsa-miR-4436b-3p	CLIP-seq
MIRT1342544	hsa-miR-4455	CLIP-seq
MIRT1342547	hsa-miR-4477b	CLIP-seq
MIRT1342548	hsa-miR-4478	CLIP-seq
MIRT2325709	hsa-miR-4486	CLIP-seq
MIRT1342550	hsa-miR-4492	CLIP-seq
MIRT1342551	hsa-miR-4498	CLIP-seq
MIRT1342554	hsa-miR-4505	CLIP-seq
MIRT2325710	hsa-miR-4520a-3p	CLIP-seq
MIRT1342557	hsa-miR-4649-3p	CLIP-seq
MIRT2325711	hsa-miR-4649-5p	CLIP-seq
MIRT1342562	hsa-miR-4669	CLIP-seq
MIRT1342568	hsa-miR-4722-5p	CLIP-seq
MIRT1342574	hsa-miR-4761-3p	CLIP-seq
MIRT1342578	hsa-miR-4768-3p	CLIP-seq
MIRT2325712	hsa-miR-4786-5p	CLIP-seq
MIRT1342579	hsa-miR-4795-5p	CLIP-seq
MIRT2325713	hsa-miR-4797-5p	CLIP-seq
MIRT1342581	hsa-miR-485-5p	CLIP-seq
MIRT2101310	hsa-miR-539	CLIP-seq
MIRT2325714	hsa-miR-545	CLIP-seq
MIRT1342597	hsa-miR-609	CLIP-seq
MIRT2325715	hsa-miR-622	CLIP-seq
MIRT2325716	hsa-miR-661	CLIP-seq
MIRT1342601	hsa-miR-762	CLIP-seq
MIRT1342604	hsa-miR-940	CLIP-seq
MIRT1342515	hsa-miR-3202	CLIP-seq
MIRT1342544	hsa-miR-4455	CLIP-seq
MIRT1342550	hsa-miR-4492	CLIP-seq
MIRT1342551	hsa-miR-4498	CLIP-seq
MIRT1342554	hsa-miR-4505	CLIP-seq
MIRT1342597	hsa-miR-609	CLIP-seq
MIRT1342601	hsa-miR-762	CLIP-seq
MIRT2325706	hsa-miR-1273	CLIP-seq
MIRT2325707	hsa-miR-217	CLIP-seq
MIRT2325709	hsa-miR-4486	CLIP-seq
MIRT2325711	hsa-miR-4649-5p	CLIP-seq
MIRT2325716	hsa-miR-661	CLIP-seq
MIRT2325706	hsa-miR-1273	CLIP-seq
MIRT2325707	hsa-miR-217	CLIP-seq
MIRT2621376	hsa-miR-4432	CLIP-seq
MIRT2325709	hsa-miR-4486	CLIP-seq
MIRT2621377	hsa-miR-451b	CLIP-seq
MIRT2621378	hsa-miR-4635	CLIP-seq
MIRT2325711	hsa-miR-4649-5p	CLIP-seq
MIRT1342559	hsa-miR-4662a-5p	CLIP-seq
MIRT2621379	hsa-miR-4696	CLIP-seq
MIRT2325716	hsa-miR-661	CLIP-seq
MIRT2621376	hsa-miR-4432	CLIP-seq
MIRT2621377	hsa-miR-451b	CLIP-seq
MIRT2621378	hsa-miR-4635	CLIP-seq
MIRT1342559	hsa-miR-4662a-5p	CLIP-seq
MIRT1342563	hsa-miR-4676-5p	CLIP-seq
MIRT2621379	hsa-miR-4696	CLIP-seq
MIRT1342594	hsa-miR-575	CLIP-seq

Gene ontology (GO) Show/Hide all (17)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005515	Function	Protein binding	IPI	32296183
GO:0005739	Component	Mitochondrion	HTP	34800366
GO:0005739	Component	Mitochondrion	IDA	30442778
GO:0005739	Component	Mitochondrion	IEA
GO:0005741	Component	Mitochondrial outer membrane	IDA	30570704
GO:0005741	Component	Mitochondrial outer membrane	IEA
GO:0005743	Component	Mitochondrial inner membrane	IBA
GO:0005743	Component	Mitochondrial inner membrane	IEA
GO:0006811	Process	Monoatomic ion transport	IEA
GO:0006865	Process	Amino acid transport	IEA
GO:0015075	Function	Monoatomic ion transmembrane transporter activity	IEA
GO:0016020	Component	Membrane	IEA
GO:0022857	Function	Transmembrane transporter activity	IBA
GO:0034220	Process	Monoatomic ion transmembrane transport	IEA
GO:0055085	Process	Transmembrane transport	IEA
GO:0140300	Process	Serine import into mitochondrion	IBA
GO:1990542	Process	Mitochondrial transmembrane transport	IDA	30442778

Other IDs

• MIM: 615570
• HGNC: 16086
• e!Ensembl: ENSG00000156398

Protein

• UniProt ID: Q96NB2
• Protein name: Sideroflexin-2
• Protein function: Mitochondrial amino-acid transporter that mediates transport of serine into mitochondria (PubMed:30442778). Involved in mitochondrial iron homeostasis by regulating heme biosynthesis (PubMed:30570704). {ECO:0000269|PubMed:30442778, ECO:0000269|P
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF03820	SFXNs	9 → 322	Sideroflexins	Family

• Tissue specificity: TISSUE SPECIFICITY: Widely expressed, highest levels in kidney, liver, and pancreas. {ECO:0000269|PubMed:12670026}.
• Sequence:

  MEADLSGFNIDAPRWDQRTFLGRVKHFLNITDPRTVFVSERELDWAKVMVEKSRMGVVPP
  GTQVEQLLYAKKLYDSAFHPDTGEKMNVIGRMSFQLPGGMIITGFMLQFYRTMPAVIFWQ
  WVNQSFNALVNYTNRNAASPTSVRQMALSYFTATTTAVATAVGMNMLTKKAPPLVGRWVP
  FAAVAAANCVNIPMMRQQELIKGICVKDRNENEIGHSRRAAAIGITQVVISRITMSAPGM
  ILLPVIMERLEKLHFMQKVKVLHAPLQVMLSGCFLIFMVPVACGLFPQKCELPVSYLEPK
  LQDTIKAKYGELEPYVYFNKGL

• Sequence length: 322

Related Genes

No strongly related genes found yet for SFXN2.

Diseases Linked via Similar Genes

No additional diseases found yet through genes similar to SFXN2.