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Gene Gene information from NCBI Gene database.
Entrez ID 29946
Gene name SERTA domain containing 3
Gene symbol SERTAD3
Synonyms (NCBI Gene)
RBT1
Chromosome 19
Chromosome location 19q13.2
Summary The protein encoded by this gene was identified in a yeast two-hybrid assay employing the second subunit of human replication protein A as bait. It is localized to the nucleus and its expression is significantly higher in cancer cell lines compared to nor
miRNA miRNA information provided by mirtarbase database.
465 Show/Hide all (465)
miRTarBase ID miRNA Experiments Reference
MIRT025961 hsa-miR-7-5p Sequencing 20371350
MIRT031339 hsa-miR-18a-5p Sequencing 20371350
MIRT050344 hsa-miR-25-3p CLASH 23622248
MIRT049827 hsa-miR-92a-3p CLASH 23622248
MIRT565752 hsa-miR-124-3p PAR-CLIP 20371350
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
9 Show/Hide all (9)
GO ID Ontology Definition Evidence Reference
GO:0005515 Function Protein binding IPI 10982866, 16189514, 19060904, 25416956, 31515488, 32296183
GO:0005634 Component Nucleus IBA
GO:0005634 Component Nucleus IDA 10982866, 16098148
GO:0005634 Component Nucleus IEA
GO:0006355 Process Regulation of DNA-templated transcription IDA 10982866
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
612125 17931 ENSG00000167565
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q9UJW9
Protein name SERTA domain-containing protein 3 (Replication protein-binding trans-activator) (RPA-binding trans-activator)
Protein function Antiviral interferon-stimulated protein that plays a role in innate immunity and in the suppression of viruses through different mechanisms (PubMed:33147462, PubMed:36594413). Plays a role in the late phase response of TLR-induced immune effecto
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF06031 SERTA 33 → 68 SERTA motif Motif
Sequence
MVGGLKRKHSDLEEEEERWEWSPAGLQSYQQALLRISLDKVQRSLGPRAPSLRRHVLIHN
TLQQLQAA
LRLAPAPALPPEPLFLGEEDFSLSATIGSILRELDTSMDGTEPPQNPVTPLG
LQNEVPPQPDPVFLEALSSRYLGDSGLDDFFLDIDTSAVEKEPARAPPEPPHNLFCAPGS
WEWNELDHIMEIILGS
Sequence length 196
Interactions View interactions