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Gene Gene information from NCBI Gene database.
Entrez ID 10169
Gene name Small EDRK-rich factor 2
Gene symbol SERF2
Synonyms (NCBI Gene)
4F5RELFAM2CH4F5RELHero7HsT17089
Chromosome 15
Chromosome location 15q15.3
miRNA miRNA information provided by mirtarbase database.
475 Show/Hide all (475)
miRTarBase ID miRNA Experiments Reference
MIRT051519 hsa-let-7e-5p CLASH 23622248
MIRT624959 hsa-miR-6890-3p HITS-CLIP 23824327
MIRT624958 hsa-miR-6736-3p HITS-CLIP 23824327
MIRT624957 hsa-miR-1304-3p HITS-CLIP 23824327
MIRT624956 hsa-miR-6787-3p HITS-CLIP 23824327
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
3
GO ID Ontology Definition Evidence Reference
GO:0005634 Component Nucleus ISS
GO:0005829 Component Cytosol ISS
GO:0031648 Process Protein destabilization IMP 20723760
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
605054 10757 ENSG00000140264
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
P84101
Protein name Small EDRK-rich factor 2 (Gastric cancer-related protein VRG107) (Protein 4F5-related) (4F5rel) (h4F5rel)
Protein function Positive regulator of amyloid protein aggregation and proteotoxicity (PubMed:20723760). Induces conformational changes in amyloid proteins, such as HTT, driving them into compact formations preceding the formation of aggregates (PubMed:20723760)
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF04419 4F5 1 → 38 4F5 protein related disordered region Disordered
Sequence
Sequence length 59
Interactions View interactions