SCYL3 (SCY1 like pseudokinase 3)

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Gene miRNA Gene ontology Other IDs Protein Related genes Diseases linked via similar genes

Gene

• Entrez ID: 57147
• Gene name: SCY1 like pseudokinase 3
• Gene symbol: SCYL3
• Synonyms (NCBI Gene): PACE-1, PACE1
• Chromosome: 1
• Chromosome location: 1q24.2
• Summary: This gene encodes a protein with a kinase domain and four HEAT repeats. The encoded protein interacts with the C-terminal domain of ezrin, an ERM protein, and may play a role in cell adhesion and migration. Alternative splicing results in multiple transcr

miRNA Show/Hide all (288)

miRTarBase ID	miRNA	Experiments	Reference
MIRT045388	hsa-miR-149-5p	CLASH	23622248
MIRT653998	hsa-miR-548at-5p	HITS-CLIP	23824327
MIRT653997	hsa-miR-561-3p	HITS-CLIP	23824327
MIRT619336	hsa-miR-500a-5p	HITS-CLIP	23824327
MIRT619335	hsa-miR-501-5p	HITS-CLIP	23824327
MIRT653996	hsa-miR-5009-3p	HITS-CLIP	23824327
MIRT619334	hsa-miR-3685	HITS-CLIP	23824327
MIRT619333	hsa-miR-384	HITS-CLIP	23824327
MIRT625940	hsa-miR-135a-5p	HITS-CLIP	23824327
MIRT625939	hsa-miR-135b-5p	HITS-CLIP	23824327
MIRT625938	hsa-miR-130b-5p	HITS-CLIP	23824327
MIRT625937	hsa-miR-3622b-5p	HITS-CLIP	23824327
MIRT625936	hsa-miR-3119	HITS-CLIP	23824327
MIRT625935	hsa-miR-4753-3p	HITS-CLIP	23824327
MIRT625934	hsa-miR-7156-3p	HITS-CLIP	23824327
MIRT625933	hsa-miR-1301-3p	HITS-CLIP	23824327
MIRT625932	hsa-miR-5047	HITS-CLIP	23824327
MIRT625931	hsa-miR-6809-3p	HITS-CLIP	23824327
MIRT625930	hsa-miR-6516-5p	HITS-CLIP	23824327
MIRT619336	hsa-miR-500a-5p	HITS-CLIP	23824327
MIRT619335	hsa-miR-501-5p	HITS-CLIP	23824327
MIRT619334	hsa-miR-3685	HITS-CLIP	23824327
MIRT619333	hsa-miR-384	HITS-CLIP	23824327
MIRT625933	hsa-miR-1301-3p	HITS-CLIP	27418678
MIRT625933	hsa-miR-1301-3p	HITS-CLIP	27418678
MIRT625933	hsa-miR-1301-3p	HITS-CLIP	27418678
MIRT625933	hsa-miR-1301-3p	HITS-CLIP	27418678
MIRT625933	hsa-miR-1301-3p	HITS-CLIP	27418678
MIRT625933	hsa-miR-1301-3p	HITS-CLIP	27418678
MIRT625938	hsa-miR-130b-5p	HITS-CLIP	27418678
MIRT625938	hsa-miR-130b-5p	HITS-CLIP	27418678
MIRT625938	hsa-miR-130b-5p	HITS-CLIP	27418678
MIRT625938	hsa-miR-130b-5p	HITS-CLIP	27418678
MIRT625938	hsa-miR-130b-5p	HITS-CLIP	27418678
MIRT625938	hsa-miR-130b-5p	HITS-CLIP	27418678
MIRT625940	hsa-miR-135a-5p	HITS-CLIP	27418678
MIRT625940	hsa-miR-135a-5p	HITS-CLIP	27418678
MIRT625940	hsa-miR-135a-5p	HITS-CLIP	27418678
MIRT625940	hsa-miR-135a-5p	HITS-CLIP	27418678
MIRT625940	hsa-miR-135a-5p	HITS-CLIP	27418678
MIRT625939	hsa-miR-135b-5p	HITS-CLIP	27418678
MIRT625939	hsa-miR-135b-5p	HITS-CLIP	27418678
MIRT625939	hsa-miR-135b-5p	HITS-CLIP	27418678
MIRT625939	hsa-miR-135b-5p	HITS-CLIP	27418678
MIRT625939	hsa-miR-135b-5p	HITS-CLIP	27418678
MIRT625936	hsa-miR-3119	HITS-CLIP	27418678
MIRT625936	hsa-miR-3119	HITS-CLIP	27418678
MIRT625936	hsa-miR-3119	HITS-CLIP	27418678
MIRT625936	hsa-miR-3119	HITS-CLIP	27418678
MIRT625936	hsa-miR-3119	HITS-CLIP	27418678
MIRT625935	hsa-miR-4753-3p	HITS-CLIP	27418678
MIRT625935	hsa-miR-4753-3p	HITS-CLIP	27418678
MIRT625935	hsa-miR-4753-3p	HITS-CLIP	27418678
MIRT625935	hsa-miR-4753-3p	HITS-CLIP	27418678
MIRT625935	hsa-miR-4753-3p	HITS-CLIP	27418678
MIRT625935	hsa-miR-4753-3p	HITS-CLIP	27418678
MIRT625932	hsa-miR-5047	HITS-CLIP	27418678
MIRT625932	hsa-miR-5047	HITS-CLIP	27418678
MIRT625932	hsa-miR-5047	HITS-CLIP	27418678
MIRT625932	hsa-miR-5047	HITS-CLIP	27418678
MIRT625932	hsa-miR-5047	HITS-CLIP	27418678
MIRT625932	hsa-miR-5047	HITS-CLIP	27418678
MIRT625930	hsa-miR-6516-5p	HITS-CLIP	27418678
MIRT625930	hsa-miR-6516-5p	HITS-CLIP	27418678
MIRT625930	hsa-miR-6516-5p	HITS-CLIP	27418678
MIRT625930	hsa-miR-6516-5p	HITS-CLIP	27418678
MIRT625930	hsa-miR-6516-5p	HITS-CLIP	27418678
MIRT625931	hsa-miR-6809-3p	HITS-CLIP	27418678
MIRT625931	hsa-miR-6809-3p	HITS-CLIP	27418678
MIRT625931	hsa-miR-6809-3p	HITS-CLIP	27418678
MIRT625931	hsa-miR-6809-3p	HITS-CLIP	27418678
MIRT625931	hsa-miR-6809-3p	HITS-CLIP	27418678
MIRT625931	hsa-miR-6809-3p	HITS-CLIP	27418678
MIRT625934	hsa-miR-7156-3p	HITS-CLIP	27418678
MIRT625934	hsa-miR-7156-3p	HITS-CLIP	27418678
MIRT625934	hsa-miR-7156-3p	HITS-CLIP	27418678
MIRT625934	hsa-miR-7156-3p	HITS-CLIP	27418678
MIRT625934	hsa-miR-7156-3p	HITS-CLIP	27418678
MIRT625934	hsa-miR-7156-3p	HITS-CLIP	27418678
MIRT625933	hsa-miR-1301-3p	HITS-CLIP	28735896
MIRT625938	hsa-miR-130b-5p	HITS-CLIP	28735896
MIRT625940	hsa-miR-135a-5p	HITS-CLIP	28735896
MIRT625939	hsa-miR-135b-5p	HITS-CLIP	28735896
MIRT625936	hsa-miR-3119	HITS-CLIP	28735896
MIRT625935	hsa-miR-4753-3p	HITS-CLIP	28735896
MIRT625932	hsa-miR-5047	HITS-CLIP	28735896
MIRT625930	hsa-miR-6516-5p	HITS-CLIP	28735896
MIRT625931	hsa-miR-6809-3p	HITS-CLIP	28735896
MIRT625934	hsa-miR-7156-3p	HITS-CLIP	28735896
MIRT653998	hsa-miR-548at-5p	HITS-CLIP	23824327
MIRT653997	hsa-miR-561-3p	HITS-CLIP	23824327
MIRT619336	hsa-miR-500a-5p	HITS-CLIP	23824327
MIRT619335	hsa-miR-501-5p	HITS-CLIP	23824327
MIRT653996	hsa-miR-5009-3p	HITS-CLIP	23824327
MIRT619334	hsa-miR-3685	HITS-CLIP	23824327
MIRT619333	hsa-miR-384	HITS-CLIP	23824327
MIRT625940	hsa-miR-135a-5p	HITS-CLIP	23824327
MIRT625939	hsa-miR-135b-5p	HITS-CLIP	23824327
MIRT625938	hsa-miR-130b-5p	HITS-CLIP	23824327
MIRT625937	hsa-miR-3622b-5p	HITS-CLIP	23824327
MIRT625936	hsa-miR-3119	HITS-CLIP	23824327
MIRT625935	hsa-miR-4753-3p	HITS-CLIP	23824327
MIRT625934	hsa-miR-7156-3p	HITS-CLIP	23824327
MIRT625933	hsa-miR-1301-3p	HITS-CLIP	23824327
MIRT625932	hsa-miR-5047	HITS-CLIP	23824327
MIRT625931	hsa-miR-6809-3p	HITS-CLIP	23824327
MIRT625930	hsa-miR-6516-5p	HITS-CLIP	23824327
MIRT619336	hsa-miR-500a-5p	HITS-CLIP	23824327
MIRT619335	hsa-miR-501-5p	HITS-CLIP	23824327
MIRT619334	hsa-miR-3685	HITS-CLIP	23824327
MIRT619333	hsa-miR-384	HITS-CLIP	23824327
MIRT1331029	hsa-let-7a	CLIP-seq
MIRT1331030	hsa-let-7b	CLIP-seq
MIRT1331031	hsa-let-7c	CLIP-seq
MIRT1331032	hsa-let-7d	CLIP-seq
MIRT1331033	hsa-let-7e	CLIP-seq
MIRT1331034	hsa-let-7f	CLIP-seq
MIRT1331035	hsa-let-7g	CLIP-seq
MIRT1331036	hsa-let-7i	CLIP-seq
MIRT1331037	hsa-miR-1243	CLIP-seq
MIRT1331038	hsa-miR-1261	CLIP-seq
MIRT1331039	hsa-miR-1271	CLIP-seq
MIRT1331040	hsa-miR-1303	CLIP-seq
MIRT1331041	hsa-miR-1304	CLIP-seq
MIRT1331042	hsa-miR-1343	CLIP-seq
MIRT1331043	hsa-miR-202	CLIP-seq
MIRT1331044	hsa-miR-2355-3p	CLIP-seq
MIRT1331045	hsa-miR-3123	CLIP-seq
MIRT1331046	hsa-miR-3140-3p	CLIP-seq
MIRT1331047	hsa-miR-3148	CLIP-seq
MIRT1331048	hsa-miR-3153	CLIP-seq
MIRT1331049	hsa-miR-3170	CLIP-seq
MIRT1331050	hsa-miR-3655	CLIP-seq
MIRT1331051	hsa-miR-3670	CLIP-seq
MIRT1331052	hsa-miR-3690	CLIP-seq
MIRT1331053	hsa-miR-376a	CLIP-seq
MIRT1331054	hsa-miR-376b	CLIP-seq
MIRT1331055	hsa-miR-3925-5p	CLIP-seq
MIRT1331056	hsa-miR-4254	CLIP-seq
MIRT1331057	hsa-miR-4260	CLIP-seq
MIRT1331058	hsa-miR-4279	CLIP-seq
MIRT1331059	hsa-miR-4458	CLIP-seq
MIRT1331060	hsa-miR-4463	CLIP-seq
MIRT1331061	hsa-miR-4494	CLIP-seq
MIRT1331062	hsa-miR-4500	CLIP-seq
MIRT1331063	hsa-miR-4646-3p	CLIP-seq
MIRT1331064	hsa-miR-4668-5p	CLIP-seq
MIRT1331065	hsa-miR-4678	CLIP-seq
MIRT1331066	hsa-miR-4715-5p	CLIP-seq
MIRT1331067	hsa-miR-4773	CLIP-seq
MIRT1331068	hsa-miR-489	CLIP-seq
MIRT1331069	hsa-miR-514	CLIP-seq
MIRT1331070	hsa-miR-514b-3p	CLIP-seq
MIRT1331071	hsa-miR-556-5p	CLIP-seq
MIRT1331072	hsa-miR-578	CLIP-seq
MIRT1331073	hsa-miR-596	CLIP-seq
MIRT1331074	hsa-miR-676	CLIP-seq
MIRT1331075	hsa-miR-875-3p	CLIP-seq
MIRT1331076	hsa-miR-96	CLIP-seq
MIRT1331077	hsa-miR-98	CLIP-seq
MIRT1331078	hsa-miR-128	CLIP-seq
MIRT1331042	hsa-miR-1343	CLIP-seq
MIRT1331079	hsa-miR-1915	CLIP-seq
MIRT1331080	hsa-miR-22	CLIP-seq
MIRT1331081	hsa-miR-27a	CLIP-seq
MIRT1331082	hsa-miR-27b	CLIP-seq
MIRT1331083	hsa-miR-30a	CLIP-seq
MIRT1331084	hsa-miR-30b	CLIP-seq
MIRT1331085	hsa-miR-30c	CLIP-seq
MIRT1331086	hsa-miR-30d	CLIP-seq
MIRT1331087	hsa-miR-30e	CLIP-seq
MIRT1331048	hsa-miR-3153	CLIP-seq
MIRT1331088	hsa-miR-3158-3p	CLIP-seq
MIRT1331089	hsa-miR-320e	CLIP-seq
MIRT1331090	hsa-miR-3607-3p	CLIP-seq
MIRT1331091	hsa-miR-3647-3p	CLIP-seq
MIRT1331051	hsa-miR-3670	CLIP-seq
MIRT1331092	hsa-miR-4330	CLIP-seq
MIRT1331093	hsa-miR-4496	CLIP-seq
MIRT1331094	hsa-miR-4521	CLIP-seq
MIRT1331095	hsa-miR-4662a-5p	CLIP-seq
MIRT1331064	hsa-miR-4668-5p	CLIP-seq
MIRT1331096	hsa-miR-4676-5p	CLIP-seq
MIRT1331097	hsa-miR-4685-5p	CLIP-seq
MIRT1331098	hsa-miR-510	CLIP-seq
MIRT1331099	hsa-miR-512-5p	CLIP-seq
MIRT1331071	hsa-miR-556-5p	CLIP-seq
MIRT1331100	hsa-miR-575	CLIP-seq
MIRT1331101	hsa-miR-622	CLIP-seq
MIRT1331039	hsa-miR-1271	CLIP-seq
MIRT1331040	hsa-miR-1303	CLIP-seq
MIRT1331042	hsa-miR-1343	CLIP-seq
MIRT1331045	hsa-miR-3123	CLIP-seq
MIRT1331048	hsa-miR-3153	CLIP-seq
MIRT1331051	hsa-miR-3670	CLIP-seq
MIRT2097902	hsa-miR-3682-5p	CLIP-seq
MIRT1331055	hsa-miR-3925-5p	CLIP-seq
MIRT1331064	hsa-miR-4668-5p	CLIP-seq
MIRT1331066	hsa-miR-4715-5p	CLIP-seq
MIRT1331067	hsa-miR-4773	CLIP-seq
MIRT1331068	hsa-miR-489	CLIP-seq
MIRT1331069	hsa-miR-514	CLIP-seq
MIRT1331070	hsa-miR-514b-3p	CLIP-seq
MIRT1331071	hsa-miR-556-5p	CLIP-seq
MIRT1331101	hsa-miR-622	CLIP-seq
MIRT1331076	hsa-miR-96	CLIP-seq
MIRT2322406	hsa-miR-105	CLIP-seq
MIRT2322407	hsa-miR-1236	CLIP-seq
MIRT1331037	hsa-miR-1243	CLIP-seq
MIRT1331038	hsa-miR-1261	CLIP-seq
MIRT1331078	hsa-miR-128	CLIP-seq
MIRT1331040	hsa-miR-1303	CLIP-seq
MIRT2322408	hsa-miR-132	CLIP-seq
MIRT1331042	hsa-miR-1343	CLIP-seq
MIRT2322409	hsa-miR-193a-3p	CLIP-seq
MIRT2322410	hsa-miR-193b	CLIP-seq
MIRT2322411	hsa-miR-1972	CLIP-seq
MIRT2322412	hsa-miR-212	CLIP-seq
MIRT2322413	hsa-miR-219-2-3p	CLIP-seq
MIRT1331081	hsa-miR-27a	CLIP-seq
MIRT1331082	hsa-miR-27b	CLIP-seq
MIRT1331045	hsa-miR-3123	CLIP-seq
MIRT2322414	hsa-miR-3133	CLIP-seq
MIRT2322415	hsa-miR-3135	CLIP-seq
MIRT1331048	hsa-miR-3153	CLIP-seq
MIRT2322416	hsa-miR-3176	CLIP-seq
MIRT2322417	hsa-miR-3180-5p	CLIP-seq
MIRT2322418	hsa-miR-3190	CLIP-seq
MIRT1331051	hsa-miR-3670	CLIP-seq
MIRT2097902	hsa-miR-3682-5p	CLIP-seq
MIRT1331052	hsa-miR-3690	CLIP-seq
MIRT1331053	hsa-miR-376a	CLIP-seq
MIRT1331054	hsa-miR-376b	CLIP-seq
MIRT2322419	hsa-miR-3922-3p	CLIP-seq
MIRT1331055	hsa-miR-3925-5p	CLIP-seq
MIRT1331056	hsa-miR-4254	CLIP-seq
MIRT2322420	hsa-miR-4261	CLIP-seq
MIRT2322421	hsa-miR-4264	CLIP-seq
MIRT1331058	hsa-miR-4279	CLIP-seq
MIRT1331060	hsa-miR-4463	CLIP-seq
MIRT2322422	hsa-miR-4491	CLIP-seq
MIRT1331061	hsa-miR-4494	CLIP-seq
MIRT2322423	hsa-miR-4657	CLIP-seq
MIRT2322424	hsa-miR-4666-5p	CLIP-seq
MIRT1331064	hsa-miR-4668-5p	CLIP-seq
MIRT2322425	hsa-miR-4690-5p	CLIP-seq
MIRT2322426	hsa-miR-4691-5p	CLIP-seq
MIRT2322427	hsa-miR-4699-3p	CLIP-seq
MIRT2322428	hsa-miR-4704-3p	CLIP-seq
MIRT1331066	hsa-miR-4715-5p	CLIP-seq
MIRT2322429	hsa-miR-4717-5p	CLIP-seq
MIRT2322430	hsa-miR-4738-3p	CLIP-seq
MIRT2322431	hsa-miR-4757-5p	CLIP-seq
MIRT1331067	hsa-miR-4773	CLIP-seq
MIRT1331068	hsa-miR-489	CLIP-seq
MIRT1331098	hsa-miR-510	CLIP-seq
MIRT1331099	hsa-miR-512-5p	CLIP-seq
MIRT1331069	hsa-miR-514	CLIP-seq
MIRT1331070	hsa-miR-514b-3p	CLIP-seq
MIRT2322432	hsa-miR-520a-5p	CLIP-seq
MIRT2322433	hsa-miR-525-5p	CLIP-seq
MIRT2322434	hsa-miR-548b-3p	CLIP-seq
MIRT1331071	hsa-miR-556-5p	CLIP-seq
MIRT2322435	hsa-miR-561	CLIP-seq
MIRT1331101	hsa-miR-622	CLIP-seq
MIRT2322436	hsa-miR-873	CLIP-seq
MIRT1331075	hsa-miR-875-3p	CLIP-seq
MIRT2322408	hsa-miR-132	CLIP-seq
MIRT2322412	hsa-miR-212	CLIP-seq
MIRT2322415	hsa-miR-3135	CLIP-seq
MIRT2322436	hsa-miR-873	CLIP-seq
MIRT2458995	hsa-miR-2682	CLIP-seq
MIRT2458996	hsa-miR-34c-3p	CLIP-seq
MIRT2458997	hsa-miR-449c	CLIP-seq
MIRT2458998	hsa-miR-629	CLIP-seq
MIRT2458999	hsa-miR-940	CLIP-seq
MIRT2322413	hsa-miR-219-2-3p	CLIP-seq
MIRT1331044	hsa-miR-2355-3p	CLIP-seq
MIRT1331047	hsa-miR-3148	CLIP-seq
MIRT2322417	hsa-miR-3180-5p	CLIP-seq
MIRT2097902	hsa-miR-3682-5p	CLIP-seq
MIRT1331052	hsa-miR-3690	CLIP-seq
MIRT1331056	hsa-miR-4254	CLIP-seq
MIRT2618675	hsa-miR-4452	CLIP-seq
MIRT2322432	hsa-miR-520a-5p	CLIP-seq
MIRT2322433	hsa-miR-525-5p	CLIP-seq
MIRT1331074	hsa-miR-676	CLIP-seq
MIRT1331075	hsa-miR-875-3p	CLIP-seq

Gene ontology (GO) Show/Hide all (19)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000139	Component	Golgi membrane	IEA
GO:0005515	Function	Protein binding	IPI	12651155, 25416956, 31515488, 32296183, 32707033, 32814053, 34524948
GO:0005524	Function	ATP binding	IEA
GO:0005737	Component	Cytoplasm	IDA	12651155
GO:0005737	Component	Cytoplasm	IEA
GO:0005783	Component	Endoplasmic reticulum	IDA
GO:0005794	Component	Golgi apparatus	IDA	12651155
GO:0005794	Component	Golgi apparatus	IEA
GO:0005829	Component	Cytosol	IDA
GO:0006954	Process	Inflammatory response	IEA
GO:0008104	Process	Intracellular protein localization	IEA
GO:0016301	Function	Kinase activity	IDA	12651155
GO:0016477	Process	Cell migration	NAS	12651155
GO:0021522	Process	Spinal cord motor neuron differentiation	IEA
GO:0030027	Component	Lamellipodium	IDA	12651155
GO:0030027	Component	Lamellipodium	IEA
GO:0042802	Function	Identical protein binding	IEA
GO:0042995	Component	Cell projection	IEA
GO:0048666	Process	Neuron development	IEA

Other IDs

• MIM: 608192
• HGNC: 19285
• e!Ensembl: ENSG00000000457

Protein

• UniProt ID: Q8IZE3
• Protein name: Protein-associating with the carboxyl-terminal domain of ezrin (Ezrin-binding protein PACE-1) (SCY1-like protein 3)
• Protein function: May play a role in regulating cell adhesion/migration complexes in migrating cells.
• Tissue specificity: TISSUE SPECIFICITY: Ubiquitously expressed. {ECO:0000269|PubMed:12651155}.
• Sequence:

  MGSENSALKSYTLREPPFTLPSGLAVYPAVLQDGKFASVFVYKRENEDKVNKAAKHLKTL
  RHPCLLRFLSCTVEADGIHLVTERVQPLEVALETLSSAEVCAGIYDILLALIFLHDRGHL
  THNNVCLSSVFVSEDGHWKLGGMETVCKVSQATPEFLRSIQSIRDPASIPPEEMSPEFTT
  LPECHGHARDAFSFGTLVESLLTILNEQVSADVLSSFQQTLHSTLLNPIPKCRPALCTLL
  SHDFFRNDFLEVVNFLKSLTLKSEEEKTEFFKFLLDRVSCLSEELIASRLVPLLLNQLVF
  AEPVAVKSFLPYLLGPKKDHAQGETPCLLSPALFQSRVIPVLLQLFEVHEEHVRMVLLSH
  IEAYVEHFTQEQLKKVILPQVLLGLRDTSDSIVAITLHSLAVLVSLLGPEVVVGGERTKI
  FKRTAPSFTKNTDLSLEDSPMCVVCSHHSQISPILENPFSSIFPKCFFSGSTPINSKKHI
  QRDYYNTLLQTGDPFSQPIKFPINGLSDVKNTSEDSENFPSSSKKSEEWPDWSEPEEPEN
  QTVNIQIWPREPCDDVKSQCTTLDVEESSWDDCEPSSLDTKVNPGGGITATKPVTSGEQK
  PIPALLSLTEESMPWKSSLPQKISLVQRGDDADQIEPPKVSSQERPLKVPSELGLGEEFT
  IQVKKKPVKDPEMDWFADMIPEIKPSAAFLILPELRTEMVPKKDDVSPVMQFSSKFAAAE
  ITEGEAEGWEEEGELNWEDNNW

• Sequence length: 742

Related Genes

No strongly related genes found yet for SCYL3.

Diseases Linked via Similar Genes

No additional diseases found yet through genes similar to SCYL3.