Log in to bookmark this gene

Bookmark This Gene

Gene Gene information from NCBI Gene database.
Entrez ID 57402
Gene name S100 calcium binding protein A14
Gene symbol S100A14
Synonyms (NCBI Gene)
BCMP84S100A15
Chromosome 1
Chromosome location 1q21.3
Summary This gene encodes a member of the S100 protein family which contains an EF-hand motif and binds calcium. The gene is located in a cluster of S100 genes on chromosome 1. Levels of the encoded protein have been found to be lower in cancerous tissue and asso
miRNA miRNA information provided by mirtarbase database.
212 Show/Hide all (212)
miRTarBase ID miRNA Experiments Reference
MIRT016384 hsa-miR-193b-3p Proteomics 21512034
MIRT051084 hsa-miR-16-5p CLASH 23622248
MIRT1323906 hsa-miR-1207-3p CLIP-seq
MIRT1323907 hsa-miR-1252 CLIP-seq
MIRT1323908 hsa-miR-1324 CLIP-seq
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
22 Show/Hide all (22)
GO ID Ontology Definition Evidence Reference
GO:0005509 Function Calcium ion binding IBA
GO:0005509 Function Calcium ion binding NAS 16682778
GO:0005515 Function Protein binding IPI 16189514, 25416956, 32296183
GO:0005615 Component Extracellular space IBA
GO:0005737 Component Cytoplasm IEA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
607986 18901 ENSG00000189334
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q9HCY8
Protein name Protein S100-A14 (S100 calcium-binding protein A14) (S114)
Protein function Modulates P53/TP53 protein levels, and thereby plays a role in the regulation of cell survival and apoptosis. Depending on the context, it can promote cell proliferation or apoptosis. Plays a role in the regulation of cell migration by modulatin
PDB 2M0R
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF01023 S_100 18 → 59 S-100/ICaBP type calcium binding domain Domain
Tissue specificity TISSUE SPECIFICITY: Expressed at highest levels in colon and at moderate levels in thymus, kidney, liver, small intestine, and lung. Low expression in heart and no expression is seen in brain, skeletal muscle, spleen, placenta and peripheral blood leukocy
Sequence
MGQCRSANAEDAQEFSDVERAIETLIKNFHQYSVEGGKETLTPSELRDLVTQQLPHLMPS
NCGLEEKIANLGSCNDSKLEFRSFWELIGEAAKSVKLERPVRGH
Sequence length 104
Interactions View interactions