S100A14 (S100 calcium binding protein A14)
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Gene
Gene information from NCBI Gene database.
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| Entrez ID | 57402 |
| Gene name | S100 calcium binding protein A14 |
| Gene symbol | S100A14 |
| Synonyms (NCBI Gene) |
BCMP84S100A15
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| Chromosome | 1 |
| Chromosome location | 1q21.3 |
| Summary | This gene encodes a member of the S100 protein family which contains an EF-hand motif and binds calcium. The gene is located in a cluster of S100 genes on chromosome 1. Levels of the encoded protein have been found to be lower in cancerous tissue and asso |
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miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
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Other IDs
Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
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Protein
Protein information from UniProt database.
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UniProt ID
Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
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Q9HCY8 | ||||||||||
| Protein name | Protein S100-A14 (S100 calcium-binding protein A14) (S114) | ||||||||||
| Protein function | Modulates P53/TP53 protein levels, and thereby plays a role in the regulation of cell survival and apoptosis. Depending on the context, it can promote cell proliferation or apoptosis. Plays a role in the regulation of cell migration by modulatin | ||||||||||
| PDB | 2M0R | ||||||||||
| Family and domains |
Pfam
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| Tissue specificity | TISSUE SPECIFICITY: Expressed at highest levels in colon and at moderate levels in thymus, kidney, liver, small intestine, and lung. Low expression in heart and no expression is seen in brain, skeletal muscle, spleen, placenta and peripheral blood leukocy | ||||||||||
| Sequence |
MGQCRSANAEDAQEFSDVERAIETLIKNFHQYSVEGGKETLTPSELRDLVTQQLPHLMPS |
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| Sequence length | 104 | ||||||||||
| Interactions | View interactions | ||||||||||
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Related Genes
Genes most often co-reported with S100A14 across shared curated disease and pathway associations.
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Diseases Linked via Similar Genes
Diseases curated for genes most similar to S100A14 (see Related Genes above), that are NOT already directly curated for S100A14 itself -- a lead worth checking, not a confirmed association.
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