RUSC1 (RUN and SH3 domain containing 1)

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Gene miRNA Gene ontology Other IDs Protein Diseases linked via similar genes

Gene

• Entrez ID: 23623
• Gene name: RUN and SH3 domain containing 1
• Gene symbol: RUSC1
• Synonyms (NCBI Gene): NESCA
• Chromosome: 1
• Chromosome location: 1q22

miRNA Show/Hide all (367)

miRTarBase ID	miRNA	Experiments	Reference
MIRT016602	hsa-miR-193b-3p	Microarray	20304954
MIRT025953	hsa-miR-7-5p	Microarray	19073608
MIRT039308	hsa-miR-425-5p	CLASH	23622248
MIRT1323051	hsa-miR-1193	CLIP-seq
MIRT1323052	hsa-miR-122	CLIP-seq
MIRT1323053	hsa-miR-1237	CLIP-seq
MIRT1323054	hsa-miR-1248	CLIP-seq
MIRT1323055	hsa-miR-1275	CLIP-seq
MIRT1323056	hsa-miR-1827	CLIP-seq
MIRT1323057	hsa-miR-1911	CLIP-seq
MIRT1323058	hsa-miR-1915	CLIP-seq
MIRT1323059	hsa-miR-193a-3p	CLIP-seq
MIRT1323060	hsa-miR-193b	CLIP-seq
MIRT1323061	hsa-miR-198	CLIP-seq
MIRT1323062	hsa-miR-2110	CLIP-seq
MIRT1323063	hsa-miR-2467-3p	CLIP-seq
MIRT1323064	hsa-miR-3065-3p	CLIP-seq
MIRT1323065	hsa-miR-3120-3p	CLIP-seq
MIRT1323066	hsa-miR-3174	CLIP-seq
MIRT1323067	hsa-miR-3187-3p	CLIP-seq
MIRT1323068	hsa-miR-3192	CLIP-seq
MIRT1323069	hsa-miR-323-3p	CLIP-seq
MIRT1323070	hsa-miR-3678-3p	CLIP-seq
MIRT1323071	hsa-miR-3689a-3p	CLIP-seq
MIRT1323072	hsa-miR-3689c	CLIP-seq
MIRT1323073	hsa-miR-3692	CLIP-seq
MIRT1323074	hsa-miR-4271	CLIP-seq
MIRT1323075	hsa-miR-4291	CLIP-seq
MIRT1323076	hsa-miR-4314	CLIP-seq
MIRT1323077	hsa-miR-4420	CLIP-seq
MIRT1323078	hsa-miR-4428	CLIP-seq
MIRT1323079	hsa-miR-4436b-5p	CLIP-seq
MIRT1323080	hsa-miR-4438	CLIP-seq
MIRT1323081	hsa-miR-4476	CLIP-seq
MIRT1323082	hsa-miR-4481	CLIP-seq
MIRT1323083	hsa-miR-4488	CLIP-seq
MIRT1323084	hsa-miR-450b-5p	CLIP-seq
MIRT1323085	hsa-miR-4529-5p	CLIP-seq
MIRT1323086	hsa-miR-4533	CLIP-seq
MIRT1323087	hsa-miR-4534	CLIP-seq
MIRT1323088	hsa-miR-455-3p	CLIP-seq
MIRT1323089	hsa-miR-4645-5p	CLIP-seq
MIRT1323090	hsa-miR-4646-5p	CLIP-seq
MIRT1323091	hsa-miR-4649-3p	CLIP-seq
MIRT1323092	hsa-miR-4656	CLIP-seq
MIRT1323093	hsa-miR-4665-5p	CLIP-seq
MIRT1323094	hsa-miR-4668-5p	CLIP-seq
MIRT1323095	hsa-miR-4673	CLIP-seq
MIRT1323096	hsa-miR-4694-5p	CLIP-seq
MIRT1323097	hsa-miR-4697-5p	CLIP-seq
MIRT1323098	hsa-miR-4699-5p	CLIP-seq
MIRT1323099	hsa-miR-4725-3p	CLIP-seq
MIRT1323100	hsa-miR-4726-3p	CLIP-seq
MIRT1323101	hsa-miR-4728-5p	CLIP-seq
MIRT1323102	hsa-miR-4742-5p	CLIP-seq
MIRT1323103	hsa-miR-4745-5p	CLIP-seq
MIRT1323104	hsa-miR-4765	CLIP-seq
MIRT1323105	hsa-miR-491-5p	CLIP-seq
MIRT1323106	hsa-miR-507	CLIP-seq
MIRT1323107	hsa-miR-5095	CLIP-seq
MIRT1323108	hsa-miR-557	CLIP-seq
MIRT1323109	hsa-miR-598	CLIP-seq
MIRT1323110	hsa-miR-645	CLIP-seq
MIRT1323111	hsa-miR-891b	CLIP-seq
MIRT1323112	hsa-miR-892b	CLIP-seq
MIRT1323052	hsa-miR-122	CLIP-seq
MIRT1323053	hsa-miR-1237	CLIP-seq
MIRT1323113	hsa-miR-1246	CLIP-seq
MIRT1323054	hsa-miR-1248	CLIP-seq
MIRT1323114	hsa-miR-1252	CLIP-seq
MIRT1323115	hsa-miR-1255a	CLIP-seq
MIRT1323116	hsa-miR-1255b	CLIP-seq
MIRT1323117	hsa-miR-125a-3p	CLIP-seq
MIRT1323055	hsa-miR-1275	CLIP-seq
MIRT1323118	hsa-miR-1302	CLIP-seq
MIRT1323119	hsa-miR-140-3p	CLIP-seq
MIRT1323120	hsa-miR-181a	CLIP-seq
MIRT1323121	hsa-miR-181b	CLIP-seq
MIRT1323122	hsa-miR-181c	CLIP-seq
MIRT1323123	hsa-miR-181d	CLIP-seq
MIRT1323056	hsa-miR-1827	CLIP-seq
MIRT1323057	hsa-miR-1911	CLIP-seq
MIRT1323058	hsa-miR-1915	CLIP-seq
MIRT1323059	hsa-miR-193a-3p	CLIP-seq
MIRT1323060	hsa-miR-193b	CLIP-seq
MIRT1323124	hsa-miR-197	CLIP-seq
MIRT1323061	hsa-miR-198	CLIP-seq
MIRT1323125	hsa-miR-204	CLIP-seq
MIRT1323126	hsa-miR-211	CLIP-seq
MIRT1323127	hsa-miR-2278	CLIP-seq
MIRT1323064	hsa-miR-3065-3p	CLIP-seq
MIRT1323065	hsa-miR-3120-3p	CLIP-seq
MIRT1323128	hsa-miR-3122	CLIP-seq
MIRT1323129	hsa-miR-3148	CLIP-seq
MIRT1323130	hsa-miR-3173-3p	CLIP-seq
MIRT1323066	hsa-miR-3174	CLIP-seq
MIRT1323131	hsa-miR-3185	CLIP-seq
MIRT1323067	hsa-miR-3187-3p	CLIP-seq
MIRT1323069	hsa-miR-323-3p	CLIP-seq
MIRT1323132	hsa-miR-3617	CLIP-seq
MIRT1323070	hsa-miR-3678-3p	CLIP-seq
MIRT1323071	hsa-miR-3689a-3p	CLIP-seq
MIRT1323072	hsa-miR-3689c	CLIP-seq
MIRT1323133	hsa-miR-3913-5p	CLIP-seq
MIRT1323134	hsa-miR-3938	CLIP-seq
MIRT1323135	hsa-miR-4262	CLIP-seq
MIRT1323136	hsa-miR-4266	CLIP-seq
MIRT1323137	hsa-miR-4272	CLIP-seq
MIRT1323075	hsa-miR-4291	CLIP-seq
MIRT1323138	hsa-miR-4298	CLIP-seq
MIRT1323077	hsa-miR-4420	CLIP-seq
MIRT1323078	hsa-miR-4428	CLIP-seq
MIRT1323079	hsa-miR-4436b-5p	CLIP-seq
MIRT1323080	hsa-miR-4438	CLIP-seq
MIRT1323139	hsa-miR-4468	CLIP-seq
MIRT1323081	hsa-miR-4476	CLIP-seq
MIRT1323083	hsa-miR-4488	CLIP-seq
MIRT1323084	hsa-miR-450b-5p	CLIP-seq
MIRT1323085	hsa-miR-4529-5p	CLIP-seq
MIRT1323086	hsa-miR-4533	CLIP-seq
MIRT1323087	hsa-miR-4534	CLIP-seq
MIRT1323088	hsa-miR-455-3p	CLIP-seq
MIRT1323089	hsa-miR-4645-5p	CLIP-seq
MIRT1323091	hsa-miR-4649-3p	CLIP-seq
MIRT1323092	hsa-miR-4656	CLIP-seq
MIRT1323093	hsa-miR-4665-5p	CLIP-seq
MIRT1323094	hsa-miR-4668-5p	CLIP-seq
MIRT1323095	hsa-miR-4673	CLIP-seq
MIRT1323140	hsa-miR-4681	CLIP-seq
MIRT1323096	hsa-miR-4694-5p	CLIP-seq
MIRT1323141	hsa-miR-4695-5p	CLIP-seq
MIRT1323097	hsa-miR-4697-5p	CLIP-seq
MIRT1323100	hsa-miR-4726-3p	CLIP-seq
MIRT1323101	hsa-miR-4728-5p	CLIP-seq
MIRT1323102	hsa-miR-4742-5p	CLIP-seq
MIRT1323142	hsa-miR-4755-5p	CLIP-seq
MIRT1323104	hsa-miR-4765	CLIP-seq
MIRT1323143	hsa-miR-4777-5p	CLIP-seq
MIRT1323144	hsa-miR-4779	CLIP-seq
MIRT1323145	hsa-miR-4789-3p	CLIP-seq
MIRT1323146	hsa-miR-483-5p	CLIP-seq
MIRT1323106	hsa-miR-507	CLIP-seq
MIRT1323107	hsa-miR-5095	CLIP-seq
MIRT1323147	hsa-miR-5096	CLIP-seq
MIRT1323148	hsa-miR-542-3p	CLIP-seq
MIRT1323149	hsa-miR-552	CLIP-seq
MIRT1323108	hsa-miR-557	CLIP-seq
MIRT1323150	hsa-miR-561	CLIP-seq
MIRT1323151	hsa-miR-587	CLIP-seq
MIRT1323152	hsa-miR-600	CLIP-seq
MIRT1323153	hsa-miR-601	CLIP-seq
MIRT1323154	hsa-miR-623	CLIP-seq
MIRT1323155	hsa-miR-641	CLIP-seq
MIRT1323156	hsa-miR-642b	CLIP-seq
MIRT1323110	hsa-miR-645	CLIP-seq
MIRT1323157	hsa-miR-7	CLIP-seq
MIRT1323111	hsa-miR-891b	CLIP-seq
MIRT1323112	hsa-miR-892b	CLIP-seq
MIRT1323131	hsa-miR-3185	CLIP-seq
MIRT1323052	hsa-miR-122	CLIP-seq
MIRT1323113	hsa-miR-1246	CLIP-seq
MIRT1323114	hsa-miR-1252	CLIP-seq
MIRT1323115	hsa-miR-1255a	CLIP-seq
MIRT1323116	hsa-miR-1255b	CLIP-seq
MIRT1323118	hsa-miR-1302	CLIP-seq
MIRT1323057	hsa-miR-1911	CLIP-seq
MIRT1323061	hsa-miR-198	CLIP-seq
MIRT1323125	hsa-miR-204	CLIP-seq
MIRT1323126	hsa-miR-211	CLIP-seq
MIRT1323062	hsa-miR-2110	CLIP-seq
MIRT1323064	hsa-miR-3065-3p	CLIP-seq
MIRT1323065	hsa-miR-3120-3p	CLIP-seq
MIRT1323128	hsa-miR-3122	CLIP-seq
MIRT1323129	hsa-miR-3148	CLIP-seq
MIRT1323130	hsa-miR-3173-3p	CLIP-seq
MIRT1323066	hsa-miR-3174	CLIP-seq
MIRT1323131	hsa-miR-3185	CLIP-seq
MIRT1323069	hsa-miR-323-3p	CLIP-seq
MIRT2095861	hsa-miR-3616-3p	CLIP-seq
MIRT1323132	hsa-miR-3617	CLIP-seq
MIRT1323070	hsa-miR-3678-3p	CLIP-seq
MIRT1323071	hsa-miR-3689a-3p	CLIP-seq
MIRT1323072	hsa-miR-3689c	CLIP-seq
MIRT1323133	hsa-miR-3913-5p	CLIP-seq
MIRT1323134	hsa-miR-3938	CLIP-seq
MIRT2095862	hsa-miR-4254	CLIP-seq
MIRT1323074	hsa-miR-4271	CLIP-seq
MIRT1323137	hsa-miR-4272	CLIP-seq
MIRT1323075	hsa-miR-4291	CLIP-seq
MIRT1323138	hsa-miR-4298	CLIP-seq
MIRT1323078	hsa-miR-4428	CLIP-seq
MIRT1323079	hsa-miR-4436b-5p	CLIP-seq
MIRT1323080	hsa-miR-4438	CLIP-seq
MIRT1323081	hsa-miR-4476	CLIP-seq
MIRT1323082	hsa-miR-4481	CLIP-seq
MIRT1323084	hsa-miR-450b-5p	CLIP-seq
MIRT1323086	hsa-miR-4533	CLIP-seq
MIRT1323087	hsa-miR-4534	CLIP-seq
MIRT1323088	hsa-miR-455-3p	CLIP-seq
MIRT1323089	hsa-miR-4645-5p	CLIP-seq
MIRT1323094	hsa-miR-4668-5p	CLIP-seq
MIRT1323095	hsa-miR-4673	CLIP-seq
MIRT1323140	hsa-miR-4681	CLIP-seq
MIRT1323099	hsa-miR-4725-3p	CLIP-seq
MIRT1323101	hsa-miR-4728-5p	CLIP-seq
MIRT1323102	hsa-miR-4742-5p	CLIP-seq
MIRT1323103	hsa-miR-4745-5p	CLIP-seq
MIRT1323142	hsa-miR-4755-5p	CLIP-seq
MIRT1323104	hsa-miR-4765	CLIP-seq
MIRT1323143	hsa-miR-4777-5p	CLIP-seq
MIRT1323145	hsa-miR-4789-3p	CLIP-seq
MIRT1323146	hsa-miR-483-5p	CLIP-seq
MIRT1323105	hsa-miR-491-5p	CLIP-seq
MIRT1323106	hsa-miR-507	CLIP-seq
MIRT1323107	hsa-miR-5095	CLIP-seq
MIRT1323148	hsa-miR-542-3p	CLIP-seq
MIRT1323108	hsa-miR-557	CLIP-seq
MIRT1323151	hsa-miR-587	CLIP-seq
MIRT1323109	hsa-miR-598	CLIP-seq
MIRT1323153	hsa-miR-601	CLIP-seq
MIRT2095863	hsa-miR-619	CLIP-seq
MIRT1323154	hsa-miR-623	CLIP-seq
MIRT1323155	hsa-miR-641	CLIP-seq
MIRT1323156	hsa-miR-642b	CLIP-seq
MIRT1323157	hsa-miR-7	CLIP-seq
MIRT1323111	hsa-miR-891b	CLIP-seq
MIRT1323064	hsa-miR-3065-3p	CLIP-seq
MIRT1323075	hsa-miR-4291	CLIP-seq
MIRT1323053	hsa-miR-1237	CLIP-seq
MIRT1323113	hsa-miR-1246	CLIP-seq
MIRT1323054	hsa-miR-1248	CLIP-seq
MIRT1323115	hsa-miR-1255a	CLIP-seq
MIRT1323116	hsa-miR-1255b	CLIP-seq
MIRT1323055	hsa-miR-1275	CLIP-seq
MIRT1323118	hsa-miR-1302	CLIP-seq
MIRT1323119	hsa-miR-140-3p	CLIP-seq
MIRT1323056	hsa-miR-1827	CLIP-seq
MIRT1323057	hsa-miR-1911	CLIP-seq
MIRT1323059	hsa-miR-193a-3p	CLIP-seq
MIRT1323060	hsa-miR-193b	CLIP-seq
MIRT1323124	hsa-miR-197	CLIP-seq
MIRT1323061	hsa-miR-198	CLIP-seq
MIRT1323064	hsa-miR-3065-3p	CLIP-seq
MIRT1323065	hsa-miR-3120-3p	CLIP-seq
MIRT1323128	hsa-miR-3122	CLIP-seq
MIRT1323130	hsa-miR-3173-3p	CLIP-seq
MIRT1323066	hsa-miR-3174	CLIP-seq
MIRT1323131	hsa-miR-3185	CLIP-seq
MIRT1323069	hsa-miR-323-3p	CLIP-seq
MIRT1323070	hsa-miR-3678-3p	CLIP-seq
MIRT1323073	hsa-miR-3692	CLIP-seq
MIRT1323133	hsa-miR-3913-5p	CLIP-seq
MIRT1323075	hsa-miR-4291	CLIP-seq
MIRT1323138	hsa-miR-4298	CLIP-seq
MIRT1323078	hsa-miR-4428	CLIP-seq
MIRT1323079	hsa-miR-4436b-5p	CLIP-seq
MIRT1323081	hsa-miR-4476	CLIP-seq
MIRT1323083	hsa-miR-4488	CLIP-seq
MIRT1323084	hsa-miR-450b-5p	CLIP-seq
MIRT1323086	hsa-miR-4533	CLIP-seq
MIRT1323088	hsa-miR-455-3p	CLIP-seq
MIRT1323089	hsa-miR-4645-5p	CLIP-seq
MIRT1323091	hsa-miR-4649-3p	CLIP-seq
MIRT1323092	hsa-miR-4656	CLIP-seq
MIRT1323093	hsa-miR-4665-5p	CLIP-seq
MIRT1323095	hsa-miR-4673	CLIP-seq
MIRT1323097	hsa-miR-4697-5p	CLIP-seq
MIRT1323098	hsa-miR-4699-5p	CLIP-seq
MIRT1323104	hsa-miR-4765	CLIP-seq
MIRT1323143	hsa-miR-4777-5p	CLIP-seq
MIRT1323106	hsa-miR-507	CLIP-seq
MIRT1323107	hsa-miR-5095	CLIP-seq
MIRT1323108	hsa-miR-557	CLIP-seq
MIRT1323151	hsa-miR-587	CLIP-seq
MIRT1323109	hsa-miR-598	CLIP-seq
MIRT1323153	hsa-miR-601	CLIP-seq
MIRT1323110	hsa-miR-645	CLIP-seq
MIRT1323112	hsa-miR-892b	CLIP-seq
MIRT1323113	hsa-miR-1246	CLIP-seq
MIRT1323115	hsa-miR-1255a	CLIP-seq
MIRT1323116	hsa-miR-1255b	CLIP-seq
MIRT1323130	hsa-miR-3173-3p	CLIP-seq
MIRT1323131	hsa-miR-3185	CLIP-seq
MIRT1323079	hsa-miR-4436b-5p	CLIP-seq
MIRT1323088	hsa-miR-455-3p	CLIP-seq
MIRT1323143	hsa-miR-4777-5p	CLIP-seq
MIRT1323107	hsa-miR-5095	CLIP-seq
MIRT1323153	hsa-miR-601	CLIP-seq
MIRT1323113	hsa-miR-1246	CLIP-seq
MIRT1323115	hsa-miR-1255a	CLIP-seq
MIRT1323116	hsa-miR-1255b	CLIP-seq
MIRT1323131	hsa-miR-3185	CLIP-seq
MIRT1323070	hsa-miR-3678-3p	CLIP-seq
MIRT1323079	hsa-miR-4436b-5p	CLIP-seq
MIRT1323084	hsa-miR-450b-5p	CLIP-seq
MIRT1323088	hsa-miR-455-3p	CLIP-seq
MIRT1323143	hsa-miR-4777-5p	CLIP-seq
MIRT1323106	hsa-miR-507	CLIP-seq
MIRT1323108	hsa-miR-557	CLIP-seq
MIRT1323151	hsa-miR-587	CLIP-seq
MIRT1323153	hsa-miR-601	CLIP-seq
MIRT1323113	hsa-miR-1246	CLIP-seq
MIRT1323115	hsa-miR-1255a	CLIP-seq
MIRT1323116	hsa-miR-1255b	CLIP-seq
MIRT1323131	hsa-miR-3185	CLIP-seq
MIRT1323079	hsa-miR-4436b-5p	CLIP-seq
MIRT1323088	hsa-miR-455-3p	CLIP-seq
MIRT1323113	hsa-miR-1246	CLIP-seq
MIRT1323114	hsa-miR-1252	CLIP-seq
MIRT1323115	hsa-miR-1255a	CLIP-seq
MIRT1323116	hsa-miR-1255b	CLIP-seq
MIRT1323125	hsa-miR-204	CLIP-seq
MIRT1323126	hsa-miR-211	CLIP-seq
MIRT1323129	hsa-miR-3148	CLIP-seq
MIRT1323130	hsa-miR-3173-3p	CLIP-seq
MIRT1323131	hsa-miR-3185	CLIP-seq
MIRT1323132	hsa-miR-3617	CLIP-seq
MIRT1323070	hsa-miR-3678-3p	CLIP-seq
MIRT1323134	hsa-miR-3938	CLIP-seq
MIRT1323079	hsa-miR-4436b-5p	CLIP-seq
MIRT1323081	hsa-miR-4476	CLIP-seq
MIRT1323084	hsa-miR-450b-5p	CLIP-seq
MIRT1323086	hsa-miR-4533	CLIP-seq
MIRT1323088	hsa-miR-455-3p	CLIP-seq
MIRT1323094	hsa-miR-4668-5p	CLIP-seq
MIRT1323140	hsa-miR-4681	CLIP-seq
MIRT1323142	hsa-miR-4755-5p	CLIP-seq
MIRT1323143	hsa-miR-4777-5p	CLIP-seq
MIRT1323146	hsa-miR-483-5p	CLIP-seq
MIRT1323106	hsa-miR-507	CLIP-seq
MIRT1323108	hsa-miR-557	CLIP-seq
MIRT1323151	hsa-miR-587	CLIP-seq
MIRT1323153	hsa-miR-601	CLIP-seq
MIRT1323154	hsa-miR-623	CLIP-seq
MIRT1323155	hsa-miR-641	CLIP-seq
MIRT1323157	hsa-miR-7	CLIP-seq
MIRT1323113	hsa-miR-1246	CLIP-seq
MIRT1323114	hsa-miR-1252	CLIP-seq
MIRT1323115	hsa-miR-1255a	CLIP-seq
MIRT1323116	hsa-miR-1255b	CLIP-seq
MIRT1323125	hsa-miR-204	CLIP-seq
MIRT1323126	hsa-miR-211	CLIP-seq
MIRT1323129	hsa-miR-3148	CLIP-seq
MIRT1323130	hsa-miR-3173-3p	CLIP-seq
MIRT1323131	hsa-miR-3185	CLIP-seq
MIRT1323132	hsa-miR-3617	CLIP-seq
MIRT1323070	hsa-miR-3678-3p	CLIP-seq
MIRT1323134	hsa-miR-3938	CLIP-seq
MIRT2095862	hsa-miR-4254	CLIP-seq
MIRT1323079	hsa-miR-4436b-5p	CLIP-seq
MIRT1323081	hsa-miR-4476	CLIP-seq
MIRT1323084	hsa-miR-450b-5p	CLIP-seq
MIRT1323086	hsa-miR-4533	CLIP-seq
MIRT1323088	hsa-miR-455-3p	CLIP-seq
MIRT1323094	hsa-miR-4668-5p	CLIP-seq
MIRT1323140	hsa-miR-4681	CLIP-seq
MIRT1323142	hsa-miR-4755-5p	CLIP-seq
MIRT1323143	hsa-miR-4777-5p	CLIP-seq
MIRT1323146	hsa-miR-483-5p	CLIP-seq
MIRT1323106	hsa-miR-507	CLIP-seq
MIRT1323108	hsa-miR-557	CLIP-seq
MIRT1323151	hsa-miR-587	CLIP-seq
MIRT1323153	hsa-miR-601	CLIP-seq
MIRT2095863	hsa-miR-619	CLIP-seq
MIRT1323154	hsa-miR-623	CLIP-seq
MIRT1323155	hsa-miR-641	CLIP-seq
MIRT1323157	hsa-miR-7	CLIP-seq

Gene ontology (GO) Show/Hide all (21)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000209	Process	Protein polyubiquitination	IDA	19365808
GO:0003779	Function	Actin binding	IEA
GO:0003779	Function	Actin binding	ISS
GO:0005515	Function	Protein binding	IPI	19365808, 25416956, 31515488, 32296183, 32814053
GO:0005634	Component	Nucleus	IEA
GO:0005737	Component	Cytoplasm	IEA
GO:0005768	Component	Endosome	IEA
GO:0005769	Component	Early endosome	IEA
GO:0005769	Component	Early endosome	ISS
GO:0005794	Component	Golgi apparatus	IEA
GO:0005794	Component	Golgi apparatus	ISS
GO:0005829	Component	Cytosol	IDA
GO:0005856	Component	Cytoskeleton	IEA
GO:0005874	Component	Microtubule	IEA
GO:0014069	Component	Postsynaptic density	IEA
GO:0015630	Component	Microtubule cytoskeleton	IEA
GO:0015630	Component	Microtubule cytoskeleton	ISS
GO:0031410	Component	Cytoplasmic vesicle	IBA
GO:0031410	Component	Cytoplasmic vesicle	IEA
GO:0031410	Component	Cytoplasmic vesicle	ISS
GO:0045202	Component	Synapse	IEA

Other IDs

• MIM: 617318
• HGNC: 17153
• e!Ensembl: ENSG00000160753

Protein

• UniProt ID: Q9BVN2
• Protein name: AP-4 complex accessory subunit RUSC1 (New molecule containing SH3 at the carboxy-terminus) (Nesca) (RUN and SH3 domain-containing protein 1)
• Protein function: Associates with the adapter-like complex 4 (AP-4) and may therefore play a role in vesicular trafficking of proteins at the trans-Golgi network (PubMed:30262884). Signaling adapter which plays a role in neuronal differentiation (PubMed:15024033)
• PDB: 4GIW
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF02759	RUN	530 → 665	RUN domain	Family
  PF14604	SH3_9	851 → 899	Variant SH3 domain	Domain

• Tissue specificity: TISSUE SPECIFICITY: Predominantly expressed in brain. {ECO:0000269|PubMed:15024033}.
• Sequence:

  MLSPQRALLCNLNHIHLQHVSLGLHLSRRPELQEGPLSTPPPPGDTGGKESRGPCSGTLV
  DANSNSPAVPCRCCQEHGPGLENRQDPSQEEEGAASPSDPGCSSSLSSCSDLSPDESPVS
  VYLRDLPGDEDAHPQPSIIPLEQGSPLASAGPGTCSPDSFCCSPDSCSGASSSPDPGLDS
  NCNALTTCQDVPSPGLEEEDERAEQDLPTSELLEADDGKIDAGKTEPSWKINPIWKIDTE
  KTKAEWKTTENNNTGWKNNGNVNSSWKSEPEKFDSGWKTNTRITDSGSKTDAGKIDGGWR
  SDVSEEPVPHRTITSFHELAQKRKRGPGLPLVPQAKKDRSDWLIVFSPDTELPPSGSPGG
  SSAPPREVTTFKELRSRSRAPAPPVPPRDPPVGWALVPPRPPPPPVPPRRKKNRPGLQPI
  AEGQSEEGRAVSPAAGEEAPAAKEPGAQAGLEVRSSWSFAGVPGAQRLWMAEAQSGTGQL
  QEQKKGLLIAVSVSVDKIISHFGAARNLVQKAQLGDSRLSPDVGHLVLTTLCPALHALVA
  DGLKPFRKDLITGQRRSSPWSVVEASVKPGSSTRSLGTLYSQVSRLAPLSSSRSRFHAFI
  LGLLNTKQLELWFSSLQEDAGLLSLLYLPTGFFSLARGGCPSLSTELLLLLQPLSVLTFH
  LDLLFEHHHHLPLGPPQAPAPPGPPPALQQTMQAMLHFGGRLAQSLRGTSKEAASDPSDS
  PNLPTPGSWWEQLTQASRVYASGGTEGFPLSRWAPGRHGTAAEEGAQERPLPTDEMAPGR
  GLWLGRLFGVPGGPAENENGALKSRRPSSWLPPTVSVLALVKRGAPPEMPSPQELEASAP
  RMVQTHRAVRALCDHTAARPDQLSFRRGEVLRVITTVDEDWLRCGRDGMEGLVPVGYTSL
  VL

• Sequence length: 902

Related Genes

No strongly related genes found yet for RUSC1.

Diseases Linked via Similar Genes

No additional diseases found yet through genes similar to RUSC1.