RTL10 (retrotransposon Gag like 10)

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Gene miRNA Gene ontology Other IDs Protein Diseases linked via similar genes

Gene

• Entrez ID: 79680
• Gene name: Retrotransposon Gag like 10
• Gene symbol: RTL10
• Synonyms (NCBI Gene): BOP, C22orf29
• Chromosome: 22
• Chromosome location: 22q11.21

miRNA Show/Hide all (36)

miRTarBase ID	miRNA	Experiments	Reference
MIRT672869	hsa-miR-6813-3p	HITS-CLIP	23824327
MIRT676603	hsa-miR-759	HITS-CLIP	23824327
MIRT672868	hsa-miR-125a-3p	HITS-CLIP	23824327
MIRT672867	hsa-miR-764	HITS-CLIP	23824327
MIRT672866	hsa-miR-3934-5p	HITS-CLIP	23824327
MIRT672865	hsa-miR-1224-3p	HITS-CLIP	23824327
MIRT672864	hsa-miR-212-5p	HITS-CLIP	23824327
MIRT676602	hsa-miR-4635	HITS-CLIP	23824327
MIRT672862	hsa-miR-4680-5p	HITS-CLIP	23824327
MIRT672861	hsa-miR-6790-3p	HITS-CLIP	23824327
MIRT672860	hsa-miR-6821-3p	HITS-CLIP	23824327
MIRT672858	hsa-miR-4757-5p	HITS-CLIP	23824327
MIRT672857	hsa-miR-6744-3p	HITS-CLIP	23824327
MIRT672856	hsa-miR-378a-5p	HITS-CLIP	23824327
MIRT672855	hsa-miR-7158-3p	HITS-CLIP	23824327
MIRT672854	hsa-miR-203b-3p	HITS-CLIP	23824327
MIRT672853	hsa-miR-640	HITS-CLIP	23824327
MIRT672852	hsa-miR-6878-3p	HITS-CLIP	23824327
MIRT672869	hsa-miR-6813-3p	HITS-CLIP	23824327
MIRT672868	hsa-miR-125a-3p	HITS-CLIP	23824327
MIRT672867	hsa-miR-764	HITS-CLIP	23824327
MIRT672866	hsa-miR-3934-5p	HITS-CLIP	23824327
MIRT672865	hsa-miR-1224-3p	HITS-CLIP	23824327
MIRT672864	hsa-miR-212-5p	HITS-CLIP	23824327
MIRT672863	hsa-miR-3653-5p	HITS-CLIP	23824327
MIRT672862	hsa-miR-4680-5p	HITS-CLIP	23824327
MIRT672861	hsa-miR-6790-3p	HITS-CLIP	23824327
MIRT672860	hsa-miR-6821-3p	HITS-CLIP	23824327
MIRT672859	hsa-miR-6778-3p	HITS-CLIP	23824327
MIRT672858	hsa-miR-4757-5p	HITS-CLIP	23824327
MIRT672857	hsa-miR-6744-3p	HITS-CLIP	23824327
MIRT672856	hsa-miR-378a-5p	HITS-CLIP	23824327
MIRT672855	hsa-miR-7158-3p	HITS-CLIP	23824327
MIRT672854	hsa-miR-203b-3p	HITS-CLIP	23824327
MIRT672853	hsa-miR-640	HITS-CLIP	23824327
MIRT672852	hsa-miR-6878-3p	HITS-CLIP	23824327

Gene ontology (GO) Show/Hide all (7)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005515	Function	Protein binding	IPI	23055042, 27107012, 33961781
GO:0005739	Component	Mitochondrion	IBA
GO:0005739	Component	Mitochondrion	IDA	23055042
GO:0005739	Component	Mitochondrion	IEA
GO:0006915	Process	Apoptotic process	IEA
GO:0051881	Process	Regulation of mitochondrial membrane potential	IMP	23055042
GO:0097345	Process	Mitochondrial outer membrane permeabilization	IMP	23055042

Other IDs

• MIM: 620751
• HGNC: 26112
• e!Ensembl: ENSG00000215012

Protein

• UniProt ID: Q7L3V2
• Protein name: Protein Bop (BH3-only protein) (Retrotransposon Gag-like protein 10)
• Protein function: Could induce apoptosis in a BH3 domain-dependent manner. The direct interaction network of Bcl-2 family members may play a key role in modulation RTL10/BOP intrinsic apoptotic signaling activity.
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF16297	DUF4939	84 → 183	Domain of unknown function (DUF4939)	Family

• Tissue specificity: TISSUE SPECIFICITY: Ubiquitously expressed. {ECO:0000269|PubMed:23055042}.
• Sequence:

  MPRGRCRQQGPRIPIWAAANYANAHPWQQMDKASPGVAYTPLVDPWIERPCCGDTVCVRT
  TMEQKSTASGTCGGKPAERGPLAGHMPSSRPHRVDFCWVPGSDPGTFDGSPWLLDRFLAQ
  LGDYMSFHFEHYQDNISRVCEILRRLTGRAQAWAAPYLDGDLPLPDDYELFCQDLKEVVQ
  DPNSFAEYHAVVTCPLPLASSQLPVAPQLPVVRQYLARFLEGLALDMGTAPRSLPAAMAT
  PAVSGSNSVSRSALFEQQLTKESTPGPKEPPVLPSSTCSSKPGPVEPASSQPEEAAPTPV
  PRLSESANPPAQRPDPAHPGGPKPQKTEEEVLETEGDQEVSLGTPQEVVEAPETPGEPPL
  SPGF

• Sequence length: 364

Related Genes

No strongly related genes found yet for RTL10.

Diseases Linked via Similar Genes

No additional diseases found yet through genes similar to RTL10.