RSAD1 (radical S-adenosyl methionine domain containing 1)

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Gene miRNA Gene ontology Other IDs Protein Related genes Diseases linked via similar genes

Gene

• Entrez ID: 55316
• Gene name: Radical S-adenosyl methionine domain containing 1
• Gene symbol: RSAD1
• Synonyms (NCBI Gene): HemW
• Chromosome: 17
• Chromosome location: 17q21.33

miRNA Show/Hide all (105)

miRTarBase ID	miRNA	Experiments	Reference
MIRT022676	hsa-miR-124-3p	Microarray	18668037
MIRT1320854	hsa-miR-1200	CLIP-seq
MIRT1320855	hsa-miR-214	CLIP-seq
MIRT1320856	hsa-miR-3074-5p	CLIP-seq
MIRT1320857	hsa-miR-3619-5p	CLIP-seq
MIRT1320858	hsa-miR-369-3p	CLIP-seq
MIRT1320859	hsa-miR-4291	CLIP-seq
MIRT1320860	hsa-miR-4433	CLIP-seq
MIRT1320861	hsa-miR-4652-3p	CLIP-seq
MIRT1320862	hsa-miR-4722-5p	CLIP-seq
MIRT1320863	hsa-miR-4786-5p	CLIP-seq
MIRT1320864	hsa-miR-761	CLIP-seq
MIRT1320865	hsa-miR-769-5p	CLIP-seq
MIRT1320866	hsa-miR-922	CLIP-seq
MIRT2095246	hsa-miR-1206	CLIP-seq
MIRT2095247	hsa-miR-1208	CLIP-seq
MIRT2095248	hsa-miR-1237	CLIP-seq
MIRT2095249	hsa-miR-1248	CLIP-seq
MIRT2095250	hsa-miR-141	CLIP-seq
MIRT2095251	hsa-miR-1976	CLIP-seq
MIRT2095252	hsa-miR-200a	CLIP-seq
MIRT2095253	hsa-miR-4528	CLIP-seq
MIRT2095254	hsa-miR-4643	CLIP-seq
MIRT2095255	hsa-miR-4768-5p	CLIP-seq
MIRT2095256	hsa-miR-4781-3p	CLIP-seq
MIRT1320863	hsa-miR-4786-5p	CLIP-seq
MIRT2095257	hsa-miR-4789-3p	CLIP-seq
MIRT2095258	hsa-miR-4802-3p	CLIP-seq
MIRT2095259	hsa-miR-490-5p	CLIP-seq
MIRT2095260	hsa-miR-515-5p	CLIP-seq
MIRT2095261	hsa-miR-642b	CLIP-seq
MIRT1320865	hsa-miR-769-5p	CLIP-seq
MIRT2319606	hsa-miR-1184	CLIP-seq
MIRT1320854	hsa-miR-1200	CLIP-seq
MIRT2319607	hsa-miR-1205	CLIP-seq
MIRT2095248	hsa-miR-1237	CLIP-seq
MIRT2095249	hsa-miR-1248	CLIP-seq
MIRT2319608	hsa-miR-1253	CLIP-seq
MIRT2319609	hsa-miR-1287	CLIP-seq
MIRT2319610	hsa-miR-1293	CLIP-seq
MIRT2095250	hsa-miR-141	CLIP-seq
MIRT2319611	hsa-miR-147	CLIP-seq
MIRT2319612	hsa-miR-193a-3p	CLIP-seq
MIRT2319613	hsa-miR-193b	CLIP-seq
MIRT2095252	hsa-miR-200a	CLIP-seq
MIRT1320855	hsa-miR-214	CLIP-seq
MIRT2319614	hsa-miR-24	CLIP-seq
MIRT2319615	hsa-miR-299-3p	CLIP-seq
MIRT2319616	hsa-miR-302f	CLIP-seq
MIRT1320856	hsa-miR-3074-5p	CLIP-seq
MIRT2319617	hsa-miR-30a	CLIP-seq
MIRT2319618	hsa-miR-30b	CLIP-seq
MIRT2319619	hsa-miR-30c	CLIP-seq
MIRT2319620	hsa-miR-30d	CLIP-seq
MIRT2319621	hsa-miR-30e	CLIP-seq
MIRT2319622	hsa-miR-3117-3p	CLIP-seq
MIRT2319623	hsa-miR-3119	CLIP-seq
MIRT2319624	hsa-miR-3135b	CLIP-seq
MIRT2319625	hsa-miR-3145-5p	CLIP-seq
MIRT2319626	hsa-miR-3158-5p	CLIP-seq
MIRT2319627	hsa-miR-3160-5p	CLIP-seq
MIRT2319628	hsa-miR-3174	CLIP-seq
MIRT2319629	hsa-miR-3182	CLIP-seq
MIRT2319630	hsa-miR-3184	CLIP-seq
MIRT2319631	hsa-miR-346	CLIP-seq
MIRT1320857	hsa-miR-3619-5p	CLIP-seq
MIRT1320858	hsa-miR-369-3p	CLIP-seq
MIRT2319632	hsa-miR-3911	CLIP-seq
MIRT2319633	hsa-miR-3942-5p	CLIP-seq
MIRT2319634	hsa-miR-423-5p	CLIP-seq
MIRT2319635	hsa-miR-4267	CLIP-seq
MIRT2319636	hsa-miR-4283	CLIP-seq
MIRT2319637	hsa-miR-4288	CLIP-seq
MIRT2319638	hsa-miR-4434	CLIP-seq
MIRT2319639	hsa-miR-4437	CLIP-seq
MIRT2319640	hsa-miR-4468	CLIP-seq
MIRT2319641	hsa-miR-4474-3p	CLIP-seq
MIRT2319642	hsa-miR-4483	CLIP-seq
MIRT2319643	hsa-miR-4516	CLIP-seq
MIRT2319644	hsa-miR-4530	CLIP-seq
MIRT2319645	hsa-miR-4536	CLIP-seq
MIRT2319646	hsa-miR-4638-3p	CLIP-seq
MIRT2095254	hsa-miR-4643	CLIP-seq
MIRT2319647	hsa-miR-4677-3p	CLIP-seq
MIRT2319648	hsa-miR-4690-5p	CLIP-seq
MIRT2319649	hsa-miR-4703-5p	CLIP-seq
MIRT2319650	hsa-miR-4765	CLIP-seq
MIRT2095256	hsa-miR-4781-3p	CLIP-seq
MIRT2095257	hsa-miR-4789-3p	CLIP-seq
MIRT2095258	hsa-miR-4802-3p	CLIP-seq
MIRT2095259	hsa-miR-490-5p	CLIP-seq
MIRT2319651	hsa-miR-508-5p	CLIP-seq
MIRT2095260	hsa-miR-515-5p	CLIP-seq
MIRT2319652	hsa-miR-548ag	CLIP-seq
MIRT2319653	hsa-miR-548ai	CLIP-seq
MIRT2319654	hsa-miR-548m	CLIP-seq
MIRT2319655	hsa-miR-550b	CLIP-seq
MIRT2319656	hsa-miR-551a	CLIP-seq
MIRT2319657	hsa-miR-551b	CLIP-seq
MIRT2319658	hsa-miR-632	CLIP-seq
MIRT2095261	hsa-miR-642b	CLIP-seq
MIRT2319659	hsa-miR-644	CLIP-seq
MIRT2319660	hsa-miR-654-3p	CLIP-seq
MIRT1320864	hsa-miR-761	CLIP-seq
MIRT2319661	hsa-miR-892b	CLIP-seq

Gene ontology (GO) Show/Hide all (13)

GO ID	Ontology	Definition	Evidence	Reference
GO:0003824	Function	Catalytic activity	IEA
GO:0004109	Function	Coproporphyrinogen oxidase activity	IEA
GO:0005737	Component	Cytoplasm	IBA
GO:0005737	Component	Cytoplasm	IEA
GO:0005739	Component	Mitochondrion	HTP	34800366
GO:0005739	Component	Mitochondrion	IEA
GO:0006779	Process	Porphyrin-containing compound biosynthetic process	IBA
GO:0006779	Process	Porphyrin-containing compound biosynthetic process	IEA
GO:0020037	Function	Heme binding	IDA	29282292
GO:0046872	Function	Metal ion binding	IEA
GO:0051536	Function	Iron-sulfur cluster binding	IEA
GO:0051539	Function	4 iron, 4 sulfur cluster binding	IBA
GO:0051539	Function	4 iron, 4 sulfur cluster binding	IEA

Other IDs

• MIM: 620590
• HGNC: 25634
• e!Ensembl: ENSG00000136444

Protein

• UniProt ID: Q9HA92
• Protein name: Radical S-adenosyl methionine domain-containing protein 1, mitochondrial (Putative heme chaperone)
• Protein function: May be a heme chaperone, appears to bind heme. Homologous bacterial proteins do not have oxygen-independent coproporphyrinogen-III oxidase activity (Probable). Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchange
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF04055	Radical_SAM	43 → 208	Radical SAM superfamily	Domain
  PF06969	HemN_C	346 → 414	HemN C-terminal domain	Domain

• Sequence:

  MALPGARARGWAAAARAAQRRRRVENAGGSPSPEPAGRRAALYVHWPYCEKRCSYCNFNK
  YIPRRLEEAAMQKCLVTEAQTLLRLSGVQRVESVFFGGGTPSLASPHTVAAVLEAVAQAA
  HLPADLEVTLEANPTSAPGSRLAEFGAAGVNRLSIGLQSLDDTELRLLGRTHSACDALRT
  LAEARRLFPGRVSVDLMLGLPAQQVGPWLGQLQELLHHCDDHLSLYQLSLERGTALFAQV
  QRGALPAPDPELAAEMYQRGRAVLREAGFHQYEVSNFARNGALSTHNWTYWQCGQYLGVG
  PGAHGRFMPQGAGGHTREARIQTLEPDNWMKEVMLFGHGTRKRVPLGRLELLEEVLALGL
  RTDVGITHQHWQQFEPQLTLWDVFGANKEVQELLERGLLQLDHRGLRCSWEGLAVLDSLL
  LTLLPQLQEAWQQRTPSPVPGG

• Sequence length: 442

Related Genes

No strongly related genes found yet for RSAD1.

Diseases Linked via Similar Genes

No additional diseases found yet through genes similar to RSAD1.