RPUSD2 (RNA pseudouridine synthase domain containing 2)

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Gene miRNA Gene ontology Other IDs Protein Related genes Diseases linked via similar genes

Gene

• Entrez ID: 27079
• Gene name: RNA pseudouridine synthase domain containing 2
• Gene symbol: RPUSD2
• Synonyms (NCBI Gene): C15orf19, C18B11, PUS9
• Chromosome: 15
• Chromosome location: 15q15.1

miRNA Show/Hide all (44)

miRTarBase ID	miRNA	Experiments	Reference
MIRT026035	hsa-miR-196a-5p	Sequencing	20371350
MIRT032131	hsa-let-7d-5p	Sequencing	20371350
MIRT458837	hsa-miR-203b-5p	PAR-CLIP	23592263
MIRT458835	hsa-miR-6718-5p	PAR-CLIP	23592263
MIRT458836	hsa-miR-140-5p	PAR-CLIP	23592263
MIRT458834	hsa-miR-1324	PAR-CLIP	23592263
MIRT458833	hsa-miR-656-5p	PAR-CLIP	23592263
MIRT458832	hsa-miR-376a-2-5p	PAR-CLIP	23592263
MIRT458831	hsa-miR-1273g-5p	PAR-CLIP	23592263
MIRT458829	hsa-miR-6501-5p	PAR-CLIP	23592263
MIRT458830	hsa-miR-4727-3p	PAR-CLIP	23592263
MIRT458828	hsa-miR-4460	PAR-CLIP	23592263
MIRT458827	hsa-miR-1202	PAR-CLIP	23592263
MIRT458826	hsa-miR-3972	PAR-CLIP	23592263
MIRT458825	hsa-miR-5006-5p	PAR-CLIP	23592263
MIRT458837	hsa-miR-203b-5p	PAR-CLIP	23592263
MIRT458835	hsa-miR-6718-5p	PAR-CLIP	23592263
MIRT458836	hsa-miR-140-5p	PAR-CLIP	23592263
MIRT458834	hsa-miR-1324	PAR-CLIP	23592263
MIRT458833	hsa-miR-656-5p	PAR-CLIP	23592263
MIRT458832	hsa-miR-376a-2-5p	PAR-CLIP	23592263
MIRT458831	hsa-miR-1273g-5p	PAR-CLIP	23592263
MIRT458829	hsa-miR-6501-5p	PAR-CLIP	23592263
MIRT458830	hsa-miR-4727-3p	PAR-CLIP	23592263
MIRT458828	hsa-miR-4460	PAR-CLIP	23592263
MIRT458827	hsa-miR-1202	PAR-CLIP	23592263
MIRT458826	hsa-miR-3972	PAR-CLIP	23592263
MIRT458825	hsa-miR-5006-5p	PAR-CLIP	23592263
MIRT1319235	hsa-miR-1260	CLIP-seq
MIRT1319236	hsa-miR-1260b	CLIP-seq
MIRT1319237	hsa-miR-136	CLIP-seq
MIRT1319238	hsa-miR-1470	CLIP-seq
MIRT1319239	hsa-miR-188-3p	CLIP-seq
MIRT1319240	hsa-miR-3156-3p	CLIP-seq
MIRT1319241	hsa-miR-3187-3p	CLIP-seq
MIRT1319242	hsa-miR-362-5p	CLIP-seq
MIRT1319243	hsa-miR-4301	CLIP-seq
MIRT1319244	hsa-miR-4435	CLIP-seq
MIRT1319245	hsa-miR-4667-3p	CLIP-seq
MIRT1319246	hsa-miR-4701-5p	CLIP-seq
MIRT1319247	hsa-miR-500b	CLIP-seq
MIRT1319248	hsa-miR-515-5p	CLIP-seq
MIRT1319249	hsa-miR-548s	CLIP-seq
MIRT1319250	hsa-miR-588	CLIP-seq

Gene ontology (GO) Show/Hide all (11)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000455	Process	Enzyme-directed rRNA pseudouridine synthesis	IBA
GO:0001522	Process	Pseudouridine synthesis	IEA
GO:0003723	Function	RNA binding	HDA	22658674
GO:0003723	Function	RNA binding	IEA
GO:0006397	Process	MRNA processing	IEA
GO:0009451	Process	RNA modification	IEA
GO:0009982	Function	Pseudouridine synthase activity	IBA
GO:0009982	Function	Pseudouridine synthase activity	IDA	31477916, 35051350
GO:0009982	Function	Pseudouridine synthase activity	IEA
GO:0016853	Function	Isomerase activity	IEA
GO:1990481	Process	MRNA pseudouridine synthesis	IDA	31477916, 35051350

Other IDs

• MIM: HGNC
• HGNC: N/A
• e!Ensembl: HGNC

Protein

• UniProt ID: Q8IZ73
• Protein name: Pseudouridylate synthase RPUSD2 (EC 5.4.99.-) (RNA pseudouridylate synthase domain-containing protein 2)
• Protein function: Pseudouridine synthase that catalyzes pseudouridylation of mRNAs.
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF00849	PseudoU_synth_2	231 → 378	RNA pseudouridylate synthase	Family

• Sequence:

  MWLDRRGWLRVLGHWRYDLRRPSFTRTWSGDKGPMAETVSTQVGTEGGLRASHQQNGDAG
  GDAKVELSPGPPKPAGREVEPAPVGGEHPSAAAPGPGKHKKRRGATRERVVPPPKKRRTG
  VSFGDEHFAETSYYFEGGLRKVRPYYFDFRTYCKGRWVGHSLLHVFSTEFRAQPLAYYEA
  AVRAGRLQLNEKPVQDLNIVLKDNDFLRNTVHRHEPPVTAEPIRLLAENEDVVVVDKPSS
  IPVHPCGRFRHNTVIFILGKEHQLKELHPLHRLDRLTSGVLMFAKTAAVSERIHEQVRDR
  QLEKEYVCRVEGEFPTEEVTCKEPILVVSYKVGVCRVDPRGKPCETVFQRLSYNGQSSVV
  RCRPLTGRTHQIRVHLQFLGHPILNDPIYNSVAWGPSRGRGGYIPKTNEELLRDLVAEHQ
  AKQSLDVLDLCEGDLSPGLTDSTAPSSELGKDDLEELAAAAQKMEEVAEAAPQELDTIAL
  ASEKAVETDVMNQETDPLCAECRLVRQDPLPQDLVMFLHALRYKGPGFEYFSPMPAWAQD
  DWQKD

• Sequence length: 545

Related Genes

No strongly related genes found yet for RPUSD2.

Diseases Linked via Similar Genes

No additional diseases found yet through genes similar to RPUSD2.