Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene SNPs Other IDs Associated diseases
Entrez ID	9252
Gene name	Ribosomal protein S6 kinase A5
Gene symbol	RPS6KA5
Synonyms (NCBI Gene)	MSK1MSPK1RLPK
Chromosome	14
Chromosome location	14q32.11

436

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miRTarBase ID	miRNA	Experiments	Reference
MIRT004504	hsa-miR-148a-3p	qRT-PCRLuciferase reporter assayWestern blot	20406806
MIRT004504	hsa-miR-148a-3p	qRT-PCRLuciferase reporter assayWestern blot	20406806
MIRT004504	hsa-miR-148a-3p	qRT-PCRLuciferase reporter assayWestern blot	20406806
MIRT022082	hsa-miR-128-3p	Sequencing	20371350
MIRT004504	hsa-miR-148a-3p	Reporter assay	20406806
MIRT027312	hsa-miR-101-3p	Sequencing	20371350
MIRT028694	hsa-miR-27a-3p	Sequencing	20371350
MIRT050647	hsa-miR-19a-3p	CLASH	23622248
MIRT048811	hsa-miR-93-5p	CLASH	23622248
MIRT037609	hsa-miR-744-5p	CLASH	23622248
MIRT611991	hsa-miR-5096	HITS-CLIP	23824327
MIRT611990	hsa-miR-335-3p	HITS-CLIP	23824327
MIRT611991	hsa-miR-5096	HITS-CLIP	23824327
MIRT611990	hsa-miR-335-3p	HITS-CLIP	23824327
MIRT626826	hsa-miR-6083	HITS-CLIP	23824327
MIRT611990	hsa-miR-335-3p	HITS-CLIP	23824327
MIRT654127	hsa-miR-1267	HITS-CLIP	23824327
MIRT654126	hsa-miR-367-5p	HITS-CLIP	23824327
MIRT654125	hsa-miR-6499-3p	HITS-CLIP	23824327
MIRT654124	hsa-miR-3135b	HITS-CLIP	23824327
MIRT654123	hsa-miR-504-3p	HITS-CLIP	23824327
MIRT654122	hsa-miR-122-5p	HITS-CLIP	23824327
MIRT654121	hsa-miR-3652	HITS-CLIP	23824327
MIRT654120	hsa-miR-4430	HITS-CLIP	23824327
MIRT654119	hsa-miR-3650	HITS-CLIP	23824327
MIRT654118	hsa-miR-143-5p	HITS-CLIP	23824327
MIRT654117	hsa-miR-6501-5p	HITS-CLIP	23824327
MIRT654116	hsa-miR-4423-5p	HITS-CLIP	23824327
MIRT654115	hsa-miR-744-3p	HITS-CLIP	23824327
MIRT654114	hsa-miR-5698	HITS-CLIP	23824327
MIRT654112	hsa-miR-4282	HITS-CLIP	23824327
MIRT654113	hsa-miR-526b-5p	HITS-CLIP	23824327
MIRT654111	hsa-miR-4446-5p	HITS-CLIP	23824327
MIRT626826	hsa-miR-6083	HITS-CLIP	23824327
MIRT611990	hsa-miR-335-3p	HITS-CLIP	23824327
MIRT626826	hsa-miR-6083	HITS-CLIP	23824327
MIRT611991	hsa-miR-5096	HITS-CLIP	23824327
MIRT611990	hsa-miR-335-3p	HITS-CLIP	23824327
MIRT611990	hsa-miR-335-3p	HITS-CLIP	23824327
MIRT611990	hsa-miR-335-3p	HITS-CLIP	23824327
MIRT626826	hsa-miR-6083	HITS-CLIP	23824327
MIRT611990	hsa-miR-335-3p	HITS-CLIP	23824327
MIRT611991	hsa-miR-5096	HITS-CLIP	23824327
MIRT611990	hsa-miR-335-3p	HITS-CLIP	23824327
MIRT611991	hsa-miR-5096	HITS-CLIP	23824327
MIRT611990	hsa-miR-335-3p	HITS-CLIP	23824327
MIRT611991	hsa-miR-5096	HITS-CLIP	23824327
MIRT611990	hsa-miR-335-3p	HITS-CLIP	23824327
MIRT611991	hsa-miR-5096	HITS-CLIP	23824327
MIRT611990	hsa-miR-335-3p	HITS-CLIP	23824327
MIRT534575	hsa-miR-20b-5p	PAR-CLIP	21572407
MIRT534574	hsa-miR-519d-3p	PAR-CLIP	21572407
MIRT534573	hsa-miR-20a-5p	PAR-CLIP	21572407
MIRT534572	hsa-miR-17-5p	PAR-CLIP	21572407
MIRT534571	hsa-miR-106b-5p	PAR-CLIP	21572407
MIRT534570	hsa-miR-106a-5p	PAR-CLIP	21572407
MIRT048811	hsa-miR-93-5p	PAR-CLIP	21572407
MIRT534569	hsa-miR-526b-3p	PAR-CLIP	21572407
MIRT534568	hsa-miR-5590-3p	PAR-CLIP	21572407
MIRT534567	hsa-miR-142-5p	PAR-CLIP	21572407
MIRT534566	hsa-miR-340-5p	PAR-CLIP	21572407
MIRT554613	hsa-miR-3609	PAR-CLIP	21572407
MIRT554612	hsa-miR-548ah-5p	PAR-CLIP	21572407
MIRT554611	hsa-miR-4796-3p	PAR-CLIP	21572407
MIRT554610	hsa-miR-519a-3p	PAR-CLIP	21572407
MIRT554609	hsa-miR-519b-3p	PAR-CLIP	21572407
MIRT554608	hsa-miR-519c-3p	PAR-CLIP	21572407
MIRT554607	hsa-miR-5003-3p	PAR-CLIP	21572407
MIRT534565	hsa-miR-1-5p	PAR-CLIP	21572407
MIRT554606	hsa-miR-485-3p	PAR-CLIP	21572407
MIRT554605	hsa-miR-539-3p	PAR-CLIP	21572407
MIRT546655	hsa-miR-301a-3p	PAR-CLIP	21572407
MIRT546658	hsa-miR-130b-3p	PAR-CLIP	21572407
MIRT546653	hsa-miR-301b-3p	PAR-CLIP	21572407
MIRT546656	hsa-miR-3666	PAR-CLIP	21572407
MIRT546657	hsa-miR-130a-3p	PAR-CLIP	21572407
MIRT546659	hsa-miR-4295	PAR-CLIP	21572407
MIRT546654	hsa-miR-454-3p	PAR-CLIP	21572407
MIRT546652	hsa-miR-376c-3p	PAR-CLIP	21572407
MIRT546651	hsa-miR-5586-3p	PAR-CLIP	21572407
MIRT546650	hsa-miR-6504-3p	PAR-CLIP	21572407
MIRT546649	hsa-miR-664a-3p	PAR-CLIP	21572407
MIRT546648	hsa-miR-16-2-3p	PAR-CLIP	21572407
MIRT546647	hsa-miR-195-3p	PAR-CLIP	21572407
MIRT546677	hsa-miR-548m	PAR-CLIP	21572407
MIRT546676	hsa-miR-18a-5p	PAR-CLIP	21572407
MIRT546675	hsa-miR-18b-5p	PAR-CLIP	21572407
MIRT546674	hsa-miR-4735-3p	PAR-CLIP	21572407
MIRT546673	hsa-miR-4728-3p	PAR-CLIP	21572407
MIRT546672	hsa-miR-3126-5p	PAR-CLIP	21572407
MIRT546671	hsa-miR-6875-5p	PAR-CLIP	21572407
MIRT546670	hsa-miR-4419a	PAR-CLIP	21572407
MIRT546669	hsa-miR-4510	PAR-CLIP	21572407
MIRT546668	hsa-miR-6127	PAR-CLIP	21572407
MIRT546667	hsa-miR-6129	PAR-CLIP	21572407
MIRT546666	hsa-miR-6130	PAR-CLIP	21572407
MIRT546665	hsa-miR-6133	PAR-CLIP	21572407
MIRT546663	hsa-miR-4663	PAR-CLIP	21572407
MIRT546664	hsa-miR-7160-5p	PAR-CLIP	21572407
MIRT546662	hsa-miR-8077	PAR-CLIP	21572407
MIRT546661	hsa-miR-6834-5p	PAR-CLIP	21572407
MIRT546660	hsa-miR-106a-3p	PAR-CLIP	21572407
MIRT546659	hsa-miR-4295	PAR-CLIP	21572407
MIRT546658	hsa-miR-130b-3p	PAR-CLIP	21572407
MIRT546657	hsa-miR-130a-3p	PAR-CLIP	21572407
MIRT546656	hsa-miR-3666	PAR-CLIP	21572407
MIRT546655	hsa-miR-301a-3p	PAR-CLIP	21572407
MIRT546654	hsa-miR-454-3p	PAR-CLIP	21572407
MIRT546653	hsa-miR-301b-3p	PAR-CLIP	21572407
MIRT546652	hsa-miR-376c-3p	PAR-CLIP	21572407
MIRT546651	hsa-miR-5586-3p	PAR-CLIP	21572407
MIRT546650	hsa-miR-6504-3p	PAR-CLIP	21572407
MIRT546649	hsa-miR-664a-3p	PAR-CLIP	21572407
MIRT546648	hsa-miR-16-2-3p	PAR-CLIP	21572407
MIRT546647	hsa-miR-195-3p	PAR-CLIP	21572407
MIRT534575	hsa-miR-20b-5p	PAR-CLIP	22012620
MIRT534574	hsa-miR-519d-3p	PAR-CLIP	22012620
MIRT534573	hsa-miR-20a-5p	PAR-CLIP	22012620
MIRT534572	hsa-miR-17-5p	PAR-CLIP	22012620
MIRT534571	hsa-miR-106b-5p	PAR-CLIP	22012620
MIRT534570	hsa-miR-106a-5p	PAR-CLIP	22012620
MIRT048811	hsa-miR-93-5p	PAR-CLIP	22012620
MIRT534569	hsa-miR-526b-3p	PAR-CLIP	22012620
MIRT534568	hsa-miR-5590-3p	PAR-CLIP	22012620
MIRT534567	hsa-miR-142-5p	PAR-CLIP	22012620
MIRT534566	hsa-miR-340-5p	PAR-CLIP	22012620
MIRT534565	hsa-miR-1-5p	PAR-CLIP	22012620
MIRT447726	hsa-miR-548n	PAR-CLIP	22100165
MIRT447725	hsa-miR-5088-5p	PAR-CLIP	22100165
MIRT447724	hsa-miR-4635	PAR-CLIP	22100165
MIRT447723	hsa-miR-24-3p	PAR-CLIP	22100165
MIRT447722	hsa-miR-4437	PAR-CLIP	22100165
MIRT447726	hsa-miR-548n	PAR-CLIP	22100165
MIRT447725	hsa-miR-5088-5p	PAR-CLIP	22100165
MIRT447724	hsa-miR-4635	PAR-CLIP	22100165
MIRT447723	hsa-miR-24-3p	PAR-CLIP	22100165
MIRT447722	hsa-miR-4437	PAR-CLIP	22100165
MIRT611990	hsa-miR-335-3p	HITS-CLIP	27418678
MIRT611991	hsa-miR-5096	HITS-CLIP	27418678
MIRT611991	hsa-miR-5096	HITS-CLIP	23824327
MIRT611990	hsa-miR-335-3p	HITS-CLIP	23824327
MIRT611991	hsa-miR-5096	HITS-CLIP	23824327
MIRT611990	hsa-miR-335-3p	HITS-CLIP	23824327
MIRT626826	hsa-miR-6083	HITS-CLIP	23824327
MIRT611990	hsa-miR-335-3p	HITS-CLIP	23824327
MIRT654127	hsa-miR-1267	HITS-CLIP	23824327
MIRT654126	hsa-miR-367-5p	HITS-CLIP	23824327
MIRT654125	hsa-miR-6499-3p	HITS-CLIP	23824327
MIRT654124	hsa-miR-3135b	HITS-CLIP	23824327
MIRT654123	hsa-miR-504-3p	HITS-CLIP	23824327
MIRT654122	hsa-miR-122-5p	HITS-CLIP	23824327
MIRT654121	hsa-miR-3652	HITS-CLIP	23824327
MIRT654120	hsa-miR-4430	HITS-CLIP	23824327
MIRT654119	hsa-miR-3650	HITS-CLIP	23824327
MIRT654118	hsa-miR-143-5p	HITS-CLIP	23824327
MIRT654117	hsa-miR-6501-5p	HITS-CLIP	23824327
MIRT654116	hsa-miR-4423-5p	HITS-CLIP	23824327
MIRT654115	hsa-miR-744-3p	HITS-CLIP	23824327
MIRT654114	hsa-miR-5698	HITS-CLIP	23824327
MIRT654112	hsa-miR-4282	HITS-CLIP	23824327
MIRT654113	hsa-miR-526b-5p	HITS-CLIP	23824327
MIRT654111	hsa-miR-4446-5p	HITS-CLIP	23824327
MIRT626826	hsa-miR-6083	HITS-CLIP	23824327
MIRT611990	hsa-miR-335-3p	HITS-CLIP	23824327
MIRT626826	hsa-miR-6083	HITS-CLIP	23824327
MIRT611991	hsa-miR-5096	HITS-CLIP	23824327
MIRT611990	hsa-miR-335-3p	HITS-CLIP	23824327
MIRT611990	hsa-miR-335-3p	HITS-CLIP	23824327
MIRT611990	hsa-miR-335-3p	HITS-CLIP	23824327
MIRT626826	hsa-miR-6083	HITS-CLIP	23824327
MIRT611990	hsa-miR-335-3p	HITS-CLIP	23824327
MIRT611991	hsa-miR-5096	HITS-CLIP	23824327
MIRT611990	hsa-miR-335-3p	HITS-CLIP	23824327
MIRT611991	hsa-miR-5096	HITS-CLIP	23824327
MIRT611990	hsa-miR-335-3p	HITS-CLIP	23824327
MIRT611991	hsa-miR-5096	HITS-CLIP	23824327
MIRT611990	hsa-miR-335-3p	HITS-CLIP	23824327
MIRT611991	hsa-miR-5096	HITS-CLIP	23824327
MIRT611990	hsa-miR-335-3p	HITS-CLIP	23824327
MIRT534575	hsa-miR-20b-5p	PAR-CLIP	21572407
MIRT534574	hsa-miR-519d-3p	PAR-CLIP	21572407
MIRT534573	hsa-miR-20a-5p	PAR-CLIP	21572407
MIRT534572	hsa-miR-17-5p	PAR-CLIP	21572407
MIRT534571	hsa-miR-106b-5p	PAR-CLIP	21572407
MIRT534570	hsa-miR-106a-5p	PAR-CLIP	21572407
MIRT048811	hsa-miR-93-5p	PAR-CLIP	21572407
MIRT534569	hsa-miR-526b-3p	PAR-CLIP	21572407
MIRT534568	hsa-miR-5590-3p	PAR-CLIP	21572407
MIRT534567	hsa-miR-142-5p	PAR-CLIP	21572407
MIRT534566	hsa-miR-340-5p	PAR-CLIP	21572407
MIRT554613	hsa-miR-3609	PAR-CLIP	21572407
MIRT554612	hsa-miR-548ah-5p	PAR-CLIP	21572407
MIRT554611	hsa-miR-4796-3p	PAR-CLIP	21572407
MIRT554610	hsa-miR-519a-3p	PAR-CLIP	21572407
MIRT554609	hsa-miR-519b-3p	PAR-CLIP	21572407
MIRT554608	hsa-miR-519c-3p	PAR-CLIP	21572407
MIRT554607	hsa-miR-5003-3p	PAR-CLIP	21572407
MIRT534565	hsa-miR-1-5p	PAR-CLIP	21572407
MIRT554606	hsa-miR-485-3p	PAR-CLIP	21572407
MIRT554605	hsa-miR-539-3p	PAR-CLIP	21572407
MIRT546655	hsa-miR-301a-3p	PAR-CLIP	21572407
MIRT546658	hsa-miR-130b-3p	PAR-CLIP	21572407
MIRT546653	hsa-miR-301b-3p	PAR-CLIP	21572407
MIRT546656	hsa-miR-3666	PAR-CLIP	21572407
MIRT546657	hsa-miR-130a-3p	PAR-CLIP	21572407
MIRT546659	hsa-miR-4295	PAR-CLIP	21572407
MIRT546654	hsa-miR-454-3p	PAR-CLIP	21572407
MIRT546652	hsa-miR-376c-3p	PAR-CLIP	21572407
MIRT546651	hsa-miR-5586-3p	PAR-CLIP	21572407
MIRT546650	hsa-miR-6504-3p	PAR-CLIP	21572407
MIRT546649	hsa-miR-664a-3p	PAR-CLIP	21572407
MIRT546648	hsa-miR-16-2-3p	PAR-CLIP	21572407
MIRT546647	hsa-miR-195-3p	PAR-CLIP	21572407
MIRT546677	hsa-miR-548m	PAR-CLIP	21572407
MIRT546676	hsa-miR-18a-5p	PAR-CLIP	21572407
MIRT546675	hsa-miR-18b-5p	PAR-CLIP	21572407
MIRT546674	hsa-miR-4735-3p	PAR-CLIP	21572407
MIRT546673	hsa-miR-4728-3p	PAR-CLIP	21572407
MIRT546672	hsa-miR-3126-5p	PAR-CLIP	21572407
MIRT546671	hsa-miR-6875-5p	PAR-CLIP	21572407
MIRT546670	hsa-miR-4419a	PAR-CLIP	21572407
MIRT546669	hsa-miR-4510	PAR-CLIP	21572407
MIRT546668	hsa-miR-6127	PAR-CLIP	21572407
MIRT546667	hsa-miR-6129	PAR-CLIP	21572407
MIRT546666	hsa-miR-6130	PAR-CLIP	21572407
MIRT546665	hsa-miR-6133	PAR-CLIP	21572407
MIRT546663	hsa-miR-4663	PAR-CLIP	21572407
MIRT546664	hsa-miR-7160-5p	PAR-CLIP	21572407
MIRT546662	hsa-miR-8077	PAR-CLIP	21572407
MIRT546661	hsa-miR-6834-5p	PAR-CLIP	21572407
MIRT546660	hsa-miR-106a-3p	PAR-CLIP	21572407
MIRT546659	hsa-miR-4295	PAR-CLIP	21572407
MIRT546658	hsa-miR-130b-3p	PAR-CLIP	21572407
MIRT546657	hsa-miR-130a-3p	PAR-CLIP	21572407
MIRT546656	hsa-miR-3666	PAR-CLIP	21572407
MIRT546655	hsa-miR-301a-3p	PAR-CLIP	21572407
MIRT546654	hsa-miR-454-3p	PAR-CLIP	21572407
MIRT546653	hsa-miR-301b-3p	PAR-CLIP	21572407
MIRT546652	hsa-miR-376c-3p	PAR-CLIP	21572407
MIRT546651	hsa-miR-5586-3p	PAR-CLIP	21572407
MIRT546650	hsa-miR-6504-3p	PAR-CLIP	21572407
MIRT546649	hsa-miR-664a-3p	PAR-CLIP	21572407
MIRT546648	hsa-miR-16-2-3p	PAR-CLIP	21572407
MIRT546647	hsa-miR-195-3p	PAR-CLIP	21572407
MIRT534575	hsa-miR-20b-5p	PAR-CLIP	22012620
MIRT534574	hsa-miR-519d-3p	PAR-CLIP	22012620
MIRT534573	hsa-miR-20a-5p	PAR-CLIP	22012620
MIRT534572	hsa-miR-17-5p	PAR-CLIP	22012620
MIRT534571	hsa-miR-106b-5p	PAR-CLIP	22012620
MIRT534570	hsa-miR-106a-5p	PAR-CLIP	22012620
MIRT048811	hsa-miR-93-5p	PAR-CLIP	22012620
MIRT534569	hsa-miR-526b-3p	PAR-CLIP	22012620
MIRT534568	hsa-miR-5590-3p	PAR-CLIP	22012620
MIRT534567	hsa-miR-142-5p	PAR-CLIP	22012620
MIRT534566	hsa-miR-340-5p	PAR-CLIP	22012620
MIRT534565	hsa-miR-1-5p	PAR-CLIP	22012620
MIRT447726	hsa-miR-548n	PAR-CLIP	22100165
MIRT447725	hsa-miR-5088-5p	PAR-CLIP	22100165
MIRT447724	hsa-miR-4635	PAR-CLIP	22100165
MIRT447723	hsa-miR-24-3p	PAR-CLIP	22100165
MIRT447722	hsa-miR-4437	PAR-CLIP	22100165
MIRT447726	hsa-miR-548n	PAR-CLIP	22100165
MIRT447725	hsa-miR-5088-5p	PAR-CLIP	22100165
MIRT447724	hsa-miR-4635	PAR-CLIP	22100165
MIRT447723	hsa-miR-24-3p	PAR-CLIP	22100165
MIRT447722	hsa-miR-4437	PAR-CLIP	22100165
MIRT1318349	hsa-miR-1202	CLIP-seq
MIRT1318350	hsa-miR-1276	CLIP-seq
MIRT1318351	hsa-miR-128	CLIP-seq
MIRT1318352	hsa-miR-129-3p	CLIP-seq
MIRT1318353	hsa-miR-1299	CLIP-seq
MIRT1318354	hsa-miR-130a	CLIP-seq
MIRT1318355	hsa-miR-130b	CLIP-seq
MIRT1318356	hsa-miR-134	CLIP-seq
MIRT1318357	hsa-miR-148a	CLIP-seq
MIRT1318358	hsa-miR-148b	CLIP-seq
MIRT1318359	hsa-miR-152	CLIP-seq
MIRT1318360	hsa-miR-1825	CLIP-seq
MIRT1318361	hsa-miR-18a	CLIP-seq
MIRT1318362	hsa-miR-18b	CLIP-seq
MIRT1318363	hsa-miR-198	CLIP-seq
MIRT1318364	hsa-miR-199a-5p	CLIP-seq
MIRT1318365	hsa-miR-199b-5p	CLIP-seq
MIRT1318366	hsa-miR-19a	CLIP-seq
MIRT1318367	hsa-miR-19b	CLIP-seq
MIRT1318368	hsa-miR-2278	CLIP-seq
MIRT1318369	hsa-miR-27a	CLIP-seq
MIRT1318370	hsa-miR-27b	CLIP-seq
MIRT1318371	hsa-miR-301a	CLIP-seq
MIRT1318372	hsa-miR-301b	CLIP-seq
MIRT1318373	hsa-miR-3118	CLIP-seq
MIRT1318374	hsa-miR-3140-3p	CLIP-seq
MIRT1318375	hsa-miR-3143	CLIP-seq
MIRT1318376	hsa-miR-3148	CLIP-seq
MIRT1318377	hsa-miR-3164	CLIP-seq
MIRT1318378	hsa-miR-3972	CLIP-seq
MIRT1318379	hsa-miR-4269	CLIP-seq
MIRT1318380	hsa-miR-4420	CLIP-seq
MIRT1318381	hsa-miR-4514	CLIP-seq
MIRT1318382	hsa-miR-4517	CLIP-seq
MIRT1318383	hsa-miR-4519	CLIP-seq
MIRT1318384	hsa-miR-454	CLIP-seq
MIRT1318385	hsa-miR-455-5p	CLIP-seq
MIRT1318386	hsa-miR-4660	CLIP-seq
MIRT1318387	hsa-miR-4687-5p	CLIP-seq
MIRT1318388	hsa-miR-4692	CLIP-seq
MIRT1318389	hsa-miR-4742-5p	CLIP-seq
MIRT1318390	hsa-miR-4755-3p	CLIP-seq
MIRT1318391	hsa-miR-4762-5p	CLIP-seq
MIRT1318392	hsa-miR-483-3p	CLIP-seq
MIRT1318393	hsa-miR-513a-5p	CLIP-seq
MIRT1318394	hsa-miR-520f	CLIP-seq
MIRT1318395	hsa-miR-543	CLIP-seq
MIRT1318396	hsa-miR-646	CLIP-seq
MIRT1318397	hsa-miR-649	CLIP-seq
MIRT1318398	hsa-miR-802	CLIP-seq
MIRT1318399	hsa-miR-875-3p	CLIP-seq
MIRT1318400	hsa-miR-1305	CLIP-seq
MIRT1318401	hsa-miR-4698	CLIP-seq
MIRT1318402	hsa-miR-499-3p	CLIP-seq
MIRT1318403	hsa-miR-499a-3p	CLIP-seq
MIRT1318404	hsa-miR-579	CLIP-seq
MIRT1318405	hsa-miR-607	CLIP-seq
MIRT1553185	hsa-miR-103a	CLIP-seq
MIRT1553186	hsa-miR-107	CLIP-seq
MIRT1553185	hsa-miR-103a	CLIP-seq
MIRT1553186	hsa-miR-107	CLIP-seq
MIRT1318351	hsa-miR-128	CLIP-seq
MIRT1318353	hsa-miR-1299	CLIP-seq
MIRT2094679	hsa-miR-144	CLIP-seq
MIRT1318369	hsa-miR-27a	CLIP-seq
MIRT1318370	hsa-miR-27b	CLIP-seq
MIRT1318376	hsa-miR-3148	CLIP-seq
MIRT2094680	hsa-miR-3166	CLIP-seq
MIRT2094681	hsa-miR-548p	CLIP-seq
MIRT2094682	hsa-miR-578	CLIP-seq
MIRT2094683	hsa-miR-642b	CLIP-seq
MIRT1318397	hsa-miR-649	CLIP-seq
MIRT1318399	hsa-miR-875-3p	CLIP-seq
MIRT1553185	hsa-miR-103a	CLIP-seq
MIRT1553186	hsa-miR-107	CLIP-seq
MIRT1318349	hsa-miR-1202	CLIP-seq
MIRT2319138	hsa-miR-1245b-3p	CLIP-seq
MIRT1318350	hsa-miR-1276	CLIP-seq
MIRT1318351	hsa-miR-128	CLIP-seq
MIRT2319139	hsa-miR-1281	CLIP-seq
MIRT1318353	hsa-miR-1299	CLIP-seq
MIRT1318354	hsa-miR-130a	CLIP-seq
MIRT1318355	hsa-miR-130b	CLIP-seq
MIRT2094679	hsa-miR-144	CLIP-seq
MIRT1318357	hsa-miR-148a	CLIP-seq
MIRT1318358	hsa-miR-148b	CLIP-seq
MIRT1318359	hsa-miR-152	CLIP-seq
MIRT1318360	hsa-miR-1825	CLIP-seq
MIRT2319140	hsa-miR-1827	CLIP-seq
MIRT1318363	hsa-miR-198	CLIP-seq
MIRT1318364	hsa-miR-199a-5p	CLIP-seq
MIRT1318365	hsa-miR-199b-5p	CLIP-seq
MIRT1318366	hsa-miR-19a	CLIP-seq
MIRT1318367	hsa-miR-19b	CLIP-seq
MIRT2319141	hsa-miR-21	CLIP-seq
MIRT1318368	hsa-miR-2278	CLIP-seq
MIRT1318369	hsa-miR-27a	CLIP-seq
MIRT1318370	hsa-miR-27b	CLIP-seq
MIRT1318371	hsa-miR-301a	CLIP-seq
MIRT1318372	hsa-miR-301b	CLIP-seq
MIRT2319142	hsa-miR-3134	CLIP-seq
MIRT1318374	hsa-miR-3140-3p	CLIP-seq
MIRT1318375	hsa-miR-3143	CLIP-seq
MIRT2094680	hsa-miR-3166	CLIP-seq
MIRT2319143	hsa-miR-3612	CLIP-seq
MIRT1318378	hsa-miR-3972	CLIP-seq
MIRT2319144	hsa-miR-4261	CLIP-seq
MIRT2319145	hsa-miR-4266	CLIP-seq
MIRT1318379	hsa-miR-4269	CLIP-seq
MIRT2319146	hsa-miR-4330	CLIP-seq
MIRT2319147	hsa-miR-4422	CLIP-seq
MIRT1318381	hsa-miR-4514	CLIP-seq
MIRT1318382	hsa-miR-4517	CLIP-seq
MIRT1318383	hsa-miR-4519	CLIP-seq
MIRT1318384	hsa-miR-454	CLIP-seq
MIRT1318385	hsa-miR-455-5p	CLIP-seq
MIRT2319148	hsa-miR-4643	CLIP-seq
MIRT2319149	hsa-miR-466	CLIP-seq
MIRT1318386	hsa-miR-4660	CLIP-seq
MIRT2319150	hsa-miR-4681	CLIP-seq
MIRT1318388	hsa-miR-4692	CLIP-seq
MIRT2319151	hsa-miR-4695-5p	CLIP-seq
MIRT1318389	hsa-miR-4742-5p	CLIP-seq
MIRT1318390	hsa-miR-4755-3p	CLIP-seq
MIRT1318391	hsa-miR-4762-5p	CLIP-seq
MIRT2319152	hsa-miR-4779	CLIP-seq
MIRT2319153	hsa-miR-4786-5p	CLIP-seq
MIRT2319154	hsa-miR-4789-3p	CLIP-seq
MIRT2319155	hsa-miR-494	CLIP-seq
MIRT1318393	hsa-miR-513a-5p	CLIP-seq
MIRT1318394	hsa-miR-520f	CLIP-seq
MIRT1318395	hsa-miR-543	CLIP-seq
MIRT2319156	hsa-miR-548ac	CLIP-seq
MIRT2319157	hsa-miR-548ae	CLIP-seq
MIRT2319158	hsa-miR-548aj	CLIP-seq
MIRT2319159	hsa-miR-548am	CLIP-seq
MIRT2319160	hsa-miR-548d-3p	CLIP-seq
MIRT2319161	hsa-miR-548x	CLIP-seq
MIRT2319162	hsa-miR-548z	CLIP-seq
MIRT2094682	hsa-miR-578	CLIP-seq
MIRT2319163	hsa-miR-590-5p	CLIP-seq
MIRT1318396	hsa-miR-646	CLIP-seq
MIRT2319164	hsa-miR-650	CLIP-seq
MIRT2319165	hsa-miR-769-5p	CLIP-seq
MIRT1318398	hsa-miR-802	CLIP-seq
MIRT1318399	hsa-miR-875-3p	CLIP-seq
MIRT1553185	hsa-miR-103a	CLIP-seq
MIRT1553186	hsa-miR-107	CLIP-seq
MIRT1318379	hsa-miR-4269	CLIP-seq
MIRT1318381	hsa-miR-4514	CLIP-seq
MIRT1318388	hsa-miR-4692	CLIP-seq
MIRT1318389	hsa-miR-4742-5p	CLIP-seq
MIRT2614757	hsa-miR-1	CLIP-seq
MIRT2614758	hsa-miR-1224-5p	CLIP-seq
MIRT2614759	hsa-miR-1294	CLIP-seq
MIRT2614760	hsa-miR-153	CLIP-seq
MIRT2614761	hsa-miR-206	CLIP-seq
MIRT2614762	hsa-miR-3125	CLIP-seq
MIRT2614763	hsa-miR-3189-5p	CLIP-seq
MIRT2614764	hsa-miR-3916	CLIP-seq
MIRT2614765	hsa-miR-3973	CLIP-seq
MIRT2614766	hsa-miR-425	CLIP-seq
MIRT2614767	hsa-miR-4316	CLIP-seq
MIRT2614768	hsa-miR-4684-3p	CLIP-seq
MIRT2614769	hsa-miR-4751	CLIP-seq
MIRT2614770	hsa-miR-4758-3p	CLIP-seq
MIRT2614771	hsa-miR-520d-5p	CLIP-seq
MIRT2614772	hsa-miR-524-5p	CLIP-seq
MIRT2614773	hsa-miR-613	CLIP-seq
MIRT2094683	hsa-miR-642b	CLIP-seq

Show/Hide all (51)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000166	Function	Nucleotide binding	IEA
GO:0000287	Function	Magnesium ion binding	IEA
GO:0001818	Process	Negative regulation of cytokine production	IEA
GO:0001818	Process	Negative regulation of cytokine production	TAS	18508628
GO:0004672	Function	Protein kinase activity	IEA
GO:0004674	Function	Protein serine/threonine kinase activity	IBA
GO:0004674	Function	Protein serine/threonine kinase activity	IDA	9687510, 9873047
GO:0004674	Function	Protein serine/threonine kinase activity	IEA
GO:0004674	Function	Protein serine/threonine kinase activity	TAS
GO:0004713	Function	Protein tyrosine kinase activity	IDA	9873047
GO:0005515	Function	Protein binding	IPI	20936779, 21988832, 25535969, 32296183, 32707033, 33961781
GO:0005524	Function	ATP binding	IDA	9687510
GO:0005524	Function	ATP binding	IEA
GO:0005634	Component	Nucleus	IDA	9687510, 18511904
GO:0005634	Component	Nucleus	IEA
GO:0005634	Component	Nucleus	IMP	12628924
GO:0005654	Component	Nucleoplasm	IBA
GO:0005654	Component	Nucleoplasm	IDA
GO:0005654	Component	Nucleoplasm	TAS
GO:0005737	Component	Cytoplasm	IBA
GO:0005737	Component	Cytoplasm	IDA	18511904
GO:0005737	Component	Cytoplasm	IEA
GO:0006338	Process	Chromatin remodeling	IEA
GO:0006355	Process	Regulation of DNA-templated transcription	IBA
GO:0006355	Process	Regulation of DNA-templated transcription	IDA	9687510
GO:0006355	Process	Regulation of DNA-templated transcription	IEA
GO:0006355	Process	Regulation of DNA-templated transcription	IMP	12763138
GO:0006468	Process	Protein phosphorylation	IDA	9687510
GO:0006954	Process	Inflammatory response	IEA
GO:0007411	Process	Axon guidance	TAS
GO:0016301	Function	Kinase activity	IEA
GO:0016740	Function	Transferase activity	IEA
GO:0032793	Process	Positive regulation of CREB transcription factor activity	TAS	18508628
GO:0035175	Function	Histone H3S10 kinase activity	IEA
GO:0035175	Function	Histone H3S10 kinase activity	IMP	12773393
GO:0035556	Process	Intracellular signal transduction	IDA	9687510
GO:0035556	Process	Intracellular signal transduction	IEA
GO:0038202	Process	TORC1 signaling	IBA
GO:0043687	Process	Post-translational protein modification	IDA	15010469
GO:0043687	Process	Post-translational protein modification	IMP	12773393
GO:0044022	Function	Histone H3S28 kinase activity	IEA
GO:0044022	Function	Histone H3S28 kinase activity	IMP	12773393
GO:0044024	Function	Histone H2AS1 kinase activity	IDA	15010469
GO:0045892	Process	Negative regulation of DNA-templated transcription	IDA	15010469
GO:0045944	Process	Positive regulation of transcription by RNA polymerase II	IMP	20018936
GO:0046872	Function	Metal ion binding	IEA
GO:0051092	Process	Positive regulation of NF-kappaB transcription factor activity	IMP	12628924, 18511904
GO:0070498	Process	Interleukin-1-mediated signaling pathway	IEA
GO:0070498	Process	Interleukin-1-mediated signaling pathway	IMP	20018936
GO:0099175	Process	Regulation of postsynapse organization	IEA
GO:0106310	Function	Protein serine kinase activity	IEA

MIM	HGNC	e!Ensembl
603607	10434	ENSG00000100784

O75582

Protein name

Ribosomal protein S6 kinase alpha-5 (S6K-alpha-5) (EC 2.7.11.1) (90 kDa ribosomal protein S6 kinase 5) (Nuclear mitogen- and stress-activated protein kinase 1) (RSK-like protein kinase) (RSKL)

Protein function

Serine/threonine-protein kinase that is required for the mitogen or stress-induced phosphorylation of the transcription factors CREB1 and ATF1 and for the regulation of the transcription factors RELA, STAT3 and ETV1/ER81, and that contributes to

PDB

1VZO , 3KN5 , 3KN6 , 7UP4 , 7UP5 , 7UP6 , 7UP7 , 7UP8

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00069	Pkinase	49 → 318	Protein kinase domain	Domain
PF00433	Pkinase_C	339 → 377	Protein kinase C terminal domain	Family
PF00069	Pkinase	427 → 687	Protein kinase domain	Domain

Tissue specificity

TISSUE SPECIFICITY: Widely expressed with high levels in heart, brain and placenta. Less abundant in lung, kidney and liver. {ECO:0000269|PubMed:9687510, ECO:0000269|PubMed:9873047}.

Sequence

MEEEGGSSGGAAGTSADGGDGGEQLLTVKHELRTANLTGHAEKVGIENFELLKVLGTGAY
GKVFLVRKISGHDTGKLYAMKVLKKATIVQKAKTTEHTRTERQVLEHIRQSPFLVTLHYA
FQTETKLHLILDYINGGELFTHLSQRERFTEHEVQIYVGEIVLALEHLHKLGIIYRDIKL
ENILLDSNGHVVLTDFGLSKEFVADETERAYSFCGTIEYMAPDIVRGGDSGHDKAVDWWS
LGVLMYELLTGASPFTVDGEKNSQAEISRRILKSEPPYPQEMSALAKDLIQRLLMKDPKK
RLGCGPRDADEIKEHLFFQKINWDDLAAKKVPAPFKPVIRDELDVSNFAEEFTEMDPTYS
PAALPQSSEKLFQGYSFVAPSILFKRNAAVIDPLQFHMGVERPGVTNVARSAMMKDSPFY
QHYDLDLKDKPLGEGSFSICRKCVHKKSNQAFAVKIISKRMEANTQKEITALKLCEGHPN
IVKLHEVFHDQLHTFLVMELLNGGELFERIKKKKHFSETEASYIMRKLVSAVSHMHDVGV
VHRDLKPENLLFTDENDNLEIKIIDFGFARLKPPDNQPLKTPCFTLHYAAPELLNQNGYD
ESCDLWSLGVILYTMLSGQVPFQSHDRSLTCTSAVEIMKKIKKGDFSFEGEAWKNVSQEA
KDLIQGLLTVDPNKRLKMSGLRYNEWLQDGSQLSSNPLMTPDILGSSGAAVHTCVKATFH
AFNKYKREGFCLQNVDKAPLAKRRKMKKTSTSTETRSSSSESSHSSSSHSHGKTTPTKTL
QPSNPADSNNPETLFQFSDSVA

Sequence length

802

Interactions

View interactions

Evidence Score: ★☆☆☆☆ Gene-disease association found in Text Mining only ★★☆☆☆ Found in Text Mining and Unknown/Other Associations ★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Show/Hide Unknown Diseases (6)

Phenotype Name	Clinical Significance	Source	Evidence Score
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
COLOR VISION DISORDER	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
GLOMERULONEPHRITIS	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
HODGKINS LYMPHOMA	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
MAJOR DEPRESSIVE DISORDER	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
MULTIPLE SCLEROSIS	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Thyroid cancer, nonmedullary, 1	Uncertain significance	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Show/Hide Text Mining Associations (27)

Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Associations from Text Mining Disease associations identified through text mining
Actinic keratosis	Actinic keratosis	BEFREE	29298652		★★★★★ ★☆☆☆☆ Found in Text Mining only
Arthritis Psoriatic	Psoriatic arthritis	Pubtator	16543895	Stimulate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Breast Carcinoma	Breast Carcinoma	BEFREE	23604116, 29327245, 29358704, 29674681		★★★★★ ★☆☆☆☆ Found in Text Mining only
Breast Neoplasms	Breast neoplasm	Pubtator	23292247, 23675462, 27390128, 29327245	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Carcinogenesis	Carcinogenesis	Pubtator	25958199	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Chronic Obstructive Airway Disease	Chronic Obstructive Pulmonary Disease	BEFREE	22312446		★★★★★ ★☆☆☆☆ Found in Text Mining only
Colonic Neoplasms	Colonic neoplasm	Pubtator	34060286	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Colorectal Carcinoma	Colorectal Cancer	BEFREE	25776026		★★★★★ ★☆☆☆☆ Found in Text Mining only
Colorectal Neoplasms	Colorectal neoplasm	Pubtator	34060286	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Hyperglycemia	Hyperglycemia	Pubtator	36930661	Stimulate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Leiomyoma	Leiomyoma	Pubtator	27582276	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Leukemia Myeloid Acute	Myeloid leukemia	Pubtator	23474756	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant neoplasm of breast	Breast Cancer	BEFREE	23604116, 29327245, 29358704, 29674681		★★★★★ ★☆☆☆☆ Found in Text Mining only
Malignant Neoplasms	Malignant Neoplasm	BEFREE	22250664, 25958199		★★★★★ ★☆☆☆☆ Found in Text Mining only
Meningioma	Meningioma	Pubtator	32461543	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Nasopharyngeal Carcinoma	Nasopharyngeal carcinoma	Pubtator	23496845, 25958199	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Nasopharyngeal carcinoma	Nasopharyngeal Carcinoma	BEFREE	25958199		★★★★★ ★☆☆☆☆ Found in Text Mining only
Neoplasms	Neoplasms	BEFREE	23994345, 29327245		★★★★★ ★☆☆☆☆ Found in Text Mining only
Psoriasis	Psoriasis	LHGDN	16543895		★★★★★ ★☆☆☆☆ Found in Text Mining only
Psoriasis	Psoriasis	Pubtator	16543895	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Rheumatoid Arthritis	Rheumatoid arthritis	BEFREE	24792438		★★★★★ ★☆☆☆☆ Found in Text Mining only
Sjogren's Syndrome	Sjogren syndrome	Pubtator	31281310	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Spinocerebellar Ataxia Type 1	Spinocerebellar Ataxia	BEFREE	23719381		★★★★★ ★☆☆☆☆ Found in Text Mining only
Squamous cell carcinoma	Carcinoma	LHGDN	16532028		★★★★★ ★☆☆☆☆ Found in Text Mining only
Squamous Cell Carcinoma of Head and Neck	Squamous cell carcinoma	Pubtator	24192080	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Stomach Neoplasms	Stomach neoplasms	Pubtator	27588146	Associate	★★★★★ ★☆☆☆☆ Found in Text Mining only
Subarachnoid Hemorrhage	Subarachnoid hemorrhage	BEFREE	28927047		★★★★★ ★☆☆☆☆ Found in Text Mining only

RPS6KA5 (ribosomal protein S6 kinase A5)