RPRD1B (regulation of nuclear pre-mRNA domain containing 1B)
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Gene
Gene information from NCBI Gene database.
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| Entrez ID | 58490 |
| Gene name | Regulation of nuclear pre-mRNA domain containing 1B |
| Gene symbol | RPRD1B |
| Synonyms (NCBI Gene) |
C20orf77CREPTK-HKub5-HeraNET60dJ1057B20.2
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| Chromosome | 20 |
| Chromosome location | 20q11.23 |
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miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
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Other IDs
Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
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Protein
Protein information from UniProt database.
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UniProt ID
Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
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Q9NQG5 | |||||||||||||||
| Protein name | Regulation of nuclear pre-mRNA domain-containing protein 1B (Cell cycle-related and expression-elevated protein in tumor) | |||||||||||||||
| Protein function | Interacts with phosphorylated C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase II subunit POLR2A, and participates in dephosphorylation of the CTD by RPAP2. Transcriptional regulator which enhances expression of CCND1. P | |||||||||||||||
| PDB | 4FLA , 4FU3 , 4HFG , 4NAD , 4Q94 , 4Q96 , 9B9L | |||||||||||||||
| Family and domains |
Pfam
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| Tissue specificity | TISSUE SPECIFICITY: Preferentially expressed in a range of tumor tissues including colon, lung, liver, breast, prostate, stomach, uterine endometrium and cervical cancers with higher levels in tumors than in adjacent non-tumor tissue (at protein level). { | |||||||||||||||
| Sequence | ||||||||||||||||
| Sequence length | 326 | |||||||||||||||
| Interactions | View interactions | |||||||||||||||
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Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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Related Genes
Genes most often co-reported with RPRD1B across shared curated disease and pathway associations.
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Diseases Linked via Similar Genes
Diseases curated for genes most similar to RPRD1B (see Related Genes above), that are NOT already directly curated for RPRD1B itself -- a lead worth checking, not a confirmed association.
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