RPRD1A (regulation of nuclear pre-mRNA domain containing 1A)
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Gene
Gene information from NCBI Gene database.
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| Entrez ID | 55197 |
| Gene name | Regulation of nuclear pre-mRNA domain containing 1A |
| Gene symbol | RPRD1A |
| Synonyms (NCBI Gene) |
HsT3101P15RS
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| Chromosome | 18 |
| Chromosome location | 18q12.2 |
| Summary | This gene encodes a cell-cycle and transcription regulatory protein. The encoded protein interacts with the cell cycle inhibitor cyclin-dependent kinase 4 inhibitor B and may function as a negative regulator of G(1)/S phase progression. This protein also |
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miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
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Other IDs
Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
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Protein
Protein information from UniProt database.
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UniProt ID
Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
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Q96P16 | |||||||||||||||
| Protein name | Regulation of nuclear pre-mRNA domain-containing protein 1A (Cyclin-dependent kinase inhibitor 2B-related protein) (p15INK4B-related protein) | |||||||||||||||
| Protein function | Interacts with phosphorylated C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase II subunit POLR2A, and participates in dephosphorylation of the CTD by RPAP2. May act as a negative regulator of cyclin-D1 (CCND1) and cyclin | |||||||||||||||
| PDB | 4JXT , 4NAC | |||||||||||||||
| Family and domains |
Pfam
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| Sequence | ||||||||||||||||
| Sequence length | 312 | |||||||||||||||
| Interactions | View interactions | |||||||||||||||
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Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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Related Genes
Genes most often co-reported with RPRD1A across shared curated disease and pathway associations.
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Diseases Linked via Similar Genes
Diseases curated for genes most similar to RPRD1A (see Related Genes above), that are NOT already directly curated for RPRD1A itself -- a lead worth checking, not a confirmed association.
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