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Gene Gene information from NCBI Gene database.
Entrez ID 55197
Gene name Regulation of nuclear pre-mRNA domain containing 1A
Gene symbol RPRD1A
Synonyms (NCBI Gene)
HsT3101P15RS
Chromosome 18
Chromosome location 18q12.2
Summary This gene encodes a cell-cycle and transcription regulatory protein. The encoded protein interacts with the cell cycle inhibitor cyclin-dependent kinase 4 inhibitor B and may function as a negative regulator of G(1)/S phase progression. This protein also
miRNA miRNA information provided by mirtarbase database.
537 Show/Hide all (537)
miRTarBase ID miRNA Experiments Reference
MIRT020628 hsa-miR-155-5p Proteomics 18668040
MIRT028472 hsa-miR-30a-5p Proteomics 18668040
MIRT050478 hsa-miR-20a-5p CLASH 23622248
MIRT047673 hsa-miR-10a-5p CLASH 23622248
MIRT047242 hsa-miR-181b-5p CLASH 23622248
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
14 Show/Hide all (14)
GO ID Ontology Definition Evidence Reference
GO:0000993 Function RNA polymerase II complex binding IBA
GO:0001111 Process RNA polymerase II promoter clearance IEA
GO:0001111 Process RNA polymerase II promoter clearance IMP 22231121
GO:0005515 Function Protein binding IPI 24981860, 24997600, 25416956, 28514442, 32296183, 33961781
GO:0005634 Component Nucleus IDA 22231121
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
610347 25560 ENSG00000141425
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q96P16
Protein name Regulation of nuclear pre-mRNA domain-containing protein 1A (Cyclin-dependent kinase inhibitor 2B-related protein) (p15INK4B-related protein)
Protein function Interacts with phosphorylated C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase II subunit POLR2A, and participates in dephosphorylation of the CTD by RPAP2. May act as a negative regulator of cyclin-D1 (CCND1) and cyclin
PDB 4JXT , 4NAC
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF16566 CREPT 164 → 310 Cell-cycle alteration and expression-elevated protein in tumour Domain
PF04818 CID 7 → 125 CID domain Domain
Sequence
Sequence length 312
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
Reactome Pathway
RNA polymerase II transcribes snRNA genes