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Gene Gene information from NCBI Gene database.
Entrez ID 79102
Gene name Ring finger protein 26
Gene symbol RNF26
Synonyms (NCBI Gene)
-
Chromosome 11
Chromosome location 11q23.3
Summary The protein encoded by this intronless gene contains a C3HC5 type of RING finger, a motif known to be involved in protein-DNA and protein-protein interactions. The expression of this gene was found to be upregulated in cancer cell lines derived from diffe
miRNA miRNA information provided by mirtarbase database.
306 Show/Hide all (306)
miRTarBase ID miRNA Experiments Reference
MIRT024944 hsa-miR-215-5p Microarray 19074876
MIRT026179 hsa-miR-192-5p Microarray 19074876
MIRT051481 hsa-let-7e-5p CLASH 23622248
MIRT043248 hsa-miR-324-5p CLASH 23622248
MIRT036664 hsa-miR-935 CLASH 23622248
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
22 Show/Hide all (22)
GO ID Ontology Definition Evidence Reference
GO:0005515 Function Protein binding IPI 21750715, 27368102, 38890443
GO:0005783 Component Endoplasmic reticulum IEA
GO:0005789 Component Endoplasmic reticulum membrane IDA 33472082
GO:0005789 Component Endoplasmic reticulum membrane IDA 25254379, 27368102
GO:0005789 Component Endoplasmic reticulum membrane IEA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
606130 14646 ENSG00000173456
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q9BY78
Protein name E3 ubiquitin-protein ligase RNF26 (EC 2.3.2.27) (RING finger protein 26)
Protein function E3 ubiquitin-protein ligase that plays a key role in endosome organization by retaining vesicles in the perinuclear cloud (PubMed:27368102). Acts as a platform for perinuclear positioning of the endosomal system by mediating ubiquitination of SQ
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF13920 zf-C3HC4_3 376 → 428 Domain
Tissue specificity TISSUE SPECIFICITY: Ubiquitous. Up-regulated in several cancer cell lines. {ECO:0000269|PubMed:11352657}.
Sequence
MEAVYLVVNGLGLVLDVLTLVLDLNFLLVSSLLASLAWLLAFVYNLPHTVLTSLLHLGRG
VLLSLLALIEAVVRFTCGGLQALCTLLYSCCSGLESLKLLGHLASHGALRSREILHRGVL
NVVSSGHALLRQACDICAIAMSLVAYVINSLVNICLIGTQNLFSLVLALWDAVTGPLWRM
TDVVAAFLAHISSSAVAMAILLWTPCQLALELLASAARLLASFVLVNLTGLVLLACVLAV
TVTVLHPDFTLRLATQALSQLHARPSYHRLREDVMRLSRLALGSEAWRRVWSRSLQLASW
PNRGGAPGAPQGDPMRVFSVRTRRQDTLPEAGRRSEAEEEEARTIRVTPVRGRERLNEEE
PPGGQDPWKLLKEQEERKKCVICQDQSKTVLLLPCRHLCLCQACTEILMRHPVYHRNCPL
CRRGILQT
LNVYL
Sequence length 433
Interactions View interactions