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Gene Gene information from NCBI Gene database.
Entrez ID 26994
Gene name Ring finger protein 11
Gene symbol RNF11
Synonyms (NCBI Gene)
CGI-123SID1669
Chromosome 1
Chromosome location 1p32.3
Summary The protein encoded by this gene contains a RING-H2 finger motif, which is known to be important for protein-protein interactions. The expression of this gene has been shown to be induced by mutant RET proteins (MEN2A/MEN2B). The germline mutations in RET
miRNA miRNA information provided by mirtarbase database.
1026 Show/Hide all (1026)
miRTarBase ID miRNA Experiments Reference
MIRT019648 hsa-miR-340-5p Sequencing 20371350
MIRT030623 hsa-miR-24-3p Sequencing 20371350
MIRT031075 hsa-miR-21-5p Microarray 20048743
MIRT031075 hsa-miR-21-5p Microarray 18591254
MIRT031299 hsa-miR-19b-3p Sequencing 20371350
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
21 Show/Hide all (21)
GO ID Ontology Definition Evidence Reference
GO:0000151 Component Ubiquitin ligase complex IBA
GO:0000151 Component Ubiquitin ligase complex IDA 14755250
GO:0000151 Component Ubiquitin ligase complex IEA
GO:0003677 Function DNA binding TAS 10673045
GO:0005515 Function Protein binding IPI 14755250, 15231748, 19131965, 19549727, 19690564, 20676133, 21516116, 21988832, 28514442, 31515488, 32296183, 32814053, 33961781, 35044719, 37100772, 37219487
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
612598 10056 ENSG00000123091
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q9Y3C5
Protein name RING finger protein 11
Protein function Essential component of a ubiquitin-editing protein complex, comprising also TNFAIP3, ITCH and TAX1BP1, that ensures the transient nature of inflammatory signaling pathways. Promotes the association of TNFAIP3 to RIPK1 after TNF stimulation. TNFA
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF13639 zf-RING_2 97 → 140 Ring finger domain Domain
Tissue specificity TISSUE SPECIFICITY: Expressed at low levels in the lung, liver, kidney, pancreas, spleen, prostate, thymus, ovary, small intestine, colon, and peripheral blood lymphocytes, and, at intermediate levels, in the testis, heart, brain and placenta. Highest exp
Sequence
MGNCLKSPTSDDISLLHESQSDRASFGEGTEPDQEPPPPYQEQVPVPVYHPTPSQTRLAT
QLTEEEQIRIAQRIGLIQHLPKGVYDPGRDGSEKKIRECVICMMDFVYGDPIRFLPCMHI
YHLDCIDDWLMRSFTCPSCM
EPVDAALLSSYETN
Sequence length 154
Interactions View interactions