RNASEK (ribonuclease K)

Download as csv Download as pdf

Log in to save this analysis

Save This Analysis

Title Project / Tag (optional) Note (optional)

Cancel Save

On this page

Gene miRNA Gene ontology Other IDs Protein Related genes Diseases linked via similar genes

Gene

• Entrez ID: 440400
• Gene name: Ribonuclease K
• Gene symbol: RNASEK
• Synonyms (NCBI Gene): -
• Chromosome: 17
• Chromosome location: 17p13.1

miRNA Show/Hide all (139)

miRTarBase ID	miRNA	Experiments	Reference
MIRT039109	hsa-miR-769-3p	CLASH	23622248
MIRT037802	hsa-miR-92b-5p	CLASH	23622248
MIRT037392	hsa-miR-744-5p	CLASH	23622248
MIRT037346	hsa-miR-877-5p	CLASH	23622248
MIRT486219	hsa-miR-3661	PAR-CLIP	23592263
MIRT486218	hsa-miR-631	PAR-CLIP	23592263
MIRT486217	hsa-miR-3195	PAR-CLIP	23592263
MIRT486216	hsa-miR-6809-5p	PAR-CLIP	23592263
MIRT037802	hsa-miR-92b-5p	PAR-CLIP	23592263
MIRT486215	hsa-miR-6756-5p	PAR-CLIP	23592263
MIRT486213	hsa-miR-6766-5p	PAR-CLIP	23592263
MIRT486214	hsa-miR-4648	PAR-CLIP	23592263
MIRT486219	hsa-miR-3661	PAR-CLIP	23592263
MIRT486218	hsa-miR-631	PAR-CLIP	23592263
MIRT486217	hsa-miR-3195	PAR-CLIP	23592263
MIRT486216	hsa-miR-6809-5p	PAR-CLIP	23592263
MIRT037802	hsa-miR-92b-5p	PAR-CLIP	23592263
MIRT486215	hsa-miR-6756-5p	PAR-CLIP	23592263
MIRT486213	hsa-miR-6766-5p	PAR-CLIP	23592263
MIRT486214	hsa-miR-4648	PAR-CLIP	23592263
MIRT1308765	hsa-miR-1273f	CLIP-seq
MIRT1308766	hsa-miR-191	CLIP-seq
MIRT1308767	hsa-miR-2278	CLIP-seq
MIRT1308768	hsa-miR-2467-3p	CLIP-seq
MIRT1308769	hsa-miR-3130-5p	CLIP-seq
MIRT1308770	hsa-miR-3154	CLIP-seq
MIRT1308771	hsa-miR-361-3p	CLIP-seq
MIRT1308772	hsa-miR-3615	CLIP-seq
MIRT1308773	hsa-miR-3943	CLIP-seq
MIRT1308774	hsa-miR-4434	CLIP-seq
MIRT1308775	hsa-miR-4461	CLIP-seq
MIRT1308776	hsa-miR-4468	CLIP-seq
MIRT1308777	hsa-miR-4482	CLIP-seq
MIRT1308778	hsa-miR-4516	CLIP-seq
MIRT1308779	hsa-miR-4531	CLIP-seq
MIRT1308780	hsa-miR-4687-5p	CLIP-seq
MIRT1308781	hsa-miR-4690-3p	CLIP-seq
MIRT1308782	hsa-miR-4709-3p	CLIP-seq
MIRT1308783	hsa-miR-4743	CLIP-seq
MIRT1308784	hsa-miR-4753-3p	CLIP-seq
MIRT1308785	hsa-miR-4756-3p	CLIP-seq
MIRT1308786	hsa-miR-622	CLIP-seq
MIRT1308771	hsa-miR-361-3p	CLIP-seq
MIRT1308773	hsa-miR-3943	CLIP-seq
MIRT1308780	hsa-miR-4687-5p	CLIP-seq
MIRT1308781	hsa-miR-4690-3p	CLIP-seq
MIRT1308783	hsa-miR-4743	CLIP-seq
MIRT1308765	hsa-miR-1273f	CLIP-seq
MIRT2091605	hsa-miR-1909	CLIP-seq
MIRT1308766	hsa-miR-191	CLIP-seq
MIRT2091606	hsa-miR-3121-3p	CLIP-seq
MIRT1308769	hsa-miR-3130-5p	CLIP-seq
MIRT1308770	hsa-miR-3154	CLIP-seq
MIRT1308771	hsa-miR-361-3p	CLIP-seq
MIRT1308772	hsa-miR-3615	CLIP-seq
MIRT1308773	hsa-miR-3943	CLIP-seq
MIRT2091607	hsa-miR-4270	CLIP-seq
MIRT2091608	hsa-miR-4294	CLIP-seq
MIRT1308774	hsa-miR-4434	CLIP-seq
MIRT2091609	hsa-miR-4441	CLIP-seq
MIRT2091610	hsa-miR-4462	CLIP-seq
MIRT1308777	hsa-miR-4482	CLIP-seq
MIRT1308778	hsa-miR-4516	CLIP-seq
MIRT1308780	hsa-miR-4687-5p	CLIP-seq
MIRT1308781	hsa-miR-4690-3p	CLIP-seq
MIRT1308783	hsa-miR-4743	CLIP-seq
MIRT1308785	hsa-miR-4756-3p	CLIP-seq
MIRT1308786	hsa-miR-622	CLIP-seq
MIRT2091611	hsa-miR-924	CLIP-seq
MIRT2316205	hsa-miR-1262	CLIP-seq
MIRT2091605	hsa-miR-1909	CLIP-seq
MIRT1308768	hsa-miR-2467-3p	CLIP-seq
MIRT2091606	hsa-miR-3121-3p	CLIP-seq
MIRT1308771	hsa-miR-361-3p	CLIP-seq
MIRT1308773	hsa-miR-3943	CLIP-seq
MIRT2091607	hsa-miR-4270	CLIP-seq
MIRT2091608	hsa-miR-4294	CLIP-seq
MIRT2091609	hsa-miR-4441	CLIP-seq
MIRT1308775	hsa-miR-4461	CLIP-seq
MIRT2091610	hsa-miR-4462	CLIP-seq
MIRT2316206	hsa-miR-4681	CLIP-seq
MIRT1308780	hsa-miR-4687-5p	CLIP-seq
MIRT1308781	hsa-miR-4690-3p	CLIP-seq
MIRT2316207	hsa-miR-4701-3p	CLIP-seq
MIRT1308783	hsa-miR-4743	CLIP-seq
MIRT2091611	hsa-miR-924	CLIP-seq
MIRT2091605	hsa-miR-1909	CLIP-seq
MIRT2091606	hsa-miR-3121-3p	CLIP-seq
MIRT2091607	hsa-miR-4270	CLIP-seq
MIRT2091608	hsa-miR-4294	CLIP-seq
MIRT2091609	hsa-miR-4441	CLIP-seq
MIRT2091610	hsa-miR-4462	CLIP-seq
MIRT2091611	hsa-miR-924	CLIP-seq
MIRT2091605	hsa-miR-1909	CLIP-seq
MIRT2091606	hsa-miR-3121-3p	CLIP-seq
MIRT2612285	hsa-miR-3125	CLIP-seq
MIRT2612286	hsa-miR-3135b	CLIP-seq
MIRT2612287	hsa-miR-3184	CLIP-seq
MIRT2612288	hsa-miR-3652	CLIP-seq
MIRT2612289	hsa-miR-3916	CLIP-seq
MIRT2612290	hsa-miR-423-5p	CLIP-seq
MIRT2091607	hsa-miR-4270	CLIP-seq
MIRT2091608	hsa-miR-4294	CLIP-seq
MIRT2612291	hsa-miR-4430	CLIP-seq
MIRT2091609	hsa-miR-4441	CLIP-seq
MIRT2091610	hsa-miR-4462	CLIP-seq
MIRT2612292	hsa-miR-4492	CLIP-seq
MIRT2612293	hsa-miR-4498	CLIP-seq
MIRT2612294	hsa-miR-4706	CLIP-seq
MIRT2612295	hsa-miR-4749-5p	CLIP-seq
MIRT2612296	hsa-miR-4779	CLIP-seq
MIRT2612297	hsa-miR-4781-5p	CLIP-seq
MIRT2612298	hsa-miR-523	CLIP-seq
MIRT2612299	hsa-miR-762	CLIP-seq
MIRT2612300	hsa-miR-877	CLIP-seq
MIRT2091611	hsa-miR-924	CLIP-seq
MIRT2091605	hsa-miR-1909	CLIP-seq
MIRT2091606	hsa-miR-3121-3p	CLIP-seq
MIRT2612285	hsa-miR-3125	CLIP-seq
MIRT2612286	hsa-miR-3135b	CLIP-seq
MIRT2612287	hsa-miR-3184	CLIP-seq
MIRT2612288	hsa-miR-3652	CLIP-seq
MIRT2612289	hsa-miR-3916	CLIP-seq
MIRT2612290	hsa-miR-423-5p	CLIP-seq
MIRT2091607	hsa-miR-4270	CLIP-seq
MIRT2091608	hsa-miR-4294	CLIP-seq
MIRT2612291	hsa-miR-4430	CLIP-seq
MIRT2091609	hsa-miR-4441	CLIP-seq
MIRT2091610	hsa-miR-4462	CLIP-seq
MIRT2612292	hsa-miR-4492	CLIP-seq
MIRT2612293	hsa-miR-4498	CLIP-seq
MIRT2612294	hsa-miR-4706	CLIP-seq
MIRT2612295	hsa-miR-4749-5p	CLIP-seq
MIRT2612296	hsa-miR-4779	CLIP-seq
MIRT2612297	hsa-miR-4781-5p	CLIP-seq
MIRT2612298	hsa-miR-523	CLIP-seq
MIRT2612299	hsa-miR-762	CLIP-seq
MIRT2612300	hsa-miR-877	CLIP-seq
MIRT2091611	hsa-miR-924	CLIP-seq

Gene ontology (GO) Show/Hide all (31)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000139	Component	Golgi membrane	NAS	32001091
GO:0000220	Component	Vacuolar proton-transporting V-type ATPase, V0 domain	ISS
GO:0004518	Function	Nuclease activity	IEA
GO:0004519	Function	Endonuclease activity	IEA
GO:0004521	Function	RNA endonuclease activity	IBA
GO:0004521	Function	RNA endonuclease activity	IDA	17881363
GO:0004521	Function	RNA endonuclease activity	IEA
GO:0005515	Function	Protein binding	IPI	32296183
GO:0005765	Component	Lysosomal membrane	NAS	32001091
GO:0005886	Component	Plasma membrane	NAS	32001091
GO:0006811	Process	Monoatomic ion transport	IEA
GO:0006897	Process	Endocytosis	IEA
GO:0006898	Process	Receptor-mediated endocytosis	IMP	26212330
GO:0007035	Process	Vacuolar acidification	NAS	32001091
GO:0007042	Process	Lysosomal lumen acidification	NAS	32001091, 33065002
GO:0010008	Component	Endosome membrane	NAS	32001091
GO:0012505	Component	Endomembrane system	IEA
GO:0016020	Component	Membrane	IDA	33065002
GO:0016020	Component	Membrane	IEA
GO:0016787	Function	Hydrolase activity	IEA
GO:0019065	Process	Receptor-mediated endocytosis of virus by host cell	IMP	26212330
GO:0030665	Component	Clathrin-coated vesicle membrane	IEA
GO:0031410	Component	Cytoplasmic vesicle	IEA
GO:0033176	Component	Proton-transporting V-type ATPase complex	NAS	33065002
GO:0048388	Process	Endosomal lumen acidification	IPI	26212330
GO:0048388	Process	Endosomal lumen acidification	NAS	32001091
GO:0051452	Process	Intracellular pH reduction	NAS	32001091
GO:0061795	Process	Golgi lumen acidification	NAS	32001091
GO:1902600	Process	Proton transmembrane transport	IEA
GO:1902600	Process	Proton transmembrane transport	IPI	26212330
GO:1902600	Process	Proton transmembrane transport	NAS	33065002

Other IDs

• MIM: 617098
• HGNC: 33911
• e!Ensembl: ENSG00000219200

Protein

• UniProt ID: Q6P5S7
• Protein name: Ribonuclease kappa (RNase K) (RNase kappa) (EC 3.1.-.-) (V-type proton ATPase subunit f) (V-ATPase subunit f)
• Protein function: Endoribonuclease which preferentially cleaves ApU and ApG phosphodiester bonds. Hydrolyzes UpU bonds at a lower rate (PubMed:17881363). Regulates the activity of vacuolar (H+)-ATPase (V-ATPase) which is responsible for acidifying and maintaining
• PDB: 6WLW , 6WM2 , 6WM3 , 6WM4 , 7U4T , 7UNF
• Tissue specificity: TISSUE SPECIFICITY: Widely expressed. {ECO:0000269|PubMed:17881363}.
• Sequence:

  MGWLRPGPRPLCPPARASWAFSHRFPSPLAPRRSPTPFFMASLLCCGPKLAACGIVLSAW
  GVIMLIMLGIFFNVHSAVLIEDVPFTEKDFENGPQNIYNLYEQVSYNCFIAAGLYLLLGG
  FSFCQVRLNKRKEYMVR

• Sequence length: 137

Related Genes

No strongly related genes found yet for RNASEK.

Diseases Linked via Similar Genes

No additional diseases found yet through genes similar to RNASEK.