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Gene Gene information from NCBI Gene database.
Entrez ID 84934
Gene name RBPJ interacting and tubulin associated 1
Gene symbol RITA1
Synonyms (NCBI Gene)
C12orf52RITA
Chromosome 12
Chromosome location 12q24.13
miRNA miRNA information provided by mirtarbase database.
204 Show/Hide all (204)
miRTarBase ID miRNA Experiments Reference
MIRT740701 hsa-miR-3609 HITS-CLIP 22927820
MIRT740702 hsa-miR-548ah-5p HITS-CLIP 22927820
MIRT740703 hsa-miR-106a-5p HITS-CLIP 22927820
MIRT740704 hsa-miR-106b-5p HITS-CLIP 22927820
MIRT740705 hsa-miR-17-5p HITS-CLIP 22927820
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
23 Show/Hide all (23)
GO ID Ontology Definition Evidence Reference
GO:0000122 Process Negative regulation of transcription by RNA polymerase II TAS 21102556
GO:0005515 Function Protein binding IPI 21102556, 21516116, 25416956, 25609649, 31515488, 33961781
GO:0005634 Component Nucleus IBA
GO:0005634 Component Nucleus IDA 21102556
GO:0005634 Component Nucleus IEA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
620696 25925 ENSG00000139405
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q96K30
Protein name RBPJ-interacting and tubulin-associated protein 1 (RBPJ-interacting and tubulin-associated protein)
Protein function Tubulin-binding protein that acts as a negative regulator of Notch signaling pathway. Shuttles between the cytoplasm and the nucleus and mediates the nuclear export of RBPJ/RBPSUH, thereby preventing the interaction between RBPJ/RBPSUH and NICD
PDB 5EG6
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF17066 RITA 2 → 269 RBPJ-interacting and tubulin associated protein Family
Sequence
Sequence length 269
Interactions View interactions