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Gene Gene information from NCBI Gene database.
Entrez ID 126432
Gene name Ras and Rab interactor like
Gene symbol RINL
Synonyms (NCBI Gene)
-
Chromosome 19
Chromosome location 19q13.2
miRNA miRNA information provided by mirtarbase database.
357 Show/Hide all (357)
miRTarBase ID miRNA Experiments Reference
MIRT1307328 hsa-miR-122 CLIP-seq
MIRT1307329 hsa-miR-1224-3p CLIP-seq
MIRT1307330 hsa-miR-125a-3p CLIP-seq
MIRT1307331 hsa-miR-1260 CLIP-seq
MIRT1307332 hsa-miR-1260b CLIP-seq
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
17 Show/Hide all (17)
GO ID Ontology Definition Evidence Reference
GO:0001726 Component Ruffle IEA
GO:0001726 Component Ruffle ISS
GO:0005085 Function Guanyl-nucleotide exchange factor activity IBA
GO:0005085 Function Guanyl-nucleotide exchange factor activity IEA
GO:0005085 Function Guanyl-nucleotide exchange factor activity ISS
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
620678 24795 ENSG00000187994
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q6ZS11
Protein name Ras and Rab interactor-like protein
Protein function Guanine nucleotide exchange factor (GEF) for RAB5A and RAB22A that activates RAB5A and RAB22A by exchanging bound GDP for free GTP. Plays a role in endocytosis via its role in activating Rab family members (By similarity).
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF02204 VPS9 407 → 511 Vacuolar sorting protein 9 (VPS9) domain Family
Sequence
MAQPEDKAPEVPTEGVRLVPPQVNKADRTPLGVLSTLEPLTRLQRTWGVWHVPELDTQDA
EALVGLWPLGSFLVTGRDPSQALVLRSGPLPGEVNTYQIQKIPRGVSLESSNLCMPDLPH
LLAFLSASRDVLPRTLLLPPPTLGPRDEHTDPVQIGRVQQDTPGKVLSIVNQLYLETHRG
WGREQTPQETEPEAAQRHDPAPRNPAPHGVSWVKGPLSPEVDHPGPALASLLEEEEEDLE
GKEEGREDDPEEEGPEDVLTIHVQSLVRARSSYVARQYRSLRVRIASDSGGPHGSGDPAT
ELLQDVRHLLTDLQDHLAKDSYIRAVFGSRGPGLPKKDEDPGPALETAVCQAVLAPLKPA
LWTRLRTLRAPELRRLRRRQTALRAGAGPPGAQGPGPEGQSPAPALRSRIHERLAHLHAA
CAPRRKVALLLEVCRDVYAGLARGENQDPLGADAFLPALTEELIWSPDIGDTQLDVEFLM
ELLDPDELRGEAGYYLTTWFGALHHIAHYQP
ETDRAPRGLSSEARASLHQWHRRRTLHRK
DHPRAQANLPFKEPWAEETVTGTSDN
Sequence length 566
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
Reactome Pathway
RAB GEFs exchange GTP for GDP on RABs