RHOV (ras homolog family member V)

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Gene miRNA Gene ontology Other IDs Protein Pathways Related genes Diseases linked via similar genes

Gene

• Entrez ID: 171177
• Gene name: Ras homolog family member V
• Gene symbol: RHOV
• Synonyms (NCBI Gene): ARHV, CHP, WRCH2
• Chromosome: 15
• Chromosome location: 15q15.1

miRNA Show/Hide all (182)

miRTarBase ID	miRNA	Experiments	Reference
MIRT019317	hsa-miR-148b-3p	Microarray	17612493
MIRT021431	hsa-miR-9-5p	Microarray	17612493
MIRT002659	hsa-miR-124-3p	Microarray	18668037
MIRT002659	hsa-miR-124-3p	Microarray	15685193
MIRT045896	hsa-miR-125b-5p	CLASH	23622248
MIRT043355	hsa-miR-331-3p	CLASH	23622248
MIRT041402	hsa-miR-193b-3p	CLASH	23622248
MIRT439147	hsa-let-7c-5p	3'LIFE	25074381
MIRT727999	hsa-miR-15a-5p	HITS-CLIP	22473208
MIRT727998	hsa-miR-15b-5p	HITS-CLIP	22473208
MIRT727996	hsa-miR-16-5p	HITS-CLIP	22473208
MIRT727997	hsa-miR-195-5p	HITS-CLIP	22473208
MIRT439147	hsa-let-7c-5p	3'LIFE	25074381
MIRT1306141	hsa-miR-106a	CLIP-seq
MIRT1306142	hsa-miR-106b	CLIP-seq
MIRT1306143	hsa-miR-10a	CLIP-seq
MIRT1306144	hsa-miR-10b	CLIP-seq
MIRT1306145	hsa-miR-1224-5p	CLIP-seq
MIRT1306146	hsa-miR-1258	CLIP-seq
MIRT1306147	hsa-miR-134	CLIP-seq
MIRT1306148	hsa-miR-17	CLIP-seq
MIRT1306149	hsa-miR-20a	CLIP-seq
MIRT1306150	hsa-miR-20b	CLIP-seq
MIRT1306151	hsa-miR-3117-3p	CLIP-seq
MIRT1306152	hsa-miR-3118	CLIP-seq
MIRT1306153	hsa-miR-3136-5p	CLIP-seq
MIRT1306154	hsa-miR-3619-3p	CLIP-seq
MIRT1306155	hsa-miR-3647-3p	CLIP-seq
MIRT1306156	hsa-miR-3689d	CLIP-seq
MIRT1306157	hsa-miR-3915	CLIP-seq
MIRT1306158	hsa-miR-3928	CLIP-seq
MIRT1306159	hsa-miR-3973	CLIP-seq
MIRT1306160	hsa-miR-423-3p	CLIP-seq
MIRT1306161	hsa-miR-4434	CLIP-seq
MIRT1306162	hsa-miR-4439	CLIP-seq
MIRT1306163	hsa-miR-4513	CLIP-seq
MIRT1306164	hsa-miR-4516	CLIP-seq
MIRT1306165	hsa-miR-4531	CLIP-seq
MIRT1306166	hsa-miR-4652-3p	CLIP-seq
MIRT1306167	hsa-miR-4677-3p	CLIP-seq
MIRT1306168	hsa-miR-4679	CLIP-seq
MIRT1306169	hsa-miR-4689	CLIP-seq
MIRT1306170	hsa-miR-4725-5p	CLIP-seq
MIRT1306171	hsa-miR-4755-3p	CLIP-seq
MIRT1306172	hsa-miR-504	CLIP-seq
MIRT1306173	hsa-miR-519d	CLIP-seq
MIRT1306174	hsa-miR-520g	CLIP-seq
MIRT1306175	hsa-miR-520h	CLIP-seq
MIRT1306176	hsa-miR-539	CLIP-seq
MIRT1306177	hsa-miR-93	CLIP-seq
MIRT1306178	hsa-miR-943	CLIP-seq
MIRT1306143	hsa-miR-10a	CLIP-seq
MIRT1306144	hsa-miR-10b	CLIP-seq
MIRT1306147	hsa-miR-134	CLIP-seq
MIRT1306152	hsa-miR-3118	CLIP-seq
MIRT1306153	hsa-miR-3136-5p	CLIP-seq
MIRT1306156	hsa-miR-3689d	CLIP-seq
MIRT1306160	hsa-miR-423-3p	CLIP-seq
MIRT1306162	hsa-miR-4439	CLIP-seq
MIRT1306163	hsa-miR-4513	CLIP-seq
MIRT1306170	hsa-miR-4725-5p	CLIP-seq
MIRT1306172	hsa-miR-504	CLIP-seq
MIRT1306143	hsa-miR-10a	CLIP-seq
MIRT1306144	hsa-miR-10b	CLIP-seq
MIRT1306147	hsa-miR-134	CLIP-seq
MIRT1306152	hsa-miR-3118	CLIP-seq
MIRT1306153	hsa-miR-3136-5p	CLIP-seq
MIRT1306156	hsa-miR-3689d	CLIP-seq
MIRT1306160	hsa-miR-423-3p	CLIP-seq
MIRT1306162	hsa-miR-4439	CLIP-seq
MIRT1306163	hsa-miR-4513	CLIP-seq
MIRT1306170	hsa-miR-4725-5p	CLIP-seq
MIRT1306172	hsa-miR-504	CLIP-seq
MIRT1306141	hsa-miR-106a	CLIP-seq
MIRT1306142	hsa-miR-106b	CLIP-seq
MIRT1306143	hsa-miR-10a	CLIP-seq
MIRT1306144	hsa-miR-10b	CLIP-seq
MIRT1306146	hsa-miR-1258	CLIP-seq
MIRT1306147	hsa-miR-134	CLIP-seq
MIRT2090711	hsa-miR-1470	CLIP-seq
MIRT1306148	hsa-miR-17	CLIP-seq
MIRT2090712	hsa-miR-1915	CLIP-seq
MIRT1306149	hsa-miR-20a	CLIP-seq
MIRT1306150	hsa-miR-20b	CLIP-seq
MIRT2090713	hsa-miR-3074-3p	CLIP-seq
MIRT1306151	hsa-miR-3117-3p	CLIP-seq
MIRT1306152	hsa-miR-3118	CLIP-seq
MIRT1306153	hsa-miR-3136-5p	CLIP-seq
MIRT2090714	hsa-miR-3157-5p	CLIP-seq
MIRT2090715	hsa-miR-3614-3p	CLIP-seq
MIRT2090716	hsa-miR-361-5p	CLIP-seq
MIRT1306154	hsa-miR-3619-3p	CLIP-seq
MIRT1306155	hsa-miR-3647-3p	CLIP-seq
MIRT1306156	hsa-miR-3689d	CLIP-seq
MIRT2090717	hsa-miR-3929	CLIP-seq
MIRT1306159	hsa-miR-3973	CLIP-seq
MIRT1306160	hsa-miR-423-3p	CLIP-seq
MIRT2090718	hsa-miR-4268	CLIP-seq
MIRT2090719	hsa-miR-4284	CLIP-seq
MIRT2090720	hsa-miR-4297	CLIP-seq
MIRT2090721	hsa-miR-4419b	CLIP-seq
MIRT1306161	hsa-miR-4434	CLIP-seq
MIRT1306162	hsa-miR-4439	CLIP-seq
MIRT2090722	hsa-miR-4478	CLIP-seq
MIRT1306163	hsa-miR-4513	CLIP-seq
MIRT1306164	hsa-miR-4516	CLIP-seq
MIRT1306165	hsa-miR-4531	CLIP-seq
MIRT2090723	hsa-miR-4645-5p	CLIP-seq
MIRT1306166	hsa-miR-4652-3p	CLIP-seq
MIRT2090724	hsa-miR-4667-3p	CLIP-seq
MIRT2090725	hsa-miR-4673	CLIP-seq
MIRT1306167	hsa-miR-4677-3p	CLIP-seq
MIRT1306168	hsa-miR-4679	CLIP-seq
MIRT1306170	hsa-miR-4725-5p	CLIP-seq
MIRT2090726	hsa-miR-4726-3p	CLIP-seq
MIRT1306171	hsa-miR-4755-3p	CLIP-seq
MIRT1306172	hsa-miR-504	CLIP-seq
MIRT1306173	hsa-miR-519d	CLIP-seq
MIRT1306174	hsa-miR-520g	CLIP-seq
MIRT1306175	hsa-miR-520h	CLIP-seq
MIRT1306176	hsa-miR-539	CLIP-seq
MIRT2090727	hsa-miR-642a	CLIP-seq
MIRT2090728	hsa-miR-645	CLIP-seq
MIRT1306177	hsa-miR-93	CLIP-seq
MIRT1306141	hsa-miR-106a	CLIP-seq
MIRT1306142	hsa-miR-106b	CLIP-seq
MIRT1306143	hsa-miR-10a	CLIP-seq
MIRT1306144	hsa-miR-10b	CLIP-seq
MIRT1306146	hsa-miR-1258	CLIP-seq
MIRT2315386	hsa-miR-1264	CLIP-seq
MIRT1306147	hsa-miR-134	CLIP-seq
MIRT1306148	hsa-miR-17	CLIP-seq
MIRT2090712	hsa-miR-1915	CLIP-seq
MIRT1306149	hsa-miR-20a	CLIP-seq
MIRT1306150	hsa-miR-20b	CLIP-seq
MIRT1306151	hsa-miR-3117-3p	CLIP-seq
MIRT1306152	hsa-miR-3118	CLIP-seq
MIRT2315387	hsa-miR-3130-5p	CLIP-seq
MIRT1306153	hsa-miR-3136-5p	CLIP-seq
MIRT2090714	hsa-miR-3157-5p	CLIP-seq
MIRT2315388	hsa-miR-3202	CLIP-seq
MIRT1306154	hsa-miR-3619-3p	CLIP-seq
MIRT1306155	hsa-miR-3647-3p	CLIP-seq
MIRT1306156	hsa-miR-3689d	CLIP-seq
MIRT1306159	hsa-miR-3973	CLIP-seq
MIRT1306160	hsa-miR-423-3p	CLIP-seq
MIRT2315389	hsa-miR-4277	CLIP-seq
MIRT1306162	hsa-miR-4439	CLIP-seq
MIRT2315390	hsa-miR-4476	CLIP-seq
MIRT2315391	hsa-miR-4482	CLIP-seq
MIRT1306163	hsa-miR-4513	CLIP-seq
MIRT2315392	hsa-miR-4522	CLIP-seq
MIRT1306166	hsa-miR-4652-3p	CLIP-seq
MIRT1306167	hsa-miR-4677-3p	CLIP-seq
MIRT1306168	hsa-miR-4679	CLIP-seq
MIRT2315393	hsa-miR-4691-3p	CLIP-seq
MIRT2315394	hsa-miR-4722-3p	CLIP-seq
MIRT1306170	hsa-miR-4725-5p	CLIP-seq
MIRT2090726	hsa-miR-4726-3p	CLIP-seq
MIRT1306171	hsa-miR-4755-3p	CLIP-seq
MIRT2315395	hsa-miR-4760-3p	CLIP-seq
MIRT1306172	hsa-miR-504	CLIP-seq
MIRT1306173	hsa-miR-519d	CLIP-seq
MIRT1306174	hsa-miR-520g	CLIP-seq
MIRT1306175	hsa-miR-520h	CLIP-seq
MIRT1306177	hsa-miR-93	CLIP-seq
MIRT1306143	hsa-miR-10a	CLIP-seq
MIRT1306144	hsa-miR-10b	CLIP-seq
MIRT1306147	hsa-miR-134	CLIP-seq
MIRT2090712	hsa-miR-1915	CLIP-seq
MIRT1306152	hsa-miR-3118	CLIP-seq
MIRT1306153	hsa-miR-3136-5p	CLIP-seq
MIRT2393746	hsa-miR-3155	CLIP-seq
MIRT2393747	hsa-miR-3155b	CLIP-seq
MIRT1306156	hsa-miR-3689d	CLIP-seq
MIRT1306160	hsa-miR-423-3p	CLIP-seq
MIRT1306162	hsa-miR-4439	CLIP-seq
MIRT1306163	hsa-miR-4513	CLIP-seq
MIRT1306170	hsa-miR-4725-5p	CLIP-seq
MIRT2090726	hsa-miR-4726-3p	CLIP-seq
MIRT2393748	hsa-miR-484	CLIP-seq
MIRT1306172	hsa-miR-504	CLIP-seq

Gene ontology (GO) Show/Hide all (21)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000166	Function	Nucleotide binding	IEA
GO:0003924	Function	GTPase activity	IBA
GO:0003924	Function	GTPase activity	IEA
GO:0005515	Function	Protein binding	IPI	16752908, 32296183
GO:0005525	Function	GTP binding	IBA
GO:0005525	Function	GTP binding	IEA
GO:0005768	Component	Endosome	IEA
GO:0005886	Component	Plasma membrane	IBA
GO:0005886	Component	Plasma membrane	IEA
GO:0005886	Component	Plasma membrane	TAS
GO:0006897	Process	Endocytosis	IBA
GO:0007010	Process	Cytoskeleton organization	IEA
GO:0007015	Process	Actin filament organization	IBA
GO:0007165	Process	Signal transduction	IBA
GO:0007264	Process	Small GTPase-mediated signal transduction	IEA
GO:0008360	Process	Regulation of cell shape	IEA
GO:0010008	Component	Endosome membrane	IEA
GO:0016020	Component	Membrane	IEA
GO:0019901	Function	Protein kinase binding	IBA
GO:0030010	Process	Establishment of cell polarity	IBA
GO:0046872	Function	Metal ion binding	IEA

Other IDs

• MIM: 620101
• HGNC: 18313
• e!Ensembl: ENSG00000104140

Protein

• UniProt ID: Q96L33
• Protein name: Rho-related GTP-binding protein RhoV (CDC42-like GTPase 2) (GTP-binding protein-like 2) (Rho GTPase-like protein ARHV) (Wnt-1 responsive Cdc42 homolog 2) (WRCH-2)
• Protein function: Plays a role in the control of the actin cytoskeleton via activation of the JNK pathway.
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF00071	Ras	33 → 207	Ras family	Domain

• Tissue specificity: TISSUE SPECIFICITY: Highly expressed in pancreas, placenta, and fetal brain. {ECO:0000269|PubMed:11956592}.
• Sequence:

  MPPRELSEAEPPPLRAPTPPPRRRSAPPELGIKCVLVGDGAVGKSSLIVSYTCNGYPARY
  RPTALDTFSVQVLVDGAPVRIELWDTAGQEDFDRLRSLCYPDTDVFLACFSVVQPSSFQN
  ITEKWLPEIRTHNPQAPVLLVGTQADLRDDVNVLIQLDQGGREGPVPQPQAQGLAEKIRA
  CCYLECSALTQKNLKEVFDSAILSAIEHKARLEKKLNAKGVRTLSRCRWKKFFCFV

• Sequence length: 236

Pathways

Reactome Pathway:

Rho GTPase cycle

Related Genes

No strongly related genes found yet for RHOV.

Diseases Linked via Similar Genes

No additional diseases found yet through genes similar to RHOV.