RHBDD2 (rhomboid domain containing 2)

Download as csv Download as pdf

Log in to bookmark this gene

Bookmark This Gene

Title Project / Tag (optional) Note (optional)

Cancel Save

On this page

Gene miRNA Gene ontology Other IDs Protein Related genes Diseases linked via similar genes

Gene

• Entrez ID: 57414
• Gene name: Rhomboid domain containing 2
• Gene symbol: RHBDD2
• Synonyms (NCBI Gene): NPD007, RHBDL7
• Chromosome: 7
• Chromosome location: 7q11.23
• Summary: The protein encoded by this gene is a member of the rhomboid family of membrane-bound proteases and is overexpressed in some breast cancers. Members of this family are involved in intramembrane proteolysis. In mouse, the orthologous protein associates wit

miRNA Show/Hide all (214)

miRTarBase ID	miRNA	Experiments	Reference
MIRT051463	hsa-let-7e-5p	CLASH	23622248
MIRT1304763	hsa-miR-1226	CLIP-seq
MIRT1304764	hsa-miR-185	CLIP-seq
MIRT1304765	hsa-miR-1909	CLIP-seq
MIRT1304766	hsa-miR-214	CLIP-seq
MIRT1304767	hsa-miR-3117-5p	CLIP-seq
MIRT1304768	hsa-miR-3175	CLIP-seq
MIRT1304769	hsa-miR-3619-5p	CLIP-seq
MIRT1304770	hsa-miR-3649	CLIP-seq
MIRT1304771	hsa-miR-376c	CLIP-seq
MIRT1304772	hsa-miR-3973	CLIP-seq
MIRT1304773	hsa-miR-4306	CLIP-seq
MIRT1304774	hsa-miR-4644	CLIP-seq
MIRT1304775	hsa-miR-4650-5p	CLIP-seq
MIRT1304776	hsa-miR-4672	CLIP-seq
MIRT1304777	hsa-miR-520g	CLIP-seq
MIRT1304778	hsa-miR-520h	CLIP-seq
MIRT1304779	hsa-miR-548k	CLIP-seq
MIRT1304780	hsa-miR-661	CLIP-seq
MIRT1304781	hsa-miR-761	CLIP-seq
MIRT1304782	hsa-miR-3144-5p	CLIP-seq
MIRT1304783	hsa-miR-3165	CLIP-seq
MIRT1304784	hsa-miR-3191	CLIP-seq
MIRT1304785	hsa-miR-4487	CLIP-seq
MIRT1304786	hsa-miR-4633-3p	CLIP-seq
MIRT1304787	hsa-miR-4652-5p	CLIP-seq
MIRT1304788	hsa-miR-4667-5p	CLIP-seq
MIRT1304789	hsa-miR-4700-5p	CLIP-seq
MIRT1304790	hsa-miR-4731-5p	CLIP-seq
MIRT1304791	hsa-miR-4790-3p	CLIP-seq
MIRT1304763	hsa-miR-1226	CLIP-seq
MIRT2090260	hsa-miR-1321	CLIP-seq
MIRT1304767	hsa-miR-3117-5p	CLIP-seq
MIRT2090261	hsa-miR-3166	CLIP-seq
MIRT2090262	hsa-miR-3179	CLIP-seq
MIRT1304770	hsa-miR-3649	CLIP-seq
MIRT1304771	hsa-miR-376c	CLIP-seq
MIRT2090263	hsa-miR-4433	CLIP-seq
MIRT2090264	hsa-miR-4436b-3p	CLIP-seq
MIRT2090265	hsa-miR-4459	CLIP-seq
MIRT2090266	hsa-miR-4643	CLIP-seq
MIRT1304775	hsa-miR-4650-5p	CLIP-seq
MIRT1304788	hsa-miR-4667-5p	CLIP-seq
MIRT1304776	hsa-miR-4672	CLIP-seq
MIRT1304789	hsa-miR-4700-5p	CLIP-seq
MIRT2090267	hsa-miR-4717-3p	CLIP-seq
MIRT2090268	hsa-miR-4739	CLIP-seq
MIRT2090269	hsa-miR-4756-5p	CLIP-seq
MIRT2090270	hsa-miR-4768-3p	CLIP-seq
MIRT2090271	hsa-miR-4802-3p	CLIP-seq
MIRT2090272	hsa-miR-642b	CLIP-seq
MIRT1304780	hsa-miR-661	CLIP-seq
MIRT1304763	hsa-miR-1226	CLIP-seq
MIRT1304782	hsa-miR-3144-5p	CLIP-seq
MIRT1304783	hsa-miR-3165	CLIP-seq
MIRT2090261	hsa-miR-3166	CLIP-seq
MIRT2090262	hsa-miR-3179	CLIP-seq
MIRT1304784	hsa-miR-3191	CLIP-seq
MIRT2090264	hsa-miR-4436b-3p	CLIP-seq
MIRT1304785	hsa-miR-4487	CLIP-seq
MIRT1304786	hsa-miR-4633-3p	CLIP-seq
MIRT2090266	hsa-miR-4643	CLIP-seq
MIRT1304787	hsa-miR-4652-5p	CLIP-seq
MIRT1304788	hsa-miR-4667-5p	CLIP-seq
MIRT1304789	hsa-miR-4700-5p	CLIP-seq
MIRT2090267	hsa-miR-4717-3p	CLIP-seq
MIRT1304790	hsa-miR-4731-5p	CLIP-seq
MIRT1304791	hsa-miR-4790-3p	CLIP-seq
MIRT2090271	hsa-miR-4802-3p	CLIP-seq
MIRT2090272	hsa-miR-642b	CLIP-seq
MIRT1304771	hsa-miR-376c	CLIP-seq
MIRT2611400	hsa-miR-1245b-3p	CLIP-seq
MIRT2611401	hsa-miR-1256	CLIP-seq
MIRT2611402	hsa-miR-1273f	CLIP-seq
MIRT2611403	hsa-miR-1276	CLIP-seq
MIRT2090260	hsa-miR-1321	CLIP-seq
MIRT2611404	hsa-miR-143	CLIP-seq
MIRT2611405	hsa-miR-151-5p	CLIP-seq
MIRT2611406	hsa-miR-151b	CLIP-seq
MIRT2611407	hsa-miR-1911	CLIP-seq
MIRT1304782	hsa-miR-3144-5p	CLIP-seq
MIRT2611408	hsa-miR-3145-5p	CLIP-seq
MIRT2611409	hsa-miR-3160-5p	CLIP-seq
MIRT2611410	hsa-miR-3162-5p	CLIP-seq
MIRT2611411	hsa-miR-3164	CLIP-seq
MIRT1304783	hsa-miR-3165	CLIP-seq
MIRT2611412	hsa-miR-3177-3p	CLIP-seq
MIRT2611413	hsa-miR-3182	CLIP-seq
MIRT2611414	hsa-miR-3189-3p	CLIP-seq
MIRT1304784	hsa-miR-3191	CLIP-seq
MIRT2611415	hsa-miR-3200-5p	CLIP-seq
MIRT2611416	hsa-miR-320e	CLIP-seq
MIRT2611417	hsa-miR-3607-3p	CLIP-seq
MIRT2611418	hsa-miR-3672	CLIP-seq
MIRT2611419	hsa-miR-3686	CLIP-seq
MIRT1304771	hsa-miR-376c	CLIP-seq
MIRT1304772	hsa-miR-3973	CLIP-seq
MIRT2611420	hsa-miR-4270	CLIP-seq
MIRT2611421	hsa-miR-4290	CLIP-seq
MIRT2611422	hsa-miR-4311	CLIP-seq
MIRT2611423	hsa-miR-4312	CLIP-seq
MIRT2611424	hsa-miR-4315	CLIP-seq
MIRT2090263	hsa-miR-4433	CLIP-seq
MIRT2611425	hsa-miR-4441	CLIP-seq
MIRT2611426	hsa-miR-4446-3p	CLIP-seq
MIRT2090265	hsa-miR-4459	CLIP-seq
MIRT2611427	hsa-miR-4480	CLIP-seq
MIRT1304785	hsa-miR-4487	CLIP-seq
MIRT2611428	hsa-miR-4493	CLIP-seq
MIRT2611429	hsa-miR-4502	CLIP-seq
MIRT1304786	hsa-miR-4633-3p	CLIP-seq
MIRT2611430	hsa-miR-4640-5p	CLIP-seq
MIRT1304787	hsa-miR-4652-5p	CLIP-seq
MIRT1304788	hsa-miR-4667-5p	CLIP-seq
MIRT2611431	hsa-miR-4688	CLIP-seq
MIRT2611432	hsa-miR-4691-3p	CLIP-seq
MIRT1304789	hsa-miR-4700-5p	CLIP-seq
MIRT2611433	hsa-miR-4708-5p	CLIP-seq
MIRT2611434	hsa-miR-4712-5p	CLIP-seq
MIRT2611435	hsa-miR-4726-5p	CLIP-seq
MIRT2611436	hsa-miR-4727-5p	CLIP-seq
MIRT1304790	hsa-miR-4731-5p	CLIP-seq
MIRT2090268	hsa-miR-4739	CLIP-seq
MIRT2611437	hsa-miR-4744	CLIP-seq
MIRT2611438	hsa-miR-4751	CLIP-seq
MIRT2611439	hsa-miR-4753-5p	CLIP-seq
MIRT2090269	hsa-miR-4756-5p	CLIP-seq
MIRT2090270	hsa-miR-4768-3p	CLIP-seq
MIRT2611440	hsa-miR-4769-3p	CLIP-seq
MIRT2611441	hsa-miR-4770	CLIP-seq
MIRT1304791	hsa-miR-4790-3p	CLIP-seq
MIRT2611442	hsa-miR-4790-5p	CLIP-seq
MIRT2611443	hsa-miR-494	CLIP-seq
MIRT2611444	hsa-miR-502-5p	CLIP-seq
MIRT2611445	hsa-miR-508-5p	CLIP-seq
MIRT1304777	hsa-miR-520g	CLIP-seq
MIRT1304778	hsa-miR-520h	CLIP-seq
MIRT2611446	hsa-miR-544	CLIP-seq
MIRT1304779	hsa-miR-548k	CLIP-seq
MIRT2611447	hsa-miR-583	CLIP-seq
MIRT2611448	hsa-miR-617	CLIP-seq
MIRT2611449	hsa-miR-720	CLIP-seq
MIRT2611450	hsa-miR-770-5p	CLIP-seq
MIRT2611400	hsa-miR-1245b-3p	CLIP-seq
MIRT2611401	hsa-miR-1256	CLIP-seq
MIRT2611402	hsa-miR-1273f	CLIP-seq
MIRT2611403	hsa-miR-1276	CLIP-seq
MIRT2090260	hsa-miR-1321	CLIP-seq
MIRT2611404	hsa-miR-143	CLIP-seq
MIRT2611405	hsa-miR-151-5p	CLIP-seq
MIRT2611406	hsa-miR-151b	CLIP-seq
MIRT2611407	hsa-miR-1911	CLIP-seq
MIRT1304782	hsa-miR-3144-5p	CLIP-seq
MIRT2611408	hsa-miR-3145-5p	CLIP-seq
MIRT2611409	hsa-miR-3160-5p	CLIP-seq
MIRT2611410	hsa-miR-3162-5p	CLIP-seq
MIRT2611411	hsa-miR-3164	CLIP-seq
MIRT1304783	hsa-miR-3165	CLIP-seq
MIRT2611412	hsa-miR-3177-3p	CLIP-seq
MIRT2611413	hsa-miR-3182	CLIP-seq
MIRT2611414	hsa-miR-3189-3p	CLIP-seq
MIRT1304784	hsa-miR-3191	CLIP-seq
MIRT2611415	hsa-miR-3200-5p	CLIP-seq
MIRT2611416	hsa-miR-320e	CLIP-seq
MIRT2611417	hsa-miR-3607-3p	CLIP-seq
MIRT2611419	hsa-miR-3686	CLIP-seq
MIRT1304771	hsa-miR-376c	CLIP-seq
MIRT1304772	hsa-miR-3973	CLIP-seq
MIRT2611420	hsa-miR-4270	CLIP-seq
MIRT2611421	hsa-miR-4290	CLIP-seq
MIRT2611422	hsa-miR-4311	CLIP-seq
MIRT2611423	hsa-miR-4312	CLIP-seq
MIRT2611424	hsa-miR-4315	CLIP-seq
MIRT2090263	hsa-miR-4433	CLIP-seq
MIRT2611425	hsa-miR-4441	CLIP-seq
MIRT2611426	hsa-miR-4446-3p	CLIP-seq
MIRT2090265	hsa-miR-4459	CLIP-seq
MIRT2611427	hsa-miR-4480	CLIP-seq
MIRT1304785	hsa-miR-4487	CLIP-seq
MIRT2611428	hsa-miR-4493	CLIP-seq
MIRT2611429	hsa-miR-4502	CLIP-seq
MIRT1304786	hsa-miR-4633-3p	CLIP-seq
MIRT2611430	hsa-miR-4640-5p	CLIP-seq
MIRT1304787	hsa-miR-4652-5p	CLIP-seq
MIRT1304788	hsa-miR-4667-5p	CLIP-seq
MIRT2611431	hsa-miR-4688	CLIP-seq
MIRT2611432	hsa-miR-4691-3p	CLIP-seq
MIRT1304789	hsa-miR-4700-5p	CLIP-seq
MIRT2611433	hsa-miR-4708-5p	CLIP-seq
MIRT2611434	hsa-miR-4712-5p	CLIP-seq
MIRT2611435	hsa-miR-4726-5p	CLIP-seq
MIRT2611436	hsa-miR-4727-5p	CLIP-seq
MIRT1304790	hsa-miR-4731-5p	CLIP-seq
MIRT2090268	hsa-miR-4739	CLIP-seq
MIRT2611437	hsa-miR-4744	CLIP-seq
MIRT2611438	hsa-miR-4751	CLIP-seq
MIRT2611439	hsa-miR-4753-5p	CLIP-seq
MIRT2090269	hsa-miR-4756-5p	CLIP-seq
MIRT2090270	hsa-miR-4768-3p	CLIP-seq
MIRT2611440	hsa-miR-4769-3p	CLIP-seq
MIRT2611441	hsa-miR-4770	CLIP-seq
MIRT1304791	hsa-miR-4790-3p	CLIP-seq
MIRT2611442	hsa-miR-4790-5p	CLIP-seq
MIRT2611443	hsa-miR-494	CLIP-seq
MIRT2611444	hsa-miR-502-5p	CLIP-seq
MIRT2611445	hsa-miR-508-5p	CLIP-seq
MIRT1304777	hsa-miR-520g	CLIP-seq
MIRT1304778	hsa-miR-520h	CLIP-seq
MIRT2611446	hsa-miR-544	CLIP-seq
MIRT1304779	hsa-miR-548k	CLIP-seq
MIRT2611447	hsa-miR-583	CLIP-seq
MIRT2611448	hsa-miR-617	CLIP-seq
MIRT2611449	hsa-miR-720	CLIP-seq
MIRT2611450	hsa-miR-770-5p	CLIP-seq

Gene ontology (GO) Show/Hide all (12)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000139	Component	Golgi membrane	IEA
GO:0004252	Function	Serine-type endopeptidase activity	IEA
GO:0005047	Function	Signal recognition particle binding	IBA
GO:0005515	Function	Protein binding	IPI	32296183, 32814053
GO:0005654	Component	Nucleoplasm	IDA
GO:0005789	Component	Endoplasmic reticulum membrane	IBA
GO:0005794	Component	Golgi apparatus	IDA
GO:0005794	Component	Golgi apparatus	IEA
GO:0016020	Component	Membrane	IEA
GO:0030968	Process	Endoplasmic reticulum unfolded protein response	IBA
GO:0036503	Process	ERAD pathway	IBA
GO:0048471	Component	Perinuclear region of cytoplasm	IEA

Other IDs

• MIM: 615203
• HGNC: 23082
• e!Ensembl: ENSG00000005486

Protein

• UniProt ID: Q6NTF9
• Protein name: Rhomboid domain-containing protein 2
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF01694	Rhomboid	54 → 205	Rhomboid family	Family

• Sequence:

  MAASGPGCRSWCLCPEVPSATFFTALLSLLVSGPRLFLLQQPLAPSGLTLKSEALRNWQV
  YRLVTYIFVYENPISLLCGAIIIWRFAGNFERTVGTVRHCFFTVIFAIFSAIIFLSFEAV
  SSLSKLGEVEDARGFTPVAFAMLGVTTVRSRMRRALVFGMVVPSVLVPWLLLGASWLIPQ
  TSFLSNVCGLSIGLAYGLTYCYSIDLSERVALKLDQTFPFSLMRRISVFKYVSGSSAERR
  AAQSRKLNPVPGSYPTQSCHPHLSPSHPVSQTQHASGQKLASWPSCTPGHMPTLPPYQPA
  SGLCYVQNHFGPNPTSSSVYPASAGTSLGIQPPTPVNSPGTVYSGALGTPGAAGSKESSR
  VPMP

• Sequence length: 364

Related Genes

No strongly related genes found yet for RHBDD2.

Diseases Linked via Similar Genes

No additional diseases found yet through genes similar to RHBDD2.