RELL2 (RELT like 2)

Download as csv Download as pdf

Log in to save this analysis

Save This Analysis

Title Project / Tag (optional) Note (optional)

Cancel Save

On this page

Gene miRNA Gene ontology Other IDs Protein Pathways Diseases linked via similar genes

Gene

• Entrez ID: 285613
• Gene name: RELT like 2
• Gene symbol: RELL2
• Synonyms (NCBI Gene): C5orf16
• Chromosome: 5
• Chromosome location: 5q31.3

miRNA Show/Hide all (37)

miRTarBase ID	miRNA	Experiments	Reference
MIRT1300198	hsa-miR-1207-3p	CLIP-seq
MIRT1300199	hsa-miR-1207-5p	CLIP-seq
MIRT1300200	hsa-miR-1909	CLIP-seq
MIRT1300201	hsa-miR-198	CLIP-seq
MIRT1300202	hsa-miR-22	CLIP-seq
MIRT1300203	hsa-miR-2861	CLIP-seq
MIRT1300204	hsa-miR-34a	CLIP-seq
MIRT1300205	hsa-miR-34c-5p	CLIP-seq
MIRT1300206	hsa-miR-449a	CLIP-seq
MIRT1300207	hsa-miR-449b	CLIP-seq
MIRT1300208	hsa-miR-4731-5p	CLIP-seq
MIRT1300209	hsa-miR-4763-3p	CLIP-seq
MIRT1300210	hsa-miR-486-3p	CLIP-seq
MIRT1300211	hsa-miR-512-3p	CLIP-seq
MIRT1300212	hsa-miR-626	CLIP-seq
MIRT1300213	hsa-miR-637	CLIP-seq
MIRT1300199	hsa-miR-1207-5p	CLIP-seq
MIRT1300200	hsa-miR-1909	CLIP-seq
MIRT2314049	hsa-miR-4271	CLIP-seq
MIRT2314050	hsa-miR-4428	CLIP-seq
MIRT2314051	hsa-miR-4514	CLIP-seq
MIRT2314052	hsa-miR-4533	CLIP-seq
MIRT2314053	hsa-miR-4684-3p	CLIP-seq
MIRT2314054	hsa-miR-4692	CLIP-seq
MIRT2314055	hsa-miR-4725-3p	CLIP-seq
MIRT2314056	hsa-miR-4747-5p	CLIP-seq
MIRT1300209	hsa-miR-4763-3p	CLIP-seq
MIRT2314057	hsa-miR-940	CLIP-seq
MIRT2458019	hsa-miR-1252	CLIP-seq
MIRT2458020	hsa-miR-3065-3p	CLIP-seq
MIRT2314050	hsa-miR-4428	CLIP-seq
MIRT2610660	hsa-miR-1972	CLIP-seq
MIRT2610661	hsa-miR-4493	CLIP-seq
MIRT2610662	hsa-miR-4753-5p	CLIP-seq
MIRT2610663	hsa-miR-4755-3p	CLIP-seq
MIRT2610664	hsa-miR-4802-5p	CLIP-seq
MIRT2610665	hsa-miR-487a	CLIP-seq

Gene ontology (GO) Show/Hide all (11)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005515	Function	Protein binding	IPI	22052202, 25416956, 28514442, 32296183, 33961781
GO:0005518	Function	Collagen binding	IEA
GO:0005604	Component	Basement membrane	IEA
GO:0005886	Component	Plasma membrane	IEA
GO:0010811	Process	Positive regulation of cell-substrate adhesion	IBA
GO:0010811	Process	Positive regulation of cell-substrate adhesion	IEA
GO:0016020	Component	Membrane	IEA
GO:0031012	Component	Extracellular matrix	IEA
GO:1900745	Process	Positive regulation of p38MAPK cascade	IBA
GO:1900745	Process	Positive regulation of p38MAPK cascade	IDA	28688764
GO:1900745	Process	Positive regulation of p38MAPK cascade	IEA

Other IDs

• MIM: 611213
• HGNC: 26902
• e!Ensembl: ENSG00000164620

Protein

• UniProt ID: Q8NC24
• Protein name: RELT-like protein 2
• Protein function: Induces activation of MAPK14/p38 cascade, when overexpressed (PubMed:28688764). Induces apoptosis, when overexpressed (PubMed:19969290).
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF12606	RELT	16 → 57	Tumour necrosis factor receptor superfamily member 19	Family

• Tissue specificity: TISSUE SPECIFICITY: Primarily expressed in spleen, thymus, testis, peripheral blood leukocytes, brain and placenta. Not detected in prostate, ovary, small intestine, colon, heart, lung, liver, skeletal muscle, kidney and pancreas. {ECO:0000269|PubMed:1638
• Sequence:

  MSEPQPDLEPPQHGLYMLFLLVLVFFLMGLVGFMICHVLKKKGYRCRTSRGSEPDDAQLQ
  PPEDDDMNEDTVERIVRCIIQNEANAEALKEMLGDSEGEGTVQLSSVDATSSLQDGAPSH
  HHTVHLGSAAPCLHCSRSKRPPLVRQGRSKEGKSRPRTGETTVFSVGRFRVTHIEKRYGL
  HEHRDGSPTDRSWGSGGGQDPGGGQGSGGGQPKAGMPAMERLPPERPQPQVLASPPVQNG
  GLRDSSLTPRALEGNPRASAEPTLRAGGRGPSPGLPTQEANGQPSKPDTSDHQVSLPQGA
  GSM

• Sequence length: 303

Pathways

KEGG Pathway:

Cytokine-cytokine receptor interaction

Related Genes

No strongly related genes found yet for RELL2.

Diseases Linked via Similar Genes

No additional diseases found yet through genes similar to RELL2.