RCBTB2 (RCC1 and BTB domain containing protein 2)

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Gene miRNA Gene ontology Other IDs Protein Related genes Diseases linked via similar genes

Gene

• Entrez ID: 1102
• Gene name: RCC1 and BTB domain containing protein 2
• Gene symbol: RCBTB2
• Synonyms (NCBI Gene): CHC1L, RLG
• Chromosome: 13
• Chromosome location: 13q14.2
• Summary: This gene encodes a protein containing two C-terminal BTB/POZ domains that is related to regulator of chromosome condensation (RCC). The encoded protein may act as a guanine nucleotide exchange factor. This gene is observed to be lost or underexpressed in

miRNA Show/Hide all (160)

miRTarBase ID	miRNA	Experiments	Reference
MIRT026401	hsa-miR-192-5p	Microarray	19074876
MIRT029339	hsa-miR-26b-5p	Microarray	19088304
MIRT1297871	hsa-miR-124	CLIP-seq
MIRT1297872	hsa-miR-129-3p	CLIP-seq
MIRT1297873	hsa-miR-1909	CLIP-seq
MIRT1297874	hsa-miR-2113	CLIP-seq
MIRT1297875	hsa-miR-2861	CLIP-seq
MIRT1297876	hsa-miR-3189-3p	CLIP-seq
MIRT1297877	hsa-miR-3611	CLIP-seq
MIRT1297878	hsa-miR-3688-3p	CLIP-seq
MIRT1297879	hsa-miR-3978	CLIP-seq
MIRT1297880	hsa-miR-4457	CLIP-seq
MIRT1297881	hsa-miR-450b-5p	CLIP-seq
MIRT1297882	hsa-miR-4687-3p	CLIP-seq
MIRT1297883	hsa-miR-4687-5p	CLIP-seq
MIRT1297884	hsa-miR-4694-3p	CLIP-seq
MIRT1297885	hsa-miR-4731-3p	CLIP-seq
MIRT1297886	hsa-miR-4789-5p	CLIP-seq
MIRT1297887	hsa-miR-4801	CLIP-seq
MIRT1297888	hsa-miR-506	CLIP-seq
MIRT1297889	hsa-miR-507	CLIP-seq
MIRT1297890	hsa-miR-557	CLIP-seq
MIRT1297891	hsa-miR-635	CLIP-seq
MIRT1297892	hsa-miR-758	CLIP-seq
MIRT2313491	hsa-miR-3157-5p	CLIP-seq
MIRT2313492	hsa-miR-4427	CLIP-seq
MIRT2313493	hsa-miR-4691-3p	CLIP-seq
MIRT2393592	hsa-miR-326	CLIP-seq
MIRT2393593	hsa-miR-330-5p	CLIP-seq
MIRT2610133	hsa-miR-1202	CLIP-seq
MIRT2610134	hsa-miR-1276	CLIP-seq
MIRT1297872	hsa-miR-129-3p	CLIP-seq
MIRT2610135	hsa-miR-149	CLIP-seq
MIRT2610136	hsa-miR-192	CLIP-seq
MIRT2610137	hsa-miR-2114	CLIP-seq
MIRT2610138	hsa-miR-215	CLIP-seq
MIRT1297875	hsa-miR-2861	CLIP-seq
MIRT2610139	hsa-miR-302f	CLIP-seq
MIRT2610140	hsa-miR-3064-5p	CLIP-seq
MIRT2610141	hsa-miR-3119	CLIP-seq
MIRT2610142	hsa-miR-3125	CLIP-seq
MIRT2610143	hsa-miR-3140-3p	CLIP-seq
MIRT2610144	hsa-miR-3145-3p	CLIP-seq
MIRT2610145	hsa-miR-3145-5p	CLIP-seq
MIRT2313491	hsa-miR-3157-5p	CLIP-seq
MIRT1297876	hsa-miR-3189-3p	CLIP-seq
MIRT2393592	hsa-miR-326	CLIP-seq
MIRT2393593	hsa-miR-330-5p	CLIP-seq
MIRT2610146	hsa-miR-3613-3p	CLIP-seq
MIRT2610147	hsa-miR-3647-3p	CLIP-seq
MIRT2610148	hsa-miR-3691-3p	CLIP-seq
MIRT2610149	hsa-miR-3714	CLIP-seq
MIRT2610150	hsa-miR-3916	CLIP-seq
MIRT2610151	hsa-miR-3918	CLIP-seq
MIRT2610152	hsa-miR-3972	CLIP-seq
MIRT2610153	hsa-miR-4282	CLIP-seq
MIRT2610154	hsa-miR-4311	CLIP-seq
MIRT2610155	hsa-miR-4512	CLIP-seq
MIRT2610156	hsa-miR-4645-3p	CLIP-seq
MIRT2610157	hsa-miR-4662a-3p	CLIP-seq
MIRT2610158	hsa-miR-4685-5p	CLIP-seq
MIRT1297883	hsa-miR-4687-5p	CLIP-seq
MIRT2313493	hsa-miR-4691-3p	CLIP-seq
MIRT2610159	hsa-miR-4729	CLIP-seq
MIRT2610160	hsa-miR-4755-3p	CLIP-seq
MIRT2610161	hsa-miR-4794	CLIP-seq
MIRT2610162	hsa-miR-4797-5p	CLIP-seq
MIRT2610163	hsa-miR-4799-5p	CLIP-seq
MIRT2610164	hsa-miR-485-3p	CLIP-seq
MIRT2610165	hsa-miR-487a	CLIP-seq
MIRT2610166	hsa-miR-502-5p	CLIP-seq
MIRT2610167	hsa-miR-510	CLIP-seq
MIRT2610168	hsa-miR-512-5p	CLIP-seq
MIRT2610169	hsa-miR-522	CLIP-seq
MIRT2610170	hsa-miR-579	CLIP-seq
MIRT2610171	hsa-miR-583	CLIP-seq
MIRT2610172	hsa-miR-616	CLIP-seq
MIRT1297891	hsa-miR-635	CLIP-seq
MIRT2610173	hsa-miR-642a	CLIP-seq
MIRT2610174	hsa-miR-935	CLIP-seq
MIRT2610133	hsa-miR-1202	CLIP-seq
MIRT1297871	hsa-miR-124	CLIP-seq
MIRT2610134	hsa-miR-1276	CLIP-seq
MIRT1297872	hsa-miR-129-3p	CLIP-seq
MIRT2610135	hsa-miR-149	CLIP-seq
MIRT2689599	hsa-miR-181a	CLIP-seq
MIRT2689600	hsa-miR-181b	CLIP-seq
MIRT2689601	hsa-miR-181c	CLIP-seq
MIRT2689602	hsa-miR-181d	CLIP-seq
MIRT1297873	hsa-miR-1909	CLIP-seq
MIRT2610136	hsa-miR-192	CLIP-seq
MIRT2610137	hsa-miR-2114	CLIP-seq
MIRT2610138	hsa-miR-215	CLIP-seq
MIRT1297875	hsa-miR-2861	CLIP-seq
MIRT2610139	hsa-miR-302f	CLIP-seq
MIRT2610140	hsa-miR-3064-5p	CLIP-seq
MIRT2610141	hsa-miR-3119	CLIP-seq
MIRT2610142	hsa-miR-3125	CLIP-seq
MIRT2610143	hsa-miR-3140-3p	CLIP-seq
MIRT2610144	hsa-miR-3145-3p	CLIP-seq
MIRT2610145	hsa-miR-3145-5p	CLIP-seq
MIRT2313491	hsa-miR-3157-5p	CLIP-seq
MIRT2689603	hsa-miR-3160-5p	CLIP-seq
MIRT1297876	hsa-miR-3189-3p	CLIP-seq
MIRT2393592	hsa-miR-326	CLIP-seq
MIRT2393593	hsa-miR-330-5p	CLIP-seq
MIRT2610146	hsa-miR-3613-3p	CLIP-seq
MIRT2610147	hsa-miR-3647-3p	CLIP-seq
MIRT1297878	hsa-miR-3688-3p	CLIP-seq
MIRT2610148	hsa-miR-3691-3p	CLIP-seq
MIRT2610149	hsa-miR-3714	CLIP-seq
MIRT2689604	hsa-miR-380	CLIP-seq
MIRT2689605	hsa-miR-383	CLIP-seq
MIRT2689606	hsa-miR-3910	CLIP-seq
MIRT2610150	hsa-miR-3916	CLIP-seq
MIRT2610151	hsa-miR-3918	CLIP-seq
MIRT2689607	hsa-miR-3924	CLIP-seq
MIRT2610152	hsa-miR-3972	CLIP-seq
MIRT1297879	hsa-miR-3978	CLIP-seq
MIRT2689608	hsa-miR-4262	CLIP-seq
MIRT2610153	hsa-miR-4282	CLIP-seq
MIRT2610154	hsa-miR-4311	CLIP-seq
MIRT2689609	hsa-miR-4330	CLIP-seq
MIRT2689610	hsa-miR-4495	CLIP-seq
MIRT2689611	hsa-miR-4501	CLIP-seq
MIRT1297881	hsa-miR-450b-5p	CLIP-seq
MIRT2610155	hsa-miR-4512	CLIP-seq
MIRT2689612	hsa-miR-4517	CLIP-seq
MIRT2610156	hsa-miR-4645-3p	CLIP-seq
MIRT2610157	hsa-miR-4662a-3p	CLIP-seq
MIRT2689613	hsa-miR-4662a-5p	CLIP-seq
MIRT2610158	hsa-miR-4685-5p	CLIP-seq
MIRT1297883	hsa-miR-4687-5p	CLIP-seq
MIRT2689614	hsa-miR-4690-3p	CLIP-seq
MIRT2313493	hsa-miR-4691-3p	CLIP-seq
MIRT1297884	hsa-miR-4694-3p	CLIP-seq
MIRT2610159	hsa-miR-4729	CLIP-seq
MIRT2610160	hsa-miR-4755-3p	CLIP-seq
MIRT2689615	hsa-miR-4772-5p	CLIP-seq
MIRT2689616	hsa-miR-4786-5p	CLIP-seq
MIRT2610161	hsa-miR-4794	CLIP-seq
MIRT2610162	hsa-miR-4797-5p	CLIP-seq
MIRT2610163	hsa-miR-4799-5p	CLIP-seq
MIRT2610164	hsa-miR-485-3p	CLIP-seq
MIRT2610165	hsa-miR-487a	CLIP-seq
MIRT2610166	hsa-miR-502-5p	CLIP-seq
MIRT1297888	hsa-miR-506	CLIP-seq
MIRT1297889	hsa-miR-507	CLIP-seq
MIRT2610167	hsa-miR-510	CLIP-seq
MIRT2610168	hsa-miR-512-5p	CLIP-seq
MIRT2610169	hsa-miR-522	CLIP-seq
MIRT2689617	hsa-miR-543	CLIP-seq
MIRT1297890	hsa-miR-557	CLIP-seq
MIRT2610170	hsa-miR-579	CLIP-seq
MIRT2610171	hsa-miR-583	CLIP-seq
MIRT2610172	hsa-miR-616	CLIP-seq
MIRT1297891	hsa-miR-635	CLIP-seq
MIRT2610173	hsa-miR-642a	CLIP-seq
MIRT2689618	hsa-miR-769-5p	CLIP-seq
MIRT2610174	hsa-miR-935	CLIP-seq

Gene ontology (GO) Show/Hide all (10)

GO ID	Ontology	Definition	Evidence	Reference
GO:0001669	Component	Acrosomal vesicle	IEA
GO:0001889	Process	Liver development	IEA
GO:0005085	Function	Guanyl-nucleotide exchange factor activity	TAS	9806834
GO:0005515	Function	Protein binding	IPI	25036637, 25416956, 32296183, 33961781
GO:0005737	Component	Cytoplasm	IBA
GO:0008283	Process	Cell population proliferation	IEA
GO:0031410	Component	Cytoplasmic vesicle	IEA
GO:0048535	Process	Lymph node development	IEA
GO:0048536	Process	Spleen development	IEA
GO:0048565	Process	Digestive tract development	IEA

Other IDs

• MIM: 603524
• HGNC: 1914
• e!Ensembl: ENSG00000136161

Protein

• UniProt ID: O95199
• Protein name: RCC1 and BTB domain-containing protein 2 (Chromosome condensation 1-like) (CHC1-L) (RCC1-like G exchanging factor) (Regulator of chromosome condensation and BTB domain-containing protein 2)
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF00415	RCC1	223 → 272	Regulator of chromosome condensation (RCC1) repeat	Repeat
  PF00415	RCC1	117 → 167	Regulator of chromosome condensation (RCC1) repeat	Repeat
  PF00415	RCC1	170 → 220	Regulator of chromosome condensation (RCC1) repeat	Repeat
  PF00415	RCC1	275 → 324	Regulator of chromosome condensation (RCC1) repeat	Repeat
  PF00651	BTB	384 → 487	BTB/POZ domain	Domain

• Sequence:

  MEEELPLFSGDSGKPVQATLSSLKMLDVGKWPIFSLCSEEELQLIRQACVFGSAGNEVLY
  TTVNDEIFVLGTNCCGCLGLGDVQSTIEPRRLDSLNGKKIACLSYGSGPHIVLATTEGEV
  FTWGHNAYSQLGNGTTNHGLVPCHISTNLSNKQVIEVACGSYHSLVLTSDGEVFAWGYNN
  SGQVGSGSTVNQPIPRRVTGCLQNKVVVTIACGQMCCMAVVDTGEVYVWGYNGNGQLGLG
  NSGNQPTPCRVAALQGIRVQRVACGYAHTLVLTDEGQVYAWGANSYGQLGTGNKSNQSYP
  TPVTVEKDRIIEIAACHSTHTSAAKTQGGHVYMWGQCRGQSVILPHLTHFSCTDDVFACF
  ATPAVTWRLLSVEPDDHLTVAESLKREFDNPDTADLKFLVDGKYIYAHKVLLKIRCEHFR
  SSLEDNEDDIVEMSEFSYPVYRAFLEYLYTDSISLSPEEAVGLLDLATFYRENRLKKLCQ
  QTIKQGICEENAIALLSAAVKYDAQDLEEFCFRFCINHLTVVTQTSGFAEMDHDLLKNFI
  SKASRVGAFKN

• Sequence length: 551

Related Genes

No strongly related genes found yet for RCBTB2.

Diseases Linked via Similar Genes

No additional diseases found yet through genes similar to RCBTB2.