RBM26 (RNA binding motif protein 26)

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Gene miRNA Gene ontology Other IDs Protein Associated diseases Related genes Diseases linked via similar genes

Gene

• Entrez ID: 64062
• Gene name: RNA binding motif protein 26
• Gene symbol: RBM26
• Synonyms (NCBI Gene): ARRS2, C13orf10, PPP1R132, PRO1777, SE70-2, ZC3H17
• Chromosome: 13
• Chromosome location: 13q31.1

miRNA Show/Hide all (71)

miRTarBase ID	miRNA	Experiments	Reference
MIRT025266	hsa-miR-34a-5p	Proteomics	21566225
MIRT025266	hsa-miR-34a-5p	Proteomics	21566225
MIRT042946	hsa-miR-324-3p	CLASH	23622248
MIRT439804	ebv-miR-BART10-3p	HITS-CLIP	22473208
MIRT439803	hsa-miR-374a-5p	HITS-CLIP	22473208
MIRT439804	ebv-miR-BART10-3p	HITS-CLIP	22473208
MIRT439803	hsa-miR-374a-5p	HITS-CLIP	22473208
MIRT1295577	hsa-miR-1276	CLIP-seq
MIRT1295578	hsa-miR-23a	CLIP-seq
MIRT1295579	hsa-miR-23b	CLIP-seq
MIRT1295580	hsa-miR-23c	CLIP-seq
MIRT1295581	hsa-miR-3662	CLIP-seq
MIRT1295582	hsa-miR-380	CLIP-seq
MIRT1295583	hsa-miR-4311	CLIP-seq
MIRT1295584	hsa-miR-4495	CLIP-seq
MIRT1295585	hsa-miR-4786-5p	CLIP-seq
MIRT1295586	hsa-miR-520d-5p	CLIP-seq
MIRT1295587	hsa-miR-524-5p	CLIP-seq
MIRT1295588	hsa-miR-583	CLIP-seq
MIRT2087801	hsa-miR-153	CLIP-seq
MIRT2087802	hsa-miR-2054	CLIP-seq
MIRT2087803	hsa-miR-2964a-5p	CLIP-seq
MIRT2087804	hsa-miR-3065-5p	CLIP-seq
MIRT2087805	hsa-miR-374c	CLIP-seq
MIRT2087806	hsa-miR-376c	CLIP-seq
MIRT1295582	hsa-miR-380	CLIP-seq
MIRT2087807	hsa-miR-3908	CLIP-seq
MIRT2087808	hsa-miR-3942-5p	CLIP-seq
MIRT2087809	hsa-miR-4307	CLIP-seq
MIRT2087810	hsa-miR-4422	CLIP-seq
MIRT2087811	hsa-miR-448	CLIP-seq
MIRT1295584	hsa-miR-4495	CLIP-seq
MIRT2087812	hsa-miR-455-3p	CLIP-seq
MIRT2087813	hsa-miR-4672	CLIP-seq
MIRT2087814	hsa-miR-4703-5p	CLIP-seq
MIRT2087815	hsa-miR-4724-5p	CLIP-seq
MIRT2087816	hsa-miR-4766-3p	CLIP-seq
MIRT2087817	hsa-miR-548ac	CLIP-seq
MIRT2087818	hsa-miR-548ae	CLIP-seq
MIRT2087819	hsa-miR-548aj	CLIP-seq
MIRT2087820	hsa-miR-548am	CLIP-seq
MIRT2087821	hsa-miR-548d-3p	CLIP-seq
MIRT2087822	hsa-miR-548x	CLIP-seq
MIRT2087823	hsa-miR-548z	CLIP-seq
MIRT2087824	hsa-miR-655	CLIP-seq
MIRT2087825	hsa-miR-664	CLIP-seq
MIRT2087804	hsa-miR-3065-5p	CLIP-seq
MIRT2312709	hsa-miR-3168	CLIP-seq
MIRT2087805	hsa-miR-374c	CLIP-seq
MIRT2087806	hsa-miR-376c	CLIP-seq
MIRT2312710	hsa-miR-383	CLIP-seq
MIRT2312711	hsa-miR-3909	CLIP-seq
MIRT2312712	hsa-miR-4451	CLIP-seq
MIRT2087812	hsa-miR-455-3p	CLIP-seq
MIRT2087813	hsa-miR-4672	CLIP-seq
MIRT2087824	hsa-miR-655	CLIP-seq
MIRT2087825	hsa-miR-664	CLIP-seq
MIRT2457877	hsa-miR-1270	CLIP-seq
MIRT2457878	hsa-miR-369-3p	CLIP-seq
MIRT2457879	hsa-miR-374a	CLIP-seq
MIRT2457880	hsa-miR-374b	CLIP-seq
MIRT2087805	hsa-miR-374c	CLIP-seq
MIRT2457881	hsa-miR-432	CLIP-seq
MIRT2457882	hsa-miR-4531	CLIP-seq
MIRT2457883	hsa-miR-620	CLIP-seq
MIRT2087824	hsa-miR-655	CLIP-seq
MIRT2457884	hsa-miR-656	CLIP-seq
MIRT2457885	hsa-miR-890	CLIP-seq
MIRT1295578	hsa-miR-23a	CLIP-seq
MIRT1295579	hsa-miR-23b	CLIP-seq
MIRT1295580	hsa-miR-23c	CLIP-seq

Gene ontology (GO) Show/Hide all (8)

GO ID	Ontology	Definition	Evidence	Reference
GO:0003676	Function	Nucleic acid binding	IEA
GO:0003723	Function	RNA binding	HDA	22658674, 22681889
GO:0003723	Function	RNA binding	IBA
GO:0003723	Function	RNA binding	IEA
GO:0005515	Function	Protein binding	IPI	17577209, 25416956
GO:0005634	Component	Nucleus	IBA
GO:0008270	Function	Zinc ion binding	IEA
GO:0046872	Function	Metal ion binding	IEA

Other IDs

• MIM: 620081
• HGNC: 20327
• e!Ensembl: ENSG00000139746

Protein

• UniProt ID: Q5T8P6
• Protein name: RNA-binding protein 26 (CTCL tumor antigen se70-2) (RNA-binding motif protein 26)
• Protein function: May be involved in the turnover of nuclear polyadenylated (pA+) RNA.
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF01480	PWI	11 → 81	PWI domain	Family

• Sequence:

  MVSKMIIENFEALKSWLSKTLEPICDADPSALAKYVLALVKKDKSEKELKALCIDQLDVF
  LQKETQIFVEKLFDAVNTKSYLPPPEQPSSGSLKVEFFPHQEKDIKKEEITKEEEREKKF
  SRRLNHSPPQSSSRYRENRSRDERKKDDRSRKRDYDRNPPRRDSYRDRYNRRRGRSRSYS
  RSRSRSWSKERLRERDRDRSRTRSRSRTRSRERDLVKPKYDLDRTDPLENNYTPVSSVPS
  ISSGHYPVPTLSSTITVIAPTHHGNNTTESWSEFHEDQVDHNSYVRPPMPKKRCRDYDEK
  GFCMRGDMCPFDHGSDPVVVEDVNLPGMLPFPAQPPVVEGPPPPGLPPPPPILTPPPVNL
  RPPVPPPGPLPPSLPPVTGPPPPLPPLQPSGMDAPPNSATSSVPTVVTTGIHHQPPPAPP
  SLFTADTYDTDGYNPEAPSITNTSRPMYRHRVHAQRPNLIGLTSGDMDLPPREKPPNKSS
  MRIVVDSESRKRTIGSGEPGVPTKKTWFDKPNFNRTNSPGFQKKVQFGNENTKLELRKVP
  PELNNISKLNEHFSRFGTLVNLQVAYNGDPEGALIQFATYEEAKKAISSTEAVLNNRFIK
  VYWHREGSTQQLQTTSPKVMQPLVQQPILPVVKQSVKERLGPVPSSTIEPAEAQSASSDL
  PQNVTKLSVKDRLGFVSKPSVSATEKVLSTSTGLTKTVYNPAALKAAQKTLLVSTSAVDN
  NEAQKKKQEALKLQQDVRKRKQEILEKHIETQKMLISKLEKNKTMKSEDKAEIMKTLEVL
  TKNITKLKDEVKAASPGRCLPKSIKTKTQMQKELLDTELDLYKKMQAGEEVTELRRKYTE
  LQLEAAKRGILSSGRGRGIHSRGRGAVHGRGRGRGRGRGVPGHAVVDHRPRALEISAFTE
  SDREDLLPHFAQYGEIEDCQIDDSSLHAVITFKTRAEAEAAAVHGARFKGQDLKLAWNKP
  VTNISAVETEEVEPDEEEFQEESLVDDSLLQDDDEEEEDNESRSWRR

• Sequence length: 1007

Associated diseases

Evidence Score:

• ★☆☆☆☆  Gene-disease association found in Text Mining only
• ★★☆☆☆  Found in Text Mining and Unknown/Other Associations
• ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources
• ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
• ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Unknown / Other Associations Show/Hide Unknown Diseases (16)
Phenotype Name	Clinical Significance	Source	Reference	Evidence Score
Acute myeloid leukemia	Benign	ClinVar	—	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
ANOREXIA NERVOSA	—	GWAS catalog	36738649	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
ATTENTION DEFICIT HYPERACTIVITY DISORDER	—	GWAS catalog	36738649	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Cervical cancer	Benign	ClinVar	—	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Cholangiocarcinoma	Benign	ClinVar	—	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Clear cell carcinoma of kidney	Benign	ClinVar	—	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Gastric cancer	Benign	ClinVar	—	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Lung cancer	Benign	ClinVar	—	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Malignant tumor of esophagus	Benign	ClinVar	—	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Ovarian serous cystadenocarcinoma	Benign	ClinVar	—	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Sarcoma	Benign	ClinVar	—	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
SCHIZOPHRENIA	—	GWAS catalog	26198764, 35396580, 39753749	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Thymoma	Benign	ClinVar	—	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
TYPE 2 DIABETES MELLITUS	—	GWAS catalog	36738649	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Uterine carcinosarcoma	Benign	ClinVar	—	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Uterine corpus endometrial carcinoma	Benign	ClinVar	—	★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Associations from Text Mining
Disease Name	Disease (Merged)	Source	PMID	Relationship Type	Evidence Score
Anthracosis	Anthracosis	CTD_human_DG	29394417		★☆☆☆☆ Found in Text Mining only
Lymphoma	Lymphoma	Pubtator	15161670	Associate	★☆☆☆☆ Found in Text Mining only

Related Genes

No strongly related genes found yet for RBM26.

Diseases Linked via Similar Genes

No additional diseases found yet through genes similar to RBM26.