RBBP9 (RB binding protein 9, serine hydrolase)
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Gene
Gene information from NCBI Gene database.
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| Entrez ID | 10741 |
| Gene name | RB binding protein 9, serine hydrolase |
| Gene symbol | RBBP9 |
| Synonyms (NCBI Gene) |
BOGRBBP10
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| Chromosome | 20 |
| Chromosome location | 20p11.23 |
| Summary | The protein encoded by this gene is a retinoblastoma binding protein that may play a role in the regulation of cell proliferation and differentiation. Two alternatively spliced transcript variants of this gene with identical predicted protein products hav |
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miRNA
miRNA information provided by mirtarbase database.
450
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Gene ontology (GO)
Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
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Other IDs
Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
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Protein
Protein information from UniProt database.
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UniProt ID
Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
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O75884 | ||||||||||
| Protein name | Serine hydrolase RBBP9 (EC 3.1.-.-) (B5T-overexpressed gene protein) (Protein BOG) (Retinoblastoma-binding protein 10) (RBBP-10) (Retinoblastoma-binding protein 9) (RBBP-9) | ||||||||||
| Protein function | Serine hydrolase (Probable) (PubMed:32196348). Catalyzes the hydrolytic activation of amino acid ester of the antiviral prodrug valacyclovir to its corresponding active drug, acyclovir (PubMed:32196348). May negatively regulate basal or autocrin | ||||||||||
| PDB | 2QS9 , 7OEX , 9FCR | ||||||||||
| Family and domains |
Pfam
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| Tissue specificity | TISSUE SPECIFICITY: Expressed at higher levels in tumor tissues such as carcinoma. {ECO:0000269|PubMed:20080647, ECO:0000269|PubMed:9697699}. | ||||||||||
| Sequence |
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| Sequence length | 186 | ||||||||||
| Interactions | View interactions | ||||||||||
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Related Genes
Genes most often co-reported with RBBP9 across shared curated disease and pathway associations.
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Diseases Linked via Similar Genes
Diseases curated for genes most similar to RBBP9 (see Related Genes above), that are NOT already directly curated for RBBP9 itself -- a lead worth checking, not a confirmed association.
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