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Gene Gene information from NCBI Gene database.
Entrez ID 10741
Gene name RB binding protein 9, serine hydrolase
Gene symbol RBBP9
Synonyms (NCBI Gene)
BOGRBBP10
Chromosome 20
Chromosome location 20p11.23
Summary The protein encoded by this gene is a retinoblastoma binding protein that may play a role in the regulation of cell proliferation and differentiation. Two alternatively spliced transcript variants of this gene with identical predicted protein products hav
miRNA miRNA information provided by mirtarbase database.
450 Show/Hide all (450)
miRTarBase ID miRNA Experiments Reference
MIRT023005 hsa-miR-124-3p Microarray 18668037
MIRT295390 hsa-miR-4733-5p HITS-CLIP 23824327
MIRT673419 hsa-miR-214-5p HITS-CLIP 23824327
MIRT673418 hsa-miR-6811-3p HITS-CLIP 23824327
MIRT673417 hsa-miR-6847-3p HITS-CLIP 23824327
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
9 Show/Hide all (9)
GO ID Ontology Definition Evidence Reference
GO:0005515 Function Protein binding IPI 21044950, 32296183
GO:0005654 Component Nucleoplasm IDA
GO:0006805 Process Xenobiotic metabolic process IDA 32196348
GO:0009624 Process Response to nematode IEA
GO:0010628 Process Positive regulation of gene expression IEA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
602908 9892 ENSG00000089050
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
O75884
Protein name Serine hydrolase RBBP9 (EC 3.1.-.-) (B5T-overexpressed gene protein) (Protein BOG) (Retinoblastoma-binding protein 10) (RBBP-10) (Retinoblastoma-binding protein 9) (RBBP-9)
Protein function Serine hydrolase (Probable) (PubMed:32196348). Catalyzes the hydrolytic activation of amino acid ester of the antiviral prodrug valacyclovir to its corresponding active drug, acyclovir (PubMed:32196348). May negatively regulate basal or autocrin
PDB 2QS9 , 7OEX , 9FCR
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF06821 Ser_hydrolase 7 → 184 Serine hydrolase Domain
Tissue specificity TISSUE SPECIFICITY: Expressed at higher levels in tumor tissues such as carcinoma. {ECO:0000269|PubMed:20080647, ECO:0000269|PubMed:9697699}.
Sequence
Sequence length 186
Interactions View interactions