Gene Gene information from NCBI Gene database. Download as csv Download as pdf
Entrez ID	100271927
Gene name	RAS p21 protein activator 4B
Gene symbol	RASA4B
Synonyms (NCBI Gene)	-
Chromosome	7
Chromosome location	7q22.1

miRTarBase ID	miRNA	Experiments	Reference
MIRT018773	hsa-miR-335-5p	Microarray	18185580

13 Show/Hide all (13)

GO ID	Ontology	Definition	Evidence
GO:0005096	Function	GTPase activator activity	IBA
GO:0005096	Function	GTPase activator activity	IEA
GO:0005543	Function	Phospholipid binding	IEA
GO:0005737	Component	Cytoplasm	IEA
GO:0005829	Component	Cytosol	IEA
GO:0005886	Component	Plasma membrane	IEA
GO:0008270	Function	Zinc ion binding	IEA
GO:0016020	Component	Membrane	IEA
GO:0035556	Process	Intracellular signal transduction	IEA
GO:0046580	Process	Negative regulation of Ras protein signal transduction	IEA
GO:0046872	Function	Metal ion binding	IEA
GO:0071277	Process	Cellular response to calcium ion	IEA
GO:1902531	Process	Regulation of intracellular signal transduction	IBA

MIM	HGNC	e!Ensembl
HGNC	N/A	HGNC

C9J798

Protein name

Ras GTPase-activating protein 4B

Protein function

Ca(2+)-dependent Ras GTPase-activating protein, that may play a role in the Ras-MAPK pathway.

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00168	C2	133 → 234	C2 domain	Domain
PF00168	C2	5 → 107	C2 domain	Domain
PF00169	PH	567 → 672	PH domain	Domain
PF00616	RasGAP	323 → 512	GTPase-activator protein for Ras-like GTPase	Family
PF00779	BTK	681 → 710	BTK motif	Motif

Sequence

MAKRSSLYIRIVEGKNLPAKDITGSSDPYCIVKVDNEPIIRTATVWKTLCPFWGEEYQVH
LPPTFHAVAFYVMDEDALSRDDVIGKVCLTRDTIASHPKGFSGWAHLTEVDPDEEVQGEI
HLRLEVWPGARACRLRCSVLEARDLAPKDRNGTSDPFVRVRYKGRTRETSIVKKSCYPRW
NETFEFELQEGAMEALCVEAWDWDLVSRNDFLGKVVIDVQRLRVVQQEEGWFRLQPDQSK
SRRHDEGNLGSLQLEVRLRDETVLPSSYYQPLVHLLCHEVKLGMQGPGQLIPLIEETTST
ECRQDVATNLLKLFLGQGLAKDFLDLLFQLELSRTSETNTLFRSNSLASKSVESFLKVAG
MQYLHGVLGPIINKVFEEKKYVELDPSKVEVKDVGCSGLHRPQTEAEVLEQSAQTLRAHL
GALLSALSRSVRACPAVVRATFRQLFRRVRERFPGAQHENVPFIAVTSFLCLRFFSPAIM
SPKLFHLRERHADARTSRTLLLLAKAVQNVGNMDTPASRAKEAWMEPLQPTVHQGVAQLK
DFITKLVDIEEKDELDLQRTLSLQAPPVKEGPLFIHRTKGKGPLMSSSFKKLYFSLTTEA
LSFAKTPSSKKSALIKLANIRAAEKVEEKSFGGSHVMQVIYTDDAGRPQTAYLQCKCVNE
LNQWLSALRKVSINNTGLLGSYHPGVFRGDKWSCCHQKEKTGQGCDKTRSRVTLQEWNDP
LDHDLEAQLIYRHLLGVEAMLWERHRELSGGAEAGTVPTSPGKVPEDSLARLLRVLQDLR
EAHSSSPAGSPPSEPNCLLELQT

Sequence length

803

Interactions

View interactions

KEGG Pathway
Ras signaling pathway

Related Genes Genes most often co-reported with RASA4B across shared curated disease and pathway associations. 0 Download as csv Download as pdf
No strongly related genes found yet for RASA4B.

Diseases Linked via Similar Genes Diseases curated for genes most similar to RASA4B (see Related Genes above), that are NOT already directly curated for RASA4B itself -- a lead worth checking, not a confirmed association. 0 Download as csv Download as pdf
No additional diseases found yet through genes similar to RASA4B.

RASA4B (RAS p21 protein activator 4B)

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