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Gene Gene information from NCBI Gene database.
Entrez ID 57826
Gene name RAP2C, member of RAS oncogene family
Gene symbol RAP2C
Synonyms (NCBI Gene)
-
Chromosome X
Chromosome location Xq26.2
Summary The protein encoded by this gene is a member of the Ras-related protein subfamily of the Ras GTPase superfamily. Members of this family are small GTPases that act as molecular switches to regulate cellular proliferation, differentiation, and apoptosis. Th
miRNA miRNA information provided by mirtarbase database.
616 Show/Hide all (616)
miRTarBase ID miRNA Experiments Reference
MIRT016688 hsa-miR-423-3p Sequencing 20371350
MIRT019855 hsa-miR-375 Microarray 20215506
MIRT020214 hsa-miR-130b-3p Sequencing 20371350
MIRT028204 hsa-miR-33a-5p Sequencing 20371350
MIRT029388 hsa-miR-26b-5p Sequencing 20371350
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
42 Show/Hide all (42)
GO ID Ontology Definition Evidence Reference
GO:0000166 Function Nucleotide binding IEA
GO:0003713 Function Transcription coactivator activity IDA 17447155
GO:0003924 Function GTPase activity IBA
GO:0003924 Function GTPase activity IEA
GO:0003925 Function G protein activity IEA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
301016 21165 ENSG00000123728
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q9Y3L5
Protein name Ras-related protein Rap-2c (EC 3.6.5.2)
Protein function Small GTP-binding protein which cycles between a GDP-bound inactive and a GTP-bound active form. May play a role in cytoskeletal rearrangements and regulate cell spreading through activation of the effector TNIK. May play a role in SRE-mediated
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00071 Ras 5 → 166 Ras family Domain
Tissue specificity TISSUE SPECIFICITY: Expressed in liver, skeletal muscle, prostate, uterus, rectum, stomach, and bladder and to a lower extent in brain, kidney, pancreas, and bone marrow. Expressed in mononuclear leukocytes and megakaryocytes. {ECO:0000269|PubMed:16213650
Sequence
Sequence length 183
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
KEGG Pathway Reactome Pathway
Tight junction Neutrophil degranulation