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Gene Gene information from NCBI Gene database.
Entrez ID 5912
Gene name RAP2B, member of RAS oncogene family
Gene symbol RAP2B
Synonyms (NCBI Gene)
-
Chromosome 3
Chromosome location 3q25.2
Summary This intronless gene belongs to a family of RAS-related genes. The proteins encoded by these genes share approximately 50% amino acid identity with the classical RAS proteins and have numerous structural features in common. The most striking difference be
miRNA miRNA information provided by mirtarbase database.
1170 Show/Hide all (1170)
miRTarBase ID miRNA Experiments Reference
MIRT044000 hsa-miR-378a-5p CLASH 23622248
MIRT043238 hsa-miR-324-5p CLASH 23622248
MIRT627744 hsa-miR-548ac HITS-CLIP 19536157
MIRT627743 hsa-miR-548bb-3p HITS-CLIP 19536157
MIRT627742 hsa-miR-548d-3p HITS-CLIP 19536157
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
45 Show/Hide all (45)
GO ID Ontology Definition Evidence Reference
GO:0000166 Function Nucleotide binding IEA
GO:0003924 Function GTPase activity IBA
GO:0003924 Function GTPase activity IEA
GO:0003925 Function G protein activity IEA
GO:0005515 Function Protein binding IPI 16189514, 25416956, 32296183
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
179541 9862 ENSG00000181467
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
P61225
Protein name Ras-related protein Rap-2b (EC 3.6.5.2)
Protein function Small GTP-binding protein which cycles between a GDP-bound inactive and a GTP-bound active form. Involved in EGFR and CHRM3 signaling pathways through stimulation of PLCE1. May play a role in cytoskeletal rearrangements and regulate cell spreadi
PDB 1N4P , 1N4Q , 1N4R
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00071 Ras 5 → 166 Ras family Domain
Tissue specificity TISSUE SPECIFICITY: Expressed in red blood cells (at protein level). {ECO:0000269|PubMed:16540189}.
Sequence
Sequence length 183
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
Reactome Pathway
Neutrophil degranulation