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Gene Gene information from NCBI Gene database.
Entrez ID 5877
Gene name RAB interacting factor
Gene symbol RABIF
Synonyms (NCBI Gene)
MSS4RASGFR3RASGRF3
Chromosome 1
Chromosome location 1q32.1
Summary This gene encodes a member of the SCE4/YPT1/RAB family of small GTP-binding proteins that are involved in the regulation of intracellular vesicular transport. This protein stimulates GTP-GDP exchange in SEC4, and to a lesser extent in YPT1 and RAB3A, and
miRNA miRNA information provided by mirtarbase database.
260 Show/Hide all (260)
miRTarBase ID miRNA Experiments Reference
MIRT654506 hsa-miR-5571-5p HITS-CLIP 23824327
MIRT654505 hsa-miR-1224-3p HITS-CLIP 23824327
MIRT654504 hsa-miR-150-5p HITS-CLIP 23824327
MIRT654503 hsa-miR-2116-3p HITS-CLIP 23824327
MIRT654502 hsa-miR-1260a HITS-CLIP 23824327
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
14 Show/Hide all (14)
GO ID Ontology Definition Evidence Reference
GO:0005085 Function Guanyl-nucleotide exchange factor activity IBA
GO:0005085 Function Guanyl-nucleotide exchange factor activity IEA
GO:0005085 Function Guanyl-nucleotide exchange factor activity NAS 7619808
GO:0005085 Function Guanyl-nucleotide exchange factor activity TAS 9441742
GO:0005515 Function Protein binding IPI 16541104, 21044950, 25416956, 26824392, 28514442, 29125462, 32296183, 33961781, 35271311
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
603417 9797 ENSG00000183155
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
P47224
Protein name Guanine nucleotide exchange factor MSS4 (Rab-interacting factor)
Protein function Guanine-nucleotide-releasing protein that acts on members of the SEC4/YPT1/RAB subfamily. Stimulates GDP release from both YPT1, RAB3A and RAB10, but is less active on these proteins than on the SEC4 protein (PubMed:31540829). Might play a gener
PDB 1FWQ , 2FU5
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF04421 Mss4 27 → 122 Mss4 protein Domain
Tissue specificity TISSUE SPECIFICITY: Ubiquitous.
Sequence
Sequence length 123
Interactions View interactions