RABIF (RAB interacting factor)
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Gene
Gene information from NCBI Gene database.
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| Entrez ID | 5877 |
| Gene name | RAB interacting factor |
| Gene symbol | RABIF |
| Synonyms (NCBI Gene) |
MSS4RASGFR3RASGRF3
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| Chromosome | 1 |
| Chromosome location | 1q32.1 |
| Summary | This gene encodes a member of the SCE4/YPT1/RAB family of small GTP-binding proteins that are involved in the regulation of intracellular vesicular transport. This protein stimulates GTP-GDP exchange in SEC4, and to a lesser extent in YPT1 and RAB3A, and |
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miRNA
miRNA information provided by mirtarbase database.
260
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Gene ontology (GO)
Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
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Other IDs
Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
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Protein
Protein information from UniProt database.
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UniProt ID
Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
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P47224 | ||||||||||
| Protein name | Guanine nucleotide exchange factor MSS4 (Rab-interacting factor) | ||||||||||
| Protein function | Guanine-nucleotide-releasing protein that acts on members of the SEC4/YPT1/RAB subfamily. Stimulates GDP release from both YPT1, RAB3A and RAB10, but is less active on these proteins than on the SEC4 protein (PubMed:31540829). Might play a gener | ||||||||||
| PDB | 1FWQ , 2FU5 | ||||||||||
| Family and domains |
Pfam
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| Tissue specificity | TISSUE SPECIFICITY: Ubiquitous. | ||||||||||
| Sequence |
MEPAEQPSELVSAEGRNRKAVLCQRCGSRVLQPGTALFSRRQLFLPSMRKKPALSDGSNP |
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| Sequence length | 123 | ||||||||||
| Interactions | View interactions | ||||||||||
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Related Genes
Genes most often co-reported with RABIF across shared curated disease and pathway associations.
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Diseases Linked via Similar Genes
Diseases curated for genes most similar to RABIF (see Related Genes above), that are NOT already directly curated for RABIF itself -- a lead worth checking, not a confirmed association.
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