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Gene Gene information from NCBI Gene database.
Entrez ID 84932
Gene name RAB2B, member RAS oncogene family
Gene symbol RAB2B
Synonyms (NCBI Gene)
-
Chromosome 14
Chromosome location 14q11.2
Summary Members of the Rab protein family are nontransforming monomeric GTP-binding proteins of the Ras superfamily that contain 4 highly conserved regions involved in GTP binding and hydrolysis. Rab proteins are prenylated, membrane-bound proteins involved in ve
miRNA miRNA information provided by mirtarbase database.
593 Show/Hide all (593)
miRTarBase ID miRNA Experiments Reference
MIRT039384 hsa-miR-421 CLASH 23622248
MIRT555018 hsa-miR-548an PAR-CLIP 21572407
MIRT555017 hsa-miR-4662a-3p PAR-CLIP 21572407
MIRT555016 hsa-miR-3194-3p PAR-CLIP 21572407
MIRT555015 hsa-miR-5691 PAR-CLIP 21572407
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
37 Show/Hide all (37)
GO ID Ontology Definition Evidence Reference
GO:0000139 Component Golgi membrane IBA
GO:0000139 Component Golgi membrane IEA
GO:0000166 Function Nucleotide binding IEA
GO:0000421 Component Autophagosome membrane IEA
GO:0001669 Component Acrosomal vesicle IEA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
607466 20246 ENSG00000129472
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q8WUD1
Protein name Ras-related protein Rab-2B (EC 3.6.5.2)
Protein function The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between active GTP-bound and inactive GDP-bound states. In their active state, dr
PDB 2A5J
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00071 Ras 8 → 169 Ras family Domain
Tissue specificity TISSUE SPECIFICITY: Expressed in kidney, prostate, lung, liver, thymus, colon, pancreas, and skeletal muscle, and low levels in placenta. Not detected in heart, brain, spleen, testis, ovary, small intestine and leukocyte.
Sequence
Sequence length 216
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
Reactome Pathway
RAB geranylgeranylation